An article Highly Enantioselective Transfer Hydrogenation of Prochiral Ketones Using Ru(II)-Chitosan Catalyst in Aqueous Media WOS:000459734900023 published article about ASYMMETRIC TRANSFER HYDROGENATION; HETEROGENEOUS CATALYSTS; PALLADIUM-CHITOSAN; CHIRAL LIGANDS; COMPLEXES; ALCOHOLS; WATER; DERIVATIVES; IRIDIUM; CHITIN in [Szollosi, Gyoergy] Univ Szeged, MTA SZTE Stereochem Res Grp, Dom Ter 8, H-6720 Szeged, Hungary; [Szollosi, Gyoergy] Univ Szeged, Interdisciplinary Excellence Ctr, Inst Pharmaceut Chem, Eotvos U 6, H-6720 Szeged, Hungary; [Kolcsar, Vanessza Judit] Univ Szeged, Dept Organ Chem, Dom Ter 8, H-6720 Szeged, Hungary in 2019.0, Cited 118.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6
Unprecedentedly high enantioselectivities are obtained in the transfer hydrogenation of prochiral ketones catalyzed by a Ru complex formed insitu with chitosan chiral ligand. This biocompatible, biodegradable chiral polymer obtained from the natural chitin afforded good, up to 86% enantioselectivities, in the aqueous-phase transfer hydrogenation of acetophenone derivatives using HCOONa as hydrogen donor. Cyclic ketones were transformed in even higher, over 90%, enantioselectivities, whereas further increase, up to 97%, was obtained in the transfer hydrogenations of heterocyclic ketones. The chiral catalyst precursor prepared ex situ was examined by scanning electron microscopy, FT-mid- and -far-IR spectroscopy. The structure of the insitu formed catalyst was investigated by H-1 NMR spectroscopy and using various chitosan derivatives. It was shown that a Ru pre-catalyst is formed by coordination of the biopolymer to the metal by amino groups. This precursor is transformed in water insoluble Ru-hydride complex following hydrogen donor addition. The practical value of the developed method was verified by preparing over twenty chiral alcohols in good yields and optical purities. The catalyst was applied for obtaining optically pure chiral alcohols at gram scale following a single crystallization.
Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Szollosi, G; Kolcsar, VJ or send Email.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem