Category: 100-19-6

Recently I am researching about DEFECTIVE GRAPHENE; ELECTROCATALYTIC ACTIVITY; REDUCTION; CATALYSTS; FRAMEWORKS; EVOLUTION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21306132]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Li, GZ; Zheng, SY; Wang, L; Zhang, XW. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. SDS of cas: 100-19-6

Chemoselective hydrogenation of nitroarenes to anilines is of great importance for the manufacture of pharmaceuticals, fine chemicals, and dyes. In this study, a series of metal-free N-doped carbon nanotubes (NCNTs) have been prepared by the carbonization of in situ polymerized pyrrole on CNTs. The concentration of pyrrole, pyrolysis temperature, and the outside diameter of CNTs were investigated to improve the catalytic performance. As characterized by Raman and X-ray photoelectron spectroscopy (XPS), the optimal catalyst (NCNTs-800) possessed a unique structure doped with the same content of pyrrolic N and graphitic N. The activity and selectivity of NCNTs-800 have been evaluated for the selective hydrogenation of substituted nitroarenes. Highly selective hydrogenation of the nitro group of 12 different substrates has been achieved on NCNTs-800, even in the presence of a fragile iodo group. The hydrogenation reaction on N-doped CNTs from polypyrrole involved a mixture of different hydrogen species including nonpolar H radicals. In addition, stability and recyclability of NCNTs-800 have been tested.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, GZ; Zheng, SY; Wang, L; Zhang, XW or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. In 2019.0 J ORG CHEM published article about 3+3 ANNULATION REACTION; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; MICHAEL ADDITION; CYCLIZATION REACTIONS; EFFICIENT SYNTHESIS; SPIROPYRAZOLONES; CASCADE; CYCLOADDITION; EPOXIDATION in [Shen, Shou-Jie; Du, Xiao-Li; Zhao, Ming-Gang] Shanxi Normal Univ, Key Lab Magnet Mol, Magnet Informat Mat Minist Educ, Sch Chem & Mat Sci, Linfen 041004, Peoples R China; [Xu, Xiao-Li; Liang, Jin-Yan] Shanxi Normal Univ, Coll Life Sci, Linfen 041004, Peoples R China in 2019.0, Cited 70.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The regioselective N-addition/substitution reaction between alpha-alkylidene pyrazolinones and propargyl sulfonium salts has been developed to construct functionalized allylthio-containing pyrazolones with moderate to excellent yields. alpha-Alkylidene pyrazolinones act as N-nucleophilic agents which are distinguished from reported C-nucleophilic reactions. Excellent regioselectivity, readily available starting materials, the broad range of substrates, gram-scale synthesis, and simple operation illustrate the synthetic advantages of this new reaction pathway.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shen, SJ; Du, XL; Xu, XL; Zhao, MG; Liang, JY or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. In 2019.0 MOL DIVERS published article about BENZAMIDE; DISCOVERY; ALPHA; ACIDS in [Nian, Si-Yun; Jiang, Zheng-Li] Taizhou Hosp Zhejiang Prov, Dept Clin Pharm, Xi Men St 150, Linhai 317000, Zhejiang, Peoples R China; [Nian, Si-Yun; Wang, Guo-Ping; Xiao, Ying] China State Inst Pharmaceut Ind, Shanghai Inst Pharmaceut Ind, Shanghai 201203, Peoples R China; [Nian, Si-Yun; Wang, Guo-Ping] Aurisco Pharmaceut Yangzhou Co Ltd, Yangzhou 225100, Jiangsu, Peoples R China; [Huang, Mo-Han; Zhou, Yi-Huan; Tan, Xiang-Duan] Guilin Med Univ, Coll Pharm, Guilin 541004, Peoples R China in 2019.0, Cited 21.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Most of reported steroidal FXR antagonists are restricted due to low potency. We described the design and synthesis of novel nonsteroidal scaffold SIPI-7623 derivatives as FXR antagonists. The most potent compound A-11 (IC50 = 7.8 +/- 1.1 mu M) showed better activity compared to SIPI-7623 (IC50 = 40.8 +/- 1.7 mu M) and guggulsterone (IC50 = 45.9 +/- 1.1 mu M). Docking of A-11 in FXR’s ligand-binding domain was also studied.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Nian, SY; Wang, GP; Jiang, ZL; Xiao, Y; Huang, MH; Zhou, YH; Tan, XD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about ALKYL-ARYL KETONES; IR-F-BINAPHANE; ENANTIOSELECTIVE HYDROGENATION; IDENTIFICATION; SALTS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772155, 21402155, 21602172]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Wu, ZT; Du, SZ; Gao, GR; Yang, WK; Yang, XY; Huang, HZ; Chang, MX. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Product Details of 100-19-6

The secondary amine participating asymmetric reductive amination remains an unsolved problem in organic synthesis. Here we show for the first time that secondary amines are capable of effectively serving as N-sources in direct asymmetric reductive amination to afford corresponding tertiary chiral amines with the help of a selected additive set under mild conditions (0-25 degrees C). The applied chiral phosphoramidite ligands are readily prepared from BINOL and easily modified. Compared with common tertiary chiral amine synthetic methods, this procedure is much more concise and scalable, as exemplified by the facile synthesis of rivastigmine and N-methyl-1-phenylethanamine.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wu, ZT; Du, SZ; Gao, GR; Yang, WK; Yang, XY; Huang, HZ; Chang, MX or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 ASIAN J ORG CHEM published article about DEFECTS; QUINAZOLINONES; OPTIMIZATION; MOF in [Linh Ho Thuy Nguyen; Trang Thi Thu Nguyen; Thi Dang, Y.; Tan Le Hoang Doan] Vietnam Natl Univ Ho Chi Minh City VNU HCM, Ctr Innovat Mat & Architectures INOMAR, Ho Chi Minh City 721337, Vietnam; [Linh Ho Thuy Nguyen; Trang Thi Thu Nguyen; Phuong Hoang Tran; Tan Le Hoang Doan] Vietnam Natl Univ Ho Chi Minh City, Dept Organ Chem, Fac Chem, Univ Sci, Ho Chi Minh City 721337, Vietnam in 2019.0, Cited 50.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

Zr-based metal-organic frameworks have been considered promising heterogeneous catalysts in various reactions. It has been proven that the defect sites in these frameworks, which result from deficiency of linkers, could act as the reaction active sites. In this work, microwave irradiation was used for rapid synthesis and increasing defects on Zr-6 clusters of metal-organic framework UiO-66. Powder X-ray diffraction, thermal gravimetric analysis, and N-2 sorption isotherms were performed to characterize and calculate the defect number in the framework. UiO-66 prepared by microwave method for a few minutes could reach 1.8 missing linkers per cluster. The material with acetic acid as a co-catalyst showed highly heterogeneous catalytic activity in the solvent-free heterocyclization of 2,2-disubstituted 2,3-dihydroquinazolin-4(1H)-ones from anthranilamide and ketones/aldehydes. The synthetic scheme consisted of zirconium cluster catalysed carbonyl group of anthranilamide to achieve the C-N propitious combination and succeeding ring closure process.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Nguyen, LHT; Nguyen, TTT; Dang, YT; Tran, PH; Doan, TLH or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 EUR J MED CHEM published article about BREAST-CANCER; CRYSTAL-STRUCTURE; CDK INHIBITORS; AGENTS DESIGN; APOPTOSIS; CELLS; IX; ENHANCEMENT; DERIVATIVES; SELECTIVITY in [Said, Mohamed A.; Soliman, Dalia H.] Egyptian Russian Univ, Coll Pharm, Dept Pharmaceut Chem, POB 11829, Cairo, Egypt; [Eldehna, Wagdy M.] Kafrelsheikh Univ, Fac Pharm, Dept Pharmaceut Chem, POB 33516, Kafrelsheikh, Egypt; [Nocentini, Alessio; Bonardi, Alessandro; Supuran, Claudiu T.] Univ Florence, Dept NEUROFARBA, Sect Pharmaceut & Nutraceut Sci, Polo Sci, Via U Schiff 6, I-50019 Florence, Italy; [Nocentini, Alessio; Bonardi, Alessandro; Gratteri, Paola] Univ Firenze, Dept NEUROFARBA, Pharmaceut & Nutraceut Sect, Via U Schiff 6, I-50019 Florence, Italy; [Nocentini, Alessio; Bonardi, Alessandro; Gratteri, Paola] Univ Firenze, Lab Mol Modeling Cheminformat & QSAR, Via U Schiff 6, I-50019 Florence, Italy; [Fahim, Samar H.; Abou-Seri, Sahar M.] Cairo Univ, Fac Pharm, Dept Pharmaceut Chem, Kasr El Aini St,POB 11562, Cairo, Egypt; [Elgazar, Abdullah A.] Kafrelsheikh Univ, Fac Pharm, Dept Pharmacognosy, POB 33516, Kafrelsheikh, Egypt; [Krystof, Vladimir] Palacky Univ, Lab Growth Regulators, Slechtitelu 27, Olomouc 78371, Czech Republic; [Krystof, Vladimir] Czech Acad Sci, Inst Expt Bot, Slechtitelu 27, Olomouc 78371, Czech Republic; [Soliman, Dalia H.] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Chem, POB 11471, Cairo, Egypt; [Abdel-Aziz, Hatem A.] Natl Res Ctr, Dept Appl Organ Chem, Cairo 12622, Egypt; [Krystof, Vladimir] Palacky Univ, Fac Med & Dent, Inst Mol & Translat Med, Hnevotinska 5, Olomouc 77900, Czech Republic in 2020.0, Cited 56.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

In the present study, we report the design and synthesis of novel CAN508 sulfonamide-based analogues (4, 8a-e, 9a-h and 10a-e) as novel carbonic anhydrase (CA) inhibitors with potential CDK inhibitory activity. A bioisosteric replacement approach was adopted to replace the phenolic OH of CAN508 with a sulfamoyl group to afford compound 4. Thereafter, a ring-fusion approach was utilized to furnish the 5/5 fused imidazopyrazoles 8a-e which were subsequently expanded to 6/5 pyrazolopyrimidines 9a-h and 10a-e. All the synthesized analogues were evaluated for their inhibitory activity toward isoforms hCA I, II, IX and XII. The target tumor-associated isoforms hCA IX and XII were effectively inhibited with KIs ranges 6-67.6 and 10.1-88.6 nM, respectively. Furthermore, all compounds were evaluated for their potential CDK2 and 9 inhibitory activities. Pyrazolopyrimidines 9d, 9e and 10b displayed weak CDK2 inhibitory activity (IC50 = 6.4, 8.0 and 11.6 mu M, respectively), along with abolished CDK9 inhibitory activity. This trend suggested that pyrazolopyrimidine derivatives merit further optimization to furnish more effective CDK2 inhibitor lead. On account of their excellent activity and selectivity towards hCA IX and XII, pyrazolopyrimidines 10 were evaluated for their anti-proliferative activity toward breast cancer MCF-7 and MDA-MB-468 cell lines under normoxic and hypoxic conditions. The most potent anti-proliferative agents 10a, 10c and 10d significantly increased cell percentage at sub-G1 and G2-M phases with concomitant decrease in the S phase population in MCF-7 treated cells. Finally, a docking study was undertaken to investigate the binding mode for the most selective hCA IX and XII inhibitors 10a-e, within hCA II, IX and XII active sites. (C) 2020 Elsevier Masson SAS. All rights reserved.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Said, MA; Eldehna, WM; Nocentini, A; Fahim, SH; Bonardi, A; Elgazar, AA; Krystof, V; Soliman, DH; Abdel-Aziz, HA; Gratteri, P; Abou-Seri, SM; Supuran, CT or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about C BOND-CLEAVAGE; AEROBIC OXIDATION; ELECTRON-TRANSFER; ENAMINO ESTERS; FACILE ACCESS; H ACTIVATION; TRANSITION; TEMPO; CYCLIZATION; EFFICIENT, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21873041, 21632001, 21422205]; 111 projectMinistry of Education, China – 111 Project; Program for Changjiang Scholars and Innovative Research Team in UniversityProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT-15R28]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [lzujbky-2016-ct02, lzujbky-2016-ct08]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Zhan, JL; Wu, MW; Wei, D; Wei, BY; Jiang, Y; Yu, W; Han, B. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Name: 1-(4-Nitrophenyl)ethanone

A 4-HO-TEMPO-catalyzed redox strategy for the synthesis of pyridines through the annulation of cyclopropanols and oxime acetates has been developed. This protocol features good functional group tolerance and high chemoselectivity and also promises to be efficient for the late-stage functionalization of skeletons of drugs and natural products. Mechanism studies indicate that the reaction involves the in situ generated alpha,beta-unsaturated ketones and imines as the key intermediates, which are derived from cyclopropanols and oxime acetates via a TEMPO/TEMPOH redox cycle, respectively. The pyridine products are formed as a result of annulation of enones with imines followed by TEMPO-catalyzed oxidative aromatization by excess oxime acetates. This method not only realizes the TEMPO-catalyzed redox reaction but also broadens the frontiers for TEMPO in catalysis.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhan, JL; Wu, MW; Wei, D; Wei, BY; Jiang, Y; Yu, W; Han, B or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Synergistic Catalysis of Se and Cu for the Activation of alpha-Hof Methyl Ketones with Molecular Oxygen/Alcohol to Produce alpha-KetoAcetals(dagger) published in 2020.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Yu, L (corresponding author), Yangzhou Univ, Sch Chem & Chem Engn, Yangzhou 225002, Jiangsu, Peoples R China.; Jiang, XF (corresponding author), East China Normal Univ, Dept Chem, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Summary of main observation and conclusion Selenium and copper synergistically catalyzed the oxidation/alkoxylation of methyl ketones to synthesize alpha-keto acetals directly. Using O(2)as oxidant and alcohol as solvent and alkoxylation reagent, the reaction is practical from industrial viewpoint. Mechanistic studies revealed that copper promoted the oxidation of organoselenium intermediates with O(2)to allow the key rearrangement and selenoxidesyn-elimination regenerating the catalytically active organoselenium species.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chen, C; Cao, ZC; Zhang, X; Li, YM; Yu, L; Jiang, XF or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article OH/Na co-functionalized carbon nitride: directional charge transfer and enhanced photocatalytic oxidation ability WOS:000509894100024 published article about FACILE SYNTHESIS; REACTANTS ACTIVATION; NO ADSORPTION; DOPED G-C3N4; EFFICIENT; NANOSHEETS; ZIRCONIA; REACTIVITY; VACANCIES; MECHANISM in [Wang, Jiadong; Chen, Ruimin; Yuan, Chaowei; Dong, Fan; Sun, Yanjuan] Chongqing Technol & Business Univ, Coll Environm & Resources, Chongqing Key Lab Catalysis & New Environm Mat, Chongqing 400067, Peoples R China; [Wang, Jiadong; Cui, Wen; He, Ye; Yuan, Chaowei; Sheng, Jianping; Li, Jieyuan; Dong, Fan; Sun, Yanjuan] Univ Elect Sci & Technol China, Inst Fundamental & Frontier Sci, Res Ctr Environm Sci & Technol, Chengdu 611731, Peoples R China; [Cui, Wen] Southwest Petr Univ, Sch Mat Sci & Engn, Ctr New Energy Mat & Thchnol, Chengdu 610500, Peoples R China; [Zhan, Yuxin] Chongqing Univ, Coll Mat Sci & Engn, Chongqing 400044, Peoples R China in 2020, Cited 60. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

Graphitic carbon nitride (g-C3N4, CN for short) is a compelling visible-light responsive photocatalyst. However, its photocatalytic efficiency is low due to the random carrier transfer in planes and insufficient redox potential. Herein, we build oxygen functional group modified sodium-doped carbon nitride (OH/Na co-functionalized carbon nitride) to promote directional transfer of charge carriers for acceleration of separation and enhance redox potential for efficient oxidation of NO in air. Specifically, the function of sodium atoms could control the directional transfer of random carriers from the intralayer to the oxygen functional group-modified surface for the purpose of effectively reducing photogenerated electron-hole recombination. Meanwhile, the modification by oxygen-containing functional groups could adjust the band structure of CN, thereby increasing the oxidation-reduction potential of NO in the photocatalyst. The transformation pathways and reaction mechanism of photocatalytic NO oxidation on CN and OH/Na co-functionalized carbon nitride have also been explicated by ESR spectroscopy and in situ DRIFTS and compared. This work provides a new method for simultaneously controlling the random transfer of carriers and adjusting the energy band structure of CN to optimize its photocatalytic efficiency. It is also possible to extend this strategy to improve the performance of other 2D layered catalysts for photocatalytic oxidation.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wang, JD; Cui, W; Chen, RM; He, Y; Yuan, CW; Sheng, JP; Li, JY; Zhan, YX; Dong, F; Sun, YJ or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. Recently I am researching about CARBONYL-COMPOUNDS; METAL-FREE; CORRESPONDING 1,3-OXATHIOLANES; SYNTHETIC APPLICATIONS; ASYMMETRIC-SYNTHESIS; RADICAL-ADDITION; SILICA-GEL; EFFICIENT; CATALYST; CONVERSION, Saw an article supported by the Ministry of Science and Technology, TaiwanMinistry of Science and Technology, Taiwan [Most 107-2113-M-005-019-MY3]; National Chung Hsing University, Research Center for Sustainable Energy and Nanotechnology (RCSEN); Innovation and Development Center of Sustainable Agriculture (IDCSA) from The Featured Areas Research Center Program within Ministry of Education (MOE) in Taiwan. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Liu, YC; Reddy, DM; Chen, XA; Shieh, YC; Lee, CF. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

In synthetic chemistry, the protection of aldehydes and ketones is crucial during multistep synthesis of complex molecules. Organic chemists have paid substantial attention to the synthesis of 1,3-oxathiolanes and 1,3-oxathianes because of their considerable stability under acidic conditions and ease of removal of protecting groups. In this paper, we report the mild and efficient oxathiacetalization of aldehydes with 2-mercaptoethanol and 3-mercaptopropan-1-ol through visible-light-promoted eosin-Y catalyzed C-S and C-O bond formation at ambient temperature under metal-free conditions. This catalytic system also affords oxathiacetalization of ketones through photoredox catalysis.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Liu, YC; Reddy, DM; Chen, XA; Shieh, YC; Lee, CF or concate me.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem