Month: January 2022

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. In 2020.0 J IRAN CHEM SOC published article about BIOLOGICAL EVALUATION; MOLECULAR DOCKING; DERIVATIVES; DESIGN; HYDRAZIDES; DISCOVERY; SAR in [Sanad, Sherif M. H.; Mekky, Ahmed E. M.] Cairo Univ, Fac Sci, Chem Dept, Giza 12613, Egypt in 2020.0, Cited 58.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The starting precursors 2-carbohydrazides, bearing thienopyridine moiety, were prepared using 2-thioxopyridine-3-carbonitriles as key synthons. Next, 2-carbohydrazides were reacted with a variety of 4-substituted benzylidinemalononitriles or 4-substituted benzaldehydes to afford a new series of the target hydrazones incorporating thienopyridine moiety. The elemental analyses and spectral data were used to demonstrate the structures of new hydrazones series. The in vitro antibacterial activities of the target hydrazones were evaluated against different strains of Gram-positive and Gram-negative bacteria. In comparison with chloramphenicol as a reference drug, hydrazones 13b, 13c and 13d, linked to p-C1, p-Br and p-Me moiety, respectively, exhibited the strongest activities against all tested bacteria with MIC values in the range of 6.2-12.5 mu g/mL. In addition, several new hydrazones were tested as in vitro cytotoxic agents against each of human breast carcinoma MCF-7 cell line, colon cancer Caco2 cell line and liver hepatocellular carcinoma HEPG2 cell line. The hydrazones 13b, 13c and 13d demonstrated the best cytotoxicity against the tested eukaryotic cells. Furthermore, both experimental and docking studies could predict the promising inhibitory activities of hydrazones 13c and 13d against COX-2 enzyme with IC 50 of 0.110 and 0.104 mu M, respectively, when compared with Celecoxib (IC50 of 0.115 mu M). [GRAPHICS] .

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sanad, SMH; Mekky, AEM or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Theoretical and computational insight into the supramolecular assemblies of Schiff bases involving hydrogen bonding and C-H center dot center dot center dot pi interactions: Synthesis, X-ray characterization, Hirshfeld surface analysis, anticancer activity and molecular docking analysis published in 2021.0, Reprint Addresses Andleeb, H; Hameed, S (corresponding author), Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan.; Andleeb, H (corresponding author), Int Islamic Univ, Fac Basic & Appl Sci, Sulaiman Bin Abdullah Aba Al Khail Ctr Interdisci, Islamabad, Pakistan.; Khan, I (corresponding author), Univ Manchester, Dept Chem, 131 Princess St, Manchester M1 7DN, Lancs, England.; Khan, I (corresponding author), Univ Manchester, Manchester Inst Biotechnol, 131 Princess St, Manchester M1 7DN, Lancs, England.; Simpson, J (corresponding author), Univ Otago, Dept Chem, POB 56, Dunedin 9054, New Zealand.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

The present study examines the significance of various non-covalent interactions in the supramolecular assembly of (E)-1-(1-(4-nitrophenyl)ethylidene)-2-phenylhydrazine 1c and (E)-3-bromo-N’-(1-phenylethylidene)benzohydrazide 2d. The synthesized compounds were fully characterized by spectroscopic methods and single crystal X-ray diffraction analysis. The topology of the supramolecular assemblies was controlled by various non-covalent interactions including classical hydrogen bonding, C-H center dot center dot center dot pi and Br center dot center dot center dot Br interactions which were examined in detail using several theoretical methods and DFT calculations. The optimized geometric parameters of compounds 1c and 2d were calculated using density functional theory (DFT/B3LYP) quantum chemical method with the 6-311++G(d,p) basis set using the crystallographic coordinates. Additionally, fragments contributing to the HOMO and LUMO molecular orbitals were investigated at the same level of theory. The nature and various types of intermolecular interactions in the crystal structures was also investigated by Hirshfeld surface analysis. The synthesized Schiff bases were also studied for their potential as drugs and physicochemical properties. Bioevaluation against four cancer cell lines (NCI-H460, NCI-H460/Bcl-2, MDA-MB-231 and MCF-7) showed that compound 1c was a more potent inducer of toxicity compared to 2d. The putative binding modes of the bioactive Schiff bases were investigated using molecular docking tools and the results revealed that both the inhibitors were stabilized in the active pocket of the enzyme via the formation of various interactions with the key amino acid residues. (C) 2021 Elsevier B.V. All rights reserved.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Andleeb, H; Danish, L; Munawar, S; Ahmed, MN; Khan, I; Ali, HS; Tahir, MN; Simpson, J; Hameed, S or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about POLYETHYLENE-GLYCOL; BIOLOGICAL EVALUATION; THIAZOLE DERIVATIVES; ORGANIC-SYNTHESIS; IN-VITRO; SOLVENT; PEG, Saw an article supported by the . Recommanded Product: 1-(4-Nitrophenyl)ethanone. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Adole, VA; More, RA; Jagdale, BS; Pawar, TB; Chobe, SS. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

In the present investigation, an alluring green PEG-400 mediated one-pot synthesis of novel 2-(2-hydrazinyl)thiazole derivatives from 1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one has been unveiled via a novel synthetic pathway. The application of PEG in organic reactions as a reaction media is one of the fantastic tools of green chemistry as reactions can be carried out under generous conditions limiting environmental peril and chemical waste. PEG-400 is recognized as a low-cost, non-flammable, environmentally benign, recyclable, and richly available green solvent. A series of novel 2-(2-hydrazineyl)thiazole derivatives have been synthesized in good to excellent yield by using the green capability of PEG-400 solvent. These newly synthesized compounds were tested for their antimicrobial and antioxidant activities. The results revealed that these compounds show good activities compared with the standard. Additionally, all the synthesized compounds exhibit negligible cytotoxicity as compared to the positive control. The structures of all novel compounds reported herein are established using FT-IR, H-1 NMR, C-13 NMR, D2O exchange experiment and HRMS techniques.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Adole, VA; More, RA; Jagdale, BS; Pawar, TB; Chobe, SS or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about TRANSFER HYDROGENATION; AROMATIC-COMPOUNDS; PD NANOPARTICLES; GRAPHENE OXIDE; AMMONIA BORANE; CARBON; NITROARENES, Saw an article supported by the Shandong Provincial Natural Science Foundation, ChinaNatural Science Foundation of Shandong Province [ZR2019BC011]; Opening Project of Shandong Eco-chemical Engineering Collaborative Innovation Center [XTCXQN14]; Taishan Scholars Projects of Shandong [ts201511033]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21805158]; 13th National 5-year R&D plans in rural areas [2016YFD0600804]; Key R&D project of Shandong [2018GSF121031]. Published in ELSEVIER in AMSTERDAM ,Authors: Liu, Y; Yin, DF; Xin, QH; Lv, MX; Bian, B; Li, L; Xie, CX; Yu, ST; Liu, SW. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. HPLC of Formula: C8H7NO3

A supported ruthenium (Ru) nanoparticle on amino-functionalized Fe3O4 (Fe3O4/NH2/Ru) was successfully prepared by a novel and simple one-pot template-free method combined with a metal adsorption-reduction procedure. The characterization results show that the introduced amino group (1,6-hexanediamine) can effectively stabilize the Ru nanoparticles and allow the particles to maintain a narrow size distribution, monodispersity and a regular morphology. Fe3O4/NH2/Ru exhibits excellent catalytic activity for the transfer hydrogenation of nitro compounds by the use of NaBH4 as the hydrogen donor. The higher activity of this catalyst was attributed to the higher dispersion and smaller particle size of Ru nanoparticles, as observed from the characterization results. Moreover, the catalyst can be easily recovered by an external magnetic field, recycled five times and reused without any loss of activity.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Copper-Catalyzed Oxidative Synthesis of alpha-Ketoamides from Aryl Methyl Ketones and N-Bromobutanimide Using N,N-Dimethylformamide as Dimethylamine Source WOS:000516603100016 published article about ONE-POT SYNTHESIS; METAL-FREE; TERMINAL ALKYNES; SECONDARY-AMINES; AMIDATION; ACETOPHENONES; FORMAMIDES; ANILINES in [Wei, Ying] Nanjing Univ Posts & Telecommun, CMSOD, KLOEID, Nanjing 210023, Jiangsu, Peoples R China; Nanjing Univ Posts & Telecommun, IAM, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Nanjing 210023, Jiangsu, Peoples R China in 2020.0, Cited 27.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A novel and practical Cu(OAc)(2)-catalyzed oxidative synthesis of.-ketoamides from aryl methyl ketones and N-bromobutanimide (NBS) using N,N-dimethylformamide (DMF) as dimethylamine (HNMe2) source and solvent has been developed under mild conditions. DMF was used as a HNMe2 source and can be easily converted into HNM(e)2 by acid hydrolysis. The mechanistic studies indicate that Cu(OAc)(2) plays a dual role in providing both catalyst and oxidant.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Wei, Y; Yan, YX; Li, XY or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. In 2019.0 INORG CHEM COMMUN published article about N-HETEROCYCLIC CARBENES; C-C; PROPARGYLIC ESTERS; TRIAZOLE-GOLD; CATALYTIC APPLICATION; EFFICIENT; AU; CYCLOISOMERIZATION; ALCOHOLS; REARRANGEMENT in [Hu, Wenkang; Yang, Yongchun; Wang, Dawei] Jiangnan Univ, Sch Chem & Mat Engn, Minist Educ, Key Lab Synthet & Biol Colloid, Wuxi 214122, Jiangsu, Peoples R China; [Shan, Liang] Jiangnan Univ, Sch Food Sci & Technol, J, Wuxi 214122, Jiangsu, Peoples R China; [Ma, Fudong] Xinjiang Agr Univ, Chem Engn Coll, Urumqi 830052, Peoples R China; [Zhang, Yilin] West Virginia Univ, C Eugene Bennett Dept Chem, Morgantown, WV 26506 USA in 2019.0, Cited 89.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The methyl 1H-1,2,3-triazole-4-carboxylate containing a strong electron-withdrawing group was developed and applied as a ligand for gold(I) cations. The resulting ester-triazole gold(I) complex was investigated for its efficiency in catalyzing allene synthesis and alkyne hydration, in which an excellent catalytic efficiency was observed with low catalyst loadings.

HPLC of Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Hu, WK; Shan, L; Ma, FD; Zhang, YL; Yang, YC; Wang, DW or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Highly Selective Hydroboration of Carbonyls by a Manganese Catalyst: Insight into the Reaction Mechanism WOS:000576677500011 published article about ASYMMETRIC REDUCTION; EFFICIENT CATALYST; KETONES; ALDEHYDES; HYDROSILYLATION; COMPLEXES; HYDRIDE; RUTHENIUM; POLY(SILYLETHER)S; HYDROGENATION in [Vijjamarri, Srikanth; O’Denius, Timothy M.; Yao, Bin; Kubatov, Alena; Du, Guodong] Univ North Dakota, Dept Chem, Grand Forks, ND 58202 USA in 2020.0, Cited 81.0. COA of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Hydroboration of carbonyl compounds is an important transformation in organic chemistry, and a growing interest in catalysis has focused on abundant and nontoxic base metals. Herein we describe an efficient salen manganese catalyst for the hydroboration of a broad range of carbonyl compounds with pinacolborane. The catalytic reactions proceeded rapidly (>99% conversion in <5 min) at room temperature with very low catalyst loadings. High turnover frequency (up to 5700 h(-1)) was observed under these conditions. Several synthetically important functional groups were tolerated, and chemoselective hydroboration of aldehydes over ketones was achieved. The H/D kinetic isotopic effect of borane was determined to be 2.3. The Hammett correlation plot of a series of para-substituted acetophenone substrates, p-X-C6H6COCH3 (X = H, Me, OMe, NO2, Cl, Br, and CF3) yielded a positive slope of rho = +0.99. The crossover products were detected in the competition reaction of catecholborane and deuterated pinacolborane with acetophenone. The findings indicated a potential borane-mediated pathway that could account for the observation of the crossover products. COA of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Vijjamarri, S; O’Denius, TM; Yao, B; Kubatov, A; Du, GD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Chemoselective Hydrogenation of 4-Nitrostyrene to 4-Aminostyrene by Highly Efficient TiO2 Supported Ni3Sn2 Alloy Catalyst WOS:000462602700003 published article about SELECTIVE HYDROGENATION; NITRO-COMPOUNDS; PD/SIO2 CATALYSTS; NITROARENES; NANOPARTICLES; REDUCTION; AMINES; SN; CINNAMALDEHYDE; OXIDE in [Yamanaka, Nobutaka; Hara, Takayoshi; Ichikuni, Nobuyuki; Shimazu, Shogo] Chiba Univ, Dept Appl Chem & Biotechnol, Grad Sch Engn, Inage Ku, 1-33 Yayoi Cho, Chiba 2638522, Japan in 2019.0, Cited 40.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Safety of 1-(4-Nitrophenyl)ethanone

Ni3Sn2 alloy catalysts supported on various metal oxides (TiO2, Al2O3, ZrO2, SnO2, and CeO2) were successfully prepared by simple hydrothermal method and then applied to the hydrogenation of 4-nitrostyrene under H-2 3.0 MPa at 423 K. All the supported catalysts hydrogenated the nitro group more preferentially than the olefin group from the initial reaction stages, showing 100% chemoselectivities towards the desired 4-aminostyrene. This may be attributed to sigma-interaction between the oxygen lone pairs in the nitro group and Sn atoms in Ni3Sn2 alloy. By prolonging the reaction times, the 4-aminostyrene yields increased and finally reached the maximum yields. Among the catalysts, Ni3Sn2/TiO2 alloy catalyst showed the highest catalytic activity with remarkably high chemoselectivity towards 4-aminostyrene. The conversion and chemoselectivity were 100% and 79%, respectively, at a reaction time of only 2.5 h. From the physical and chemical characterization of the supported catalysts, it was clear that the catalytic activity was correlated with H-2 uptake. The application of the best catalyst for the hydrogenation of a wide variety of substituted nitroarenes resulted in the chemoselective formation of the corresponding aminoarenes.

Welcome to talk about 100-19-6, If you have any questions, you can contact Yamanaka, N; Hara, T; Ichikuni, N; Shimazu, S or send Email.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020 J ORG CHEM published article about TRANS-HYDROBORATION; HYDRIDE; ALKENES; REDUCTION; COMPLEXES; EFFICIENT; IMINES in [Sarkar, Nabin; Bera, Subhadeep; Nembenna, Sharanappa] Homi Bhabha Natl Inst, Sch Chem Sci, Natl Inst Sci Educ & Res, Bhubaneswar 752050, Odisha, India in 2020, Cited 58. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Name: 2,2-Diphenylacetonitrile

The reaction of LH [L = {(ArNH)(ArN)-C=N-C=(NAr)(NHAr)}; Ar =2,6-Et-2-C6H3] with a commercially available alane amine adduct (H3Al center dot NMe2Et) in toluene resulted in the formation of a conjugated bis-guanidinate (CBG)-supported aluminum dihydride complex, i.e., LAIH(2) (1), in good yield. The new complex has been thoroughly characterized by multinuclear magnetic resonance, IR, mass, and elemental analyses, including single-crystal structural studies. Further, we have demonstrated the aluminum-catalyzed hydroboration of a variety of nitriles and alkynes. Moreover, aluminum-catalyzed hydroboration is expanded to more challenging substrates such as alkene, pyridine, imine, carbodiimide, and isocyanides. More importantly, we have shown that the aluminum dihydride catalyzed both intra- and intermolecular chemoselective hydroboration of nitriles and alkynes over other reducible functionalities for the first time.

Name: 2,2-Diphenylacetonitrile. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Giboulot, S; Baldino, S; Ballico, M; Figliolia, R; Pothig, A; Zhang, SM; Zuccaccia, D; Baratta, W in AMER CHEMICAL SOC published article about ASYMMETRIC TRANSFER HYDROGENATION; CHEMOSELECTIVE TRANSFER HYDROGENATION; LIGAND BIFUNCTIONAL CATALYSIS; C BOND FORMATION; HOMOGENEOUS RUTHENIUM; MECHANISTIC ASPECTS; 2-(AMINOMETHYL) PYRIDINE; COMPLEXES SYNTHESIS; PHOSPHINE-LIGANDS; OSMIUM COMPLEXES in [Giboulot, Steven; Baldino, Salvatore; Ballico, Maurizio; Figliolia, Rosario; Zhang, Shuanming; Zuccaccia, Daniele; Baratta, Walter] Univ Udine, Dipartimento DI4A, Via Cotonificio 108, I-33100 Udine, Italy; [Baldino, Salvatore] Univ Torino, Dipartimento Chim, Via Pietro Giuria 7, I-10125 Turin, Italy; [Giboulot, Steven] Johnson Matthey, 28 Cambridge Sci Pk,Milton Rd, Cambridge CB4 0FP, England; [Poethig, Alexander] Tech Univ Munich, Dept Chem, Lichtenbergstr 4, D-85747 Garching, Germany; [Poethig, Alexander] Tech Univ Munich, Catalysis Res Ctr, Lichtenbergstr 4, D-85747 Garching, Germany; [Zhang, Shuanming] JITRI, 699 Xuanwu Ave, Nanjing 210008, Jiangsu, Peoples R China in 2019.0, Cited 158.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The bidentate HCNN dicarbonyl ruthenium complexes trans,cis-[RuCl2(HCNN)(CO)(2)] (1-3) and trans,cis-[RuCl2(ampy)(CO)(2)] (1a) were prepared by reaction of [RuCl2(CO)(2)](n) with 1-[6-(4′-methylphenyl)pyridin-2-yl]methanamine, benzo[h]quinoline (HCNN), and 2-(aminomethyl)pyridine (ampy) ligands. Alternatively, the derivatives 13 were obtained from the reaction of RuCl3 hydrate with HCO2H and HCNN. The pincer CNN cis-[RuCl(CNN)(CO)(2)] (4) was isolated from 1 by reaction with NEt3. The monocarbonyl complexes trans-[RuCl2(HCNN)(PPh3)(CO)] (5-7) were synthesized from [RuCl2(dmf)(PPh3)2(CO)] and HCNN ligands, while the diacetate trans-[Ru(OAc)(2)(HCNN)(PPh3)(CO)] (8) was obtained from [Ru(OAc)(2)(PPh3)(2)(CO)]. Carbonylation of cis-[RuCl(CNN)(PPh3)(2)] with CO afforded the pincer derivatives [RuCl(CNN)(PPh3)(CO)] (9-11). Treatment of 9 with Na[BArf](4) and PPh3 gave the cationic complex trans-[Ru(CNN)(PPh3)(2)(CO)][BAr4f] (12). The dicarbonyl derivatives 1-4, in the presence of PPh3 or PCy3, and the monocarbonyl complexes 5-12 catalyzed the transfer hydrogenation (TH) of acetophenone (a) in 2-propanol at reflux (S/C = 1000100000 and TOF up to 100000 h(-1)). Compounds 13, with PCy3, and 6 and 8-10 were proven to catalyze the TH of carbonyl compounds, including alpha,beta-unsaturated aldehydes and bulky ketones (S/C and TOF up to 10000 and 100000 h(-1), respectively). The derivatives 1-3 with PCy3 and 5 and 6 catalyzed the hydrogenation (HY) of a (H-2, 30 bar) at 70 degrees C (S/C = 2000-10000). Complex 5 was active in the HY of diaryl ketones and aryl methyl ketones, leading to complete conversion at S/C = 10000.

Welcome to talk about 100-19-6, If you have any questions, you can contact Giboulot, S; Baldino, S; Ballico, M; Figliolia, R; Pothig, A; Zhang, SM; Zuccaccia, D; Baratta, W or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem