Safety of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Stereoselective synthesis of trifluoromethyl-substituted 2H-furan-amines from enaminones published in 2020.0, Reprint Addresses Loh, TP; Jiang, YJ (corresponding author), Nanjing Tech Univ, Inst Adv Synth, Nanjing 211816, Peoples R China.; Loh, TP (corresponding author), Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637616, Singapore.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.
A straightforward strategy for synthesis of highly functionalized trifluoromethyl 2H-furans is described. The copper catalyzed method relies on a cascade cyclic reaction between enaminones and N-tosylhydrazones. This method allows the synthesis of 2-amino-3-trifluoromethyl-substituted 2H-furan derivatives carrying a quaternary stereogenic center as single diastereomers. The proposed reaction mechanism involves an amino-cyclopropane intermediate formed in the cyclopropanation of enaminones. The developed method tolerates a broad spectrum of functionalities, and the obtained 2H-furan derivatives are useful synthetic intermediates for preparing other trifluoromethyl-substituted compounds.
Welcome to talk about 100-19-6, If you have any questions, you can contact Liang, XY; Guo, P; Yang, WJ; Li, M; Jiang, CZ; Sun, WB; Loh, TP; Jiang, YJ or send Email.. Safety of 1-(4-Nitrophenyl)ethanone
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem