Category: 1762-34-1

Category: benzodioxans. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Identification of descriptors for structure-activity relationship in ruthenium (II) mixed compounds with antiparasitic activity. Author is Cedillo-Gutierrez, Erika Lorena; Hernandez-Ayala, Luis Felipe; Torres-Gutierrez, Carolina; Reina, Miguel; Flores-Alamo, Marcos; Carrero, Julio C.; Ugalde-Saldivar, Victor M.; Ruiz-Azuara, Lena.

Herein is presented the synthesis, characterization, electrochem. studies, DFT calculations and in vitro evaluation of amoebicidal activity in trophozoites of Entamoeba histolytica of twenty ruthenium(II) mixed compounds with general formulas: [Ru(pdto)(E-E)]Clx (E-E bidentate, either neutral or neg. charged ligands). For compounds under study, O-O, N-O and N-N auxiliary donor ligands demonstrate to have a crucial impact on the electronic properties and that it is possible to modulate the antiparasitic activity. Among analyzed complexes, only four present a better performance compared to typically used metronidazole drug (IC50 < 6.80μmol/L) to treat amebiasis disease. For studied compounds, structure-activity relations are strongly determined by either the redox potential (E1/2) of RuII/RuIII and calculated molar volume (V) of the complexes. I hope my short article helps more people learn about this compound(5,5'-Dimethyl-2,2'-bipyridine)Category: benzodioxans. Apart from the compound(1762-34-1), you can read my other articles to know other related compounds.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Synthesis, structural characterization and in vitro cytotoxic evaluation of mixed Cu(II)/Co(II) levofloxacin-bipyridyl complexes. Author is Bashir, Masrat; Yousuf, Imtiyaz.

This work features synthesis, structural characterization and biol. evaluation of two Cu(II)/Co(II)-based complexes (1 and 2) synthesized from levofloxacin (lvXn) and bipyridyl ligands. The structural elucidation of complexes 1 and 2 was carried out by anal., spectral (UV-vis, FTIR, EPR) and single crystal x-ray crystallog. techniques. The crystallog. details of complex 1 revealed a triclinic crystal system with P-1 space group and lattice parameters a = 10.32(7) Å, b = 11.75(8) Å, c = 14.85(9) Å, and α = 87.40°, β = 77.55°, γ = 66.26°. The DFT studies were performed to study the electronic structure and localization of HOMO and LUMO electron densities on the complexes. authors have also performed comparative in vitro DNA/BSA binding studies of complexes 1 and 2 by multispectroscopic methods to evaluate the cytotoxic potential of synthesized complexes which revealed better binding potential of copper analog. Furthermore, the cytotoxic assessment of copper analog was examined on a panel of five human cancer cell lines employing SRB assay which revealed remarkably good and selective cytotoxic activity towards A498 (kidney), HeLa (cervical) and HepG2 (hepatoma) cancer cell lines.

I hope my short article helps more people learn about this compound(5,5′-Dimethyl-2,2′-bipyridine)Category: benzodioxans. Apart from the compound(1762-34-1), you can read my other articles to know other related compounds.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 5,5′-Dimethyl-2,2′-bipyridine. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about H/D solvent isotope effects on the photoracemization reaction of enantiomeric the tris(2,2′-bipyridine)ruthenium(II) complex and its analogues. Author is Asahara, Masahiro; Kurimoto, Haruhiko; Nakamizu, Masato; Hattori, Shingo; Shinozaki, Kazuteru.

This work assessed solvent isotope effects on the photoracemization rate and emission lifetime for [Ru(bpy)3]2+ (bpy = 2,2′-bipyridine) in water. An anal. of the effects of temperature on photoracemization rate and emission lifetime demonstrated that the transition from one enantiomer to the other is unaffected by the isotopic composition of the solvent. Also deactivation from the metal-to-ligand charge-transfer (3MLCT) excited state to the ground state is responsible for the solvent isotope effect on the photoracemization rate. The photoracemization reaction proceeds via a bond-breaking mechanism. In this process, a five-coordinated species produced through breaking of the Ru-N bond in the 3d-d* state undergoes a structural change to produce an achiral five-coordinated species. An anal. of the effect of temperature on emission lifetime, excluding the activation to the 3d-d* state that leads to the structural change, showed that the solvent isotopic composition affects deactivation from the 4th MLCT state.

I hope my short article helps more people learn about this compound(5,5′-Dimethyl-2,2′-bipyridine)Quality Control of 5,5′-Dimethyl-2,2′-bipyridine. Apart from the compound(1762-34-1), you can read my other articles to know other related compounds.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C12H12N2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Syntheses, molecular structures, and spectroscopic properties of manganese(II)/(III) complexes with tetraphenylimidodiphosphinato and bi-pyridine or salicylaldehyde ligands. Author is Qian, Zhe; Zhang, Ying; Jia, Ai-Quan; Shi, Hua-Tian; Zhang, Qian-Feng.

Treatment of [Mn(CH3COO)2·4H2O] with two equivalent of K[N(Ph2PO)2] in the presence of one equivalent of 2,2′-bipyridine (bpy) or 5,5′-dimethyl-2,2′-bipyridine(dmbpy) in ethanol gave the mono-nuclear manganese(II) complexes [Mn{η1-O-N(Ph2PO)2}{N(Ph2PO)2}(EtOH)(bpy)] (1) and [Mn{N(Ph2PO)2}2(dmbpy)] (2), resp. Interaction of [Mn(CH3COO)2·4H2O], K[N(Ph2PO)2] and salicylaldehyde or 5-chlorosalicylaldehyde or 3,5-dibromosalicylaldehyde in the presence of triethylamine in methanol gave the bi-nuclear manganese(II) complexes [Mn2{N(Ph2PO)2}2(μ,η2-O,O’-Sal)2(MeOH)2] (3) and [Mn2{N(Ph2PO)2}2(μ,η2-O,O’-5-Cl-Sal)2(MeOH)2] (4), and a tetra-nuclear manganese(II)/(III) complex [Mn4{N(Ph2PO)2}2(μ,η2-O,O’-3,5-Br2-Sal’)2(MeOH)4(μ-OMe)2(μ3-OMe)2] (5), resp. All complexes were characterized by IR and UV spectroscopy, their mol. structures were unambiguously established by single crystal x-ray diffraction. The electrochem. properties of complexes 1-5 were also studied.

I hope my short article helps more people learn about this compound(5,5′-Dimethyl-2,2′-bipyridine)Formula: C12H12N2. Apart from the compound(1762-34-1), you can read my other articles to know other related compounds.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Name: 5,5′-Dimethyl-2,2′-bipyridine. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Bipyridine-Directed Syntheses of Uranyl Compounds Containing Semirigid Dicarboxylate Linkers: Diversity and Consistency in Uranyl Speciation.

Bipyridine organic bases are beneficial to the synthesis of novel uranyl-organic hybrid materials, but the relationship between their mol. structures and specific roles as structure-directing agents, especially for the semirigid dicarboxylate systems, is still unclear. Here we demonstrate how the bipyridine ligands direct the coordination assembly of uranyl-organic compounds with a semirigid dicarboxylate linker, 4,4′-dicarboxybiphenyl sulfone (H2dbsf), by utilizing a series of bipyridine ligands, 1,10-phenanthroline (phen), 2,2′-bipyridine (2,2′-bpy), 5,5′-dimethylbipyridine (5,5′-dmbpy), 4,4′-bipyridine (4,4′-bpy), or 1,3-di(4-pyridyl)propane (bpp). Under hydrothermal conditions, eight uranyl-organic coordination polymers (UCPs), four of which [[UO2(dbsf)(phen)] (1), [UO2(dbsf)(phen)]·H2O (1′), [U4O10(dbsf)3]2[H2bpp]2 (6), and [U4O10(dbsf)3]2[H2bpp] (6′)] were reported previously, were synthesized and divided into two types based on the chelate or template effect of these bipyridine ligands. 1, 1′, [UO2(dbsf)(2,2′-bpy)] (2), and [(UO2)2(dbsf)2(5,5′-dmbpy)2] (3) are springlike triple helixes with bipyridine ligands (phen, 2,2′-bpy, or 5,5′-dmbpy) as chelate ligands, while [U4O10(dbsf)3][H2(4,4′-bpy)] (4), [U4O10(dbsf)3]2[H(4,4′-bpy)]2[Ni(H2O)6] (5), 6, and 6′ are tetranuclear uranyl-mediated 2-fold-interpenetrating networks with 4,4′-bpy or bpp as template ligands and charge-balancing agents. The participation or not in uranyl coordination of different bipyridine ligands promotes not only diversity in uranyl speciation and final topol. structures among different classes of organic bases but also consistency for the same types of bipyridine ligands, which thus endows the possibility of the rational design of UCPs based on semirigid dicarboxylate ligands with the aid of cautiously selected bipyridine ligands.

I hope my short article helps more people learn about this compound(5,5′-Dimethyl-2,2′-bipyridine)Name: 5,5′-Dimethyl-2,2′-bipyridine. Apart from the compound(1762-34-1), you can read my other articles to know other related compounds.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Bridging Solution and Solid-State Chemistry of Dicyanoaurate: The Case Study of Zn-Au Nucleation Units.Reference of 5,5′-Dimethyl-2,2′-bipyridine.

The behavior in solution of the dicyanoaurate anion in the presence of other metal centers has so far been little explored, despite its importance in material science. The design and synthesis of systems with controlled coordination behavior, using chelating ligands and ZnII, has allowed us to detect self-assembly and oligomerization in solution This phenomenon has been studied with 13C and 1H NMR, absorption and emission UV-vis spectroscopy, ESI-MS, and XAS at both the Au L3-edge and Zn K-edge: all of these techniques confirm the presence of Au-Zn aggregation products. These fragments, resembling structural units in the solid state, reveal that coordination of dicyanoaurate to free sites around metal centers can occur at a lower concentration than those at which crystals start to form and at which aurophilic interactions are observed, forming the connection between solution species and solid-state architectures. Through the use of a multitechnique approach, the solution chem. of dicyanoaurate in the presence of zinc complexes has been successfully correlated to prenucleation aggregation. The difference in polarity or hydrogen bond properties of the crystallization solvent generates, in the presence of the same reagents, substantially different compounds, and these phases have been analyzed through the results obtained in solution

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Rand, Alexander W.; Yin, Hongfei; Xu, Liang; Giacoboni, Jessica; Martin-Montero, Raul; Romano, Ciro; Montgomery, John; Martin, Ruben published the article 《Dual Catalytic Platform for Enabling sp3 α C-H Arylation and Alkylation of Benzamides》. Keywords: benzamide arylation alkylation chemoselective enantioselective photoredox.They researched the compound: 5,5′-Dimethyl-2,2′-bipyridine( cas:1762-34-1 ).Related Products of 1762-34-1. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1762-34-1) here.

A dual catalytic sp3 α C-H arylation and alkylation of benzamides with organic halides is described. This protocol exhibits an exquisite site selectivity, chemoselectivity, and enantioselectivity pattern, offering a complementary reactivity mode to existing sp3 arylation or alkylations via transition metal catalysis or photoredox events.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Electric Literature of C12H12N2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Exploiting the versatility of pyridyl ligands for the preparation of diorganotin (IV) adducts: spectral, crystallographic and Hirshfeld surface analysis studies. Author is Momeni, Badri Z.; Fathi, Nastaran; Abbasi, Reyhaneh; Janczak, Jan.

Diorganotin (IV) complexes SnR2X2 (R = Me, Ph; X = Cl, NCS) form a series of versatile complexes when react with bidentate substituted pyridyl ligands. The reaction of dimethyltin dichloride with 5,5′-dimethyl-2,2′-bipyridine (5,5′-Me2bpy) resulted in the formation of [SnMe2Cl2(5,5′-Me2bpy)] (1). Moreover, the reaction of SnMe2(NSC)2 with 4,4′-di-tert-butyl-2,2′-bipyridine (bu2bpy), 1,10-phenanthroline (phen) and 4,7-diphenyl-1,10-phenanthroline (bphen) affords the hexa-coordinated complexes [SnMe2(NCS)2(bu2bpy)] (2), [SnMe2(NCS)2(phen)] (3) and [SnMe2(NCS)2(bphen)] (4), resp. The resulting complexes have been characterized using elemental anal., IR, multinuclear NMR (1H, 13C, 119Sn) and DEPT-135° NMR spectroscopy. On the other hand, the reaction of diphenyltin dichloride with 2,2′-biquinoline (biq) and 4,7-phenantroline (4,7-phen) led to the formation of polymeric complexes of [SnPh2Cl2(4,7-phen)]n (5) and [SnPh2Cl2(biq)]n (6). The NMR spectra, however, reveal the ligand lability in solution and suggest a coordination number of 5. The X-ray crystal structures of complexes [SnMe2Cl2(5,5′-Me2bpy)] (1), [SnMe2(NCS)2(bu2bpy)] (2) and [SnMe2(NCS)2(bphen)] (4) have been determined which reveal that the geometry around the tin atom is distorted octahedral with trans-[SnMe2] configuration. Interestingly, the crystal structure of (H2biq)2[SnPh2Cl4]•2CHCl3 (7) was characterized by X-ray crystallog. from a chloroform solution of [SnPh2Cl2(biq)]n (6) indicating the formation of doubly protonated [H2biq]+ and [Ph2SnCl4]2- which are stabilized by a network of hydrogen bonds with a feature of trans-[SnPh2]. The 3D Hirshfeld surface anal. and 2D fingerprint maps were used for quant. mapping out of the intermol. interactions for 1, 2, 4 and 7 which show the presence of π-π and hydrogen bonding interactions which are associated between donor and acceptor atoms (N, S, Cl) in the solid state.

I hope my short article helps more people learn about this compound(5,5′-Dimethyl-2,2′-bipyridine)Electric Literature of C12H12N2. Apart from the compound(1762-34-1), you can read my other articles to know other related compounds.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Structure analysis and biological functionalities of a nickel(II) complex and its sonochemically synthesized nano form: in vitro anti-proliferation, DNA binding, antibacterial and molecular docking study, the main research direction is nickel methylbipyridine thiocyanate complex preparation crystal structure; DNA binding nickel methylbipyridine thiocyanate complex nanoparticle; antibacterial anticancer antioxidant activity nickel methylbipyridine thiocyanate complex.Category: benzodioxans.

A compound of {[Ni(5,5′-Dimethyl-2,2′-bipyridine)3](SCN)2}2(a) was synthesized and characterized by FTIR, UV-visible spectroscopy, elemental anal., luminescence and x-ray crystallog. The single crystals were obtained by slow crystallization from a methanol solution The complex is composed of nickel cation chelated by three neutral bipyridine ligands and two (SCN-) ions outside the coordination sphere. The nano form of the synthesized complex (b) was prepared by a sonochem. process and confirmed with XRD, SEM and FTIR. The average size of the particles was 37 nm from SEM. Thermodn. parameters (ΔH°, ΔS° and ΔG°) calculated from FS-DNA interaction of complexes showed that hydrogen bonding and van der Waals interactions have an essential function in the interaction of DNA-Ni(II) complex, and the interaction mode is groove binding. Viscosity measurement illustrated that relative viscosity of DNA remained unchanged with the adding concentrations of complexes. CD spectra showed that the structure of DNA was changed. The antibacterial properties were investigated in vitro against standard Gram-pos. and Gram-neg. bacterial strains. The results of antibacterial tests showed that (a) was a stronger antibacterial agent than the free ligand, and that the antibacterial effect of (b) was stronger than the one of (a). The cytotoxicity activity experiments against MCF-7, KB and A549 cells revealed low to moderate antiproliferative activity of the complex (b) against cancer cells. The mol. docking results exhibited groove mode of binding, confirming previously obtained data from spectroscopy, viscometry and CD.

Here is just a brief introduction to this compound(1762-34-1)Category: benzodioxans, more information about the compound(5,5′-Dimethyl-2,2′-bipyridine) is in the article, you can click the link below.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Controlling the Synthesis of Metal-Organic Framework UiO-67 by Tuning Its Kinetic Driving Force, the main research direction is metalorganic framework UiO67 synthesis control tuning kinetic driving force.Synthetic Route of C12H12N2.

The successful synthesis of metal-organic framework (MOF) compounds relies on an intricate interplay between the components of the synthesis liquor at the given synthesis conditions. The interdependence of modulator, linker, and solvent amounts in the synthesis of the Zr-based MOF, UiO-67, is explored. Probably control of linker vacancy defects in UiO-67 is feasible by tuning the ratios of these components, and such control derives from recognizing the kinetic driving forces during MOF crystal growth. Linker vacancy defects (and modulator mols. occupying linker sites) can be reduced by limiting the solvent amount to maintain a saturated concentration of linker throughout the synthesis. The method enables formation of UiO-67 with an ideal 1:1 ratio between Zr and the 4,4′-biphenyldicarboxylic acid linker, without surplus linker in the mother liquor or addnl. post-synthetic steps, and reduces the amount of DMF solvent to <20% the amount in previously reported procedures. Here is just a brief introduction to this compound(1762-34-1)Synthetic Route of C12H12N2, more information about the compound(5,5′-Dimethyl-2,2′-bipyridine) is in the article, you can click the link below.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem