Kondori, Tahere; Ghaznavi, Habib; Afshari, Fahimeh; Shahraki, Sheida; Shahraki, Jafar; Dusek, Michal; Kucerakova, Monika; Shahraki, Omolbanin published the article 《A novel Au(III) complex with the 5,5′-dimethyl-2,2′-bipyridine ligand: Synthesis, characterization, X-ray crystal structure and biological evaluation》. Keywords: gold dimethylbipyridine chloro complex preparation crystal structure DNA interaction; mol docking gold dimethylbipyridine chloro complex; antitumor activity gold dimethylbipyridine chloro complex.They researched the compound: 5,5′-Dimethyl-2,2′-bipyridine( cas:1762-34-1 ).Name: 5,5′-Dimethyl-2,2′-bipyridine. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1762-34-1) here.
A novel gold complex: [Au(5 5′-dmbipy)(Cl)2] (a) which dmbipy is 5, 5′-Dimethyl-2, 2′-bipyridine was synthesized and different techniques were applied to confirm the chem. structure. The structure consists of a gold cation chelated by one neutral bipyridine ligand two (Cl-) ions and one (Cl-) ion inside and outside of the coordination sphere, resp. Thermodn. parameters (ΔH° ΔS° and ΔG°) calculated from FS-DNA interaction of complex showed that electrostatic binding have an essential function in the interaction of DNA-Au(III) complex. Addnl. relative viscosity of DNA did not change while the concentration increased. As proved by CD spectra the DNA structure changed. The synthesized compound exhibited an effective cytotoxic behavior against cancerous cell lines. The mol. docking exploration indicated the non-intercalative mode of binding which confirms the obtained results from spectroscopy viscometry and CD techniques.
As far as I know, this compound(1762-34-1)Name: 5,5′-Dimethyl-2,2′-bipyridine can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.