Category: 100-19-6

Rastogi, GK; Deka, B; Deb, ML; Baruah, PK in [Rastogi, Gaurav K.; Deka, Bhaskar; Deb, Mohit L.; Baruah, Pranjal K.] Gauhati Univ, GUIST, Dept Appl Sci, Gauhati 781014, Assam, India; [Rastogi, Gaurav K.] NEIST, CSIR, Dept Appl Organ Chem, Jorhat 785006, Assam, India published Diastereoselective sp3-C-H Functionalization of Arylmethyl Ketones and Transformation of E- to Z-Products Through Photocatalysis in 2020.0, Cited 91.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

We have developed an efficient metal-free route for the synthesis of 1,4-enedione derivatives under microwave irradiation by reacting easily available arylmethylketones with DMSO or diphenyl sulfoxide in the presence of TBAI and persulfate. The reaction is very clean and completes within very short time. All the reagents and catalysts are cheap and environmentally benign. In addition, the E-isomer of the products can easily be transformed into the Z-isomer by using eosin Y photocatalyst under the irradiation of white CFL.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Rastogi, GK; Deka, B; Deb, ML; Baruah, PK or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Arif, R; Rana, M; Yasmeen, S; Amaduddin; Khan, MS; Abid, M; Khan, MS; Rahisuddin in [Arif, Rizwan; Rana, Manish; Yasmeen, Shama; Rahisuddin] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India; [Amaduddin; Abid, Mohammad] Jamia Millia Islamia, Dept Biosci, New Delhi 110025, India; [Khan, M. S.] Jamia Millia Islamia, Dept Phys, New Delhi 110025, India; [Khan, Md Shahzad] Galgotias Univ, Sch Basic & Appl Sci, Greater Noida 203201, India published Facile synthesis of chalcone derivatives as antibacterial agents: Synthesis, DNA binding, molecular docking, DFT and antioxidant studies in 2020.0, Cited 63.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A series of beta-chalcones derivatives (1a-11) was synthesized using different substituted amines in basic condition by Claisen-Schmidt condensation reaction. Structural analysis of the synthesized compounds was carried out by various characterization techniques. Antimicrobial properties of the chalcone derivatives (1a-11) were evaluated against different bacterial strains Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica, Staphylococcus pneumoniae and Enterococcus faecalis by disc diffusion method. The pharmacological treatment of chalcones showed that chalcone 1b has promising potential against tested bacterial strains. Ct-DNA was used to study the binding interactions of the potent chalcone derivative 1b by means of absorption spectroscopy, viscosity measurement, fluorescence quenching, cyclic voltammetery and circular dichroism study. Chalcone 1b showed significant binding towards Ct-DNA with intrinsic binding constant (K-b) 1.75 x 10(4)M(-1). Molecular docking study of the target compound was also carried out against B-DNA dodecamer d(CGCGAATTCGCG)(2) and it has been found that chalcone 1b can bind to Ct-DNA via an intercalative mode. For the chalcone derivative 1b and Ct-DNA interaction, static quenching mechanism observed which was further confirmed using time-resolved fluorescence spectroscopy. To optimize the chalcone derivative 1b for HOMO-LUMO energy calculation, Density Functional Theory (DFT) has been used. Time dependent-DFT study has been optimized to generate vertical excitation energies, absorption wavelengths and oscillator strengths of the chalcone derivative lb. Antioxidant activity was also carried out to evaluate the antioxidant nature of the chalcone derivative lb by DPPH and H2O2 assay. (C) 2020 Elsevier B.V. All rights reserved.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Arif, R; Rana, M; Yasmeen, S; Amaduddin; Khan, MS; Abid, M; Khan, MS; Rahisuddin or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about 2 CHK2 INHIBITORS; POTENTIAL ANTICANCER; CARBAZOLES SYNTHESIS; DERIVATIVES; DISCOVERY; SCAFFOLD; BENDAMUSTINE; MOIETY; DRUGS, Saw an article supported by the Indian Council of Medical Research, New Delhi, IndiaIndian Council of Medical Research (ICMR) [58/16/2013BMS]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Sivaramakarthikeyan, R; Shunmugam, I; Vadivel, S; Lim, WM; Mai, CW; Ramalingan, C. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Recommanded Product: 100-19-6

Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a-6j has been obtained from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a hybridpossessing para-nitrophenyl moiety connected to a pyrazole scaffold (6a) exerted the highest anti-inflammatory activity, which is superior to the standard, diclofenac sodium. While executing the 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, a hybrid-possessing para-bromophenyl unit integrated at the pyrazole structural motif (6i) exhibited the highest activity among the hybrids examined. Besides, evaluation of anticancer potency of the synthesized hybrids revealed that the one containing a para-fluorophenyl unit tethered at the pyrazole nucleus (6h) showed the highest activity against both the pancreatic cancer cells (SW1990 and AsPCl) investigated. Considerable binding affinity between B-cell lymphoma and the hybrid, 6h has been reflected while performing molecular docking studies (-8.65 kcal/mol). The outcomes of the investigation expose that these hybrids could be used as effective intermediates to construct more potent biological agents.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sivaramakarthikeyan, R; Shunmugam, I; Vadivel, S; Lim, WM; Mai, CW; Ramalingan, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2021.0 J ORG CHEM published article about DIMETHYL-SULFOXIDE; AMINOOXYGENATION; 2-AMINOPYRIDINES; DERIVATIVES; IMIDAZO; KETONES; ALKYNES; ACCESS in [Zhang, Yi; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Inst Adv Studies, Taizhou 318000, Peoples R China; [Zhang, Yi; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China; [Zhang, Yi; Ma, Yongmin] Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China in 2021.0, Cited 43.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

A convenient one-pot, three-component reaction has been developed for the synthesis of 3-aroylimidazo[1,2-a]-N-hetero-cycles from aryl ketones and 2-amino-N-heterocycles using dimethyl sulfoxide as a methylene donor. The reaction proceeds smoothly catalyzed by I-2 in the presence of K2S2O8 and affords the desired products in moderate to good yields. This protocol offers significant superiority in accessing biologically active 3-aroylimidazo[1,2-a]-N-heterocycles with various substitution patterns.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, Y; Chen, RE; Wang, ZM; Wang, L; Ma, YM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Lesanavicius, M; Aliverti, A; Sarlauskas, J; Cenas, N in MDPI published article about ELECTRON-TRANSFER REACTIONS; CYTOCHROME P450 REDUCTASE; FERREDOXIN-NADP(+) REDUCTASE; SINGLE-ELECTRON; 1,4-DI-N-OXIDE DERIVATIVES; NADPH; QUINONES; FAD; TIRAPAZAMINE; POTENTIALS in [Lesanavicius, Mindaugas; Sarlauskas, Jonas; Cenas, Narimantas] Vilnius Univ, Inst Biochem, Dept Xenobiot Biochem, Sauletekio 7, LT-10257 Vilnius, Lithuania; [Aliverti, Alessandro] Univ Milan, Dept Biosci, Via Celoria 26, I-20133 Milan, Italy in 2020, Cited 49. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Ferredoxin:NADP(+) oxidoreductase from Plasmodium falciparum (PfFNR) catalyzes the NADPH-dependent reduction of ferredoxin (PfFd), which provides redox equivalents for the biosynthesis of isoprenoids and fatty acids in the apicoplast. Like other flavin-dependent electrontransferases, PfFNR is a potential source of free radicals of quinones and other redox cycling compounds. We report here a kinetic study of the reduction of quinones, nitroaromatic compounds and aromatic N-oxides by PfFNR. We show that all these groups of compounds are reduced in a single-electron pathway, their reactivity increasing with the increase in their single-electron reduction midpoint potential (E-7(1)). The reactivity of nitroaromatics is lower than that of quinones and aromatic N-oxides, which is in line with the differences in their electron self-exchange rate constants. Quinone reduction proceeds via a ping-pong mechanism. During the reoxidation of reduced FAD by quinones, the oxidation of FADH(.) to FAD is the possible rate-limiting step. The calculated electron transfer distances in the reaction of PfFNR with various electron acceptors are similar to those of Anabaena FNR, thus demonstrating their similar intrinsic reactivity. Ferredoxin stimulated quinone- and nitro-reductase reactions of PfFNR, evidently providing an additional reduction pathway via reduced PfFd. Based on the available data, PfFNR and possibly PfFd may play a central role in the reductive activation of quinones, nitroaromatics and aromatic N-oxides in P. falciparum, contributing to their antiplasmodial action.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Lesanavicius, M; Aliverti, A; Sarlauskas, J; Cenas, N or concate me.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Copper-Catalyzed [2+2+1+1] Annulation for the Regioselective Synthesis of 2,6-Diarylpyridines via C1-Insertion and Subsequent Cyclization published in 2020.0, Reprint Addresses Malakar, CC (corresponding author), Natl Inst Technol Manipur, Dept Chem, Imphal 795004, Manipur, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

Copper-catalyzed [2+2+1+1] annulation strategy has been investigated for the regioselective synthesis of symmetrical and unsymmetrical 2,6-diarylpyridines using aliphatic amines as nitrogen source and DMSO as C1-synthon. The developed protocol was successful for the transformation of non-activated aromatic ketones and non-activated aliphatic amines into 2,6-diarylpyridinesviaan easy to access approach. This protocol has been verified on wide range of substrates having various functional groups.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Vodnala, N; Gujjarappa, R; Satheesh, V; Gupta, R; Kaldhi, D; Kabi, AK; Malakar, CC or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

COA of Formula: C8H7NO3. Authors Pogaku, V; Krishna, VS; Sriram, D; Rangan, K; Basavoju, S in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Pogaku, Vinay; Basavoju, Srinivas] Natl Inst Technol, Dept Chem, Warangal 506004, Telangana, India; [Krishna, Vagolu Siva; Sriram, Dharmarajan] Birla Inst Technol & Sci Pilani, Dept Pharm, Hyderabad Campus, Hyderabad 500078, Telangana, India; [Rangan, Krishnan] Birla Inst Technol & Sci Pilani, Dept Chem, Hyderabad Campus, Hyderabad 500078, India in 2019.0, Cited 42.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The aim of the study is to design and synthesis of a new series of potent anti-TB 1,2,4-triazol-1-yl-pyrazole based spirooxindolopyrrolizidines with their safety profile. A synergetic effect of ultrasonication and ionic liquid was shown successfully as a green methodology for the synthesis of title compounds 6a-t. These derivatives were obtained in shorter reaction time with good yields and well characterized by various spectroscopic methods, single-crystal X-ray diffraction (6f). The in vitro anti-tuberculosis activity for newly-synthesized derivatives has been screened against Mycobacterium tuberculosis. Among all, six compounds 6e, 6k, 6l, 6n, 6q and 6r exhibited equal potent activity compared to standard drug ethambutol (MIC: 1.56 mu g/mL) and another compound 6h exhibited outstanding activity (MIC: 0.78 mu g/mL) than the standard drug ethambutol. Cytotoxic nature of the anti-TB active compounds was evaluated against RAW 264.7 cells. The 6h, 6e, 6k, 6l, 6n, 6q and 6r exhibited lower toxicity which could be promising hits for anti-tuberculosis.

COA of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Pogaku, V; Krishna, VS; Sriram, D; Rangan, K; Basavoju, S or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. In 2020.0 TETRAHEDRON LETT published article about COUNTERION in [Lai, Jia-Wei; Liu, Zhao-Yang; Chen, Xiao-Yan; Zhang, Hao; Liu, Hai-Yang] South China Univ Technol, Dept Chem, Key Lab Funct Mol Engn Guangdong Prov, Guangzhou 510640, Peoples R China in 2020.0, Cited 36.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Cobalt(III) corrole was firstly applied to the hydration of terminal alkynes. The alkyne hydration proceeded in good to excellent yield with 0.03 to 0.3 mol% cobalt corrole catalyst loading. A wide range of substrates were tolerated. Particularly, the reaction can give 90% yield in a gram scale experiment. (C) 2020 Elsevier Ltd. All rights reserved.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Lai, JW; Liu, ZY; Chen, XY; Zhang, H; Liu, HY or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMF via copper-catalyzed C(sp(3))-H amidination published in 2019.0, Reprint Addresses Liu, Q; Guo, CC (corresponding author), Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp(3))-H amidination. Various methyl ketones react readily with aromatic amines and DMF, producing 2-oxo-acetamidines in yields of 47 to 92%. This protocol features the simultaneous formation of C-N and C?N bonds using DMF and aromatic amines as two different nitrogen sources. It thus provides an efficient approach to construct acyclic amidines via three C(sp(3))-H bond amidination. Based on the preliminary experiments, a plausible mechanism of this transformation is disclosed.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Xie, DK; He, W; Xiao, J; Wu, Y; Guo, YJ; Liu, Q; Guo, CC or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis and characterization of heterocyclic core-based polybenzoxazine matrices WOS:000454228400026 published article about BENZOXAZINE MONOMERS; THERMOSETTING RESIN; PERFORMANCE; NANOCOMPOSITES; POLYIMIDE; ETHER; PROTONATION; IMPROVEMENT; FLUORENE; DESIGN in [Selvi, M.] Anna Univ, Dept Chem Engn, Polymer Composite Lab, Madras 600025, Tamil Nadu, India; [Devaraju, S.] VFSTR, Dept Sci & Humanities, Div Chem, Guntur 522213, Andhra Pradesh, India; [Vengatesan, M. R.] Petr Inst, Dept Chem Engn, Abu Dhabi, U Arab Emirates; [Alagar, M.] VFSTR, Ctr Excellence Adv Mat Mfg Proc & Characterisat C, Guntur 522213, Andhra Pradesh, India in 2019.0, Cited 39.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In the present work, four types of heterocyclic core-based polybenzoxazine matrices (HC-PBZ) developed based on pyridine, thiophene, and thiazole and their molecular structure, thermal, flame-retardant and luminescent properties were studied and discussed. The heterocyclic core-based benzoxazine monomers (HC-BZ) were synthesized using two types of phenols (phenol, and 4-hydroxyphenylacetonitrile), and two types of heterocyclic diamines [2,6-Bis-(4-aminophenyl)-4-thiophen-2-yl-pyridine (BATP) and 4-(2-methylthiazol-5-yl)-2,6-bis-(4-aminophenyl)-pyridine (BAMTP)] with formaldehyde through Mannich reaction. The structure of the four HC-BZ monomers was confirmed by various spectral analysis such as Fourier-transform infrared spectroscopy (FTIR), and Nuclear magnetic resonance spectroscopy ((HNMR)-H-1 and (CNMR)-C-13). All the four HC-BZ monomers have the maximum range of curing temperature (T-p) between 252 and 267 degrees C. Data resulted from the thermal studies indicate that the HC-PBZ exhibits better T-g,T- thermal stability and flame-retardant properties. Among the four HC-PBZ systems the thiazole based system possesses the higher value of T-g of 268 degrees C and thermal stability when compared to those of other matrices. It was also observed that the HC-BZ monomers and HC-PBZ polymers exhibit a photoluminescent (PL) emission range between 441-445 and 414-417nm, respectively. Overall, it seems that the thiazole and thiophene based HC-PBZ can be considered as competitive materials for luminescent applications with high thermal and flame-retardant properties. (c) 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47134.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Selvi, M; Devaraju, S; Vengatesan, MR; Alagar, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem