COA of Formula: C14H11N. Recently I am researching about ASYMMETRIC ALPHA-ALLYLATION; ANION PHASE-TRANSFER; TSUJI-TROST REACTION; C-O BOND; TRANSITION-METAL; BRONSTED ACID; DUAL CATALYSIS; NONCOVALENT INTERACTIONS; TRANSFER HYDROGENATION; OXIDATIVE ADDITION, Saw an article supported by the National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [GM121383, R35 GM118190]; Ministry of Science and Technology, TaiwanMinistry of Science and Technology, Taiwan [106-2917-I-564-056]; EUEuropean Commission [789399]; NSFNational Science Foundation (NSF) [ACI-1548562]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Tsai, CC; Sandford, C; Wu, T; Chen, BY; Sigman, MS; Toste, FD. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile
The mode of asymmetric induction in an enantioselective intramolecular allylic substitution reaction catalyzed by a combination of palladium and a chiral phosphoric acid was investigated by a combined experimental and statistical modeling approach. Experiments to probe nonlinear effects, the reactivity of deuterium-labeled substrates, and control experiments revealed that nucleophilic attack to the pi-allylpalladium intermediate is the enantio-determining step, in which the chiral phosphate anion is involved in stereoinduction. Using multivariable linear regression analysis, we determined that multiple noncovalent interactions with the chiral environment of the phosphate anion are integral to enantiocontrol in the transition state. The synthetic protocol to form chiral pyrrolidines was further applied to the asymmetric construction of C-O bonds at fully substituted carbon centers in the synthesis of chiral 2,2-disubstituted benzomorpholines.
COA of Formula: C14H11N. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Tsai, CC; Sandford, C; Wu, T; Chen, BY; Sigman, MS; Toste, FD or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem