Research speed reading in 2021.The prevalence of solvent effects has motivated developing quantitative kinetic, spectroscopic, and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states. Recommanded Product: 2879-20-1, In a article, mentioned the application of 2879-20-1, Name is 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethanone, molecular formula is C10H10O3
The invention relates to compounds of the formula STR1 wherein R1 is hydrogen, acyl, lower-alkyl or –CHO, –CH2 OR10, –COR7 or OR13 ; R2, R3 and R4 are, independently, hydrogen, lower-alkyl, lower-alkoxy or halogen; R5 and R6 are, independently, hydrogen or lower-alkyl; R7 is hydroxy, lower-alkoxy or NR8 R9 ; R8 and R9 are, independently, hydrogen or lower-alkyl; X and Y are, independently, >CR14 R15, –O–, –S–, >SO, >SO2 or >NR18 ; R10 and R18 are, independently, hydrogen, lower-alkyl or acyl; M is –C(R11)=C(R12)–, –CONH– or –NH–CO–; R11, R12, R14 and R15 are, independently, hydrogen or lower-alkyl, R13 is hydrogen, lower-alkoxycarbonyl or lower- alkyl, which can be substituted by amino, mono-alkylamino, di-alkylamino, morpholino, thiomorpholino or piperazino; and n is 1, 2, 3 or 4; with the proviso that at least one of X and Y comprises a hetero atom and n is 1, 3 or 4 when X contains a hetero atom, Y is >C(CH3)2 and R1 is lower-alkyl or –CH2 OR10 or –COR7, or a salt of a compound of formula I, when R1 is carboxy. The compounds of formula I are useful in the treatment of prophylaxis of neoplasms, dermatoses and ageing of the skin.
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