Month: October 2021

Safety of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Base-Promoted Direct Synthesis of Sulfinates from N -Sulfonyl-hydrazones under Metal-Free Conditions published in 2020.0, Reprint Addresses Li, HJ; Wu, YC (corresponding author), Harbin Inst Technol, Sch Marine Sci & Technol, 2 Wenhuaxi Rd, Weihai 264209, Peoples R China.; Li, HJ; Wu, YC (corresponding author), Weihai Inst Marine Biomed Ind Technol, Weihai 264400, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

A base-promoted direct synthesis of sulfinates from N-sulfonylhydrazones is described. Various N-sulfonylhydrazones, derived from aldehydes and ketones, are converted into the corresponding sulfinates in moderate to good yields. This protocol possesses many advantages such as readily available and stable starting materials, broad substrate scope, and metal-free reaction conditions.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ji, YZ; Wu, QX; Li, HJ; Luo, DH; Wu, YC or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. In 2021.0 CHEMCATCHEM published article about LAYERED DOUBLE HYDROXIDE; CATALYZED ALPHA-ALKYLATION; RUTHENIUM-GRAFTED HYDROTALCITE; BAEYER-VILLIGER OXIDATION; NICKEL-IRON HYDROTALCITE; EFFICIENT CATALYSTS; ACCEPTORLESS DEHYDROGENATION; 2-AMINOBENZYL ALCOHOL; AEROBIC OXIDATION; MOLECULAR-OXYGEN in [Motokura, Ken; Ozawa, Nao; Manaka, Yuichi] Tokyo Inst Technol, Sch Mat & Chem Technol, Dept Chem Sci & Engn, Midori Ku, 4259 Nagatsuta Cho, Yokohama, Kanagawa 2268502, Japan; [Motokura, Ken] Japan Sci & Technol Agcy JST, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 3320012, Japan; [Manaka, Yuichi] Natl Inst Adv Ind Sci & Technol, Renewable Energy Res Ctr, 2-2-9 Machiikedai, Koriyama, Fukushima 9630298, Japan; [Chun, Wang-Jae] Int Christian Univ, Grad Sch Arts & Sci, Mitaka, Tokyo 1818585, Japan; [Motokura, Ken] Yokohama Natl Univ, Dept Chem & Life Sci, Hodogaya Ku, 79-5 Tokiwadai, Yokohama, Kanagawa 2408501, Japan in 2021.0, Cited 86.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The use of ubiquities elements such as iron instead of expensive precious metals as catalysts is one goal toward realizing environmentally benign synthetic chemistry. Here, we report that porous FeO(OH) dispersed on Mg-Al hydrotalcite acts as a bifunctional heterogeneous catalyst in the one-pot synthesis of 2-substituted quinoline derivatives through dehydrogenative oxidation-cyclization reactions. The catalyst was prepared by a simple grafting method using FeCl3 and Mg-Al hydrotalcite. The prepared porous FeO(OH) possesses a higher surface area than those previously reported for alpha-FeO(OH) particles. The one-pot quinoline synthesis proceeded effectively under non-noble-metal catalysis in air without requiring additional homogeneous bases or solvents.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Motokura, K; Ozawa, N; Sato, R; Manaka, Y; Chun, WJ or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. In 2019.0 CATAL LETT published article about LIGHT PHOTOCATALYTIC DEGRADATION; AG NANOPARTICLES; CARBON NANOTUBES; ACTIVATED CARBON; GRAPHENE OXIDE; METHYL-ORANGE; SELECTIVE REDUCTION; FACILE SYNTHESIS; REMOVAL; DYE in [Ansari, Sara; Khorshidi, Alireza] Univ Guilan, Dept Chem, Fac Sci, POB 41335-1914, Rasht, Iran; [Shariati, Shahab] Islamic Azad Univ, Dept Chem, Rasht Branch, Rasht, Iran in 2019.0, Cited 71.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Uniform dispersion of ultrafine spherical silver nanoparticles (NPs) was obtained over the surface of Fe3O4@SiO2@KIT-6 core-shell support via functionalization of the mesoporous KIT-6 shell by aminopropyltriethoxysilane, followed by coordination of Ag+ ions and in situ chemical reduction with sodium borohydride. The obtained hybrid material, Fe3O4@SiO2@KIT-6-Ag nanocomposite, was fully characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy, and used as an efficient catalyst for selective reduction of nitroaromatic compounds in aqueous solution at ambient temperature and neutral pH [nine examples, apparent rate constants at 25 degrees C, k (min(-1)), 0.112-0.628]. As a non-aromatic example, nitrofurazone which is a cytotoxic antibiotic was also reduced selectively at nitro group without reduction of other functionalities. Fe3O4@SiO2@KIT-6-Ag NPs also showed potential ability to act as catalyst for reduction of nitromethane in aqueous solution which can provide a colorimetric method for detection of nitromethane in solution down to 0.9×10(-4)molL(-1). Fe3O4@SiO2@KIT-6-Ag nanocomposite was also screened for its antibacterial activity, and satisfactory results were obtained in comparison with drug references including Tetracycline, Chloramphenicol and Cefotaxime as positive controls, on gram negative Escherichia coli and Pseudomonas aeroginosa. Ease of recycling of the Fe3O4@SiO2@KIT-6-Ag is another benefit of this nanocatalyst. Under the optimized conditions, the recycled catalyst showed 15% loss of efficiency after five successive runs. [GRAPHICS] .

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ansari, S; Khorshidi, A; Shariati, S or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Dearomatization and Functionalization of Terpyridine Ligands Leading to Unprecedented Zwitterionic Meisenheimer Aluminum Complexes and Their Use in Catalytic Hydroboration WOS:000458707000010 published article about ABUNDANT METAL-CATALYSTS; SINGLE-ELECTRON; HYDROGENATION; ALKYNES; IRON; REACTIVITY; CARBONYL; HYDRIDE; ACTIVATION; VERSATILE in [Zhang, Guoqi; Wu, Jing; Zeng, Haisu] CUNY, Grad Ctr, Dept Sci, John Jay Coll, New York, NY 10019 USA; [Zhang, Guoqi; Wu, Jing; Zeng, Haisu] CUNY, Grad Ctr, PhD Chem Program, New York, NY 10019 USA; [Wu, Jing; Zeng, Haisu; Neary, Michelle C.; Devany, Matthew; Zheng, Shengping] CUNY Hunter Coll, Dept Chem, New York, NY 10065 USA; [Dub, Pavel A.] Los Alamos Natl Lab, Los Alamos, NM 87545 USA in 2019.0, Cited 89.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

This paper reports the first example of dearomatization of ubiquitous terpyridine (tpy) ligands via 2’/6′-, 3/5′-, or 4′-selective alkylation of the central pyridine ring. The reaction is mediated by the most abundant metal in the Earth’s crust, aluminum (Al), and depending on the conditions employed, exhibits ionic or radical character as suggested by experimental and computational analysis. In the latter case, intermediate formation of an Al-III complex supported by pi-radical monoanionic ligand (tpy(center dot))(1-) is apparent. The 3’/5′-alkylation leads to unprecedented zwitterionic Meisenheimer Al-III complexes, which were identified as efficient precatalysts for the selective hydroboration of C=O and C equivalent to C functionalities. Turnover numbers (TONs) up to similar to 1000 place the corresponding complexes in the category of the most efficient Al catalysts reported to date for the title reaction. The acquired data suggest that aluminum monohydrides, or more likely dihydrides, could be relevant catalytic species. Alternatively, one can also imagine a mechanistic scenario in which the dearomatized chemically noninnocent ligand acts as hydride donor, and a detailed investigation of this is warranted in the future.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, GQ; Wu, J; Zeng, HS; Neary, MC; Devany, M; Zheng, SP; Dub, PA or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article 2-Thiopyrimidine/chalcone hybrids: design, synthesis, ADMET prediction, and anticancer evaluation as STAT3/STAT5a inhibitors WOS:000521276700001 published article about OVERCOME DRUG-RESISTANCE; CHALCONE DERIVATIVES; MOLECULAR TARGETS; LEUKEMIA; CANCER; STAT3; APOPTOSIS; POTENT; DOMAIN; SRC in [Lamie, Phoebe F.; Philoppes, John N.] Beni Suef Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Bani Suwayf 62514, Egypt in 2020.0, Cited 50.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A novel 2-thiopyrimidine/chalcone hybrid was designed, synthesised, and evaluated for their cytotoxic activities against three different cell lines, K-562, MCF-7, and HT-29. The most active cytotoxic derivatives were 9d, 9f, 9n, and 9p (IC50=0.77-1.74 mu M, against K-562 cell line), 9a and 9r (IC50=1.37-3.56 mu M against MCF-7 cell line), and 9a, 9l, and 9n (IC50=2.10 and 2.37 mu M against HT-29 cell line). Compounds 9a, 9d, 9f, 9n, and 9r were further evaluated for their cytotoxicity against normal fibroblast cell line WI38. Moreover, STAT3 and STAT5a inhibitory activities were determined for the most active derivatives 9a, 9d, 9f, 9n, and 9r. Dual inhibitory activity was observed in compound 9n (IC50=113.31 and 50.75 mu M, against STAT3 and STAT5a, respectively). Prediction of physicochemical properties, drug likeness score, pharmacokinetic and toxic properties was detected.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Lamie, PF; Philoppes, JN or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Carpentier, F; Felpin, FX; Zammattio, F; Le Grognec, E in AMER CHEMICAL SOC published article about CATALYZED SYNTHESIS; HYDRAZOIC ACID; CHEMISTRY; TETRAZOLES; REAGENTS; SAFE; CYCLOADDITION; SALTS in [Carpentier, Florian; Felpin, Francois-Xavier; Zammattio, Francoise; Le Grognec, Erwan] Univ Nantes, CNRS, CEISAM, UMR 6230, F-44000 Nantes, France in 2020, Cited 46. Formula: C14H11N. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

An efficient continuous flow process for the synthesis of 5-substituted 1H-tetrazoles is described. The process involves the reaction between a polymer-supported triorganotin azide and organic nitriles. The polymer-supported organotin azide, which is in situ generated with a polystyrene-supported triorganotin alkoxide and trimethylsilylazide, is immobilized in a packed bed reactor. This approach is simple, fast (it takes from 7.5 to 15 min), and guarantees a low concentration of tin residues in the products (<5 ppm). The process was developed to aryl-, heteroaryl-, and also alkylnitriles and was applied for the synthesis of valsartan, an angiotensin II receptor antagonist. Formula: C14H11N. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Carpentier, F; Felpin, FX; Zammattio, F; Le Grognec, E or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Preparation of palladated porous nitrogen-doped carbon using halloysite as porogen: disclosing its utility as a hydrogenation catalyst WOS:000559760300005 published article about PD NANOPARTICLES; NITROBENZENE HYDROGENATION; HETEROGENEOUS CATALYST; MESOPOROUS CARBON; GREEN SYNTHESIS; CLAY NANOTUBES; PALLADIUM; SUPPORT; FUNCTIONALIZATION; DEHYDROGENATION in [Sadjadi, Samahe] Iran Polymer & Petrochem Inst, Fac Petrochem, Gas Convers Dept, POB 14975-112, Tehran, Iran; [Malmir, Masoumeh; Heravi, Majid M.] Alzahra Univ, Sch Sci, Dept Chem, POB 1993891176, Tehran, Iran; [Lazzara, Giuseppe; Cavallaro, Giuseppe] Univ Palermo, Dipartimento Fis & Chim, Viale Sci,Pad 17, I-90128 Palermo, Italy; [Cavallaro, Giuseppe] INSTM, Consorzio Interuniv Nazl Sci & Tecnol Mat, Via G Giusti 9, I-50121 Florence, Italy in 2020.0, Cited 58.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In this article, halloysite nanoclay (Hal) was used as porogen for the synthesis of nitrogen doped porous carbon material with high specific surface area and pore volume. To this purpose, polymerization of melamine and terephthalaldehyde (MT) was performed in the presence of amine-functionalized carbon coated Hal (Hal@Glu-2N) that was prepared from hydrothermal treatment of Hal and glucose. Then, the prepared nanocomposite was palladated and carbonized to afford Pd@Hal@C. To further improve the textural properties of the nanocomposite, and introduce more pores in its structure, Hal nanotubes were etched. The characterization of the resulting compound, Pd@C, and comparing it with Pd@Hal@C, showed that etching of Hal significantly increased the specific surface area and pore volume in Pd@C. Pd@C was successfully used as a heterogeneous catalyst for promoting hydrogenation of nitroarens in aqueous media using hydrogen with atmospheric pressure as a reducing agent. The comparison of the structural features and catalytic activity of the catalyst with some control catalysts, including, Pd@Hal, Pd@Hal@Glu, Pd@Hal@Glu-MT and Pd@Hal@C confirmed that nitrogen groups in C could improve the Pd anchoring and suppress its leaching, while etching of Hal and introduction of more pores could enhance the catalytic activity through facilitating the mass transfer.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sadjadi, S; Malmir, M; Lazzara, G; Cavallaro, G; Heravi, MM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Titze, M; Heitkamper, J; Junge, T; Kastner, J; Peters, R in [Titze, Marvin; Junge, Thorsten; Peters, Rene] Univ Stuttgart, Inst Organ Chem, Pfaffenwaldring 55, D-70569 Stuttgart, Germany; [Heitkaemper, Juliane; Kaestner, Johannes] Univ Stuttgart, Inst Theoret Chem, Pfaffenwaldring 55, D-70569 Stuttgart, Germany published Highly Active Cooperative Lewis Acid-Ammonium Salt Catalyst for the Enantioselective Hydroboration of Ketones in 2021.0, Cited 70.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Enantiopure secondary alcohols are fundamental high-value synthetic building blocks. One of the most attractive ways to get access to this compound class is the catalytic hydroboration. We describe a new concept for this reaction type that allowed for exceptional catalytic turnover numbers (up to 15 400), which were increased by around 1.5-3 orders of magnitude compared to the most active catalysts previously reported. In our concept an aprotic ammonium halide moiety cooperates with an oxophilic Lewis acid within the same catalyst molecule. Control experiments reveal that both catalytic centers are essential for the observed activity. Kinetic, spectroscopic and computational studies show that the hydride transfer is rate limiting and proceeds via a concerted mechanism, in which hydride at Boron is continuously displaced by iodide, reminiscent to an S(N)2 reaction. The catalyst, which is accessible in high yields in few steps, was found to be stable during catalysis, readily recyclable and could be reused 10 times still efficiently working.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Titze, M; Heitkamper, J; Junge, T; Kastner, J; Peters, R or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 2,2-Diphenylacetonitrile. In 2020 J ORG CHEM published article about BOND FORMATION; HYDROXYPHTHALIMIDE SYNTHESIS; AMINO-ACIDS; ALDEHYDES; FUNCTIONALIZATION; ESTERIFICATION; DERIVATIVES; EFFICIENT; OLIGOMERIZATION; DIMERIZATION in [Krylov, Igor B.; Lopat’eva, Elena R.; Budnikov, Alexander S.; Nikishin, Gennady I.; Terent’ev, Alexander O.] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia; [Lopat’eva, Elena R.; Budnikov, Alexander S.] Mendeleev Univ Chem Technol Russia, 9 Miusskaya Sq, Moscow 125047, Russia in 2020, Cited 68. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

Cross-dehydrogenative C-O coupling of N-hydroxyimides with ketones, esters, and carboxylic acids was achieved employing the di-tertbutyl peroxide as a source of free radicals and a dehydrogenating agent. The proposed method is experimentally simple and demonstrates the outstanding efficiency for the challenging CH substrates, such as unactivated esters and carboxylic acids. It was shown that N-hydroxyphthalimide drastically affects the oxidative properties of t-BuOOt-Bu by intercepting the t-BuO center dot radicals with the formation of phthalimide-N-oxyl radicals, a species responsible for both hydrogen atom abstraction from the CH reagent and the selective formation of the C-O coupling product by selective radical cross-recombination. The practical applicability of the developed method was exemplified by the single-stage synthesis of commercial reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-hydroxysuccinimide, whereas in the standard synthetic approach, four stages are necessary.

Safety of 2,2-Diphenylacetonitrile. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Krylov, IB; Lopat’eva, ER; Budnikov, AS; Nikishin, GI; Terent’ev, AO or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about CORE-SHELL NANOPARTICLES; NI; REDUCTION; PD; HYDROGENATION; NITROBENZENE; NANOTUBES; NITROGEN; FABRICATION; NANOSHEETS, Saw an article supported by the Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [2042016HF1054]; Wuhan University Experiment Technology Project [WHU-2016-SYJS-06]. Computed Properties of C8H7NO3. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Zhao, X; Xiang, CJ; Zhang, FL; Yao, FZ; Sheng, RQ; Ding, Q; Liu, WJ; Zhang, HB; Zhou, XH. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

The increasing global demands for eco-friendly and low-cost catalysts have propelled the advent of nanosized non-noble-metal catalysts to replace traditional noble metals. In this work, ultrafine NiO nanoparticles were prepared rapidly in situ by the strategy of transforming three-dimensional (3D) metal boron organic polymers (BOPs@Ni2+) to one-dimensional (1D) boron organic polymers (BOPs@Ni) nanorod arrays at room temperature. The 3D BOPs@Ni2+ can be quickly obtained by the interaction of 4,4′-bipyridine with Ni2+ and dodecaborate (B12H122-) in an aqueous solution. When Ni2+ is converted into NiO in situ, 1D BOPs@Ni nanostructure transformation from the 3D BOPs@Ni2+ framework was achieved due to the B-H center dot center dot center dot pi interaction between B12H122- and 4,4′-bipyridine. Furthermore, BOPs@Ni exhibits high catalytic activity and rapid kinetics in the conversion of 4-nitrophenol to 4-aminophenol, and the high stability of 1D nanorod arrays guarantees the catalytic activity of BOP@Ni to barely change under recycling for at least 10 times. BOPs@Ni also exhibits good catalytic performance and high selectivity characteristics in the catalytic reduction of a series of nitrobenzene derivatives. This strategy of using BOPs@Ni2+ for loading self-supporting nanometal not only exhibits a highly efficient catalytic hydrogenation of nitrobenzene and its derivative but also provides an effective technical route for designing self-supported nanometal materials.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhao, X; Xiang, CJ; Zhang, FL; Yao, FZ; Sheng, RQ; Ding, Q; Liu, WJ; Zhang, HB; Zhou, XH or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem