Category: 100-19-6

An article Chalcone derivatives bearing chromen or benzo[f]chromen moieties: Design, synthesis, and evaluations of anti-inflammatory, analgesic, selective COX-2 inhibitory activities WOS:000471750200009 published article about BIOLOGICAL EVALUATION; MOLECULAR DOCKING; AGENTS SYNTHESIS; IN-VITRO; ANALOGS; ESTERS in [Fu, Zhi-Yang; Qu, Yu-Le; Guan, Li-Ping] Zhejiang Ocean Univ, Food & Pharm Coll, Zhoushan 316022, Zhejiang, Peoples R China; [Jin, Qing-Hao] Zhejiang Ocean Univ, Donghai Sci & Technol Coll, Zhoushan 316000, Zhejiang, Peoples R China in 2019.0, Cited 28.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

Thirty-eight chalcone derivatives bearing a chromen or benzo[f]chromen moiety were synthesized and evaluated for their anti-inflammatory and analgesic activities. Using an ear edema model, anti-inflammatory activities were observed for compounds 3a-3s (ear inflammation: 1.75-3.71 mg) and 4a-4s (ear inflammation: 1.71-4.94 mg). All compounds also displayed analgesic effects with inhibition values of 66.7-100% (3a-3s) and 96.2-100% (4a-4s). The 12 compounds that displayed excellent anti-inflammatory and analgesic effects were tested for their inhibitory activity against ovine COX-1 and COX-2. Six compounds bearing a chromen moiety were weak inhibitors of the COX-1 isozyme but showed moderate COX-2 isozyme inhibitory effects (IC(50)s from 0.37 mu M to 0.83 mu M) and COX-2 selectivity indexes (SI: 22.49-9.34). Those bearing a benzo[f]chromen moiety were more selective toward COX-2 than those bearing a chromen moiety with IC(50)s from 0.25 mu M to 0.43 mu M and COX-2 selectivity indexes from SI: 31.08 to 20.67.

SDS of cas: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about 2 DISCRETE NITRILES; SUBSTITUTED PYRIMIDINE; 2+2+2 CYCLOADDITIONS; COORDINATION ARRAYS; MECHANISTIC DETAILS; ANTITUMOR-ACTIVITY; COUPLING REACTIONS; IN-VITRO; DERIVATIVES; DESIGN, Saw an article supported by the . Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Ding, YX; Ma, RC; Hider, RC; Ma, YM. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Formula: C8H7NO3

A facile and general synthesis of 2,4,6-triaryl pyrimidines has been developed. It involves a one-pot [2+1+1+1+1] pseudo five-component annulation of one methyl ketone, two aldehydes and two NH4OAc catalyzed by TfOH. One C-C and four C-N bonds are formed during the oxidative annulation process. The reaction shows good tolerance of many important functional groups in air and produces only water as the coproduct, making this methodology a highly versatile alternative to the existing methods for structuring pyrimidine framework.

Formula: C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Shan, JX; Sun, XQ; Zheng, SY; Wang, TD; Zhang, XW; Li, GZ in [Shan, Jianxing; Sun, Xiaoqing; Zheng, Shuyi; Wang, Tengda; Zhang, Xiangwen; Li, Guozhu] Tianjin Univ, Sch Chem Engn & Technol, Key Lab Green Chem Technol, Minist Educ, Tianjin 300072, Peoples R China; [Zhang, Xiangwen; Li, Guozhu] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China published Graphitic N-dominated nitrogen-doped carbon nanotubes as efficient metal-free catalysts for hydrogenation of nitroarenes in 2019.0, Cited 52.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A series of metal-free N-doped carbon nanotubes (NCNTs) are synthesized using melanin or protoporphyrin IX as the dopant via a pyrolysis process. Multiwalled carbon nanotubes with various diameters are employed as the support, and their performance is compared with those of graphene and carbon black. The content of doped graphitic N is effectively controlled by varying the heating rate during pyrolysis. The obtained metal-free catalysts are employed to catalyze the hydrogenation of various nitroarenes under mild reaction conditions (2 MPa of H-2, 120 degrees C). Efficient and selective hydrogenation of 14 nitroarenes is achieved over NCNTs with outer diameters of <= 20 nm synthesized via pyrolysis of melanin at 800 degrees C. Graphitic N in the as-prepared NCNTs is found to play a key role in efficient hydrogenation. Kinetic data reveal that a zero-order reaction occurs on the NCNTs, and the apparent activation energy of 4-nitrophenol hydrogenation is as low as 35.69 kJ mol(-1). Recycling experiments indicate that the NCNTs have good stability and recyclability for hydrogenation of 4-nitrophenol. (c) 2019 Elsevier Ltd. All rights reserved. Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Shan, JX; Sun, XQ; Zheng, SY; Wang, TD; Zhang, XW; Li, GZ or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Scissoring Enaminone C=C Double Bond by Free Radical Process for the Synthesis of alpha-Trifluoromethyl Ketones with CF3SO2Na WOS:000606840200105 published article about METAL-FREE SYNTHESIS; FACILE SYNTHESIS; OXIDATIVE TRIFLUOROMETHYLATION; MEDIATED TRIFLUOROMETHYLATION; ENOL ACETATES; CF3 RADICALS; CLEAVAGE; FLUORINATION; MIGRATION; CATALYSIS in [Gan, Lu; Yu, Qing; Liu, Yunyun; Wan, Jie-Ping] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China; [Gan, Lu] Nanchang Inst Technol, Sch Sci, Nanchang 330029, Jiangxi, Peoples R China in 2021.0, Cited 66.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. HPLC of Formula: C8H7NO3

The C=C double bond cleavage on tertiary enaminones, enabling the formation of a new C-CF3 bond, has been realized as a practical method for the synthesis of alpha-trifluoromethyl ketones with only the promotion of TBHP and ambient heating. Control experiments support that the reactions proceed via a featured free radical process. The deuterium labeling experiment employing D2O indicates that water participated in the product formation by donating the hydrogen atom for the newly generated alpha-C-H bond in the product.

HPLC of Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Gan, L; Yu, Q; Liu, YY; Wan, JP or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. Recently I am researching about ALKALINE-PHOSPHATASE; BIOLOGICAL EVALUATION; PHOSPHODIESTERASE-I; DERIVATIVES; PROTEIN; IDENTIFICATION; AGENTS; CALCIFICATION; LOCALIZATION; THIAZOLES, Saw an article supported by the Higher Education Commission of PakistanHigher Education Commission of Pakistan; DAAD (Programm Deutsch-Pakistanische Hochschulzusammenarbeit); Organization for the Prohibition of Chemical Weapons (OPCW), The Hague, The NetherlandsNetherlands Government; Higher Education Commission of PakistanHigher Education Commission of Pakistan [20-3733/NRPU/RD/14/520]; Canadian Institutes of Health ResearchCanadian Institutes of Health Research (CIHR); Fonds de recherche du Quebec-Sante (FRQS). Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Andleeb, H; Hameed, S; Ejaz, SA; Khan, I; Zaib, S; Lecka, J; Sevigny, J; Iqbal, J. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

With the aim to discover novel, efficient and selective inhibitors of human alkaline phosphatase and nucleotide pyrophosphatase enzymes, two new series of pyrazolyl pyrimidinetriones (PPTs) (6a-g) and thioxopyrimidinediones (PTPs) (6h-n) were synthesized in good chemical yields using Knoevenagel condensation reaction between pyrazole carbaldehydes (4a-g) and pharmacologically active N-alkylated pyrimidinetrione (5a) and thioxopyrimidinedione (5b). The inhibition potential of the synthesized hybrid compounds was evaluated against human alkaline phosphatase (h-TNAP and h-IAP) and ectonucleotidase (h-NPP1 and h-NPP3) enzymes. Most of the tested analogs were highly potent with a variable degree of inhibition depending on the functionalized hybrid structure. The detailed structure-activity relationship (SAR) of PPT and PTP derivatives suggested that the compound with unsubstituted phenyl ring from PPT series led to selective and potent inhibition (6a; IC50= 0.33 +/- 0.02 mu M) of h-TNAP, whereas compound 6c selectively inhibited h-IAP isozyme with IC50 value of 0.86 +/- 0.04 mu M. Similarly, compounds 6b and 6h were identified as the lead scaffolds against h-NPP1 and h-NPP3, respectively. The probable binding modes for the most potent inhibitors were elucidated through molecular docking analysis. Structure-activity relationships, mechanism of action, cytotoxic effects and druglikeness properties are also discussed.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 CHEMCATCHEM published article about COPPER-BASED ELECTROCATALYST; SELECTIVE HYDROGENATION; TANDEM CATALYSIS; OXIDE CATALYSTS; NITRO-COMPOUNDS; REDUCTION; NANOPARTICLES; GRAPHENE; DEHYDROGENATION; EFFICIENT in [Du, Jialei; Xia, Hehuan; Wang, Fang; Zhou, Weijia] Univ Jinan, Inst Adv Interdisciplinary Res, Collaborat Innovat Ctr Technol & Equipment Biol D, Jinan 250022, Shandong, Peoples R China; [Chen, Jie; Wang, Bin] Univ Jinan, Sch Chem & Chem Engn, Jinan 250022, Shandong, Peoples R China; [Zhao, Yiwei; Liu, Hong] Shandong Univ, State Key Lab Crystal Mat, Jinan 250100, Shandong, Peoples R China in 2020.0, Cited 41.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

Tandem ammonia borane dehydrogenation and nitroarenes hydrogenation has been reported as a novel strategy for the preparation of aromatic amines. However, the practical application of this strategy is subjected to the high-cost and tedious preparation of supported noble metal nanocatalysts. The commercially available CuO powder is herein demonstrated to be a robust catalyst for hydrogenation of nitroarenes using ammonia borane as a hydrogen source under mild conditions. Numerous amines (even sterically hindered, halogenated, and diamines) could be obtained through this method. This monometallic catalyst is characteristic of support-free, excellent chemoselectivity, low-cost, and high recyclability, which will favor its future utilization in preparative reduction chemistry. Mechanistic studies are also carried out to clarify that diazene and azoxybenzene are key intermediates of this heterogeneous reduction.

Recommanded Product: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Du, JL; Chen, J; Xia, HH; Zhao, YW; Wang, F; Liu, H; Zhou, WJ; Wang, B or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. In 2019.0 ACTA CRYSTALLOGR C published article about SOLVENT-FREE SYNTHESIS; ATOM-ATOM BONDS; HYDROXY PHOSPHONATES; INTERMOLECULAR INTERACTIONS; ORGANOPHOSPHORUS CHEMISTRY; ANTIOXIDANT ACTIVITY; ADDITION-REACTIONS; ACID; CONVENIENT; ESTERS in [Radai, Zita; Kiss, Nora Zsuzsa; Czugler, Matyas; Keglevich, Gyoergy] Budapest Univ Technol & Econ, Dept Organ Chem & Technol, H-1521 Budapest, Hungary; [Czugler, Matyas] Hungarian Acad Sci, Res Ctr Nat Sci, H-1525 Budapest, Hungary; [Karaghiosoff, Konstantin] Ludwig Maximilians Univ Munchen, Dept Chem & Biochem, D-81377 Munich, Germany in 2019.0, Cited 69.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The crystal structures of seven alpha-aryl-alpha-hydroxyphosphonates synthesized by the Pudovik reaction of substituted benzaldehydes and dialkyl phosphites, namely dimethyl [(hydroxy)(phenyl)methyl] phosphonate, C9H13O4P, dimethyl [(3,4-dimethoxyphenyl)(hydroxy)methyl]phosphonate, C11H17O6P, dimethyl (1-hydroxy-1-phenylethyl) phosphonate, C10H15O4P, dimethyl [1-hydroxy-1-(4-nitrophenyl)ethyl]phosphonate, C10H14NO6P, dibenzyl [hydroxy(2-nitrophenyl)methyl]phosphonate, C21H20NO6P, dibenzyl [(3-chlorophenyl)(hydroxy)methyl]phosphonate, C21H20ClO4P, and dibenzyl [hydroxy(4-methylphenyl)methyl]phosphonate, C22H23O4P, were studied to gain a better understanding of the organization in this type of molecule in the solid state. The crystals obtained for this series of compounds show a balance between C-OH center dot center dot center dot O-P chain-linked packing and the dimeric types of hydrogen-bond bridges of intermolecular pairs of such functions. The description is based on primary graph-set descriptors. Using graph-set descriptors one level deeper (i.e. secondary graph sets of the C-H center dot center dot center dot O type) revealed a similarity in the graph-set descriptors, suggesting a fine interplay of substituent- and shape-dependent effects on strong-weak interactions. It seems that the formation of chains or dimers is governed not only by the presence of a tertiary C alpha atom, but also by the nature and crowding of the ortho substituents of the alpha-aryl group.

SDS of cas: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Synthesis of 1,4-Benzothiazines via KI/DMSO/O-2-Mediated Three-Component Oxidative Cyclization/Coupling published in 2020. COA of Formula: C8H7NO3, Reprint Addresses Zhao, JW; Xu, JX (corresponding author), Guangdong Med Univ, Sch Pharm, Dongguan 523808, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A three-component transition-metal-free aerobic method for the generation of 1,4-benzothiazines is reported herein. The KI/DMSO/O-2 system was found to be effective for the oxidative cyclization/coupling of 2-aminobenzenethiols, anilines, and methylketones. Hence, various structurally important imino 1,4-benzothiazines were assembled with broad functional group tolerance. Mechanistic studies revealed an initial oxidation of ketone alpha C-H bonds by the KI/DMSO/O-2 oxidative system.

Welcome to talk about 100-19-6, If you have any questions, you can contact Zhao, JW; Luo, ZG; Xu, JX or send Email.. COA of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Tran, AV; Nguyen, TTH; Nguyen, TT; Lee, HJ; Baek, J; Kim, YJ in [Tran, Anh Vy; Huynh Nguyen, Thuy Tram; Nguyen, Thanh Tung; Lee, Hye Jin; Kim, Yong Jin] Korea Univ Sci & Technol UST, Dept Green Proc & Syst Engn, 89 Yangdaegiro Gil, Ipjang Myeon 31056, Cheonan, South Korea; [Baek, Jayeon; Kim, Yong Jin] Korea Inst Ind Technol, Green Chem & Mat Grp, 89 Yangdaegiro Gil, Cheonan Si 31056, South Korea published An Escape from Noble Metals for Generating Urethanes via Reductive Carbonylation of Nitroarenes over FeSe2/gamma-Al2O3 dagger in 2020.0, Cited 57.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The reaction of FeCl3, SeO2, and Pyridine (Py) in the presence of methanol (MeOH) under CO pressure generates a black precipitate, which has been confirmed as ferric di-selenide, FeSe2 through different structure characterization methods. Furthermore, impregnation of 5 wt% of FeSe2 onto gamma-Al2O3 exhibits better catalytic performance than FeSe2 due to the highly dispersed and smaller particle sizes ca. 200-300 nm. The reductive carbonylation of nitrobenzene (NB) was investigated over FeSe2/gamma-Al2O3 as a heterogeneous catalyst, delivering an excellent yield and high selectivity of methyl-N-phenyl carbamate (MPC). Moreover, a set of reactions was performed with variation in the reaction time, temperature, and pressure to investigate the effects of these factors. In particular, FeSe2/gamma-Al2O3 is highly stable and can be recycled for up to five cycles without significant loss in catalytic performance. A mechanistic study was also conducted on this low-cost catalyst system, especially proposing a crucial role of FeSe2 (mu-CO) active species.

Computed Properties of C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. Shaabani, A; Sepahvand, H; Ghasemi, S in [Shaabani, Ahmad; Sepahvand, Heshmatollah; Ghasemi, Shima] Shahid Beheshti Univ, Dept Chem, POB 19396-4716, Tehran, Iran published Ammonium chloride-catalyzed green multicomponent synthesis of dihydropyrazine and tetrahydrodiazepine derivatives on water in 2019.0, Cited 51.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

This research describes a simple and efficient one-pot synthetic approach for the preparation of tetrahydrodiazepine and dihydropyrazine (or dihydroquinoxaline) derivatives in high yields in the presence of a substoichiometric amount of ammonium chloride as a green accelerator on water at 50 degrees C within 1-3 h. [GRAPHICS] .

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shaabani, A; Sepahvand, H; Ghasemi, S or concate me.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem