Heterocyclic Building Blocks-benzodioxan

Authors Bonakdar, APS; Sadeghi, A; Aghaei, HR; Beheshtimaal, K; Nazifi, SMR; Massah, AR in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about SOLVENT-FREE; ANTICANCER; EFFICIENT; INHIBITORS; CATALYST; DESIGN; ARYL in [Bonakdar, A. P. S.; Sadeghi, A.; Aghaei, H. R.; Massah, A. R.] Islamic Azad Univ, Dept Chem, Shahreza Branch, Shahreza 86145311, Iran; [Beheshtimaal, K.] Islamic Azad Univ, Dept Microbiol, Falavarjan Branch, Esfahan, Iran; [Nazifi, S. M. R.] Isfahan Univ Med Sci, Sch Pharm & Pharmaceut Sci, Dept Med Chem, Esfahan 8174673461, Iran in 2020, Cited 25. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Novel chalcone sulfonamide derivatives were synthesized starting from benzophenones and aldehydes in 3 steps. Also, (E)-3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one was converted to different pyrazoline in four steps. The synthesis of sulfonamides was carried out under solvent-free conditions at room temperature and the products were obtained in high purity after a simple work-up without using any chromatography method for purification. All of the products were evaluated for their in vitro antibacterial activity againstStaphylococcus aureusandEscherichia coli.

Safety of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Bonakdar, APS; Sadeghi, A; Aghaei, HR; Beheshtimaal, K; Nazifi, SMR; Massah, AR or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about HETEROGENEOUS CATALYST; COPPER; NANOPARTICLES; DIARYL; SUPPORT; HYBRID, Saw an article supported by the University of Kashan [256722/29]. Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Zarnegar, Z; Monjezi, HR; Safari, J. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Novel arginine-functionalized starch-based nanoparticles (Arg-SNPs) were synthesized and characterized by Fourier transforms infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX), X-ray diffraction (XRD) and thermos-gravimetric analyses (TGA) techniques. Arg-SNP was used as a highly efficient and macromolecule-supported recyclable nanocatalyst for the one-pot reaction between thiourea and iodine with various substituted methylcarbonyls to afford the corresponding diheteroaryl thioethers in high-to-quantitative yields. The nanocatalyst was recycled at least five times without significant decrease in the catalytic activity. (C) 2019 Elsevier B.V. All rights reserved.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Design, Sonosynthesis, Quantum-Chemical Calculations, and Evaluation of New Mono- and Bis-pyridine Dicarbonitriles as Antiproliferative Agents published in 2020.0, Reprint Addresses Arafa, WAA (corresponding author), Jouf Univ, Coll Sci, Chem Dept, POB 2014, Sakaka, Aljouf, Saudi Arabia.; Arafa, WAA (corresponding author), Fayoum Univ, Fac Sci, Chem Dept, POB 63514, Fayoum City, Egypt.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

i Summary of main observation and conclusion A highly efficient, simple, and clean single-step sonosynthetic procedure has been sophisticated for assembling new series of mono- and bis-pyridine dicarbonitriles from ketones, HCl, and tetracyanoethylene. The presented protocol is applicable for the preparation of a broad range of uniquely substituted pyridine dicarbonitriles and seems to be superior in comparison with other previously reported methods. The antiproliferative impact of the newly synthesized derivatives was screened towards three representative cancer cell lines (MCF-7, A549, and HCT116). Most of the evaluated derivatives showed a moderate to excellent anti-proliferative activity towards the selected cell lines. Of these, compounds 4h, 4k, 10, 12a, and 12b showed both potent anticancer activity (IC50<10 mu M) and lower cytotoxic effect (IC50 > 58 mu M) on non-tumorigenic cells (MCF-10A and NCM460), suggesting their promising potential to be lead molecules for future antitumor drug discovery. The structure-activity relationships have been also discussed. Moreover, quantum chemical studies based on Density Functional Theory (DFT) of the synthesized compounds were investigated and found to be consistent with the in vitro inhibitory activities.

Welcome to talk about 100-19-6, If you have any questions, you can contact Arafa, WAA; Hussein, MF or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. In 2019.0 J HETEROCYCLIC CHEM published article about 2-(1H-PYRAZOL-1-YL)-THIAZOLE DERIVATIVES; APOPTOSIS; INHIBITORS; CYTOTOXICITY; OPTIMIZATION; ANTICANCER; GROWTH; SAR in [Reddy, Nemallapudi Bakthavatchala; Zyryanov, Grigory V.; Reddy, Guda Mallikarjuna; Sravya, Gundala] Ural Fed Univ, Chem Engn Inst, Ekaterinburg 620002, Russia; [Reddy, Guda Mallikarjuna; Garcia, Jarem Raul] Univ Estadual Ponta Grossa, Dept Chem, BR-84030900 Ponta Grossa, Parana, Brazil; [Balakrishna, Avula] Rajeev Gandhi Mem Coll Engn & Technol Autonomous, Nandyal 518501, Andhra Pradesh, India; [Padmaja, Adivireddy; Padmavathi, Venkatapuram; Reddy, Cirandur Suresh] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India; [Zyryanov, Grigory V.] Russian Acad Sci, I Ya Postovskiy Inst Organ Synth, Ural Div, 22 S Kovalevskoy St, Ekaterinburg 620219, Russia in 2019.0, Cited 38.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A new class of bis heterocycles-benzimidazolyl pyrazoles were prepared from the Michael acceptor (E)-3-(1H-benzimidazol-2-yl)-1-aryl-prop-2-en-1-one. The thiamide group was exploited to develop thiazole ring on treatment with p-fluorophenacyl bromide to get tris heterocycles. All the lead compounds were tested for antimicrobial activity. The compound 7d having nitro substituent on the aromatic ring showed greater antimicrobial activity particularly against Pseudomonas aeruginosa and Penicillium chrysogenum.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Huang, XH; Li, H; Liu, CJ; Wei, C in SAGE PUBLICATIONS LTD published article about AROMATIC POLYIMIDES; TRANSPARENT; SOLUBILITY in Guilin Univ Technol, Minist Educ, Key Lab New Proc Technol Nonferrous Met & Mat, Guilin, Peoples R China; Guilin Univ Technol, Sch Mat Sci & Engn, Guilin, Peoples R China in 2019.0, Cited 38.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In this study, a novel diamine monomer, 4-(4-trifluoromethylthiophenyl)-2,6-bis(4-aminophenyl)pyridine (FTPAP) was synthesized through two-step reaction from 4-trifluoromethylthiobenzaldehyde and 4-nitroacetophenone as raw materials, and then the structure of FTPAP was characterized by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance, and mass spectrometry. A series of fluorinated polyimides were prepared from FTPAP with five commercial dianhydrides, namely, pyromellitic dianhydride, biphenyl tetracarboxylic dianhydride, oxydiphtahalic anhydride, benzophenone tetracarboxylic dianhydride, and 4,4 ‘-(hexafluoroisopropylidene) diphthalic anhydride. The structure and performance of the fluorinated polymers were fully characterized by FTIR, differential scanning calorimetry, thermogravimetric analysis, and wide-angle X-ray diffraction (WAXD). The inherent viscosity of polymers ranged from 0.41 to 1.45 dL g(-1). These polymers displayed good solubility in polar aprotic solvents, such as N,N-dimethylformamide, N,N-dimethylacetamide, dimethyl sulfoxide, and N-methyl-2-pyrrolidone, at room temperature or on heating. Furthermore, they exhibited outstanding thermal stability with glass transition temperatures beyond 305 degrees C, and the temperature of 10% weight loss was in the range of 514-573 degrees C with more than 56% residue at 800 degrees C under nitrogen. Moreover, they showed high optical transparency with the cutoff wavelengths in the range of 385-457 nm and excellent hydrophobic property with contact angle in the range of 82.8-97.6 degrees. In addition, the results of WAXD indicated that all of the polymers presented amorphous structure.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Huang, XH; Li, H; Liu, CJ; Wei, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Probing the high potency of pyrazolyl pyrimidinetriones and thioxopyrimidinediones as selective and efficient non-nucleotide inhibitors of recombinant human ectonucleotidases WOS:000475378400004 published article about ALKALINE-PHOSPHATASE; BIOLOGICAL EVALUATION; PHOSPHODIESTERASE-I; DERIVATIVES; PROTEIN; IDENTIFICATION; AGENTS; CALCIFICATION; LOCALIZATION; THIAZOLES in [Andleeb, Hina; Hameed, Shahid; Khan, Imtiaz] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan; [Andleeb, Hina] Int Islamic Univ, Fac Basic & Appl Sci, Sulaiman Bin Abdullah Aba Al Khail Ctr Interdisci, Islamabad, Pakistan; [Ejaz, Syeda Abida; Zaib, Sumera; Iqbal, Jamshed] COMSATS Inst Informat Technol, Ctr Adv Drug Res, Abbottabad 22060, Pakistan; [Khan, Imtiaz] Univ Manchester, Sch Chem, Oxford Rd, Manchester M13 9PL, Lancs, England; [Khan, Imtiaz] Univ Manchester, Manchester Inst Biotechnol, 131 Princess St, Manchester M1 7DN, Lancs, England; [Lecka, Joanna; Sevigny, Jean] Univ Laval, Fac Med, Dept Microbiol Infectiol & Immunol, Quebec City, PQ G1V 0A6, Canada; [Lecka, Joanna; Sevigny, Jean] Univ Laval, CHU Quebec, Ctr Rech, Quebec City, PQ G1V 4G2, Canada in 2019.0, Cited 52.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

With the aim to discover novel, efficient and selective inhibitors of human alkaline phosphatase and nucleotide pyrophosphatase enzymes, two new series of pyrazolyl pyrimidinetriones (PPTs) (6a-g) and thioxopyrimidinediones (PTPs) (6h-n) were synthesized in good chemical yields using Knoevenagel condensation reaction between pyrazole carbaldehydes (4a-g) and pharmacologically active N-alkylated pyrimidinetrione (5a) and thioxopyrimidinedione (5b). The inhibition potential of the synthesized hybrid compounds was evaluated against human alkaline phosphatase (h-TNAP and h-IAP) and ectonucleotidase (h-NPP1 and h-NPP3) enzymes. Most of the tested analogs were highly potent with a variable degree of inhibition depending on the functionalized hybrid structure. The detailed structure-activity relationship (SAR) of PPT and PTP derivatives suggested that the compound with unsubstituted phenyl ring from PPT series led to selective and potent inhibition (6a; IC50= 0.33 +/- 0.02 mu M) of h-TNAP, whereas compound 6c selectively inhibited h-IAP isozyme with IC50 value of 0.86 +/- 0.04 mu M. Similarly, compounds 6b and 6h were identified as the lead scaffolds against h-NPP1 and h-NPP3, respectively. The probable binding modes for the most potent inhibitors were elucidated through molecular docking analysis. Structure-activity relationships, mechanism of action, cytotoxic effects and druglikeness properties are also discussed.

Welcome to talk about 100-19-6, If you have any questions, you can contact Andleeb, H; Hameed, S; Ejaz, SA; Khan, I; Zaib, S; Lecka, J; Sevigny, J; Iqbal, J or send Email.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 2,2-Diphenylacetonitrile. I found the field of Chemistry very interesting. Saw the article Olefin Oxyamination with Unfunctionalized N-Alkylanilines published in 2019, Reprint Addresses Niggeman, M (corresponding author), Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany.. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile.

N-Alkylanilines have rarely been used in oxyamination reactions, due to the normally necessary pre-functionalization of the N-atom. Also, the formation of aminium radical cations (ARCs) of anilines bearing alkyl substituents is plagued by the ARC’s tendency to instantaneously convert to alpha-amino radicals or iminium ions. We present a readily available reagent combination that addresses both challenges, and thus allows for an oxyamination with N-alkylanilines via ARCs as the crucial reactive intermediates and excellent diastereoselectivity.

Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.. Safety of 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 GREEN CHEM published article about PHASE DEHYDRATION; SOLID ACID; DIRECT CONVERSION; SOLVENT; CELLULOSE; EFFICIENT; WATER; ETHERIFICATION; ESTERIFICATION; TRANSFORMATION in [Du, Yi-Ran; Xu, Bao-Hua; Pan, Jia-Sheng; Wang, Yao-Feng; Zhang, Suo-Jiang] Chinese Acad Sci, Beijing Key Lab Ion Liquids Clean Proc, CAS Key Lab Green Proc & Engn, State Key Lab Multiphase Complex Syst,Inst Proc E, Beijing 100190, Peoples R China; [Du, Yi-Ran; Xu, Bao-Hua; Zhang, Suo-Jiang] Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China; [Pan, Jia-Sheng] East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China; [Wu, Yi-Wei; Peng, Xiao-Ming] Beijing Inst Petrochem Technol, Beijing Key Lab Clean Fuel & Efficient Catalyt Re, Beijing 102617, Peoples R China in 2019.0, Cited 59.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

The confinement of Bronsted acidic 1-methyl-3-(3-sulfopropyl)-1H-imidazol-3-ium hydrosulfate ([PSMIm][HSO4]) into the channel walls of two-dimensional (2D) COFs using a one-pot self-assembly strategy was achieved by incorporating an imine-linked TPB-DMTP-COF (TPB, triphenylbenzene; DMTP, dimethoxyterephthaldehyde) as the host. An appropriate loading of [PSMIm][HSO4] is crucial for the BIL-COF hybrids to maintain proper geometry in the channel and sufficient acidic sites for the sorbitol substrate and sorbitan intermediate to enter and react. The best yield of isosorbide (97%) from sorbitol to date was obtained in the presence of BIL-COF-30 as the catalyst under optimized conditions. Besides, BIL-COF-30 can be recycled for at least five runs without activity loss.

Welcome to talk about 100-19-6, If you have any questions, you can contact Du, YR; Xu, BH; Pan, JS; Wu, YW; Peng, XM; Wang, YF; Zhang, SJ or send Email.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. In 2019.0 APPL ORGANOMET CHEM published article about SELECTIVE HYDROGENATION; REDUCTION; LIGANDS; DINUCLEAR; BEARING; DESIGN; WATER in [Pitchaimani, Jayaraman; Madhu, Vedichi] Karunya Inst Technol & Sci Deemed Be Univ, Dept Chem, Coimbatore 641114, Tamil Nadu, India; [Gunasekaran, Nanjappan] SASTRA Deemed Univ, Ctr Nanotechnol & Adv Biomat CenTAB, Thanjavur 613401, Tamil Nadu, India; [Anthony, Savarimuthu Philip] SASTRA Deemed Univ, Sch Chem & Biotechnol, Thanjavur 613401, Tamil Nadu, India; [Moon, Dohyun] Pohang Accelerator Lab, Beamline Dept, 80 Jigokro 127 Beongil, Pohang, Gyeongbuk, South Korea in 2019.0, Cited 36.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A series of air-stable, phosphine-free arene ruthenium (II)-NNN pincer complexes (RuL, RuL1, RuL2 and RuL3) have been synthesized and characterized by spectroscopic and single-crystal X-ray analysis. Further, arene ruthenium (II)-NNN pincer complexes have been used as catalyst for hydrogenation of nitroaromatics into aniline in the presence of NaBH4 at room temperature. The catalytic process suggested highly chemo-selective nitroreduction with wide functional group tolerance.

Formula: C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about SINGLET OXYGEN GENERATION; TRIPLET EXCITED-STATE; VISIBLE-LIGHT ABSORPTION; N-HETEROCYCLIC CARBENE; BODIPY DYES; ELECTROGENERATED CHEMILUMINESCENCE; IRIDIUM(I) COMPLEXES; CARBON-MONOXIDE; PHOTOSENSITIZERS; LIGAND, Saw an article supported by the ARC Centre of Excellence in Exciton ScienceAustralian Research Council [CE170100026]; ANSTO [14297]; Macquarie University through the iMQRES scholarship program; Macquarie University through the receipt of a Macquarie University Research Fellowship (MQRF). Formula: C14H11N. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Wang, DF; Malmberg, R; Pernik, I; Prasad, SKK; Roemer, M; Venkatesan, K; Schmidt, TW; Keaveney, ST; Messerle, BA. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile

While dual photocatalysis-transition metal catalysis strategies are extensively reported, the majority of systems feature two separate catalysts, limiting the potential for synergistic interactions between the catalytic centres. In this work we synthesised a series of tethered dual catalysts allowing us to investigate this underexplored area of dual catalysis. In particular, Ir(i) or Ir(iii) complexes were tethered to a BODIPY photocatalyst through different tethering modes. Extensive characterisation, including transient absorption spectroscopy, cyclic voltammetry and X-ray absorption spectroscopy, suggest that there are synergistic interactions between the catalysts. The tethered dual catalysts were more effective at promoting photocatalytic oxidation and Ir-catalysed dihydroalkoxylation, relative to the un-tethered species, highlighting that increases in both photocatalysis and Ir catalysis can be achieved. The potential of these catalysts was further demonstrated through novel sequential reactivity, and through switchable reactivity that is controlled by external stimuli (heat or light).

Formula: C14H11N. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem