Category: 100-19-6

An article Design of Manganese Phenol Pi-complexes as Shvo-type Catalysts for Transfer Hydrogenation of Ketones WOS:000463960000006 published article about ASYMMETRIC HYDROGENATION; IRON; EFFICIENT; MECHANISM; CHEMISTRY; ALDEHYDES; NITRILES; ALCOHOLS; LIGANDS; METALS in [Shvydkiy, Nikita, V; Nelyubina, Yulia, V; Perekalin, Dmitry S.] Russian Acad Sci, Nesmeyanov Inst Organoelement Cpds, 28 Vavilova, Moscow 119991, Russia; [Vyhiyskyi, Oleksandr] Lomonosov Moscow State Univ, Dept Chem, 1-3 Leninskie Gory, Moscow 119991, Russia; [Perekalin, Dmitry S.] Plekhanov Russian Univ Econ, 36 Stremyannyi Pereulok, Moscow 117997, Russia in 2019.0, Cited 55.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Catalytic hydrogenation is one of the most important reactions both in academic research and industry. We explored ability of the manganese pi-complexes to act as Shvo-type catalysts for transfer hydrogenation of ketones. DFT calculations suggested that the transfer of hydrogen atoms from the hypothetical intermediate [(C6Me3H2OH)Mn(CO)(2)H] to acetone has low activation barrier of 10.9 kcal mol(-1). Experimentally a number of ketones with various functional groups (OMe, NH2, Cl, CF3, pyridyl) were successfully reduced in isopropanol at 90 degrees C in the presence of the complex[(C6Me3H2OH)Mn(CO)(3)]BF4 (1 mol %) and (BuOK)-Bu-t (75 mol %). However, further investigation revealed that the reduction was mainly promoted by base rather than the manganese complex.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shvydkiy, NV; Vyhiyskyi, O; Nelyubina, YV; Perekalin, DS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. In 2021.0 NEW J CHEM published article about POLY(ETHYLENE GLYCOL); CYCLOADDITION; DERIVATIVES; LIBRARY; 3-AMINO-2-OXINDOLES; SPIROINDOLONES; CONSTRUCTION; ANTAGONIST; SCAFFOLDS; RECEPTOR in [Yue, Guizhou; Jiang, Dan; Dou, Zhengjie; Li, Sicheng; Feng, Juhua; Zhang, Li; Wang, Xianxiang] Sichuan Agr Univ, Coll Sci, Yaan 625014, Sichuan, Peoples R China; [Chen, Huabao; Yang, Chunping] Sichuan Agr Univ, Coll Agron, Chengdu 611130, Sichuan, Peoples R China; [Yin, Zhongqiong; Song, Xu; Liang, Xiaoxia] Sichuan Agr Univ, Coll Vet Med, Chengdu 611130, Sichuan, Peoples R China; [Lu, Cuifen] Hubei Univ, Hubei Collaborat Innovat Ctr Adv Organochem Mat, Wuhan 430062, Peoples R China; [Lu, Cuifen] Hubei Univ, Key Lab Synth & Applicat Organ Funct Mol, Minist Educ, Wuhan 430062, Peoples R China in 2021.0, Cited 62.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The umpolung Michael addition of isatin N,N’-cyclic azomethine imine 1,3-dipoles with chalcones is reported. The reaction could be finished within a very short time (0.3-2 min), with 3,3-disubstituted oxindole derivatives obtained in moderate to excellent yields with promising dr values. Unusual Michael adducts were obtained in moderate to high yields (26-98%) with low to high diastereoselectivities (0.8 : 1 to 8.5 : 1 dr). All the synthesized compounds (3, 3′, 4, 5, 5′, 7, 7′, 9 and 9′) were well characterized by FTIR, NMR, and mass spectral analyses and further confirmed by the single-crystal X-ray diffraction analysis of compounds 3aa and 4n.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Yue, GZ; Jiang, D; Dou, ZJ; Li, SC; Feng, JH; Zhang, L; Chen, HB; Yang, CP; Yin, ZQ; Song, X; Liang, XX; Wang, XX; Lu, CF or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Recyclable Itaconic Acid with Water as Green Catalytic System: Synthesis of Substituted 1,5-Benzodiazepine Derivatives at Room Temperature WOS:000510247300016 published article about VERSATILE BUILDING-BLOCK; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; ENVIRONMENTALLY BENIGN; O-PHENYLENEDIAMINE; ORGANIC-REACTIONS; FACILE SYNTHESIS; NANOCATALYST in [Tamuli, Kashyap J.; Bordoloi, Manobjyoti] North East Inst Sci & Technol, CSIR, Chem Sci & Technol Div, Jorhat 785006, Assam, India; [Tamuli, Kashyap J.; Bordoloi, Manobjyoti] Acad Sci & Innovat Res, Jorhat 785006, Assam, India in 2020.0, Cited 89.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

The construction of new C-N chemical bonds through co-condensation reaction in water media as sole solvent, especially without the use of any metal catalyst has undergoes green protocols. Herein, we describe a water-mediated and metal-free mild protocol for easily accessing of structurally and electronically diverse 1,5-benzodiazepine analogous by using biodegradable naturally occurring itaconic acid (20 mol%) in 30 minutes with excellent yields. The simplicity in reaction operation, reusability of the catalytic system and simple filtration to get the desired product make this reaction as green synthetic pathway upto multi gram scale level.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Tamuli, KJ; Bordoloi, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. In 2020.0 BIOORG CHEM published article about BIOLOGICAL EVALUATION; PHENYL AMIDES; DERIVATIVES; PYRIDINES; DESIGN in [Attia, Mohamed H.] October 6 Univ, Dept Pharmaceut Chem, Fac Pharm, Giza, Egypt; [Elrazaz, Eman Z.; Abouzid, Khaled A. M.] Ain Shams Univ, Fac Pharm, Pharmaceut Chem Dept, Cairo 11566, Egypt; [El-Emam, Soad Z.] October 6 Univ, Fac Pharm, Dept Pharmacol & Toxicol, Giza, Egypt; [Taher, Azza T.] Cairo Univ, Fac Pharm, Pharmaceut Organ Chem Dept, Cairo, Egypt; [Abdel-Aziz, Hatem A.] Natl Res Ctr, Dept Appl Organ Chem, Cairo 12622, Egypt; [Abouzid, Khaled A. M.] Univ Sadat City, Fac Pharm, Dept Organ & Med Chem, Sadat City, Egypt in 2020.0, Cited 27.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A series of 2-phenyl-7-(aryl)pyrazolo [1,5-a]pyrimidine-3-carbonitriles 11a-j and 2-phenyl-7-(aryl)pyrazolo[1,5-a]pyrimidine-3,6-dicarbonitriles 16a-c was synthesized by the reaction of 5-amino-3-phenyl-1H-pyrazole-4-carbonitrile (5) with 3-(dimethylamino)-1-arylprop 2 en 1 ones 6a-j or 2-aryl-3-(dimethylamino)acrylonitriles 12a-c, respectively. In addition, 7-amino-5-oxo-2-phenyl-4,5-dihydropyrazolo [1,5-a]pyrimidine-3-carbonitrile (22) was prepared from the reaction of compound 5 with ethyl cyanoacetate. The anticancer activity of the newly synthesized compounds against Huh-7, HeLa, MCF-7 and MDA-MB231 cell lines showed moderate activity of compound 11 f as anti-proliferative agent against Huh-7 cell line with IC50 = 6.3 mu M when compared with doxorubicin (IC50, = 3.2 mu M). On the other hand, compound 16b revealed potent anti-proliferative activity against HeLa cell line with IC50, = 7.8 mu M when compared with doxorubicin (IC50, = 8.1 mu M). Also compound 11i exhibited a promising anti-proliferative activity against MCF-7 cell line (IC50, = 3.0 mu M) whereas IC50 of doxorubicin = 5.9 mu M, finally compounds 11i and 16b have potent activity as anti-proliferative agents against MDA-MB231 cell line with IC50, = 4.32 and 5.74 mu M, respectively when compared with doxorubicin (IC50 = 6.0 mu M).

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Attia, MH; Elrazaz, EZ; El-Emam, SZ; Taher, AT; Abdel-Aziz, HA; Abouzid, KAM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 J AM CHEM SOC published article about ASYMMETRIC TRANSFER HYDROGENATION; PHOTOREDOX CATALYSIS; CYCLIZATION; REDUCTION; COMPLEXES; COFACTOR; BINDING; KETONES; DESIGN; AMINES in [Wei, Jianwei; Zhao, Liang; He, Cheng; Zheng, Sijia; Duan, Chunying] Dalian Univ Technol, Zhang Dayu Coll Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China; [Reek, Joost N. H.] Univ Amsterdam, Vant Hoff Inst Mol Sci, Sci Pk 904, NL-1098 XH Amsterdam, Netherlands in 2019.0, Cited 60.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Safety of 1-(4-Nitrophenyl)ethanone

Switchable selective hydrogenation among the groups in multifunctional compounds is challenging because selective hydrogenation is of great interest in the synthesis of fine chemicals and pharmaceuticals as a result of the importance of key intermediates. Herein, we report a new approach to highly selectively (>99%) reducing C=X (X = O, N) over the thermodynamically more favorable nitro groups locating the substrate in a metal-organic capsule containing NADH active sites. Within the capsule, the NADH active sites reduce the double bonds via a typical 2e(-) hydride transfer hydrogenation, and the formed excited-state NAD(+) mimics oxidize the reductant via two consecutive 1e(-) processes to regenerate the NADH active sites under illumination. Outside the capsule, nitro groups are highly selectively reduced through a typical 1e(-) hydrogenation. By combining photoinduced 1e(-) transfer regeneration outside the cage, both 1e(-) and 2e(-) hydrogenation can be switched controllably by varying the concentrations of the substrates and the redox potential of electron donors. This promising alternative approach, which could proceed under mild reaction conditions and use easy-to-handle hydrogen donors with enhanced high selectivity toward different groups, is based on the localization and differentiation of the 2e(-) and 1e(-) hydrogenation pathways inside and outside the capsules, provides a deep comprehension of photocatalytic microscopic reaction processes, and will allow the design and optimization of catalysts. We demonstrate the advantage of this method over typical hydrogenation that involves specific activation via well-modified catalytic sites and present results on the high, well-controlled, and switchable selectivity for the hydrogenation of a variety of substituted and bifunctional aldehydes, ketones, and imines.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wei, JW; Zhao, L; He, C; Zheng, SJ; Reek, JNH; Duan, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. Li, RR; Jin, YX; Wang, XQ; Zhan, SY; Zhu, YW; Zheng, MM; Zhao, J; Han, DM in [Li, Rongrong; Jin, Yanxian; Wang, Xiaoqiang; Zhan, Shiyun; Zhu, Yuwei; Zheng, Mengmeng; Han, Deman] TaiZhou Univ, Sch Pharmaceut & Mat Engn, Taizhou 318000, Zhejiang, Peoples R China; [Zhao, Jia] Zhejiang Univ Technol, Ind Catalysis Inst, Hangzhou 310014, Zhejiang, Peoples R China published Research and comparison of solid-liquid phase equilibrium and ternary phase diagrams of 1-(3-nitrophenyl)ethanone+1-(4-nitrophenyl)ethanone in different solvents in 2019.0, Cited 20.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The ternary phase equilibrium for 1-(3-nitrophenyl)ethanone and 1-(4-nitrophenyl)ethanone in methanol or n-propanol were determined at 298.15, 308.15 K and 318.15 K under atmospheric pressure in this work. Based on the measured mutual solubility data, the isothermal ternary phase diagrams were constructed. In each ternary phase diagram, there were one co-saturated point, two boundary curves, and three crystalline regions. The crystallization region of 1-(3-nitrophenyl)ethanone was about the same as 1-(4-nitrophenyl)ethanone at all researched temperatures. The NRTL model was used to correlate the solubility of the ternary 1-(3-nitrophenyl)ethanone + 1-(4-nitrophenyl)ethanone + solvents. The correlation results were evaluated by the values of relative average deviation (RAD) and root-mean-square deviation (RMSD), and their values were 4.18 x 10(-2) and 3.60 x 10(-3), respectively. The calculated results via this model were all acceptable for ternary solid-liquid phase equilibrium. The ternary phase diagram obtained will play an important part in separating the mixture of 1-(3-nitrophenyl)ethanone and 1-(4-nitrophenyl)ethanone. (C) 2019 Elsevier Ltd.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, RR; Jin, YX; Wang, XQ; Zhan, SY; Zhu, YW; Zheng, MM; Zhao, J; Han, DM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Increasing Scope of Clickable Fluorophores: Electrophilic Substitution of Ylidenemalononitriles WOS:000574920600022 published article about CHLORIDE; ENAMINES; CHEMISTRY; ACID; DERIVATIVES; REACTIVITY; PYRIDINES; NITRILES; ACCESS in [de Souza, Juliana M.; Abdiaj, Irini; McQuade, D. Tyler] Virginia Commonwealth Univ, Dept Chem & Life Sci Engn, Richmond, VA 23284 USA; [de Souza, Juliana M.; de Oliveira, Kleber T.] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil; [Chen, Jiaqi; Hanson, Kenneth] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA in 2020.0, Cited 36.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Recently, we demonstrated that ylidenemalononitriles (YMs) react with amines to form cyclic amidines and that the starting linear YMs are nonemissive in solution and the cyclic amidines are fluorescent. These turn-on systems were of interest to us because of their potential as biosensors and synthons for accessing functionalized pyridines. While our original method was promising, several limitations persisted, including access to more functionalized and polar-solvent-soluble structures as well as increased control over the rate of cyclization. Herein, we report a new approach that allows the electrophilic substitution of YMs. These substituted YMs exhibit faster turn-on rates, color tunability, access to polar-solvent-soluble species, and increased control over cyclization rate. This allowed us to significantly expand the fluorophore’s chemical space.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact de Souza, JM; Abdiaj, I; Chen, JQ; Hanson, K; de Oliveira, KT; McQuade, DT or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Visible light photoredox catalyzed deprotection of 1,3-oxathiolanes WOS:000505592200013 published article about CHEMOSELECTIVE DEPROTECTION; INTERCONVERSION; ALDEHYDES; EFFICIENT; SALT in [Yang, Mingyang; Xing, Zhimin; Xie, Xingang; She, Xuegong] Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China; [Fang, Bowen] Northwest Minzu Univ, Chem Engn Inst, Lanzhou 730030, Gansu, Peoples R China in 2020.0, Cited 29.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

An efficient visible light photoredox catalyzed aerobic deprotection of 1,3-oxathiolanes using organic dye Eosin Y as a photocatalyst is disclosed. The deprotection procedure features the use of a metal-free catalyst, mild conditions, a broad range of substrate scope, and good functional group tolerance. 35 examples were tested under the standard conditions and most of them afforded the deprotected products in modest to high yields.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Yang, MY; Xing, ZM; Fang, BW; Xie, XG; She, XG or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Li, GZ; Zheng, SY; Wang, L; Zhang, XW in AMER CHEMICAL SOC published article about DEFECTIVE GRAPHENE; ELECTROCATALYTIC ACTIVITY; REDUCTION; CATALYSTS; FRAMEWORKS; EVOLUTION in [Li, Guozhu; Zheng, Shuyi; Wang, Li; Zhang, Xiangwen] Tianjin Univ, Sch Chem Engn & Technol, Key Lab Green Chem Technol, Minist Educ, Tianjin 300072, Peoples R China; [Li, Guozhu; Wang, Li; Zhang, Xiangwen] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China in 2020.0, Cited 53.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Chemoselective hydrogenation of nitroarenes to anilines is of great importance for the manufacture of pharmaceuticals, fine chemicals, and dyes. In this study, a series of metal-free N-doped carbon nanotubes (NCNTs) have been prepared by the carbonization of in situ polymerized pyrrole on CNTs. The concentration of pyrrole, pyrolysis temperature, and the outside diameter of CNTs were investigated to improve the catalytic performance. As characterized by Raman and X-ray photoelectron spectroscopy (XPS), the optimal catalyst (NCNTs-800) possessed a unique structure doped with the same content of pyrrolic N and graphitic N. The activity and selectivity of NCNTs-800 have been evaluated for the selective hydrogenation of substituted nitroarenes. Highly selective hydrogenation of the nitro group of 12 different substrates has been achieved on NCNTs-800, even in the presence of a fragile iodo group. The hydrogenation reaction on N-doped CNTs from polypyrrole involved a mixture of different hydrogen species including nonpolar H radicals. In addition, stability and recyclability of NCNTs-800 have been tested.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, GZ; Zheng, SY; Wang, L; Zhang, XW or concate me.. Name: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Veliks, J; Kazia, A in [Veliks, Janis; Kazia, Armands] Latvian Inst Organ Synth, Aizkraukles 21, LV-1006 Riga, Latvia published Fluoromethylene Transfer from Diarylfluoromethylsulfonium Salts: Synthesis of Fluorinated Epoxides in 2019.0, Cited 55.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Diarylfluoromethyl sulfonium salts are efficient fluoromethylene transfer reagents equivalent to fluorocarbene, which is difficult to access. This was demonstrated by the development of a monofluorinated Johnson-Corey-Chaykovsky reaction with ketones and aldehydes, delivering uncommon 2-unsubstituted fluoroepoxides. This is the first evidence for the feasibility of sulfur fluoromethylylide and its action as a reaction intermediate.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Veliks, J; Kazia, A or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem