Month: November 2021

Authors Wang, B; Wang, LR; Liu, LL; Wang, W; Man, RJ; Zheng, DJ; Deng, YS; Yang, YS; Xu, C; Zhu, HL in ACADEMIC PRESS INC ELSEVIER SCIENCE published article about in [Wang, Bin; Wang, Li-Ren; Liu, Lu-Lu; Wang, Wei; Zheng, Da-Jun; Deng, Yu-Shan; Yang, Yu-Shun; Xu, Chen; Zhu, Hai-Liang] Nanjing Univ, Sch Life Sci, State Key Lab Pharmaceut Biotechnol, Nanjing 210023, Peoples R China; [Man, Ruo-Jun] Guangxi Univ Nationalities, Guangxi Biol Polysaccharide Separat Purificat & M, Nanning 530006, Peoples R China in 2021.0, Cited 44.0. HPLC of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In this work, a series of diaryl benzo[b][1,4]thiazepine derivatives D1-D36 were synthesized and screened as tubulin polymerization inhibitors with anti-tumor potency. They were designed by introducing the seven member ring benzothiazepine as the linker for CA-4 modification for the first time. Among them, the hit compound D8 showed potential on inhibiting the growth of several cancer cell lines (IC50 values: 1.48 mu M for HeLa, 1.47 mu M for MCF-7, 1.52 mu M for HT29 and 1.94 mu M for A549), being comparable with the positive controls Colchicine and CA-4P. The calculated IC50 value of D8 as an tubulin polymerization inhibitor was 1.20 mu M. The results of the flow cytometry assay revealed that D8 could induce the mitotic catastrophe and the death of living cancer cells. D8 also indicated the anti-vascular activity. The possible binding pattern was implied by docking simulation, inferring the possibility of introducing interactions with the nearby tubulin chain. Since the novel structural trial has been conducted with preliminary discussion, this work might stimulate new ideas in further modification of tubulin-related anti-cancer agents and therapeutic approaches.

Welcome to talk about 100-19-6, If you have any questions, you can contact Wang, B; Wang, LR; Liu, LL; Wang, W; Man, RJ; Zheng, DJ; Deng, YS; Yang, YS; Xu, C; Zhu, HL or send Email.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Understanding the role of surface Lewis acid sites of Sn modified Pd/Al2O3 catalyst in the chemoselective reductive N-acetylation of nitrobenzene published in 2020.0. Quality Control of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Akula, V (corresponding author), Indian Inst Chem Technol, CSIR, Catalysis & Fine Chem Div, Hyderabad 500007, Telangana, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

N-Aryl acetamides synthesis from the corresponding nitro compounds via a reductive N-acetylation was achieved over Pd supported on Sn modified Al2O3 catalyst using H-2, acetic anhydride as acetylating agent in aqueous media at ambient temperature. The pyridine-IR data demonstrated a majority of Lewis acid sites compared to Bronsted acid sites on the catalyst surface. Pyridine-IR and CO pulse chemisorption results emphasized a combination of surface palladium in conjunction with Lewis acid sites were responsible for the high activity of 2wt%Pd/5wt%Sn-Al2O3 over 2wt%Pd/Al2O3 catalyst with consistent activity and selectivity for four recycles. The bulk and surface properties of the catalysts were characterized by BET-SA, XRD, XPS, TPD of NH3, H-2-TPR, CO pulse chemisorption, TEM and the promotional effect of surface Lewis acid sites are rationalized by in situ pyridine adsorbed DRIFT spectroscopy.

Welcome to talk about 100-19-6, If you have any questions, you can contact Bilakanti, V; Gutta, N; Velisoju, VK; Dumpalapally, M; Inkollu, S; Nama, N; Akula, V or send Email.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Recently I am researching about H BOND FUNCTIONALIZATION; DIRECT OXYSULFONYLATION; SULFINIC ACIDS; KETO SULFONES; DIFUNCTIONALIZATION; CATALYSIS; ALKENES; ALKYNES; DERIVATIVES; STRATEGIES, Saw an article supported by the Research Council of Tarbiat Modares University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Yavari, I; Shaabanzadeh, S. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A synthesis of beta-ketosulfones via sulfination of aryl methyl ketones and aryl acetylenes with sodium sulfinates under mild electrochemical conditions, in moderate to good chemical yields, is described. In particular, an electrochemical sulfination reaction of alkynes with sulfinate salts has never been explored. An environmentally friendly characteristic of this reaction is that it uses electricity as a valuable energy source for electrochemical synthesis of beta-ketosulfones. This strategy is more convenient and practical compared to previous approaches.

Welcome to talk about 100-19-6, If you have any questions, you can contact Yavari, I; Shaabanzadeh, S or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMF via copper-catalyzed C(sp(3))-H amidination published in 2019.0. Quality Control of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Liu, Q; Guo, CC (corresponding author), Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp(3))-H amidination. Various methyl ketones react readily with aromatic amines and DMF, producing 2-oxo-acetamidines in yields of 47 to 92%. This protocol features the simultaneous formation of C-N and C?N bonds using DMF and aromatic amines as two different nitrogen sources. It thus provides an efficient approach to construct acyclic amidines via three C(sp(3))-H bond amidination. Based on the preliminary experiments, a plausible mechanism of this transformation is disclosed.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Metal-free Catalytic Esterification of Aryl Alkyl Ketones with Alcohols via Free-radical Mediated C(sp(3))-H Bond Oxygenation WOS:000616773300001 published article about BAEYER-VILLIGER OXIDATION; RETRO-CLAISEN CONDENSATION; C-NUCLEOSIDE SYNTHESIS; CARBON-CYANO; DIRECT CONVERSION; ORGANIC-ACIDS; HALLER-BAUER; CLEAVAGE; ESTERS; MILD in [Rammurthy, Banothu; Peraka, Swamy; Vasu, Amrutham; Sai, Gajula Krishna; Rohini, Yennamaneni Divya; Narender, Nama] Acad Sci & Innovat Res, CSIR HRDG Campus,Sect 19, Ghaziabad 201002, UP, India; [Rammurthy, Banothu; Peraka, Swamy; Vasu, Amrutham; Sai, Gajula Krishna; Rohini, Yennamaneni Divya; Narender, Nama] CSIR Indian Inst Chem Technol, C&FC Div, Hyderabad 500007, Telangana, India in 2021, Cited 88. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A novel metal-free catalytic one-pot approach has been developed for the esterification of aralkyl ketones with alcohols under open-air atmospheric conditions. The inexpensive iodide/oxone reagent system allowed the cascade C(sp(3))-H bond oxygenation, selective C-C bond cleavage and esterification through the both radical and ionic pathways in a stepwise manner in one-pot. This mild, convenient and economically viable catalytic method tolerates the various functional groups to provide the corresponding alkyl benzoates in up to 98% yields with up to 99% selectivity. The efficiency and feasibility of scale-up of the present catalytic system was demonstrated with gram scale experiments (up to 10 gram scale).

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Rammurthy, B; Peraka, S; Vasu, A; Sai, GK; Rohini, YD; Narender, N or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. Tejedor, D; Diana-Rivero, R; Garcia-Tellado, F in [Tejedor, David; Diana-Rivero, Raquel; Garcia-Tellado, Fernando] Inst Prod Nat & Agrobiol, Consejo Super Invest Cient, Astroffs Francisco Sanchez 3, San Cristobal la Laguna 38206, Spain; [Diana-Rivero, Raquel] Univ La Laguna, Doctoral & Postgrad Sch, Apartado Postal 456, San Cristobal la Laguna 38200, Spain published A General and Scalable Synthesis of Polysubstituted Indoles in 2020, Cited 84. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported. The protocol is based on the [3,3]-sigmatropic rearrangement of N-oxyenamines generated by the DABCO-catalyzed reaction of N-arylhydroxylamines and conjugated terminal alkynes, and delivers indoles endowed with a wide array of substitution patterns and topologies.

SDS of cas: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Tejedor, D; Diana-Rivero, R; Garcia-Tellado, F or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 BIOORG CHEM published article about IN-VITRO; POTENT INHIBITORS; DESIGN; ANALOGS; BIOLOGY in [Zaman, Khalid; Rahim, Fazal] Hazara Univ, Dept Chem, Mansehra 21300, Pakistan; [Taha, Muhammad] Imam Abdulrahman Bin Faisal Univ, IRMC, Dept Clin Pharm, POB 1982, Dammam 31441, Saudi Arabia; [Wadood, Abdul] Abdul Wali Khan Univ Mardan, Dept Biochem, Mardan 23200, Pakistan; [Shah, Syed Adnan Ali] Univ Teknol MARA UiTM, Atta Ur Rahman Inst Nat Prod Discovery, Puncak Alam Campus, Puncak Akan 42300, Selangor De, Malaysia; [Shah, Syed Adnan Ali] Univ Teknol MARA UiTM, Fac Pharm, Puncak Alam Campus, Puncak Alam 42300, Selangor Darul, Malaysia; [Gollapalli, Mohammed] Imam Abdulrahman Bin Faisal Univ, CCSIT, POB 1982, Dammam 3144, Saudi Arabia; [Ullah, Farhat] Univ Malakand, Dept Pharm, Khyber Pakhtunkhwa 18000, Kpk, Pakistan; [Ahmed, Ashfaq] Sarhad Univ Sci & Informat Technol, Dept Pharm, Peshawar, Pakistan in 2019.0, Cited 35.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

Isoquinoline analogues (KA-1 to 16) have been synthesized and evaluated for their E. coli thymidine phosphorylase inhibitory activity. Except compound 11, all other analogs showed outstanding thymidine inhibitory potential ranging in between 4.40 +/- 0.20 to 69.30 +/- 1.80 mu M when compared with standard drug 7-Deazaxanthine (IC50 = 38.68 +/- 4.42 mu M). Structure Activity Relationships has been established for all compounds, mainly based on substitution pattern on phenyl ring. All analogs were characterized by various spectroscopic techniques such as H-1 NMR, C-13 NMR and EI-MS. The binding interactions of isoquinoline analogues with the active site of TP enzyme, the molecular docking studies were performed. Furthermore, the angiogenic inhibitory potentials of isoquinoline analogues (KA-1-9, 14, 12 and 16) were determined in the presence of standard drug Dexamethasone based on percentage inhibitions at various concentrations. Herein this work analogue KA-12, 14 and 16 emerged with most potent angiogenic inhibitory potentials among the synthesized analogues.

Welcome to talk about 100-19-6, If you have any questions, you can contact Zaman, K; Rahim, F; Taha, M; Wadood, A; Shah, SAA; Gollapalli, M; Ullah, F; Ahmed, A or send Email.. Name: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 100-19-6. Recently I am researching about DRUG-DELIVERY SYSTEM; PHOTOREDOX CATALYSIS; HYDROGEN-PRODUCTION; METAL-COMPLEXES; ALKYLATION; ORGANOCATALYSIS; PHOTOOXIDATION; CHALLENGES; OXIDATION; DRIVEN, Saw an article supported by the Ministerio de Ciencia, Innovacion y Universidades from the Spanish Government [CTQ2015-64561-R, CTQ2015-66164-R]. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Gonzalez-Munoz, D; Casado-Sanchez, A; del Hierro, I; Gomez-Ruiz, S; Cabrera, S; Aleman, J. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

The grafting of a Pt(II) photocatalyst into three different mesoporous silica-based materials with different particle sizes and pore sizes was easily achieved through an amide bond formation. The analysis and results of the different characterization techniques showed that the catalyst is immobilized inside the pores of the materials and the photophysical properties of the catalyst are preserved after the covalent anchoring. The photocatalytic material catalyzed efficiently the debromination reaction of different substrates and is reused without detriment in its catalytic activity. In addition, the incorporation of the catalyst into mesoporous silica materials with different pore size allows the selective debromination of substrates by size discrimination. (C) 2019 Elsevier Inc. All rights reserved.

Product Details of 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020 ORG LETT published article about ASYMMETRIC-SYNTHESIS; ANALOGS; AMINES; TRANSFORMATION; HETEROCYCLES; PEPTIDES; ACIDS in [Zhang, Youcan; Yin, Zhiping; Wu, Xiao-Feng] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany in 2020, Cited 45. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Name: 2,2-Diphenylacetonitrile

A new methodology for the carbonylative transformation of N-fluoro-sulfonamides into N-sulfonyl-beta-homoproline esters has been described. In the presence of a catalytic amount of Cu(OTf)(2), a range of beta-homoproline derivatives were prepared in moderate to good yield. The reaction proceeds via the intramolecular cyclization and intermolecular carbonylation of a free carbon radical. Notably, this procedure offers the possibility to build potential functionalized bioactive molecules.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Zhang, YC; Yin, ZP; Wu, XF or concate me.. Name: 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 J ORG CHEM published article about 3+3 ANNULATION REACTION; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; MICHAEL ADDITION; CYCLIZATION REACTIONS; EFFICIENT SYNTHESIS; SPIROPYRAZOLONES; CASCADE; CYCLOADDITION; EPOXIDATION in [Shen, Shou-Jie; Du, Xiao-Li; Zhao, Ming-Gang] Shanxi Normal Univ, Key Lab Magnet Mol, Magnet Informat Mat Minist Educ, Sch Chem & Mat Sci, Linfen 041004, Peoples R China; [Xu, Xiao-Li; Liang, Jin-Yan] Shanxi Normal Univ, Coll Life Sci, Linfen 041004, Peoples R China in 2019.0, Cited 70.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

The regioselective N-addition/substitution reaction between alpha-alkylidene pyrazolinones and propargyl sulfonium salts has been developed to construct functionalized allylthio-containing pyrazolones with moderate to excellent yields. alpha-Alkylidene pyrazolinones act as N-nucleophilic agents which are distinguished from reported C-nucleophilic reactions. Excellent regioselectivity, readily available starting materials, the broad range of substrates, gram-scale synthesis, and simple operation illustrate the synthetic advantages of this new reaction pathway.

Quality Control of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Shen, SJ; Du, XL; Xu, XL; Zhao, MG; Liang, JY or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem