Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 2,3-Dihydrobenzo[b][1,4]dioxin-6-amine. Introducing a new discovery about 22013-33-8, Name is 2,3-Dihydrobenzo[b][1,4]dioxin-6-amine
Straight Access to Indoles from Anilines and Ethylene Glycol by Heterogeneous Acceptorless Dehydrogenative Condensation
The development of original strategies for the preparation of indole derivatives is a major goal in drug design. Herein, we report the first straight access to indoles from anilines and ethylene glycol by heterogeneous catalysis, based on an acceptorless dehydrogenative condensation, under noninert conditions. In order to achieve high selectivity, a combination of Pt/Al2O3 and ZnO have been found to slowly dehydrogenate ethylene glycol generating, after condensation with the amine and tautomeric equilibrium, the corresponding pyrrole-ring unsubstituted indoles.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 2,3-Dihydrobenzo[b][1,4]dioxin-6-amine, you can also check out more blogs about22013-33-8
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem