Category: 100-19-6

An article Ni-Au alloy nanoparticles as a high performance heterogeneous catalyst for hydrogenation of aromatic nitro compounds WOS:000467235800033 published article about CHEMOSELECTIVE HYDROGENATION; SELECTIVE HYDROGENATION; GOLD; METAL; REDUCTION; EFFICIENT; AZO in [Lang, Leiming; Pan, Zhaorui; Yan, Jun] Nanjing Xiaozhuang Univ, Lab Adv Funct Mat Nanjing, Nanjing 211171, Jiangsu, Peoples R China; [Lang, Leiming] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China in 2019.0, Cited 30.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Selective hydrogenation of nitro compounds requires highly active and less expensive materials as a heterogeneous catalyst. As a good candidate, the Ni-Au alloy nanoparticles (NPs) have been synthesized by simple in-situ reduction method, which was loaded to the active carbon with 10 wt % loading amount. The Ni-Au/C catalyst shows superior catalytic performance for hydrogenation of nitro compounds with 100% conversion and selectivity without any by-products, which also indicates good recycle performance for several times use. The prepared catalyst not only reduces the usage amount of noble metal, but also keeps the high catalytic activity, which is a promising catalyst for industry applications. (C) 2019 Elsevier B.V. All rights reserved.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Lang, LM; Pan, ZR; Yan, J or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Design, synthesis, and evaluation of novel combretastatin A-4based chalcone derivatives as anticancer agents WOS:000591550900001 published article about ANTIMITOTIC NATURAL-PRODUCTS; BIOLOGICAL EVALUATION; COLCHICINE SITE; ANALOGS; TUBULIN; BINDING; CYTOTOXICITY; INHIBITION; FLAVONOIDS; MECHANISM in [Rathnakar, Bethi; Kumar, Gajula S.; Mahammad, Saleem P.; Nimma, Rameshwar; Satyanarayana, Mavurapu] Telangana Univ, Dept Pharmaceut Chem, Nizamabad, India; [Gattu, Sridhar] CSIR IICT, Organ & Biomol Div, Hyderabad, India; [Kalyani, Sambaru] Mahatma Gandhi Univ, Dept Chem & Pharmaceut Sci, Nalgonda, India in 2021.0, Cited 55.0. COA of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A series of combretastatin A-4 based chalcones (14a-l) were designed, synthesized and these compounds examined for inhibitory effects on the proliferation of human lung (A549), breast (MCF-7), melanoma (A375), and colon (HT-29) carcinoma cells. Compounds 14b, 14c, 14e, 14h, and 14i (tri/dimethoxy, methyl, and mono/dinitro derivatives) have exhibited the most potent antiproliferative activity with IC50 < 2 mu M and the hexa methoxy derivative 14b, the most promising one, which displayed the potent inhibitory activities in MCF-7 (IC50: 10 nM), A375 (IC50: 12 nM), and A549 (IC50: 65 nM) cell lines, and is 18 times more potent than the CA-4. Compound 14b represents a new scaffold and the results provide insights into further development of anticancer agents. COA of Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Rathnakar, B; Kumar, GS; Mahammad, SP; Gattu, S; Kalyani, S; Nimma, R; Satyanarayana, M or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Huang, RJ; Wang, YX; Liu, XX; Zhou, P; Jin, SW; Zhang, ZH in [Huang, Renjie; Wang, Yanxin; Liu, XiXi; Zhou, Peng; Jin, Shiwei; Zhang, Zehui] South Cent Univ Nationalities, Key Lab Catalysis & Mat Sci, Minist Educ, Wuhan 430074, Peoples R China published Co-N-x catalyst: an effective catalyst for the transformation of nitro compounds into azo compounds in 2021.0, Cited 24.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The selective hydrogenation of nitro compounds into their corresponding azo compounds is challenging in organic synthesis. In this study, we have developed a facile and efficient catalytic system for the transformation of nitro compounds into azo compounds under mild conditions over a heterogeneous cobalt catalyst (Co-N-x/C-800-AT). The Co-N-x/C-800-AT catalyst was found to be highly active for the reductive-coupling of nitro compounds into azo compounds in ethanol at 110 degrees C and 2.5 bar H-2 pressure with the addition of NaOH as an additive, affording structurally-diverse azo compounds with satisfactory yields (70.4-98.3%). The developed method demonstrated several advantages such as high catalytic activity and high selectivity with tolerance to other functional groups and high stability.

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Huang, RJ; Wang, YX; Liu, XX; Zhou, P; Jin, SW; Zhang, ZH or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. I found the field of Pharmacology & Pharmacy very interesting. Saw the article Design, synthesis, and biological evaluation of chalcone-linked thiazole-imidazopyridine derivatives as anticancer agents published in 2020.0, Reprint Addresses Rao, KRM (corresponding author), Deemed Be Univ, Dept Chem, GITAM Inst Sci Gandhi Inst Technol & Management, Visakhapatnam 530045, Andhra Pradesh, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

A novel library of chalcone linked thiazole-imidazopyridine (12a-j) derivatives were designed, synthesized, and their structures were characterized by(1)H NMR,C-13 NMR and mass spectral studies. Further, all compounds were tested for their anticancer effects on four human cancer cell lines including MCF-7 (breast carcinoma), A549 (lung carcinoma), DU-145 (prostate carcinoma) and MDA MB-231 (breast carcinoma) by employing MTT method, using etoposide as the positive control. Among them, compound12bdisplayed more potent anticancer activity against four cancer cell lines when compared to the positive control.

Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Suma, VR; Sreenivasulu, R; Rao, MVB; Subramanyam, M; Ahsan, MJ; Alluri, R; Rao, KRM or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Unlocking the catalytic potential of tris(3,4,5-trifluorophenyl)borane with microwave irradiation WOS:000454919600010 published article about ASYMMETRIC HYDROBORATION; IMINE HYDROBORATION; ALKENES; ALKYNES; ISOMERIZATION; PINACOLBORANE; OVENS in [Carden, Jamie L.; Gierlichs, Lukas J.; Wass, Duncan F.; Browne, Duncan L.; Melen, Rebecca L.] Cardiff Univ, Sch Chem, Main Bldg,Pk Pl, Cardiff CF10 3AT, S Glam, Wales; [Wass, Duncan F.] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England in 2019.0, Cited 35.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

The catalytic activity of tris(3,4,5-trifluorophenyl)borane has been explored in the 1,2-hydroboration reactions of unsaturated sub-strates. Under conventional conditions, the borane was found to be active only in the hydroboration of aldehyde, ketone and imine substrates, with alkenes and alkynes not being reduced effectively. The use of microwave irradiation on the other hand has permitted alkenes and alkynes to be hydroborated in good yields.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Carden, JL; Gierlichs, LJ; Wass, DF; Browne, DL; Melen, RL or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Cu-Catalyzed one-pot synthesis of thiochromeno-quinolinone and thiochromeno-thioflavone via oxidative double hetero Michael addition using in situ generated nucleophiles WOS:000555234200022 published article about FACILE SYNTHESIS; 4-QUINOLONES; CYCLIZATION; ANNULATION; INHIBITORS; DESIGN; WATER in [Sundaravelu, Nallappan; Sekar, Govindasamy] Indian Inst Technol Madras, Dept Chem, Chennai 600036, Tamil Nadu, India in 2020.0, Cited 41.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

A copper catalyzed three-component synthesis of pi-conjugated tetracyclic thiochromeno-quinolinone and thiochromeno-thioflavone was establishedviaoxidative double hetero Michael addition usingin situgenerated nucleophiles. Xanthate plays a dual role as an odourless sulfur source and a chemoselective reducing agent. Thein situformed iodine plays a crucial role in the oxidation step.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sundaravelu, N; Sekar, G or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article 2-Thiopyrimidine/chalcone hybrids: design, synthesis, ADMET prediction, and anticancer evaluation as STAT3/STAT5a inhibitors WOS:000521276700001 published article about OVERCOME DRUG-RESISTANCE; CHALCONE DERIVATIVES; MOLECULAR TARGETS; LEUKEMIA; CANCER; STAT3; APOPTOSIS; POTENT; DOMAIN; SRC in [Lamie, Phoebe F.; Philoppes, John N.] Beni Suef Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Bani Suwayf 62514, Egypt in 2020.0, Cited 50.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. COA of Formula: C8H7NO3

A novel 2-thiopyrimidine/chalcone hybrid was designed, synthesised, and evaluated for their cytotoxic activities against three different cell lines, K-562, MCF-7, and HT-29. The most active cytotoxic derivatives were 9d, 9f, 9n, and 9p (IC50=0.77-1.74 mu M, against K-562 cell line), 9a and 9r (IC50=1.37-3.56 mu M against MCF-7 cell line), and 9a, 9l, and 9n (IC50=2.10 and 2.37 mu M against HT-29 cell line). Compounds 9a, 9d, 9f, 9n, and 9r were further evaluated for their cytotoxicity against normal fibroblast cell line WI38. Moreover, STAT3 and STAT5a inhibitory activities were determined for the most active derivatives 9a, 9d, 9f, 9n, and 9r. Dual inhibitory activity was observed in compound 9n (IC50=113.31 and 50.75 mu M, against STAT3 and STAT5a, respectively). Prediction of physicochemical properties, drug likeness score, pharmacokinetic and toxic properties was detected.

Welcome to talk about 100-19-6, If you have any questions, you can contact Lamie, PF; Philoppes, JN or send Email.. COA of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Coverage of Haemophilus influenzae Type b Conjugate Vaccine for Children in Mainland China Systematic Review and Meta-analysis WOS:000459304300011 published article about CHILDHOOD IMMUNIZATION; DISEASE; PREVALENCE; PNEUMONIA; SCHEDULES; PROGRAM; BURDEN in [Yang, Ya; Yang, Yu; Zhou, Yibiao; Jiang, Qingwu] Fudan Univ, Key Lab Publ Hlth Safety, Minist Educ China, Shanghai, Peoples R China; [Yang, Ya; Yang, Yu; Zhou, Yibiao; Jiang, Qingwu] Fudan Univ, Trop Dis Res Ctr, Dept Epidemiol, Sch Publ Hlth, Shanghai, Peoples R China; [Scherpbier, Robert W.; Zhu, Xu] UNICEF Beijing Off, Beijing, Peoples R China; [Chen, Yue] Univ Ottawa, Fac Med, Sch Epidemiol & Publ Hlth, Ottawa, ON, Canada in 2019.0, Cited 59.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. HPLC of Formula: C8H7NO3

Background: Use of Haemophilus influenzae type b conjugate vaccine is effective in reducing the disease burden, but its coverage in China is unclear. The aim of this meta-analysis is to assess the coverage of Hib conjugate vaccines in children in Mainland China. Methods: We systematically searched Pubmed, Web of Science, Medline, CNKI and Wanfang to identify studies assessing the coverage of Hib vaccine in Chinese children. Random-effects models were used to obtain pooled estimates for Hib vaccine coverage and analyzed heterogeneity with meta-regression and subgroup analyses. Results: Thirty-three studies that included 7,227,480 subjects in 12 provinces met our inclusion criteria. The pooled overall coverage of Hib conjugate vaccine was 54.9% [95% confidence interval (CI): 52.9-57.0]. The pooled coverage for the nonlocal population (54.3%; 95% CI: 52.4-56.3) was lower than that for the local residents (62.0%; 95% CI: 58.4-65.6). The region-pooled coverage was higher in the east of China (59.7%; 95% CI: 57.3-62.1) than in the central and west parts of the country (48.5%; 95% CI: 40.6-56.4). Overall, 26.7% (95% CI: 20.1-33.2) had 1 dose only, 14.8% (95% CI: 10.0-19.6%) had 2 doses, 13.5% (95% CI: 9.1-17.8) had 3 doses and 14.3% (95% CI: 9.7-18.9) had 4 doses. Conclusions: We found a low coverage of Hib conjugate vaccine, particularly for the nonlocal children and those living in the central and west parts of China. Including Hib vaccine into the national immunization program is recommended to reduce disparities in vaccination coverage.

Welcome to talk about 100-19-6, If you have any questions, you can contact Yang, Y; Yang, Y; Scherpbier, RW; Zhu, X; Chen, Y; Zhou, YB; Jiang, QW or send Email.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 1-(4-Nitrophenyl)ethanone. Recently I am researching about 2-PHOTON ABSORPTION; OPTICAL PROPERTIES; MOLECULES; DESIGN; FLUORESCENCE; EXCITATION, Saw an article supported by the DST, INSPIRE Fellowship New Delhi, Government of India. Published in ELSEVIER in AMSTERDAM ,Authors: Saha, A; Singh, A; Chari, R; Jayabalan, J. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Using green chemical method a series of fifteen systematically substituted 3-(9-substituted anthracen-10-yl)-1-(4-phenyl substituted)prop-2-en-1-one derivatives having high nonlinear absorption coefficient have been synthesized. The nonlinear absorption properties of these compounds were studied using nanosecond pulses at 532 nm wavelength. All 15 derivatives are found to show high nonlinear absorption in the range of 35-640 cm/GW. Among these the derivatives with-NO2 as one of the substitution group show higher nonlinear absorption. The origin of high nonlinear absorption with low linear absorption in the compounds has been attributed to two-step two-photon absorption process. We have shown that the energy bands of these compounds are distributed such that for excitation at 532 nm they have strong nonlinear absorption. These properties of the reported compounds make them a potential candidate for biological imaging and other applications which are based on nonlinear absorption. (C) 2020 Elsevier B.V. All rights reserved.

Welcome to talk about 100-19-6, If you have any questions, you can contact Saha, A; Singh, A; Chari, R; Jayabalan, J or send Email.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 J PHYS CHEM B published article about RADICAL-INDUCED DECARBOXYLATION; ONE-ELECTRON OXIDATION; S-THEREFORE-N; HYDROXYL RADICALS; PROTON-TRANSFER; AQUEOUS-SOLUTION; GLUTAMIC-ACID; FAST EVENTS; VIBRATIONAL SPECTROSCOPY; MECHANISMS RELEVANT in [Filipiak, Piotr; Marciniak, Bronislaw] Adam Mickiewicz Univ, Fac Chem, PL-61614 Poznan, Poland; [Filipiak, Piotr; Marciniak, Bronislaw] Adam Mickiewicz Univ, Ctr Adv Technol, PL-61614 Poznan, Poland; [Bobrowski, Krzysztof] Inst Nucl Chem & Technol, PL-03195 Warsaw, Poland; [Bobrowski, Krzysztof; Hug, Gordon L.] Univ Notre Dame, Radiat Lab, Notre Dame, IN 46556 USA; [Schoneich, Christian] Univ Kansas, Dept Pharmaceut Chem, Sch Pharm, Lawrence, KS 66047 USA in 2020.0, Cited 80.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

The kinetics of intramolecular-contact formation between remote functional groups in peptides with restricted conformational flexibility were examined using designed peptides with variable-length proline bridges. As probes for this motion, free radicals were produced using the center dot OH-induced oxidation at the C-terminal methionine residue of gamma-Glu-(Pro)(n)-Met peptides (n = 0-3). The progress of the radicals’ motion along the proline bridges was monitored as the radicals underwent reactions along the peptides’ backbones. Of particular interest was the reaction between the sulfur atom located in the side chain of the oxidized Met residue and the unprotonated amino group of the glutamic acid moiety. Interactions between them were probed by the radiation-chemical yields (expressed as G values) of the formation of C-centered, alpha-aminoalkyl radicals (alpha N) on the Glu residue. These radicals were monitored directly or via their reaction with p-nitroacetophenone (PNAP) to generate the optically detected PNAP(center dot-) radical anions. The yields of these alpha N radicals were found to be linearly dependent on the number of Pro residues. A constant decrease by 0.09 mu M J(-1) per spacing Pro residue of the radiation-chemical yields of G(alpha N) was observed. Previous reports support the conclusion that the alpha N radicals in these cases would have to result from (S.*.N)(+)-bonded cyclic radical cations that arose as a result from direct contact between the ends of the peptides. Furthermore, by analogy with the rate constants for the formation of intramolecularly (S.*.S)(+)-bonded radical cations in Met-(Pro)-Met peptides (J. Phys. Chem. B 2016, 120, 9732), the rate constants for the formation of intramolecularly (S.*.N)(+)-bonded radical cations are activated to the same extent for all of the gamma-Glu-(Pro)(n)-Met peptides. Thus, the continuous decrease of G(alpha N) with the number of Pro residues (from 0 to 3) suggests that the formation of a contact between the S-atom in the C-terminal Met residue and the N-atom of a deprotonated N-terminal amino group of Glu is controlled in peptides with 0 to 3 Pro residues by the relative diffusion of the S center dot+ and unoxidized N-atom. The overall rate constants of cyclization to form the (S.*.N)-bonded radical cations were estimated to be 3.8 X 10(6) , 1.8 x 10(6) , and 8.1 x 10(5) s(-1) for peptides with n = 0, 1, and 2 Pro residues, respectively. If activation is the same for all of the peptides, then these rate constants are a direct indication for the end-to-end dynamics along the chain.

Product Details of 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Filipiak, P; Bobrowski, K; Hug, GL; Schoneich, C; Marciniak, B or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem