Category: 100-19-6

Sun, YW; Bei, YM; Wang, LZ in [Sun, Yue-Wei; Bei, Yue-Ming; Wang, Lan-Zhi] Hebei Normal Univ, Coll Chem & Mat Sci, Shijiazhuang 050024, Hebei, Peoples R China published A catalyst-free four-component domino reaction for the synthesis of functionalized 3-acyl-1,5-benzodiazepines in 2019.0, Cited 16.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Various functional 3-acyl-1,5-benzodiazepines containing carboxyl, ester and acyl groups at the 2-position were synthesized via an efficient, sustainable and catalyst-free domino reaction. During the synthesis process, one new cycle and four new bonds (one C-C, two C-N and one C=C) were constructed by the nucleophilic substitution, nucleophilic addition, dehydration and cyclization reaction by the H+ shift. Furthermore, a total of 26 examples were examined by reacting inexpensive starting materials of N,N-dimethylformamide dimethyl acetal, aromatic ketones, 1,2-phenylenediamine compounds and aldehyde derivatives. Therefore, it displayed a broad substrate scope, good functional group tolerance, high yields (77-97%) and the ease of obtaining target compounds without the involvement of toxic solvents and column chromatography, which provided a novel method for the synthesis of a wide variety of biologically relevant 1,5-benzodiazepines.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sun, YW; Bei, YM; Wang, LZ or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about PALLADIUM NANOPARTICLES; SELECTIVE HYDROGENATION; HETEROGENEOUS CATALYST; COUPLING REACTIONS; NITRO-COMPOUNDS; EFFICIENT; HALLOYSITE; OXIDE; NANOCOMPOSITE; NANOCATALYST, Saw an article supported by the Iran Polymer and Petrochemical Institute; Iran National Science FoundationIran National Science Foundation (INSF) [99011126]. HPLC of Formula: C8H7NO3. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Sadjadi, S; Koohestani, F. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

In attempt to take advantages of naturally occurring compounds for the catalysis, a novel composite composed of beta-cyclodextrin, dendrimer and bentonite clay is fabricated and utilized as a support for the stabilization of Pd nanoparticles. To prepare the support, bentonite is amino functionalized and then successively reacted with 2,4,6-trichloro-1,3,5-triazine and ethylenediamine to furnish a dendrimer of generation II on bentonite. Afterwards, the terminal functionalities of the dendrimer were adorned with cyclodextrin. Bentonite played role in the hetemgenation of the catalyst and improvement of the stability of the composite while, cyclodextrins served as molecular shuttles and capping agent for the as-prepared Pd nanoparticles. Dendrimer with multi nitrogen atoms, on the other hand, improved Pd anchoring through electrostatic interactions. The catalyst was applied for the hydrogenation of nitmarenes under mild reaction condition in aqueous media in a selective manner. Notably, the catalyst could be recovered and reused repeatedly.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sadjadi, S; Koohestani, F or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. Zaman, K; Rahim, F; Taha, M; Wadood, A; Shah, SAA; Gollapalli, M; Ullah, F; Ahmed, A in [Zaman, Khalid; Rahim, Fazal] Hazara Univ, Dept Chem, Mansehra 21300, Pakistan; [Taha, Muhammad] Imam Abdulrahman Bin Faisal Univ, IRMC, Dept Clin Pharm, POB 1982, Dammam 31441, Saudi Arabia; [Wadood, Abdul] Abdul Wali Khan Univ Mardan, Dept Biochem, Mardan 23200, Pakistan; [Shah, Syed Adnan Ali] Univ Teknol MARA UiTM, Atta Ur Rahman Inst Nat Prod Discovery, Puncak Alam Campus, Puncak Akan 42300, Selangor De, Malaysia; [Shah, Syed Adnan Ali] Univ Teknol MARA UiTM, Fac Pharm, Puncak Alam Campus, Puncak Alam 42300, Selangor Darul, Malaysia; [Gollapalli, Mohammed] Imam Abdulrahman Bin Faisal Univ, CCSIT, POB 1982, Dammam 3144, Saudi Arabia; [Ullah, Farhat] Univ Malakand, Dept Pharm, Khyber Pakhtunkhwa 18000, Kpk, Pakistan; [Ahmed, Ashfaq] Sarhad Univ Sci & Informat Technol, Dept Pharm, Peshawar, Pakistan published Synthesis, thymidine phosphorylase, angiogenic inhibition and molecular docking study of isoquinoline derivatives in 2019.0, Cited 35.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Isoquinoline analogues (KA-1 to 16) have been synthesized and evaluated for their E. coli thymidine phosphorylase inhibitory activity. Except compound 11, all other analogs showed outstanding thymidine inhibitory potential ranging in between 4.40 +/- 0.20 to 69.30 +/- 1.80 mu M when compared with standard drug 7-Deazaxanthine (IC50 = 38.68 +/- 4.42 mu M). Structure Activity Relationships has been established for all compounds, mainly based on substitution pattern on phenyl ring. All analogs were characterized by various spectroscopic techniques such as H-1 NMR, C-13 NMR and EI-MS. The binding interactions of isoquinoline analogues with the active site of TP enzyme, the molecular docking studies were performed. Furthermore, the angiogenic inhibitory potentials of isoquinoline analogues (KA-1-9, 14, 12 and 16) were determined in the presence of standard drug Dexamethasone based on percentage inhibitions at various concentrations. Herein this work analogue KA-12, 14 and 16 emerged with most potent angiogenic inhibitory potentials among the synthesized analogues.

Welcome to talk about 100-19-6, If you have any questions, you can contact Zaman, K; Rahim, F; Taha, M; Wadood, A; Shah, SAA; Gollapalli, M; Ullah, F; Ahmed, A or send Email.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article An Integrated Continuous Flow Micro-Total Ultrafast Process System (mu-TUFPS) for the Synthesis of Celecoxib and Other Cyclooxygenase Inhibitors WOS:000487577100012 published article about ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; PYRAZOLES; DIVERSE; DERIVATIVES; CATALYSIS in [Sthalam, Vinay Kumar; Singh, Ajay K.; Pabbaraja, Srihari] Indian Inst Chem Technol, CSIR, Dept Organ Synth & Proc Chem, Hyderabad 500007, Andhra Pradesh, India; [Sthalam, Vinay Kumar; Pabbaraja, Srihari] Acad Sci & Innovat Res AcSIR, CSIR HRDC Campus, Ghaziabad 201002, Uttar Pradesh, India in 2019.0, Cited 54.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

Integrated continuous manufacturing has emerged as a promising device for the rapid manufacturing of active pharmaceutical ingredients (APIs). We herein report a newly designed continuous flow micro-total process system platform for the rapid manufacturing of celecoxib, a selective nonsteroidal anti-inflammatory drug. This approach has been proven generally for the synthesis of several alkyl and aryl substituted pyrazoles. In order to minimize the tedious work-up process of potential reaction intermediates/products, we have developed a continuous flow extraction and separation platform to carry out the entire reaction sequence resulting in a short residence time with good yield. The present process was further extended to gram scale synthesis of the COX-2-related API, viz. celecoxib, in the continuous flow process.

Welcome to talk about 100-19-6, If you have any questions, you can contact Sthalam, VK; Singh, AK; Pabbaraja, S or send Email.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Recently I am researching about ENOYL-ACP REDUCTASE; BIOLOGICAL EVALUATION; TRIAZOLE DERIVATIVES; GALAHAD; AGENTS; DOCKING; DESIGN; BM212, Saw an article supported by the Indian Council of Medical Research, New DelhiIndian Council of Medical Research (ICMR) [BIC/12(13)2014]. Published in SPRINGER BIRKHAUSER in NEW YORK ,Authors: Joshi, SD; Kumar, SRP; Patil, S; Vijayakumar, M; Kulkarni, VH; Nadagouda, MN; Badiger, AM; Lherbet, C; Aminabhavi, TM. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Substituted phenylthiazolyl benzamide and pyrrolyl benzamide derivatives were developed using molecular hybridization technique to create novel lead antimycobacterial molecules used to fight against Mycobacteriumtuberculosis. The newly synthesized molecules have inhibited InhA, the enoyl-ACP reductase enzyme from the mycobacterial type II fatty acid biosynthetic pathway. Of these, compound 3b showed H-bonding interactions with Tyr158 and co-factor NAD(+) that binds the active site of InhA. All the molecules were screened for in vitro antitubercular activity against M. tuberculosis H(37)Rv, as well as some representative molecules as the inhibitors of InhA. Thirteen compounds exhibited good anti-TB activities (MIC = 1.6 mu g/mL), but only few representative molecules showed the moderate InhA enzyme inhibition activity. Basic core moiety and docked mode of all the synthesized compounds inside the proposed binding pocket of InhA with the final selected pharmacophore model molecular alignment for InhA receptor ligands. [GRAPHICS] .

Welcome to talk about 100-19-6, If you have any questions, you can contact Joshi, SD; Kumar, SRP; Patil, S; Vijayakumar, M; Kulkarni, VH; Nadagouda, MN; Badiger, AM; Lherbet, C; Aminabhavi, TM or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Cascade Synthesis of Pyrroles from Nitroarenes with Benign Reductants Using a Heterogeneous Cobalt Catalyst WOS:000564020400001 published article about SELECTIVE HYDROGENATION; REDUCTION; BENZIMIDAZOLES; NANOPARTICLES; DERIVATIVES; DISCOVERY; AFFINITY; IMINES; POTENT; AGENTS in [Ryabchuk, Pavel; Leischner, Thomas; Kreyenschulte, Carsten; Spannenberg, Anke; Junge, Kathrin; Beller, Matthias] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany in 2020, Cited 50. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

A bifunctional 3d-metal catalyst for the cascade synthesis of diverse pyrroles from nitroarenes is presented. The optimal catalytic system Co/NGr-C@SiO2-L is obtained by pyrolysis of a cobalt-impregnated composite followed by subsequent selective leaching. In the presence of this material, (transfer) hydrogenation of easily available nitroarenes and subsequent Paal-Knorr/Clauson-Kass condensation provides >40 pyrroles in good to high yields using dihydrogen, formic acid, or a CO/H2O mixture (WGSR conditions) as reductant. In addition to the favorable step economy, this straightforward domino process does not require any solvents or external co-catalysts. The general synthetic utility of this methodology was demonstrated on a variety of functionalized substrates including the preparation of biologically active and pharmaceutically relevant compounds, for example, (+)-Isamoltane.

Welcome to talk about 100-19-6, If you have any questions, you can contact Ryabchuk, P; Leischner, T; Kreyenschulte, C; Spannenberg, A; Junge, K; Beller, M or send Email.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Copper-Catalyzed Annulation of Oxime Acetates with alpha-Amino Acid Ester Derivatives: Synthesis of 3-Sulfonamido/Imino 4-Pyrrolin-2-ones WOS:000530076400016 published article about ONE-POT SYNTHESIS; KETOXIME CARBOXYLATES; VINYL AZIDES; CYCLIZATION; DIKETOPYRROLOPYRROLE; STRATEGY; VIOLACEIN; PYRIDINE; FUNCTIONALIZATION; HETEROANNULATION in [Miao, Chun-Bao; Zheng, An-Qi; Zhou, Li-Jin; Lyu, Xinyu; Yang, Hai-Tao] Changzhou Univ, Jiangsu Key Lab Adv Catalyt Mat & Technol, Sch Petrochem Engn, Changzhou 213164, Jiangsu, Peoples R China in 2020.0, Cited 66.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A copper-catalyzed annulation of oxime acetates and alpha-amino acid ester derivatives for the easy preparation of 4-pyrrolin-2-ones bearing a 3-amino group has been developed. This process features the oxidation of amines with oxime esters as the internal oxidant to produce the active 1,3-dinucleophilic and 1,2-dielectrophilic species concurrently. The subsequent nucleophilic cyclization realizes the efficient construction of 4-pyrrolin-2-one derivatives.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Miao, CB; Zheng, AQ; Zhou, LJ; Lyu, XY; Yang, HT or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about C-H-FUNCTIONALIZATION; METAL-FREE; PHOTOREDOX CATALYSIS; OXIDATIVE AMINATION; DIMETHYL-SULFOXIDE; STEREOSELECTIVE-SYNTHESIS; MICHAEL ADDITION; ROOM-TEMPERATURE; FACILE SYNTHESIS; BOND FORMATION, Saw an article supported by the Science and Engineering Research Board (SERB), IndiaDepartment of Science & Technology (India)Science Engineering Research Board (SERB), India [SB/FT/CS073/2014]. Category: benzodioxans. Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Rastogi, GK; Deb, ML; Baruah, PK. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Here we disclose a simple, visible-light-drivenZ-selective synthesis of methylthio-substituted 1,4-enedione in a single step promoted by Selectfluor. Dimethyl sulfoxide is used as both the ‘thio’ source and the solvent. Molecular iodine and potassium persulfate are used as catalyst and oxidant, respectively. White light (CFL-30W) is used as the light source. The proposed mechanism involves a Kornblum reaction followed by aldol reaction.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 CHEM COMMUN published article about HOMOGENEOUS CATALYSIS; CONJUGATE ADDITION; MOLECULAR-HYDROGEN; KETONES; SEMIHYDROGENATION; ACTIVATION; REDUCTION; ALDEHYDES; HYDRIDES in [Zimmermann, Birte M.; Kobosil, Sarah C. K.; Teichert, Johannes F.] Tech Univ Berlin, Inst Chem, Str 17 Juni 115, D-10623 Berlin, Germany in 2019.0, Cited 39.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

A simple and air-stable copper(I)/N-heterocyclic carbene complex enables the catalytic hydrogenation of enoates and enamides, hitherto unreactive substrates employing homogeneous copper catalysis and H2 as a terminal reducing agent. This atom economic transformation replaces commonly employed hydrosilanes and can also be carried out in an asymmetric fashion.

SDS of cas: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Zimmermann, BM; Kobosil, SCK; Teichert, JF or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Zinc Hydride-Catalyzed Hydrofuntionalization of Ketones published in 2020.0. Safety of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Nembenna, S (corresponding author), Homi Bhabha Natl Inst HBNI, Natl Inst Sci Educ & Res NISER, Sch Chem Sci, Bhubaneswar 752050, Odisha, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Three new dimeric bis-guanidinate zinc(II) alkyl, halide, and hydride complexes [LZnEt](2) (1), [LZnI](2) (2) and [LZnH](2) (3) were prepared. Compound 3 was successfully employed for the hydrosilylation and hydroboration of a vast number of ketones. The catalytic performance of 3 in the hydroboration of acetophenone exhibits a turnover frequency, reaching up to 5800 h(-)(1), outperforming that of reported zinc hydride catalysts. Notably, both intra- and intermolecular chemoselective hydrosilylation and hydroboration reactions have been investigated.

Safety of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Sahoo, RK; Mahato, M; Jana, A; Nembenna, S or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem