Category: 100-19-6

Safety of 1-(4-Nitrophenyl)ethanone. Recently I am researching about ELECTROLUMINESCENCE PROPERTIES; ENERGY-TRANSFER; SINGLE-POLYMER; QUANTUM DOTS; SOLID-STATE; EMISSION; BLUE; EFFICIENT; DIODES; FLUORESCENCE, Saw an article supported by the Department of Atomic Energy (DAE-SRC) India [21/13/2015BRNS/35029]; CSIRCouncil of Scientific & Industrial Research (CSIR) – India; UGC, New DelhiUniversity Grants Commission, India. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Sharma, CP; Gupta, NM; Singh, J; Yadav, RAK; Dubey, DK; Rawat, KS; Jha, AK; Jou, JH; Goel, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A series of donor-acceptor pyranones (3a-m, 4a-h) were synthesized using alpha-oxo-ketene-S,S-acetal as the synthon for their application as emissive materials for energy-saving organic light-emitting devices (OLEDs). Among them, five pyranones 3f, 3g, 3h, 3m, and 4e exhibited highly bright fluorescence in the solid state and weak or no emission in the solution state. Photophysical analysis of these dyes revealed that only 3f and 3m showed aggregation-induced emission behavior in a THF/water mixture (0-99%) with varying water fractions (f(w)) leading to bright fluorescence covering the entire visible region, while other derivatives 3g, 3h, and 4e did not show any fluorescence signal. The computational studies of the compounds revealed that the longer wavelength absorption originates from HOMO to LUMO electronic excitation. These dyes exhibited good thermal stability with 5% weight loss temperature in the range of 218-347 degrees C. The potential application of the donor-acceptor pyranone dyads was demonstrated by fabrication of solution-processed OLEDs. Remarkably, OLED devices prepared using highly emissive compounds 6-(anthracen-9-yl)-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile (3m) and 6-(4-methoxyphenyl)-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile (3f) displayed pure white emission with CIE coordinates of (0.29, 0.31) and (0.32, 0.32), respectively. Additionally, the resultant devices exhibited external quantum efficiencies of 1.9 and 1.2% at 100 cd m(-2), respectively.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sharma, CP; Gupta, NM; Singh, J; Yadav, RAK; Dubey, DK; Rawat, KS; Jha, AK; Jou, JH; Goel, A or concate me.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. Zhang, GJ; Tang, FY; Wang, XY; An, P; Wang, LQ; Liu, YN in [Zhang, Guangji; Tang, Feiying; An, Ping; Wang, Liqiang; Liu, You-Nian] Cent South Univ, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China; [Zhang, Guangji; Wang, Liqiang; Liu, You-Nian] Cent South Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China; [Wang, Xiaoying] Qilu Univ Technol, State Key Lab Biobased Mat & Green Papermaking, Jinan 250353, Shandong, Peoples R China published Co,N-Codoped Porous Carbon-Supported CoyZnS with Superior Activity for Nitroarene Hydrogenation in 2020.0, Cited 55.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

It is a persistent target to develop noble-metal-free catalysts that can achieve chemoselective hydrogenation of nitro compounds under mild reaction conditions. In this work, we report a new strategy for preparation of hydrogenation catalysts containing both CoNx and CoyZnS supported on N-doped porous carbon (CoNx-CoyZnS@NPC-Z). The CoNx-CoyZnS@NPC-Z catalysts were prepared by pyrolyzing the protein-metal-ion networks, followed by treatment with acid. We found that CoNxCoyZnS@NPC-3 catalyst delivers high catalytic activity and selectivity, affording almost full conversion and >98% selectivity in water/methanol mixture solvents at 90 degrees C under 5 bar of H-2 pressure for 3 h of reaction. Notably, the catalytic hydrogenation can work even under 1 bar of H-2 pressure and at room temperature with high conversion and selectivity. Besides, CoNx-CoyZnS@NPC-3 exhibits remarkable tolerance to CO or H2S poisoning and acid erosion.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, GJ; Tang, FY; Wang, XY; An, P; Wang, LQ; Liu, YN or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Filipiak, P; Bobrowski, K; Hug, GL; Schoneich, C; Marciniak, B in [Filipiak, Piotr; Marciniak, Bronislaw] Adam Mickiewicz Univ, Fac Chem, PL-61614 Poznan, Poland; [Filipiak, Piotr; Marciniak, Bronislaw] Adam Mickiewicz Univ, Ctr Adv Technol, PL-61614 Poznan, Poland; [Bobrowski, Krzysztof] Inst Nucl Chem & Technol, PL-03195 Warsaw, Poland; [Bobrowski, Krzysztof; Hug, Gordon L.] Univ Notre Dame, Radiat Lab, Notre Dame, IN 46556 USA; [Schoneich, Christian] Univ Kansas, Dept Pharmaceut Chem, Sch Pharm, Lawrence, KS 66047 USA published N-Terminal Decarboxylation as a Probe for Intramolecular Contact Formation in gamma-Glu-(Pro)(n)-Met Peptides in 2020.0, Cited 80.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The kinetics of intramolecular-contact formation between remote functional groups in peptides with restricted conformational flexibility were examined using designed peptides with variable-length proline bridges. As probes for this motion, free radicals were produced using the center dot OH-induced oxidation at the C-terminal methionine residue of gamma-Glu-(Pro)(n)-Met peptides (n = 0-3). The progress of the radicals’ motion along the proline bridges was monitored as the radicals underwent reactions along the peptides’ backbones. Of particular interest was the reaction between the sulfur atom located in the side chain of the oxidized Met residue and the unprotonated amino group of the glutamic acid moiety. Interactions between them were probed by the radiation-chemical yields (expressed as G values) of the formation of C-centered, alpha-aminoalkyl radicals (alpha N) on the Glu residue. These radicals were monitored directly or via their reaction with p-nitroacetophenone (PNAP) to generate the optically detected PNAP(center dot-) radical anions. The yields of these alpha N radicals were found to be linearly dependent on the number of Pro residues. A constant decrease by 0.09 mu M J(-1) per spacing Pro residue of the radiation-chemical yields of G(alpha N) was observed. Previous reports support the conclusion that the alpha N radicals in these cases would have to result from (S.*.N)(+)-bonded cyclic radical cations that arose as a result from direct contact between the ends of the peptides. Furthermore, by analogy with the rate constants for the formation of intramolecularly (S.*.S)(+)-bonded radical cations in Met-(Pro)-Met peptides (J. Phys. Chem. B 2016, 120, 9732), the rate constants for the formation of intramolecularly (S.*.N)(+)-bonded radical cations are activated to the same extent for all of the gamma-Glu-(Pro)(n)-Met peptides. Thus, the continuous decrease of G(alpha N) with the number of Pro residues (from 0 to 3) suggests that the formation of a contact between the S-atom in the C-terminal Met residue and the N-atom of a deprotonated N-terminal amino group of Glu is controlled in peptides with 0 to 3 Pro residues by the relative diffusion of the S center dot+ and unoxidized N-atom. The overall rate constants of cyclization to form the (S.*.N)-bonded radical cations were estimated to be 3.8 X 10(6) , 1.8 x 10(6) , and 8.1 x 10(5) s(-1) for peptides with n = 0, 1, and 2 Pro residues, respectively. If activation is the same for all of the peptides, then these rate constants are a direct indication for the end-to-end dynamics along the chain.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Filipiak, P; Bobrowski, K; Hug, GL; Schoneich, C; Marciniak, B or concate me.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Metal-Free Synthesis and Photophysical Properties of 1,2,4-Triarylpyrroles published in 2021. Safety of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Huang, HW; Deng, GJ (corresponding author), Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Minist Educ,Key Lab Environm Friendly Chem & Appl, Xiangtan 411105, Peoples R China.; Qin, AJ; Deng, GJ (corresponding author), South China Univ Technol, Guangdong Prov Key Lab Luminescence Mol Aggregate, Guangzhou 510640, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal- free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chang, D; Chen, JJ; Liu, Y; Huang, HW; Qin, AJ; Deng, GJ or concate me.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. In 2020.0 POLYCYCL AROMAT COMP published article about BIOLOGICAL EVALUATION; CYTOTOXIC ACTIVITY; IN-VITRO; ISOXAZOLE; INHIBITION; APOPTOSIS; CURCUMIN; GROWTH in [Saeedi, Mina] Univ Tehran Med Sci, Fac Pharm, Med Plants Res Ctr, Tehran, Iran; [Saeedi, Mina; Karimpour-Razkenari, Elahe; Akbarzadeh, Tahmineh] Univ Tehran Med Sci, Persian Med & Pharm Res Ctr, Tehran, Iran; [Hashemi, Mehdi; Rafinejad, Ali; Akbarzadeh, Tahmineh] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, Tehran, Iran; [Mahdavi, Mohammad] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, Tehran, Iran; [Najafi, Zahra] Hamadan Univ Med Sci, Sch Pharm, Dept Med Chem, Hamadan, Hamadan, Iran; [Mirfazli, Seyedeh Sara] Iran Univ Med Sci, Sch Pharm, Dept Med Chem, Int Campus, Tehran, Iran; [Mohammadian, Razieh; Kabudanian Ardestani, Sussan] Univ Tehran, Inst Biochem & Biophys, Dept Biochem, Tehran, Iran; [Safavi, Maliheh] Iranian Res Org Sci & Technol, Dept Biotechnol, Tehran, Iran in 2020.0, Cited 30.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

In this study, a new series of N-(di or trimethoxyaryl)-5-arylisoxazole-3-carboxamide derivatives were synthesized and evaluated against human breast cancer cell lines including MCF-7, MDA-MB-231, and T-47D. Among the synthesized compounds, 5-(m-tolyl)-N-(3,4,5-trimethoxyphenyl)isoxazole-3-carboxamide (8f) showed significant cytotoxicity against all three cell lines comparing with etoposide as the reference drug. Also, Annexin V-FITC/propidium iodide and acridine orange/ethidium bromide staining assay were performed to validate apoptotic activity of compound 8f. The results confirmed induction of apoptosis at early stage.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Saeedi, M; Hashemi, M; Mahdavi, M; Rafinejad, A; Najafi, Z; Mirfazli, SS; Mohammadian, R; Karimpour-Razkenari, E; Ardestani, SK; Safavi, M; Akbarzadeh, T or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Versatile Glycosyl Sulfonates in beta-Selective C-Glycosylation WOS:000510495500001 published article about BIOLOGICAL ROLES; OLIGOSACCHARIDES; GLUCOPYRANOSYL; KETONES; ACCESS; GALACTOSYLCERAMIDE; CONSTRUCTION; ENHANCEMENT; MECHANISMS; CHEMISTRY in [Ling, Jesse; Bennett, Clay S.] Tufts Univ, 62 Talbot Ave, Medford, MA 02155 USA in 2020.0, Cited 72.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

C-Glycosides are both a common motif in many bioactive natural products and important glycoside mimetics. We demonstrate that activating a hemiacetal with a sulfonyl chloride, followed by treating the resultant glycosyl sulfonate with an enolate results in the stereospecific construction of beta-linked C-glycosides. This reaction tolerates a range of acceptors and donors, including disaccharides. The resulting products can be readily derivatized into C-glycoside analogues of beta-glycoconjugates, including C-disaccharide mimetics.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ling, J; Bennett, CS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 1-(4-Nitrophenyl)ethanone. In 2021.0 STRUCT CHEM published article about ELECTRONIC POPULATION ANALYSIS; MOLECULAR WAVE FUNCTIONS; INDEPENDENT CHEMICAL-SHIFTS; PHYSICAL INTERPRETATION; INTRAMOLECULAR INTERACTIONS; PHYSICOCHEMICAL PROPERTIES; THEORETICAL APPROACH; TEMPERATURE CRYSTAL; HAMMETT CONSTANTS; ORGANIC-COMPOUNDS in [Jezuita, Anna; Ejsmont, Krzysztof] Opole Univ, Fac Chem, Oleska 48, PL-45052 Opole, Poland; [Jezuita, Anna] Jan Dlugosz Univ Czestochowa, Fac Sci & Technol, Armii Krajowej 13-15, PL-42200 Czestochowa, Poland; [Szatylowicz, Halina] Warsaw Univ Technol, Fac Chem, Noakowskiego 3, PL-00664 Warsaw, Poland in 2021.0, Cited 126.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Numerous studies on nitro group properties are associated with its high electron-withdrawing ability, by means of both resonance and inductive effect. The substituent effect of the nitro group may be well described using either traditional substituent constants or characteristics based on quantum chemistry, i.e., cSAR, SESE, and pEDA/sEDA models. Interestingly, the cSAR descriptor allows to describe the electron-attracting properties of the nitro group regardless of the position and the type of system. Analysis of classical and reverse substituent effects of the nitro group in various systems indicates strongpi-electron interactions with electron-donating substituents due to the resonance effect. This significantly affects thepi-electron delocalization of the aromatic ring decreasing the aromatic character, evidenced clearly by HOMA values. Use of the pEDA/sEDA model allows to measure the population of electrons transferred from the ring to the nitro group.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Jezuita, A; Ejsmont, K; Szatylowicz, H or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. In 2021.0 J AM CHEM SOC published article about C-H BONDS; CHEMISTRY in [Pinkert, Tobias; Das, Mowpriya; Schrader, Malte L.; Glorius, Frank] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany in 2021.0, Cited 90.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Herein, we describe the formation of quaternary carbon centers with excellent diastereoselectivity via a strain-release protocol. An organometallic species is generated by Cp*Rh(III)-catalyzed C-H activation, which is then coupled with strained bicyclobutanes (BCBs) and a prochiral carbon electrophile in a three-component reaction. This work illustrates a rare example of BCBs in transition metal catalysis and demonstrates their broad potential to access novel reaction pathways. The method developed exhibits ample functional group tolerance, and the products can be further transformed into valuable alpha-quaternary beta-lactones. Preliminary mechanistic investigations suggest a twofold C-C bond cleavage sequence involving sigma-bond insertion and an ensuing beta-carbon elimination event.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Pinkert, T; Das, M; Schrader, ML; Glorius, F or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. Authors Wittmann, S; Martzel, T; Truong, CTP; Toffano, M; Oudeyer, S; Guillot, R; Bournaud, C; Gandon, V; Briere, JF; Vo-Thanh, G in WILEY-V C H VERLAG GMBH published article about in [Wittmann, Stephane; Pham Truong, Cong Thanh; Toffano, Martial; Guillot, Regis; Bournaud, Chloee; Gandon, Vincent; Vo-Thanh, Giang] Univ Paris Saclay, CNRS, UMR 8182, Inst Chim Mol & Mat Orsay, F-91405 Orsay, France; [Martzel, Thomas; Oudeyer, Sylvain; Briere, Jean-Francois] Normandie Univ, UNIROUEN, INSA Rouen, CNRS,COBRA, F-76000 Rouen, France; [Gandon, Vincent] Ecole Polytech, Inst Polytech Paris, Lab Chim Mol LCM, CNRS,UMR 9168, Route Saclay, F-91128 Palaiseau, France in 2021.0, Cited 39.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Upon Bronsted base organocatalysis, ketone-derived alkylidene Meldrum’s acids proved to be competent vinylogous platforms able to undergo a formal (4+2) cycloaddition reaction with dihydro-2,3-furandione, providing an unprecedented route to 3,6-dihydropyran-2-ones as spiro[4.5]decane derivatives with up to 98 % ee thanks to the commercially available Takemoto catalyst. Preliminary investigation showed that this reaction could be extended to other activated ketones, establishing these alkylidene Meldrum’s acids as a novel C4-synthon in the vinylogous series.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wittmann, S; Martzel, T; Truong, CTP; Toffano, M; Oudeyer, S; Guillot, R; Bournaud, C; Gandon, V; Briere, JF; Vo-Thanh, G or concate me.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. In 2019.0 MOL DIVERS published article about BENZAMIDE; DISCOVERY; ALPHA; ACIDS in [Nian, Si-Yun; Jiang, Zheng-Li] Taizhou Hosp Zhejiang Prov, Dept Clin Pharm, Xi Men St 150, Linhai 317000, Zhejiang, Peoples R China; [Nian, Si-Yun; Wang, Guo-Ping; Xiao, Ying] China State Inst Pharmaceut Ind, Shanghai Inst Pharmaceut Ind, Shanghai 201203, Peoples R China; [Nian, Si-Yun; Wang, Guo-Ping] Aurisco Pharmaceut Yangzhou Co Ltd, Yangzhou 225100, Jiangsu, Peoples R China; [Huang, Mo-Han; Zhou, Yi-Huan; Tan, Xiang-Duan] Guilin Med Univ, Coll Pharm, Guilin 541004, Peoples R China in 2019.0, Cited 21.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Most of reported steroidal FXR antagonists are restricted due to low potency. We described the design and synthesis of novel nonsteroidal scaffold SIPI-7623 derivatives as FXR antagonists. The most potent compound A-11 (IC50 = 7.8 +/- 1.1 mu M) showed better activity compared to SIPI-7623 (IC50 = 40.8 +/- 1.7 mu M) and guggulsterone (IC50 = 45.9 +/- 1.1 mu M). Docking of A-11 in FXR’s ligand-binding domain was also studied.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Nian, SY; Wang, GP; Jiang, ZL; Xiao, Y; Huang, MH; Zhou, YH; Tan, XD or concate me.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem