Heterocyclic Building Blocks-benzodioxan

Authors Nguyen, DP; Sladek, RN; Do, LH in PERGAMON-ELSEVIER SCIENCE LTD published article about TRANSFER HYDROGENATION; CARBONYL-COMPOUNDS; LEVULINIC ACID; PRIMARY AMINES; KETONES; ALDEHYDES; ALKYLATION; AMMONIA; HALIDES in [Nguyen, Dat P.; Sladek, Rudolph N.; Do, Loi H.] Univ Houston, Dept Chem, Univ Pk, Houston, TX 77004 USA in 2020.0, Cited 44.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The conversion of aldehydes and ketones to 1 degrees amines could be promoted by half-sandwich iridium complexes using ammonium formate as both the nitrogen and hydride source. To optimize this method for green chemical synthesis, we tested various carbonyl substrates in common polar solvents at physiological temperature (37 degrees C) and ambient pressure. We found that in methanol, excellent selectivity for the amine over alcohol/amide products could be achieved for a broad assortment of carbonyl-containing compounds. In aqueous media, selective reduction of carbonyls to 1 degrees amines was achieved in the absence of acids. Unfortunately, at Ir catalyst concentrations of <1 mM in water, reductive amination efficiency dropped significantly, which suggest that this catalytic methodology might be not suitable for aqueous applications where very low catalyst concentration is required (e.g., inside living cells). (C) 2020 Elsevier Ltd. All rights reserved. Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Nguyen, DP; Sladek, RN; Do, LH or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. In 2019.0 ORG BIOMOL CHEM published article about DOUBLE CARBONYLATION; TERMINAL ALKYNES; C-H; ENANTIOSELECTIVE SYNTHESIS; OXIDATIVE AMIDATION; OXOCARBOXYLIC ACIDS; CHLOROPEPTIN-I; FKBP12 LIGANDS; ARYL IODIDES; DERIVATIVES in [Li, Ping-Gui; Zhu, Hao; Fan, Min; Yan, Cheng; Shi, Kai; Chi, Xi-Wen; Zou, Liang-Hua] Jiangnan Univ, Minist Educ, Sch Pharmaceut Sci, Key Lab Carbohydrate Chem & Biotechnol, Lihu Ave 1800, Wuxi 214122, Jiangsu, Peoples R China; [Li, Ping-Gui] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Xianlin Ave 163, Nanjing 210093, Jiangsu, Peoples R China in 2019.0, Cited 76.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Copper-catalyzed coupling of alpha-keto acids with anthranils is reported for the synthesis of alpha-ketoamides. This process involves N-O/C-O bond cleavages and C-N bond formation. Furthermore, the decarboxylation of alpha-keto acids can be successfully suppressed under redox-neutral conditions.

Welcome to talk about 100-19-6, If you have any questions, you can contact Li, PG; Zhu, H; Fan, M; Yan, C; Shi, K; Chi, XW; Zou, LH or send Email.. Name: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Ruthenium-Catalyzed Annulation of N-Cbz Hydrazones via C-H/N-N Bond Activation for the Rapid Synthesis of Isoquinolines WOS:000471236800006 published article about H ACTIVATION; POLYETHYLENE-GLYCOL; ORGANIC-SYNTHESIS; INTERNAL ALKYNES; DIRECTING GROUP; EFFICIENT SYNTHESIS; IRIDIUM COMPLEXES; O BOND; FUNCTIONALIZATION; RHODIUM in [Deshmukh, Dewal S.; Bhanage, Bhalchandra M.] Inst Chem Technol, Dept Chem, N Parekh Marg, Mumbai 400019, Maharashtra, India in 2019.0, Cited 112.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

In this work, N-Cbz hydrazone has been employed as a rarely explored directing group for the synthesis of isoquinolines by annulation with internal alkynes via C-H/ N-N activation using Ru catalyst. Additive as well as external oxidant-free rapid protocol has been established for the synthesis of isoquinolines using microwave strategy. Use of non-volatile and biodegradable PEG as a green solvent with lower catalyst loading makes the proposed protocol environmentally benign. Further, higher functional group tolerance and wide substrate scope has been observed under the stated methodology with higher yields.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Deshmukh, DS; Bhanage, BM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. Huynh, TV; Doan, KV; Luong, NTK; Nguyen, DTP; Doan, SH; Nguyen, TT; Phan, NTS in [Huynh, Tien, V; Doan, Khang, V; Luong, Ngoc T. K.; Nguyen, Duyen T. P.; Doan, Son H.; Nguyen, Tung T.; Phan, Nam T. S.] Ho Chi Minh City Univ Technol HCMUT, Fac Chem Engn, 268 Ly Thuong Kiet,Dist 10, Ho Chi Minh City, Vietnam; [Huynh, Tien, V; Doan, Khang, V; Luong, Ngoc T. K.; Nguyen, Duyen T. P.; Doan, Son H.; Nguyen, Tung T.; Phan, Nam T. S.] Vietnam Natl Univ Ho Chi Minh City, Linh Trung Ward, Ho Chi Minh City, Vietnam; [Huynh, Tien, V; Luong, Ngoc T. K.; Nguyen, Duyen T. P.] Ho Chi Minh City Univ Food Ind HUFI, Fac Chem Technol, 140 Le Trang Tan, Ho Chi Minh City, Vietnam published New synthesis of 2-aroylbenzothiazoles via metal-free domino transformations of anilines, acetophenones, and elemental sulfur in 2020.0, Cited 43.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A new synthesis of 2-aroylbenzothiazoles via iodine-promoted domino transformations of anilines, acetophenones, and elemental sulfur was demonstrated. The highlights of this tandem synthesis are (1) easily available anilines and acetophenones as feedstock; (2) transition metal-free conditions; (3) inexpensive, nontoxic, easy handling, and abundant elemental sulfur as a building block. This synthetic strategy would complement the existing methods in the synthesis of this important heterocyclic scaffold. To our best knowledge, the formation of 2-aroylbenzothiazoles from simple anilines, acetophenones, and elemental sulfur was not previously reported in the literature.

SDS of cas: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 100-19-6. In 2019.0 ORG LETT published article about 2-AMINOINDOLIZINES; CYCLOADDITION in [Rossler, Matthew D.; Hartgerink, Colin T.; Zerull, Emily E.; Boss, Benjamin L.; Frndak, Abigail K.; Mason, Miles M.; Nickerson, Leslie A.; Romero, Evan O.; Van de Burg, Jaimie E.; Staples, Richard J.; Anderson, Carolyn E.] Calvin Coll, Dept Chem & Biochem, Grand Rapids, MI 49546 USA; [Nickerson, Leslie A.] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA; [Staples, Richard J.] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA in 2019.0, Cited 20.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A new Au(I)-catalyzed method for the preparation of trisubstituted indolizines from easily accessible 2-propargyloxy-pyridines is reported. The reaction tolerates a wide range of functionality, allowing for diversity to be introduced in four distinct regions of the product (R, R-1, R-2, and Ar). The proposed mechanism proceeds via enol addition to an allenamide intermediate and explains the observed increase in yields when electron poor methyl ketones are utilized.

Product Details of 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Chang, D; Chen, JJ; Liu, Y; Huang, HW; Qin, AJ; Deng, GJ in AMER CHEMICAL SOC published article about AGGREGATION-INDUCED EMISSION; PYRROLE-DERIVED ALKALOIDS; INDUCED ENHANCED-EMISSION; SUBSTITUTED PYRROLES; REAL-TIME; CONSTRUCTION; QUINOLINE; COMPOUND; AMINE in [Chang, Dan; Chen, Jinjin; Huang, Huawen; Deng, Guo-Jun] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Minist Educ,Key Lab Environm Friendly Chem & Appl, Xiangtan 411105, Peoples R China; [Liu, Yong; Qin, Anjun; Deng, Guo-Jun] South China Univ Technol, Guangdong Prov Key Lab Luminescence Mol Aggregate, Guangzhou 510640, Peoples R China in 2021, Cited 79. SDS of cas: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal- free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Thiazolidinone/thiazole based hybrids – New class of antitrypanosomal agents WOS:000469159800022 published article about BIOLOGICAL EVALUATION; TRYPANOSOMA-BRUCEI; DRUG DISCOVERY; IN-VITRO; DERIVATIVES; AFRICAN; THIOSEMICARBAZONES; ANTICANCER; INHIBITORS; IDENTIFICATION in [Kryshchyshyn, Anna; Kaminskyy, Danylo; Lesyk, Roman] Danylo Halytsky Lviv Natl Med Univ, Dept Pharmaceut Organ & Bioorgan Chem, Pekarska 69, UA-79010 Lvov, Ukraine; [Karpenko, Oleksandr] Enamine Ltd, Chervonotkatska 78, UA-02094 Kiev, Ukraine; [Gzella, Andrzej] Poznan Univ Med Sci, Dept Organ Chem, Grunwaldzka 6, PL-60780 Poznan, Poland; [Grellier, Philippe] CNRS, UMR 7245, MNHN, Team BAMEE, CP 52,57 Rue Cuvier, F-75005 Paris, France; [Lesyk, Roman] Univ Informat Technol & Management Rzeszow, Dept Publ Hlth Dietet & Lifestyle Disorders, Fac Med, Sucharskiego 2, PL-35225 Rzeszow, Poland in 2019.0, Cited 67.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Different compounds have been investigated as potent drugs for trypanosomiasis treatment, but no new drug has been marketed in the past 3 decades. 4-Thiazolidinone/thiazole as privileged structures and thiosemicarbazides cyclic analogs are well known scaffolds in novel antitrypanosomal agent design. We present here the design and synthesis of new hybrid molecules bearing thiazolidinone/thiazole cores linked by the hydrazone group with various molecular fragments. Structure optimization led to compounds with phenyl-indole or phenyl-imidazo[2,1-b][1,3,4]thiadiazole moieties showing excellent anti-trypanosomal activity towards Trypanosoma brucei brucei and Trypanosoma brucei gambiense. Biological study allowed identifying compounds with the submicromolar levels of IC50, good selectivity indexes and relatively low cytotoxicity upon human primary fibroblasts as well as low acute toxicity. (C) 2019 Elsevier Masson SAS. All rights reserved.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Kryshchyshyn, A; Kaminskyy, D; Karpenko, O; Gzella, A; Grellier, P; Lesyk, R or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about ANTICANCER ACTIVITY; BIOLOGICAL EVALUATION; CHALCONE DERIVATIVES; CYTO-TOXICITY; GROWTH; CANCER; LUNG; AGENTS; PARTHENOLIDE; LACTONE, Saw an article supported by the Gaziosmanpasa University, Scientific Research Projects CommissionGaziosmanpasa University [BAP-2015/91]; TuBTAK (Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [114Z696]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Gurdere, MB; Aydin, A; Yencilek, B; Erturk, F; Ozbek, O; Erkan, S; Budak, Y; Ceylan, M. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Recommanded Product: 100-19-6

Novel enamine derivatives were synthesized from the reaction of lactone and chalcones and their antiproliferative and cytotoxic activities against six cancer cell lines (e. g., HeLa, HT29, A549, MCF7, PC3 and Hep3B) and one normal cell lines (e. g., FL) were investigated along with their mode of interactions with CT-DNA. Most of the enamine derivatives with IC(50)values of 86-168 mu M demonstrated much stronger antiproliferative activity than the starting molecules against the cancer cells. While, among the enamine derivatives, four compounds displayed higher cytotoxic potency than the control drugs (5-fluorouracil and cisplatin) against the Hep3B cell lines, these compounds did not exhibit any significant toxicity against normal cells, FL. The UV/VIS spectral data suggest that eight compounds cause hypochromism with a slight bathochromic shift (similar to 6 nm), indicating that they bind to the DNA by way of an intercalative or minor groove binding mode. The binding constants of the compounds are in the range of 0.1×103 M-1-2.3×104 M-1. The antiproliferative activity of studied enamine derivatives could possibly be due to their DNA binding as well as their cytotoxic properties. In addition to these assays, the chalcones and enamine derivatives were investigated by molecular docking to calculate the synergistic effect of antiproliferative activities against six human cancer cell lines.

Recommanded Product: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Access to pyrrolo[2,1-a]isoindolediones from oxime acetates and ninhydrin via Cu(i)-mediated domino annulations WOS:000519216700006 published article about O-ACYL OXIMES; RHODIUM(III)-CATALYZED SYNTHESIS; CATALYZED CYCLIZATION; KETOXIME CARBOXYLATES; STRATEGY; CHEMISTRY; PYRIDINES; ALKYNES in [Upare, Atul; Chouhan, Neeraj Kumar; Ramaraju, Andhavaram; Bathula, Surendar Reddy] Indian Inst Chem Technol, Dept Organ Synth & Proc Chem, CSIR, Hyderabad 500007, Andhra Pradesh, India; [Upare, Atul; Chouhan, Neeraj Kumar; Bathula, Surendar Reddy] AcSIR Acad Sci & Innovat Res, Ghaziahad 201002, India; [Sridhar, Balasubramanian] Indian Inst Chem Technol, CSIR, Xray Crystallog Div, Hyderabad 500007, India in 2020.0, Cited 35.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

A copper-mediated domino condensation reaction of readily accessible oxime acetates with ninhydrin is reported to afford pyrrolo[2,1-a]isoindolediones via new C-C & C-N bond formations. A wide range of oxime acetates were shown to generally participate in the reaction to produce the condensed products in excellent yields. The necessary control experiments were performed and the mechanism is proposed to involve sequentially the formation of iminium radical via Cu-mediated N-O bond cleavage of oxime acetates, addition of the radical to ninhydrin and rearrangement via ring expansion.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Upare, A; Chouhan, NK; Ramaraju, A; Sridhar, B; Bathula, SR or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Structural and femtosecond third-order nonlinear optical properties of electron donor- acceptor substituted chalcones: An experimental and computational approach WOS:000569382300005 published article about MOLECULAR-STRUCTURE; 1ST-ORDER HYPERPOLARIZABILITY; 1ST HYPERPOLARIZABILITY; FT-RAMAN; PROP-2-EN-1-ONE; DERIVATIVES; CRYSTAL; DFT; LI; ABSORPTION in [Patil, Parutagouda Shankaragouda; Gummagol, Neelamma B.; Ekbote, Anusha; Maidur, Shivaraj R.] KLE Inst Technol, Dept Phys, Hubballi 580030, Karnataka, India; [Ekbote, Anusha] KLSs Gogte Inst Technol, Dept Phys, Belagavi 590010, Karnataka, India; [Wong, Qin Ai; Quah, Ching Kheng] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George Town 11800, Malaysia; [Shkir, Mohd] King Khalid Univ, Fac Sci, Dept Phys, Adv Funct Mat & Optoelect Lab AFMOL, POB 9004, Abha 61413, Saudi Arabia; [Rao, S. Venugopal] Univ Hyderabad, Adv Ctr Res High Energy Mat ACRHEM, Hyderabad 500046, India in 2020.0, Cited 68.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Formula: C8H7NO3

Structural and third-order nonlinear optical (NLO) properties of two D-pi-A-pi-A [(2E)-3-(3-chlorophenyl)-1-(3-nitrophenyl)prop-2-en-1-one (3C3NC) and (2E)-3-(4-fluorophenyl)-1-(4-nitrophe nyl)prop-2-en-1-one (FNC)] and one D-pi-A-pi-D [(2E)-1-(9-anthryl)-3-(4-fluorophenyl) prop-2-en-1-one (FANC)] type chalcone derivatives were investigated experimentally as well as theoretically. All the three chalcones are centrosymmetric (CS) and crystallized in P2(1)/c space group. In crystal packing, all compounds exhibit CeH center dot center dot center dot O hydrogen bonds and pi center dot center dot center dot pi interactions. From UV-Vis-NIR absorption spectra, the cut-off wavelength and optical band gaps of the chalcones were evaluated. The thermal stability and the melting point of the chalcones were determined from the TGA/DTA techniques. The ultrafast third-order NLO properties of the three chalcones in solution (0.01 M) were evaluated by Z-scan technique using femtosecond (fs) pulses from Ti: Sapphire laser (similar to 150 fs, 80 MHz, 800 nm). Third-order nonlinear absorption (NLA) coefficient (beta similar to 10(-9) cmW(-1)), nonlinear refraction (NLR) index (n(2)similar to 10(-14) cm(2)W(-1)), susceptibility (chi((3)) similar to 10(-12) esu) and molecular hyperpolarizability (gamma(h) similar to 10(-31) esu) were unambiguously determined. The chalcones satisfy the condition to observe reverse saturable absorption (RSA) mechanism (sigma(ex) > sigma(g)). Further, the larger values of sigma(ex)/sigma(g) (similar to 2-3) indicate that the chalcones would exhibit remarkable optical limiting property. The estimated optical limiting (OL) threshold values are in the order of mu J/cm(2). Further, all the chalcones have satisfied the one-photon and two-photon figures of merit conditions (W > 1 and T < 1) for the optical switching applications. In addition to experimental findings, the optimized geometry, HOMO-LUMO energy gap, NLO parameters such as electronic dipole moment, polarizability, first and second hyperpolarizabilities of all the three chalcones were determined theoretically (DFT) for different wavelength at B3LYP/6-311 thorn G (d,p) basic set. The experimentally determined second-order susceptibilities (Z-scan technique) are reasonably in agreement with the computational values (TD-DFT). The MEP surface revealed that the 3C3NC, FNC and FANC molecules have some potential sites for electrophilic and nucleophilic attack. The experimental and computational NLO data clearly suggest that the nonlinearity of chalcone molecules greatly depends on the electron donor and acceptor strengths of the substituents. Further, all the chalcones are potential materials for optical limiting and optical switching applications. (C) 2020 Elsevier B.V. All rights reserved. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem