Month: October 2021

Quality Control of 1-(4-Nitrophenyl)ethanone. Wang, HS; Zhao, WX; Du, J; Wei, FY; Chen, Q; Wang, XM in [Wang, Hongshe; Zhao, Weixing; Du, Juan; Wei, Fenyan; Chen, Qi; Wang, Xiaomei] Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Baoji 721013, Peoples R China published Cationic organotin cluster [t-Bu2Sn(OH)(H2O)](2)(2+)2OTf(-)-catalyzed one-pot three-component syntheses of 5-substituted 1H-tetrazoles and 2,4,6-triarylpyridines in water in 2019.0, Cited 46.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The cationic organotin cluster [t-Bu2Sn(OH)(H2O)](2)(2+)2OTf(-) is easy to prepare and stable in air. The catalytic activity of [t-Bu2Sn(OH)(H2O)](2)(2+)2OTf(-) as a neutral organotin Lewis acid catalyst is probed through the one-pot three-component syntheses of 5-substituted 1H-tetrazoles from aldehydes, hydroxylamine hydrochloride and sodium azide, and of 2,4,6-triarylpyridines from aromatic aldehydes, substituted acetophenones and ammonium acetate. The reactions proceed well in the presence of 1 mol% of [t-Bu2Sn(OH)(H2O)](2)(2+)2OTf(-) in water and provide the corresponding 5-substituted 1H-tetrazoles and 2,4,6-triarylpyridines in good to excellent yields. The method reported has several advantages such as the catalyst being neutral, low catalyst loading and use of water as a green solvent.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wang, HS; Zhao, WX; Du, J; Wei, FY; Chen, Q; Wang, XM or concate me.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Mehiaoui, N; Kibou, Z; Gallavardin, T; Leleu, S; Franck, X; Mendes, RF; Paz, FAA; Silva, AMS; Choukchou-Braham, N in SPRINGER published article about 2-PYRIDONE DERIVATIVES; DESIGN; AGENTS in [Mehiaoui, Nawel; Kibou, Zahira; Choukchou-Braham, Noureddine] Univ Tlemcen, Lab Catalyse & Synth Chim Organ, Fac Sci, BP 119, Tilimsen 13000, Algeria; [Kibou, Zahira] Ctr Univ Ain Temouchent, Inst Sci, BP 284, Ain Temouchent 46000, Algeria; [Gallavardin, Thibault; Leleu, Stephane; Franck, Xavier] Normandie Univ, CNRS, UNIROUEN, INSA Rouen,COBRA,UMR6014, F-76000 Rouen, France; [Gallavardin, Thibault; Leleu, Stephane; Franck, Xavier] Normandie Univ, CNRS, UNIROUEN, INSA Rouen,FR 3038, F-76000 Rouen, France; [Mendes, Ricardo F.; Paz, Filipe A. Almeida] Univ Aveiro, Dept Chem, CICECO Aveiro Inst Mat, P-3810193 Aveiro, Portugal; [Silva, Artur M. S.] Univ Aveiro, Dept Chem, QOPNA, P-3810193 Aveiro, Portugal; [Silva, Artur M. S.] Univ Aveiro, LAQV REQUIMTE, P-3810193 Aveiro, Portugal in 2021.0, Cited 44.0. Recommanded Product: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Novel substituted bis-(3-cyano-2-pyridone) derivatives were prepared via a powerful method using enaminonitriles push-pull dienes as key building blocks. The synthesis was performed in three steps from easily accessible starting materials in good yields. All target products were structurally elucidated by spectroscopic data. The reaction mechanism for formation of bis (3-cyano-2-pyridone) derivatives was proposed. The structures of enaminonitriles 3a and bis-pyridones 4c were confirmed by single-crystal X-ray diffraction. The florescent study of some bis (3-cyano-2-pyridones) derivatives was reported. [GRAPHICS]

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Mehiaoui, N; Kibou, Z; Gallavardin, T; Leleu, S; Franck, X; Mendes, RF; Paz, FAA; Silva, AMS; Choukchou-Braham, N or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 BIOORG CHEM published article about DIHYDROFOLATE-REDUCTASE INHIBITORS; ANTIOPPORTUNISTIC INFECTION AGENTS; DUAL THYMIDYLATE SYNTHASE; DERIVATIVES; ANTITUMOR; POTENT; DISCOVERY; DESIGN in [Wang, Fu-Cheng; Cao, Sheng-Li; Li, Hong-Yun; Yuan, Xiao-Li; Zhang, Ting-Ting] Capital Normal Univ, Dept Chem, Beijing 100048, Peoples R China; [Wang, Fu-Cheng; Cao, Sheng-Li; Li, Hong-Yun; Yuan, Xiao-Li; Zhang, Ting-Ting; Wang, Hailong; Li, Jing] Capital Normal Univ, Beijing Key Lab DNA Damage Response, Beijing 100048, Peoples R China; [Peng, Bin; Shi, Ruifeng; Li, Zhuqing; Liao, Ji; Xu, Xingzhi] Shenzhen Univ, Guangdong Key Lab Genome Stabil & Dis Prevent, Sch Med, Shenzhen 518060, Guangdong, Peoples R China; [Peng, Bin; Shi, Ruifeng; Li, Zhuqing; Liao, Ji; Xu, Xingzhi] Shenzhen Univ, Carson Int Canc Ctr, Sch Med, Shenzhen 518060, Guangdong, Peoples R China; [Peng, Bin; Shi, Ruifeng; Li, Zhuqing; Liao, Ji; Xu, Xingzhi] Shenzhen Univ, Marshall Lab Biomed Engn, Sch Med, Shenzhen 518060, Guangdong, Peoples R China; [Wang, Hailong; Li, Jing] Capital Normal Univ, Coll Life Sci, Beijing 100048, Peoples R China in 2020.0, Cited 31.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Many natural or synthetic chalcones have potential anti-tumor activity. Here, we synthesized two series of chalcone analogues containing a thieno [2,3-cflpyrimidin-2-y] group and evaluated for their cytotoxic activity towards cultured human lung cancer A549 and colorectal HCT-116 cells. Among them, compound 8d was the most cytotoxic against HCT-116 cells, with an IC50 value of 2.65 mu M. Analyses of the phenotypic changes induced by this compound found a dose-dependent accumulation of HCT-116 cells in sub-G1 phase, indicating that compound 8d might induce apoptosis. Furthermore, we found that 8d triggered mitochondrial membrane potential depolarization, promoted reactive oxygen species formation in HCT-116 cells, and increased the percentage of early and late apoptotic cells. Finally, immunoblotting indicated that 8d increased PARP-1 and caspases 3, 7 and 9 cleavage. These data suggest that compound 8d induces apoptosis via the mitochondrial death pathway.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wang, FC; Peng, B; Cao, SL; Li, HY; Yuan, XL; Zhang, TT; Shi, RF; Li, ZQ; Liao, J; Wang, HL; Li, J; Xu, XZ or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. Authors Ghosh, R; Jana, NC; Panda, S; Bagh, B in AMER CHEMICAL SOC published article about in [Ghosh, Rahul; Jana, Narayan Ch; Panda, Surajit; Bagh, Bidraha] HBNI, Natl Inst Sci Educ & Res NISER, Sch Chem Sci, Bhubaneswar 752050, Odisha, India in 2021, Cited 111. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Coordination of 1,4-disubstituted 1,2,3-triazoles L-1 and L-2 with [(p-cymene)RuCl2](2) followed by dehydrochlorination in the presence of a base resulted in the formation of complexes 1 and 2, respectively. Both were tested for the transfer hydrogenation of aldehydes and ketones in air using ecologically benign and cheap ethanol as the hydrogen source in the presence of a catalytic amount of a base. Air-stable complex 1 was proved to be an active catalyst for the transfer hydrogenation of a wide variety of aromatic and aliphatic aldehydes and ketones bearing various functionalities. Catalyst 1 was also effective for the transfer hydrogenation of carbonyls using the simplest primary alcohol, methanol, under aerobic conditions. Under the present catalytic protocol, labile or reducible functionalities such as nitro, cyano, and ester groups were tolerated. Good selectivity was also observed for acyclic alpha,beta-unsaturated carbonyls. However, this catalytic protocol was not selective for 2-cyclohexen-1-one as both alkene and keto moieties were reduced. The transfer hydrogenations are believed to proceed via a ruthenium-hydride intermediate. Finally, transfer hydrogenation of acetophenone using isopropanol as a commonly used hydrogen source was also performed and the sustainable and green credentials of these catalytic protocols utilizing methanol, ethanol, and isopropanol were compared with the help of the CHEM21 green metrics toolkit.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ghosh, R; Jana, NC; Panda, S; Bagh, B or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 CHEMISTRYSELECT published article about AROMATIC NITRO-COMPOUNDS; PHOTOCATALYTIC REDUCTION; CHEMOSELECTIVE REDUCTION; SELECTIVE HYDROGENATION; SUPPORTED PLATINUM; MESOPOROUS SBA-15; ACTIVE CATALYST; NANOPARTICLES; EFFICIENT; COPPER in [Thennila, Muthukumar; Muthumanickam, Shenbagapushpam; Selvakumar, Kodirajan] Thiagarajar Coll, Dept Chem Res, Madurai 625009, Tamil Nadu, India; [Thennila, Muthukumar; Sivabharathy, Madasamy] Sethu Inst Technol, Dept Phys, Virudunagar 626115, Tamil Nadu, India; [Yuvaraj, Paneerselvam] CSIR, North East Inst Sci & Technol, Branch Lab, Imphal 795004, Manipur, India in 2020.0, Cited 70.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. COA of Formula: C8H7NO3

A strategy for heterogeneous copper(I) mesoporous silica [Cu(I)-SBA-15] mediated catalytic reduction has been developed for the reduction of various nitroarenes in excellent yields. In addition to alcothermal strategy, other strategies have been attempted for the preparation of Cu(I) substituted mesoporous silica, however, the desired oxidation state is obtained only through alcothermal strategy. The crystalline phases and oxidation state of synthesized materials were characterized by XRD and XPS measurements and tested for catalytic reduction of nitroarenes. Among the tested materials, the best catalytic reduction of nitroarenes with an excellent substrate scope and good catalytic reusability was established by Cu(I)-SBA-15 material. The reduction kinetics and the controlled experimental studies reveal that the reaction proceeds through pseudo-first-order kinetics and nitrosobenzene intermediate pathway.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Thennila, M; Muthumanickam, S; Sivabharathy, M; Yuvaraj, P; Selvakumar, K or concate me.. COA of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article A Facile and Effective Procedure for Synthesis of Polyfunctionalized Bis (imidazolyl) Pyrrole/Imidazolyl Indole from Pyrrole/Indole with Arylglyoxals and N-aryl amidines WOS:000492694300006 published article about DERIVATIVES; ACID in [Masoudi, Mozhgan] Islamic Azad Univ, Dept Chem, Rafsanjan Branch, Rafsanjan, Iran; [Shahbazi-Manshadi, Mohammad Reza; Anary-Abbasinejad, Mohammad] Vali E Asr Univ, Dept Chem, Rafsanjan, Iran in 2019.0, Cited 20.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

Heterocyclic systems containing bis (imidazolyl) pyrrole or imidazolyl indole moieties were synthesized by heterocyclization of pyrrole or indole with arylglyoxal monohydrates and N-aryl amidines in ethanol catalyzed by FeCl3 at room temperature. The paper reports a facile, efficient, and environmentally friendly protocol for the synthesis of new products. Products were isolated by simple filtration, and their structures were established from their spectroscopic data.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Masoudi, M; Shahbazi-Manshadi, MR; Anary-Abbasinejad, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 J MOL LIQ published article about SODIUM-BOROHYDRIDE REDUCTIONS; CAPILLARY-ELECTROPHORESIS; ENANTIOSEPARATION in [Kaur, Nirmaljeet; Chopra, Harish Kumar] St Longowal Inst Engn & Technol, Dept Chem, Longowal 148106, India in 2020.0, Cited 38.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Formula: C8H7NO3

Chiral ionic liquids (CILs) have shown a wide range of applications in variety of domains in chemistry. Because of this, synthesis and applications of CILs have always been areas of interest for research in the last 20 years. Present work describes, the synthesis of six carbohydrate based chiral ionic liquids (CCILs) by following simple procedures and their applications. Structures of the cats were confirmed through various analytical techniques like NMR spectroscopy (H-1, C-13, B-11, P-31,F-19), El-MS, and polarimetry. Designed CCILs were tested as chiral recognising agents using sodium salt of Mosher’s acid as model substrate through (FNMR)-F-19-N- spectroscopy. Further, Cats were used as organocatalyst in the enantioselective reduction of aromatic prochiral ketones to achieve corresponding chiral secondary alcohols. (C) 2019 Elsevier B.V. All rights reserved.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Kaur, N; Chopra, HK or concate me.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. I found the field of Chemistry very interesting. Saw the article Pd@tetrahedral hollow magnetic nanoparticles coated with N-doped porous carbon as an efficient catalyst for hydrogenation of nitroarenes published in 2019.0, Reprint Addresses Sadjadi, S (corresponding author), Iran Polymer & Petrochem Inst, Fac Petrochem, Gas Convers Dept, 15Km Tehran Karaj Highway, Tehran 14975112, Iran.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

Hollow magnetic nanoparticles (MNPs) with tetrahedral morphology were synthesized and then covered by a shell prepared by coating with melamine-formaldehyde followed by the introduction of glucose-derived carbon. Subsequently, Pd nanoparticles were immobilized and the core-shell nanocomposite was carbonized. The obtained magnetic catalyst was successfully applied for the hydrogenation of nitroarenes in aqueous media. To investigate the effects of the morphology of MNPs, the nature of carbon shell, and the order of incorporation of Pd nanoparticles, several control catalysts, including the MNPs with different morphologies (disc-like and cylinder); MNPs coated with different shells (sole glucose-derived carbon or melamine-formaldehyde carbon shell); and a nanocomposite, in which Pd was immobilized after carbonization, were prepared and examined as catalyst for the model reaction. To justify the observed different catalytic activities of the catalysts, their Pd loadings, leaching, and specific surface areas were compared. The results confirmed that tetrahedral MNPs coated with porous N-rich carbon shell exhibited the best catalytic activity. The high catalytic activity of this catalyst was attributed to its high surface area and the interaction of N-rich shell with Pd nanoparticles that led to the higher Pd loading and suppressed Pd leaching.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sadjadi, S; Heravi, MM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 86-29-3. Authors Foster, D; Gao, PC; Zhang, ZY; Sipos, G; Sobolev, AN; Nealon, G; Falivene, L; Cavallo, L; Dorta, R in ROYAL SOC CHEMISTRY published article about in [Foster, Daven; Gao, Pengchao; Sipos, Gellert; Dorta, Reto] Univ Western Australia, Sch Mol Sci, Dept Chem, M310,35 Stirling Highway, Perth, WA 6009, Australia; [Zhang, Ziyun; Falivene, Laura; Cavallo, Luigi] King Abdullah Univ Sci & Technol, Chem & Life Sci & Engn, Kaust Catalysis Ctr, Thuwal 239556900, Saudi Arabia; [Sobolev, Alexandre N.; Nealon, Gareth] Univ Western Australia, Ctr Microscopy Characterisat & Anal, 35 Stirling Highway, Perth, WA 6009, Australia; [Sipos, Gellert] ComInnex Inc, Zahony Utca 7, H-1031 Budapest, Hungary; [Falivene, Laura] Univ Salerno, Dipartimento Chim, Via Giovanni Paolo II, I-84084 Fisciano, Italy in 2021, Cited 102. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

Chiral, cationic NHC-iridium complexes are introduced as catalysts for the intramolecular hydroamination reaction of unactivated aminoalkenes. The catalysts show high activity in the construction of a range of 5- and 6-membered N-heterocycles, which are accessed in excellent optical purity, with various functional groups being tolerated with this system. A major deactivation pathway is presented and eliminated by using alternative reaction conditions. A detailed experimental and computational study on the reaction mechanism is performed providing valuable insights into the mode of action of the catalytic system and pointing to future modifications to be made for this catalytic platform.

Product Details of 86-29-3. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Foster, D; Gao, PC; Zhang, ZY; Sipos, G; Sobolev, AN; Nealon, G; Falivene, L; Cavallo, L; Dorta, R or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Brito, CCB; da Silva, HVC; Brondanic, DJ; de Faria, AR; Ximenes, RM; da Silva, IM; de Albuquerque, JFC; Castilho, MS in TAYLOR & FRANCIS LTD published article about IRON SUPEROXIDE-DISMUTASE; TRYPANOSOMA-CRUZI; OPTIMIZATION; PROTEIN; ASSAYS; IDENTIFICATION; DENATURATION; CYTOTOXICITY; CALORIMETRY; STABILITY in [Bitencourt Brito, Camila C.; Castilho, Marcelo Santos] Univ Estadual Feira de Santana, Programa Posgrad Biotecnol, Feira De Santana, BA, Brazil; [Carneiro da Silva, Helder Vinicius; Ximenes, Rafael Matos; de Albuquerque, Julianna F. C.] Univ Fed Pernambuco, Dept Antibiot, Recife, PE, Brazil; [Brondanic, Daci Jose; de Faria, Antonio Rodolfo] Univ Fed Pernambuco, Dept Farm, Recife, PE, Brazil; [da Silva, Ivanildo Mangueira] Fac Belo Jardim, Recife, PE, Brazil; [Castilho, Marcelo Santos] Univ Fed Bahia, Fac Farm, Salvador, BA, Brazil in 2019.0, Cited 46.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Leishmaniasis is considered as one of the major neglected tropical diseases due to its magnitude and wide geographic distribution. Leishmania braziliensis, responsible for cutaneous leishmaniasis, is the most prevalent species in Brazil. Superoxide dismutase (SOD) belongs to the antioxidant pathway of the parasites and human host. Despite the differences between SOD of Leishmania braziliensis and human make this enzyme a promising target for drug development efforts. No medicinal chemistry effort has been made to identify LbSOD inhibitors. Herein, we show that thermal shift assays (TSA) and fluorescent protein-labeled assays (FPLA) can be employed as primary and secondary screens to achieve this goal. Moreover, we show that thiazole derivatives bind to LbSOD with micromolar affinity.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Brito, CCB; da Silva, HVC; Brondanic, DJ; de Faria, AR; Ximenes, RM; da Silva, IM; de Albuquerque, JFC; Castilho, MS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem