Category: 100-19-6

In 2019.0 ACS OMEGA published article about ONE-POT SYNTHESIS; ENANTIOSELECTIVE HYDROGENATION; HYDROXY ACETALS; CYANOSILYLATION; REARRANGEMENT; CONVERSION; REDUCTION; EFFICIENT in [Shangpliang, O. Risuklang; Wanniang, Kmendashisha; Kshiar, Baskhemlang; Marpna, Ibakyntiew D.; Lipon, Tyrchain Mitre; Myrboh, Bekington] North Eastern Hill Univ, Dept Chem, Ctr Adv Studies Chem, Shillong 793022, Meghalaya, India; [Mizar, Pushpak] Univ Southampton, Southampton SO17 1BJ, Hants, England in 2019.0, Cited 28.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

A novel approach has been developed for the synthesis of a wide range of alpha-ketoacetals by the reaction of alkyl/aryl methyl ketones and aliphatic alcohols in the presence of selenium dioxide catalyzed by p-toluenesufonic acid. This method represents a general route to obtain a wide variety of alpha-ketoacetals in a simple, rapid, and practical manner. This approach is particularly attractive because of the easy availability of the starting materials, mild reaction temperature, and good yields of the products. The resulting alpha-ketoacetals are of much synthetic value as organic intermediates.

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Shangpliang, OR; Wanniang, K; Kshiar, B; Marpna, ID; Lipon, TM; Mizar, P; Myrboh, B or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Nitrate promoted mild and versatile Pd-catalysed C(sp(2))-H oxidation with carboxylic acids WOS:000565016900018 published article about C-H; DIRECT ACYLOXYLATION; BENZOXYLATION; BONDS; ACTIVATION; ARYL; NOX in [Xiong, Xue; Mao, Yang-Jie; Hao, Hong-Yan; He, Yu-Ting; Xu, Zhen-Yuan; Lou, Shao-Jie; Xu, Dan-Qian] Zhejiang Univ Technol, Coll Chem Engn, Key Lab Green Pesticides & Cleaner Prod Technol Z, Catalyt Hydrogenat Res Ctr,State Key Lab Breeding, Hangzhou 310014, Peoples R China; [Luo, Gen] Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Peoples R China in 2020, Cited 30. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

A nitrate-promoted Pd-catalysed mild cross-dehydrogenative C(sp(2))-H bond oxidation of oximes or azobenzenes with diverse carboxylic acids has been developed. In contrast to the previous catalytic systems, this protocol features mild conditions (close to room temperature for most cases) and a broad substrate scope (up to 64 examples), thus constituting a versatile method to directly prepare diverseO-aryl esters. Moreover, the superiority of the nitrate additive in this mild transformation was further determined by experimental and computational evidence.

Welcome to talk about 100-19-6, If you have any questions, you can contact Xiong, X; Mao, YJ; Hao, HY; He, YT; Xu, ZY; Luo, G; Lou, SJ; Xu, DQ or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about PAIR CHEMISTRY; C-H; TRIS(PENTAFLUOROPHENYL)BORANE; DISSOCIATION; ACTIVATION; CARBONYL, Saw an article supported by the Department Chemie; Fonds der Chemischen Industrie for a Kekule fellowship; Projekt DEAL. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Mayer, RJ; Hampel, N; Ofial, AR. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Safety of 1-(4-Nitrophenyl)ethanone

A quantitative Lewis acidity/basicity scale toward boron-centered Lewis acids has been developed based on a set of 90 experimental equilibrium constants for the reactions of triarylboranes with various O-, N-, S-, and P-centered Lewis bases in dichloromethane at 20 degrees C. Analysis with the linear free energy relationship log K-B=LA(B)+LBB allows equilibrium constants, K-B, to be calculated for any type of borane/Lewis base combination through the sum of two descriptors, one for Lewis acidity (LA(B)) and one for Lewis basicity (LBB). The resulting Lewis acidity/basicity scale is independent of fixed reference acids/bases and valid for various types of trivalent boron-centered Lewis acids. It is demonstrated that the newly developed Lewis acidity/basicity scale is easily extendable through linear relationships with quantum-chemically calculated or common physical-organic descriptors and known thermodynamic data (Delta HBF3 ). Furthermore, this experimental platform can be utilized for the rational development of borane-catalyzed reactions.

Safety of 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation WOS:000459510800014 published article about MYCOBACTERIUM-TUBERCULOSIS; RESISTANT TUBERCULOSIS; BIOLOGICAL EVALUATION; HYDRAZIDE-HYDRAZONES; DRUGS; DESIGN; TB; DISEASE; TRENDS in [Beteck, Richard M.; Khanye, Setshaba D.] Rhodes Univ, Dept Chem, Fac Sci, ZA-6140 Grahamstown, South Africa; [Seldon, Ronnett] Univ Cape Town, Dept Chem, Drug Discovery & Dev Ctr H3 D, ZA-7701 Rondebosch, South Africa; [Jordaan, Audrey; Warner, Digby F.] Univ Cape Town, Dept Pathol, SAMRC NHLS UCT Mol Mycobacteriol Res Unit, ZA-7925 Observatory, South Africa; [Warner, Digby F.] Univ Cape Town, Inst Infect Dis & Mol Med, ZA-7952 Observatory, South Africa; [Warner, Digby F.] Univ Cape Town, Wellcome Ctr Clin Infect Dis Res Africa, ZA-7925 Observatory, South Africa; [Hoppe, Heinrich C.] Rhodes Univ, Dept Biochem & Microbiol, Fac Sci, ZA-6140 Grahamstown, South Africa; [Hoppe, Heinrich C.; Laming, Dustin; Khanye, Setshaba D.] Rhodes Univ, Ctr Chem & Biomed Res, ZA-6140 Grahamstown, South Africa; [Legoabe, Lesetja J.] North West Univ, Ctr Excellence Pharmaceut Sci, ZA-2520 Potchefstroom, South Africa; [Khanye, Setshaba D.] Rhodes Univ, Fac Pharm, ZA-6140 Grahamstown, South Africa in 2019.0, Cited 41.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

Herein, we propose novel quinolones incorporating an INH moiety as potential drug templates against TB. The quinolone-based compounds bearing an INH moiety attached via a hydrazide-hydrazone bond were synthesised and evaluated against Mycobacterium tuberculosis H37Rv (MTB). The compounds were also evaluated for cytotoxicity against HeLa cell lines. These compounds showed significant activity (MIC90) against MTB in the range of 0.2-8 mu M without any cytotoxic effects. Compounds 10 (MIC90; 0.9 mu M), 11 (MIC90; 0.2 mu M), 12 (MIC90; 0.8 mu M) and compound 15 (MIC90; 0.8 mu M), the most active compounds in this series, demonstrate activities on par with INH and superior to those reported for the fluoroquinolones. The SAR analysis suggests that the nature of substituents at positions -1 and -3 of the quinolone nucleus influences anti-MTB activity. Aqueous solubility evaluation and in vitro metabolic stability of compound 12 highlights favourable drug-like properties for this compound class.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Beteck, RM; Seldon, R; Jordaan, A; Warner, DF; Hoppe, HC; Laming, D; Legoabe, LJ; Khanye, SD or concate me.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Syntheses and evaluation of new Quinoline derivatives for inhibition of hnRNP K in regulating oncogene c-myc transcription published in 2019, Reprint Addresses Li, D (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci, 132 Waihuan East Rd, Guangzhou 510006, Guangdong, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

Aberrant overexpression of heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a key feature in oncogenesis and progression of many human cancers. hnRNP K has been found to be a transcriptional activator to up-regulate c-myc gene transcription, a critical proto-oncogene for regulation of cell growth and differentiation. Therefore, down-regulation of c-myc transcription by inhibiting hnRNP K through disrupting its binding to c-myc gene promoter is a potential approach for cancer therapy. In the present study, we synthesized and screened a series of Quinoline derivatives and evaluated their binding affinity for hnRNP K. Among these derivatives, (E)-1-(4-methoxyphenyl)-3-(4 morpholino-6-nitroquinolin-2-yl)prop-2-en-1-one (compound 25) was determined to be the first-reported hnRNP K binding ligand with its K-D values of 4.6 and 2.6 mu M measured with SPR and MST, respectively. Subsequent evaluation showed that the binding of compound 25 to hnRNP K could disrupt its unfolding of c-myc promoter i-motif, resulting in down-regulation of c-myc transcription. Compound 25 showed a selective anti-proliferative effect on human cancer cell lines with IC50, values ranged from 1.36 to 3.59 mu M. Compound 25 exhibited good tumor growth inhibition in a Hela xenograft tumor model, which might be related to its binding with hnRNP K. These findings illustrated that inhibition of DNA-binding protein hnRNP K by compound 25 could be a new and selective strategy of regulating oncogene transcription instead of targeting promoter DNA secondary structures such as G-quadruplexes or i-motifs.

Welcome to talk about 100-19-6, If you have any questions, you can contact Shu, B; Zeng, P; Kang, SS; Li, PH; Hu, DX; Kuang, GT; Cao, JJ; Li, XY; Zhang, ML; An, LK; Huang, ZS; Li, D or send Email.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 APPL CATAL B-ENVIRON published article about CRYSTALLINE; OXIDATION; EFFICIENT; STORAGE; LUMINESCENT; STABILITY; SULFIDES; HYDROGEN in [Lopez-Magano, Alberto; Platero-Prats, Ana E.; Cabrera, Silvia; Mas-Balleste, Ruben] Univ Autonoma Madrid, Inorgan Chem Dept, Modulo 7, Madrid 28049, Spain; [Platero-Prats, Ana E.] Univ Autonoma Madrid, Condensed Matter Phys Ctr IFIMAC, Campus Cantoblanco, Madrid 28049, Spain; [Cabrera, Silvia; Mas-Balleste, Ruben; Aleman, Jose] Univ Autonoma Madrid, Inst Adv Res Chem Sci IAdChem, Madrid 28049, Spain; [Aleman, Jose] Univ Autonoma Madrid, Organ Chem Dept, Madrid 28049, Spain in 2020.0, Cited 55.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

A new photoactive Pt (II) hydroxyquinoline complex has been covalently linked into the structure of an iminebased layered covalent organic framework (COF) through the monomer truncation strategy. Such strategy allows the incorporation of molecular fragments with only one functional group able to condensate into the imine-framework. The photocatalytic activity of the resulting Pt@COF has been applied to the oxidation of sulfides to sulfoxides, obtaining excellent results for all the studied cases, and showing that this reaction goes through both photoredox and energy transfer processes. The results obtained showed a great enhancement of the catalytic activity (up to 25,000 turnover number, TON), stability and a significant decrease on the reaction times, as a consequence of immobilization and isolation of Pt(II) centers into the organic framework. In addition, Pt@COF has been proved to be an excellent heterogeneous photocatalyst also in exclusive photoredox processes, reaching 7500 TON in hydrodebromination reactions.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Lopez-Magano, A; Platero-Prats, AE; Cabrera, S; Mas-Balleste, R; Aleman, J or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. Recently I am researching about ONE-POT SYNTHESIS; TRISODIUM CITRATE DIHYDRATE; MULTICOMPONENT REACTION; PHARMACEUTICAL-INDUSTRY; GABA(A) RECEPTOR; GREEN CHEMISTRY; EASY ACCESS; DERIVATIVES; EFFICIENT; ZOLPIDEM, Saw an article supported by the DST, New DelhiDepartment of Science & Technology (India); UGC, New DelhiUniversity Grants Commission, India. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Brahmachari, G; Nayek, N; Karmakar, I; Nurjamal, K; Chandra, SK; Bhowmick, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A water-mediated and catalyst-free practical method for the synthesis of a new series of pharmaceutically interesting functionalized 5-(2-arylimidazo[1,2-a]pyridin-3-yl)pyrimidine-2,4-(1H,3H)-diones has been accomplished based on a one-pot multicomponent reaction between arylglyoxal monohydrates, 2-aminopyridines/2-aminopyrimidine, and barbituric/N,N-dimethylbarbituric acids under reflux conditions. The salient features of this protocol are avoidance of any additive/catalyst and toxic organic solvents, use of water as reaction medium, clean reaction profiles, operational simplicity, ease of product isolation/purification without the aid of tedious column chromatography, good to excellent yields, and high atom-economy and low E-factor.

Welcome to talk about 100-19-6, If you have any questions, you can contact Brahmachari, G; Nayek, N; Karmakar, I; Nurjamal, K; Chandra, SK; Bhowmick, A or send Email.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. In 2019 CHEMISTRYSELECT published article about ONE-POT SYNTHESIS; HIGHLY EFFICIENT; BENZYL ALCOHOLS; METHYL KETONES; BENZIMIDAZOLES; QUINAZOLINONES; BENZOXAZOLES; AMINATION; IODINE; FACILE in [Khan, Danish; Ahmed, Naseem] Indian Inst Technol Roorkee, Dept Chem, Roorkee 247667, Uttarakhand, India; [Alsharif, Meshari A.; Alahmdi, Mohammed Issa; Mukhtar, Sayeed] Univ Tabuk, Fac Sci, Dept Chem, Tabuk 71491, Saudi Arabia in 2019, Cited 66. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

An interestingcyclization reactions of aryl ketones with 2-amino aniline derivatives under SeO2 (oxidant) are described for the synthesis of benzoxazole, benzothiazole, benzimidazole and quinazolinone through the C-C cleavage of acetophenone. The reaction likely involves sequential C-N, C-O and C-S bond formation followed by C(CO)-C(alkyl) bond cleavage. Various substituted fused heterocycles are obtained in good to excellent (gram scale) yields in a single step from readily available acetophenones.

Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Khan, D; Ahmed, N; Alsharif, MA; Alahmdi, MI; Mukhtar, S or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Convenient synthesis of 4,5-unsubstituted 3-aroylisoxazoles from methyl aryl ketones and (vinylsulfonyl)benzene in water WOS:000610242900013 published article about ONE-POT SYNTHESIS; C-H ARYLATION; COPPER(I)-CATALYZED SYNTHESIS; ISOXAZOLES; CYCLOADDITION; CYCLIZATION; COUPLINGS; EFFICIENT; ALKYNES; CHLOROFORM in [Wang, Liang; Tao, Yu; Zhang, Nana; Li, Shubai] Changzhou Vocat Inst Engn, Sch Chem & Pharmaceut Engn, Changzhou 213164, Peoples R China in 2021.0, Cited 58.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

A convenient synthesis of 3-aroylisoxazoles from methyl ketones and (vinylsulfonyl)benzene in 2%TPGS-750-M/H2O has been developed. This reaction proceeds via tandem tert-butyl nitrite-promoted Csp(3)-H functionalization of methyl ketones, 1,3-dipolar cycloaddition and base-catalyzed aromatization, providing the corresponding products in moderate to good yields. (C) 2020 Elsevier Ltd. All rights reserved.

Recommanded Product: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Synthesis of cis-1,2-diol-type chiral ligands and their dioxaborinane derivatives: Application for the asymmetric transfer hydrogenation of various ketones and biological evaluation published in 2020.0. Formula: C8H7NO3, Reprint Addresses Kilic, A (corresponding author), Harran Univ, Chem Dept, TR-63190 Sanliurfa, Turkey.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Two cis-1,2-diol-type chiral ligands (T-1 and T-2) and their tri-coordinated chiral dioxaborinane (T(1-2)B(1-2)) and four-coordinated chiral dioxaborinane adducts with 4-tert-butyl pyridine sustained by N -> B dative bonds (T(1-2)B(1-2)-N) were synthesized and characterized by various spectroscopic techniques such as NMR (H-1, C-13, and B-11), FT-IR and UV-Vis spectroscopy, LC-MS/MS, and elemental analysis. It was suggested that both ferrocene and trifluoromethyl groups played key roles in the catalytic and biological studies because they could tune the solubility of the chiral dioxaborinane complexes and adjust the strength of intermolecular interactions. To assess the biological activities of newly synthesized chiral dioxaborinane compounds, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging, reducing power, antibacterial, DNA binding, and DNA cleavage activities were tested. Then, all chiral dioxaborinane complexes were investigated as catalysts for the asymmetric transfer hydrogenation of various ketones under suitable conditions. The results indicated that the chiral dioxaborinane catalysts performed well with high yields.

Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Kilic, A; Balci, TE; Arslan, N; Aydemir, M; Durap, F; Okumu, V; Tekin, R or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem