Category: 100-19-6

An article Transition Metal Oxide-Modified Ir Nanoparticles Supported on SBA-15 Silica for Selective Hydrogenation of Substituted Nitroaromatics WOS:000677582900072 published article about CHEMOSELECTIVE HYDROGENATION; CATALYTIC-SYSTEM; CARBON; FE; NITROBENZENE; EFFICIENCY; OXIDATION; ANILINE; SIZE; THIN in [Wu, Chunzheng] Zhejiang A&F Univ, Coll Sci, Hangzhou 311300, Zhejiang, Peoples R China; [Yu, Hongbo; Wang, Shiwei; Li, Tong; Yin, Hongfeng] Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, Ningbo 315201, Zhejiang, Peoples R China in 2021.0, Cited 46.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Modification of active metals with metal oxide modifiers has attracted considerable attention in heterogeneous catalysis due to their synergistic effect. However, a controllable synthesis of highly reactive and stable metal-metal oxide hybrid nanocatalysts is difficult. To solve this problem, presynthesized IrM (M = Fe, Co, and Ni) bimetallic nanoparticles were initially confined in the mesopores of SBA-15 and were then in situ transformed to Ir-MOx hybrids. The obtained Ir-MOx/SBA-15 nanocatalysts show superior activity and selectivity in the hydrogenation of substituted nitroaromatics to corresponding aromatic amines compared to Ir/SBA-15. Among these Ir-based catalysts, Ir-FeOx/SBA-15 exhibits the highest activity and selectivity and has a wider substrate scope due to the interaction between Ir and FeOx. Therefore, our research provides a way to design reactive and stable hydrogenation catalysts.

Welcome to talk about 100-19-6, If you have any questions, you can contact Yu, HB; Wu, CZ; Wang, SW; Li, T; Yin, HF or send Email.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Transfer Hydrogenation of Ketones and Imines with Methanol under Base-Free Conditions Catalyzed by an Anionic Metal-Ligand Bifunctional Iridium Catalyst published in 2020.0, Reprint Addresses Li, F (corresponding author), Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

An anionic iridium complex [Cp*Ir(2,2′-bpyO)(OH)][Na] was found to be a general and highly efficient catalyst for transfer hydrogenation of ketones and imines with methanol under base-free conditions. Readily reducible or labile substituents, such as nitro, cyano, and ester groups, were tolerated under present reaction conditions. Notably, this study exhibits the unique potential of anionic metal-ligand bifunctional iridium catalysts for transfer hydrogenation with methanol as a hydrogen source.

Welcome to talk about 100-19-6, If you have any questions, you can contact Wang, RZ; Han, XY; Xu, J; Liu, P; Li, F or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. Liu, CJ; Mei, M; Zang, LM; Zhou, HF; Huang, XH; Wei, C in [Liu, Chanjuan; Mei, Mei; Zang, Limin; Zhou, Huanfu; Huang, Xiaohua; Wei, Chun] Guilin Univ Technol, Collaborat Innovat Ctr Explorat Hidden Nonferrous, Key Lab New Proc Technol Nonferrous Met & Mat, Minist Educ,Sch Mat Sci & Engn, Guilin 541004, Peoples R China published Highly Thermally Stable, Organosoluble, and Hydrophobic Polyimides with Pyrrolidinylphenyl Pendant Groups and Pyridine Units in 2019.0, Cited 37.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A novel diamine monomer, 4-{4-(1-pyrrolidinyl)phenyl}-2,6-bis(4-aminophenyl) pyridine (PPAP), was synthesized using 4-(1-pyrrolidinyl)benzaldehyde as starting material, and a series of aromatic polyimides were prepared using PPAP and five aromatic dianhydrides by a two-step imidization method. The structure and properties of as-prepared polyimides were studied by Fourier transform infrared spectrometer (FTIR), nuclear magnetic resonance (NMR), thermogravimetric analysis (TG), differential scanning calorimetry (DSC), and wide angle X-ray diffraction (WAXD). The results indicated that these polymers had good solubility in highboiling organic solvents upon heating, such as N,N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and N-methyl-2-pyrrolidone (NMP). Furthermore, they had outstanding thermal properties with the glass transition temperature (T-g) exceeding 354 degrees C, as well as T-5% and T-10% mass loss temperature under a nitrogen atmosphere in the range of 521534 oC and 544594 oC, respectively. Moreover, they exhibited excellent hydrophobic properties with the contact angles ranging from 82.7 to 90.5 degrees. In addition, the results of WAXD showed that these polyimides exhibited the structure of amorphous polymers.

Recommanded Product: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about N-TOSYLHYDRAZONES; ENANTIOSELECTIVE SYNTHESIS; SULFONYL HYDRAZONES; SIMPLE OLEFINS; BOND-CLEAVAGE; CONSTRUCTION; HETEROCYCLES; DERIVATIVES; ROUTE; ISOCYANIDES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21901124]; Jiangsu University Natural Science Research Program [19KJB150032, 19KJB610013]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2019M651809]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Feng, JJ; He, TT; Xie, YX; Yu, Y; Baell, JB; Huang, F. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Computed Properties of C8H7NO3

A facile and efficient strategy for the synthesis of 1,4-dihydropyridazines and pyridazines through I-2-promoted [4 + 2] cycloaddition of in situ generated azoalkenes with enaminones has been developed. The switch in selectivity is attributed to the judicious choice of different reaction temperatures. The key features of this work include controllable and selective synthesis, good functional group tolerance, good to excellent reaction yields, metal/base-free conditions, and also applicability to one-pot methodology.

Welcome to talk about 100-19-6, If you have any questions, you can contact Feng, JJ; He, TT; Xie, YX; Yu, Y; Baell, JB; Huang, F or send Email.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about TARGETING TUBULIN; DISCOVERY; ANALOGS; AFFINITY; SERIES, Saw an article supported by the Mashhad university of medical sciences. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Oskuei, SR; Mirzaei, S; Jafari-Nik, MR; Hadizadeh, F; Eisvand, F; Mosaffa, F; Ghodsi, R. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Novel imidazole-chalcone derivatives were designed and synthesized as tubulin polymerization inhibitors and anticancer agents. The antiproliferative activity of the imidazole-chalcone was assessed on some human cancer cell lines including A549 (adenocarcinoma human alveolar basal epithelial cells), MCF-7 (human breast cancer cells), MCF-7/MX (mitoxantrone resistant human breast cancer cells), and HEPG2 (human hepatocellular carcinoma cells). Generally, the imidazole-chalcone derivatives exhibited more cytotoxicity on A549 cancer cells in comparison to the other three cell lines, among them compounds 9j’ and 9g showed significant cytotoxicity with IC50 values ranging from 7.05 to 63.43 mu M against all the four human cancer cells. The flow cytometry analysis of A549 cancer cells treated with 9g and 9j’ displayed that these compounds induced cell cycle arrest at the G2/M phase at low concentrations and increased the number of apoptotic cells (cells in subG1 phase) at higher concentrations. They have also inhibited tubulin polymerization similar to combretastatin A-4 (CA-4). Annexin V binding staining assay in A549 cancer cells revealed that compound 9j’ induced apoptosis (early and late). Finally, molecular docking studies of 9j’ into the colchicine-binding site of tubulin presented the probable interactions of these compounds with tubulin.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Iodine-Mediated Nucleophilic Direct Oxidative alpha-Acetoxylation and alpha-Alkoxylation of Ketones WOS:000498739900019 published article about ENOL ETHERS; TERMINAL ALKYNES; HIGHLY EFFICIENT; IODINATION; HYDROXYLATION in [Pogaku, Naresh; Krishna, Palakodety Radha; Prapurna, Y. Lakshmi] CSIR, Indian Inst Chem Technol, Discovery Lab, Organ Synth & Proc Chem Div, D-207, Hyderabad 500007, Andhra Pradesh, India; [Pogaku, Naresh] Acad Sci & Innovat Res AcSIR, New Delhi 110025, India in 2019.0, Cited 39.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A general and facile approach for the direct alpha-functionalization of ketones mediated by iodine is developed. The operational simplicity, easily available starting materials, mild reaction conditions and tolerance of wide range of functional groups are the major benefits of the reaction.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Structural and femtosecond third-order nonlinear optical properties of electron donor- acceptor substituted chalcones: An experimental and computational approach WOS:000569382300005 published article about MOLECULAR-STRUCTURE; 1ST-ORDER HYPERPOLARIZABILITY; 1ST HYPERPOLARIZABILITY; FT-RAMAN; PROP-2-EN-1-ONE; DERIVATIVES; CRYSTAL; DFT; LI; ABSORPTION in [Patil, Parutagouda Shankaragouda; Gummagol, Neelamma B.; Ekbote, Anusha; Maidur, Shivaraj R.] KLE Inst Technol, Dept Phys, Hubballi 580030, Karnataka, India; [Ekbote, Anusha] KLSs Gogte Inst Technol, Dept Phys, Belagavi 590010, Karnataka, India; [Wong, Qin Ai; Quah, Ching Kheng] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George Town 11800, Malaysia; [Shkir, Mohd] King Khalid Univ, Fac Sci, Dept Phys, Adv Funct Mat & Optoelect Lab AFMOL, POB 9004, Abha 61413, Saudi Arabia; [Rao, S. Venugopal] Univ Hyderabad, Adv Ctr Res High Energy Mat ACRHEM, Hyderabad 500046, India in 2020.0, Cited 68.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. COA of Formula: C8H7NO3

Structural and third-order nonlinear optical (NLO) properties of two D-pi-A-pi-A [(2E)-3-(3-chlorophenyl)-1-(3-nitrophenyl)prop-2-en-1-one (3C3NC) and (2E)-3-(4-fluorophenyl)-1-(4-nitrophe nyl)prop-2-en-1-one (FNC)] and one D-pi-A-pi-D [(2E)-1-(9-anthryl)-3-(4-fluorophenyl) prop-2-en-1-one (FANC)] type chalcone derivatives were investigated experimentally as well as theoretically. All the three chalcones are centrosymmetric (CS) and crystallized in P2(1)/c space group. In crystal packing, all compounds exhibit CeH center dot center dot center dot O hydrogen bonds and pi center dot center dot center dot pi interactions. From UV-Vis-NIR absorption spectra, the cut-off wavelength and optical band gaps of the chalcones were evaluated. The thermal stability and the melting point of the chalcones were determined from the TGA/DTA techniques. The ultrafast third-order NLO properties of the three chalcones in solution (0.01 M) were evaluated by Z-scan technique using femtosecond (fs) pulses from Ti: Sapphire laser (similar to 150 fs, 80 MHz, 800 nm). Third-order nonlinear absorption (NLA) coefficient (beta similar to 10(-9) cmW(-1)), nonlinear refraction (NLR) index (n(2)similar to 10(-14) cm(2)W(-1)), susceptibility (chi((3)) similar to 10(-12) esu) and molecular hyperpolarizability (gamma(h) similar to 10(-31) esu) were unambiguously determined. The chalcones satisfy the condition to observe reverse saturable absorption (RSA) mechanism (sigma(ex) > sigma(g)). Further, the larger values of sigma(ex)/sigma(g) (similar to 2-3) indicate that the chalcones would exhibit remarkable optical limiting property. The estimated optical limiting (OL) threshold values are in the order of mu J/cm(2). Further, all the chalcones have satisfied the one-photon and two-photon figures of merit conditions (W > 1 and T < 1) for the optical switching applications. In addition to experimental findings, the optimized geometry, HOMO-LUMO energy gap, NLO parameters such as electronic dipole moment, polarizability, first and second hyperpolarizabilities of all the three chalcones were determined theoretically (DFT) for different wavelength at B3LYP/6-311 thorn G (d,p) basic set. The experimentally determined second-order susceptibilities (Z-scan technique) are reasonably in agreement with the computational values (TD-DFT). The MEP surface revealed that the 3C3NC, FNC and FANC molecules have some potential sites for electrophilic and nucleophilic attack. The experimental and computational NLO data clearly suggest that the nonlinearity of chalcone molecules greatly depends on the electron donor and acceptor strengths of the substituents. Further, all the chalcones are potential materials for optical limiting and optical switching applications. (C) 2020 Elsevier B.V. All rights reserved. COA of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Patil, PS; Gummagol, NB; Ekbote, A; Wong, QA; Quah, CK; Shkir, M; Maidur, SR; Rao, SV or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about ALCOHOLS, Saw an article supported by the Department of Science and Technology-Science and Engineering Research Board (DST-SERB), New Delhi [SRG/2019/002004]; Council of Scientific and Industrial Research (CSIR) New DelhiCouncil of Scientific & Industrial Research (CSIR) – India. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Sarki, N; Goyal, V; Tyagi, NK; Puttaswamy; Narani, A; Ray, A; Natte, K. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Product Details of 100-19-6

Methanol is a potential hydrogen source and C-1 synthon, which finds interesting applications in both chemical synthesis and energy technologies. The effective utilization of this simple alcohol in organic synthesis is of central importance and attracts scientific interest. Herein, we report a clean and cost-competitive method with the use of methanol as both C-1 synthon and H-2 source for selective N-methylation of amines by employing relatively cheap RuCl3.xH(2)O as a ligand-free catalyst. This readily available catalyst tolerates various amines comprising electron-deficient and electron-donating groups and allows them to transform into corresponding N-methylated products in moderate to excellent yields. In addition, few marketed pharmaceutical agents (e. g., venlafaxine and imipramine) were also successfully synthesized via late-stage functionalization from readily available feedstock chemicals, highlighting synthetic value of this advanced N-methylation reaction. Using this platform, we also attempted tandem reactions with selected nitroarenes to convert them into corresponding N-methylated amines using MeOH under H-2-free conditions including transfer hydrogenation of nitroarenes-to-anilines and prepared drug molecules (e. g., benzocaine and butamben) as well as key pharmaceutical intermediates. We further enable one-shot selective and green syntheses of 1-methylbenzimidazole using ortho-phenylenediamine (OPDA) and methanol as coupling partners.

Product Details of 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Sarki, N; Goyal, V; Tyagi, NK; Puttaswamy; Narani, A; Ray, A; Natte, K or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article An Umpolung Oxa-[2,3] Sigmatropic Rearrangement Employing Arynes for the Synthesis of Functionalized Enol Ethers WOS:000649477300042 published article about TRANSITION-METAL-FREE; STEVENS REARRANGEMENT; CARBON-CARBON; BENZYNE; GENERATION; MULTIFUNCTIONALIZATION; CONSTRUCTION; METHODOLOGY; STRATEGIES; REACTIVITY in [Gaykar, Rahul N.; George, Malini; Guin, Avishek; Bhattacharjee, Subrata; Biju, Akkattu T.] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India in 2021.0, Cited 79.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

An oxa-[2,3] sigmatropic rearrangement involving arynes is reported featuring the umpolung of ketones, where the C = O bond polarity is reversed. The in situ-generated sulfur ylides from beta-keto thioethers and arynes undergo efficient rearrangement allowing the facile and robust synthesis of functionalized enol ethers in high yields and excellent functional group compatibility. Preliminary mechanistic studies rule out the possibility of Pummerer-type rearrangement operating in this case.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Gaykar, RN; George, M; Guin, A; Bhattacharjee, S; Biju, AT or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

COA of Formula: C8H7NO3. In 2019.0 J ENZYM INHIB MED CH published article about MONOAMINE-OXIDASE-B; HIGH-POTENCY; IN-VITRO; MAO; SCAFFOLD; DESIGN; AGENTS; IDENTIFICATION in [Secci, Daniela; Guglielmi, Paolo; D’Ascenzio, Melissa; Chimenti, Paola] Sapienza Univ Rome, Dipartimento Chim & Tecnol Farmaco, Rome, Italy; [Carradori, Simone] G DAnnunzio Univ Chieti Pescara, Dept Pharm, Via Vestini 31, I-66100 Chieti, Italy; [Petzer, Anel; Petzer, Jacobus P.] North West Univ, Sch Pharm, Pharmaceut Chem, Potchefstroom, South Africa; [Petzer, Anel; Petzer, Jacobus P.] North West Univ, Ctr Excellence Pharmaceut Sci, Potchefstroom, South Africa; [Bagetta, Donatella; Alcaro, Stefano; Ortuso, Francesco] Magna Graecia Univ Catanzaro, Dipartimento Sci Salute, Catanzaro, Italy; [Zengin, Gokhan] Selcuk Univ, Sci Fac, Dept Biol, Konya, Turkey; [D’Ascenzio, Melissa] Univ Dundee, Sch Life Sci, DArcy Thompson Unit, Dundee DD1 4HN, Scotland in 2019.0, Cited 51.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents were linked to N1 of the hydrazone in order to establish robust structure-activity relationships. The results of the biological testing demonstrated that the presence of the hydrazothiazole nucleus bearing at C4 a phenyl ring functionalised at the meta position with a nitro group represents an important pharmacophoric feature to obtain selective and reversible human MAO-B inhibition for the treatment of neurodegenerative disorders. In addition, the most potent and selective MAO-B inhibitors were evaluated in silico as potential cholinesterase (AChE/BuChE) inhibitors and in vitro for antioxidant activities. The results obtained from molecular modelling studies provided insight into the multiple interactions and structural requirements for the reported MAO inhibitory properties.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Secci, D; Carradori, S; Petzer, A; Guglielmi, P; D’Ascenzio, M; Chimenti, P; Bagetta, D; Alcaro, S; Zengin, G; Petzer, JP; Ortuso, F or concate me.. COA of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem