Heterocyclic Building Blocks-benzodioxan

I found the field of Chemistry; Materials Science; Metallurgy & Metallurgical Engineering very interesting. Saw the article Ni-Au alloy nanoparticles as a high performance heterogeneous catalyst for hydrogenation of aromatic nitro compounds published in 2019.0. Safety of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Lang, LM (corresponding author), Nanjing Xiaozhuang Univ, Lab Adv Funct Mat Nanjing, Nanjing 211171, Jiangsu, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Selective hydrogenation of nitro compounds requires highly active and less expensive materials as a heterogeneous catalyst. As a good candidate, the Ni-Au alloy nanoparticles (NPs) have been synthesized by simple in-situ reduction method, which was loaded to the active carbon with 10 wt % loading amount. The Ni-Au/C catalyst shows superior catalytic performance for hydrogenation of nitro compounds with 100% conversion and selectivity without any by-products, which also indicates good recycle performance for several times use. The prepared catalyst not only reduces the usage amount of noble metal, but also keeps the high catalytic activity, which is a promising catalyst for industry applications. (C) 2019 Elsevier B.V. All rights reserved.

Safety of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Lang, LM; Pan, ZR; Yan, J or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Probing the high potency of pyrazolyl pyrimidinetriones and thioxopyrimidinediones as selective and efficient non-nucleotide inhibitors of recombinant human ectonucleotidases WOS:000475378400004 published article about ALKALINE-PHOSPHATASE; BIOLOGICAL EVALUATION; PHOSPHODIESTERASE-I; DERIVATIVES; PROTEIN; IDENTIFICATION; AGENTS; CALCIFICATION; LOCALIZATION; THIAZOLES in [Andleeb, Hina; Hameed, Shahid; Khan, Imtiaz] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan; [Andleeb, Hina] Int Islamic Univ, Fac Basic & Appl Sci, Sulaiman Bin Abdullah Aba Al Khail Ctr Interdisci, Islamabad, Pakistan; [Ejaz, Syeda Abida; Zaib, Sumera; Iqbal, Jamshed] COMSATS Inst Informat Technol, Ctr Adv Drug Res, Abbottabad 22060, Pakistan; [Khan, Imtiaz] Univ Manchester, Sch Chem, Oxford Rd, Manchester M13 9PL, Lancs, England; [Khan, Imtiaz] Univ Manchester, Manchester Inst Biotechnol, 131 Princess St, Manchester M1 7DN, Lancs, England; [Lecka, Joanna; Sevigny, Jean] Univ Laval, Fac Med, Dept Microbiol Infectiol & Immunol, Quebec City, PQ G1V 0A6, Canada; [Lecka, Joanna; Sevigny, Jean] Univ Laval, CHU Quebec, Ctr Rech, Quebec City, PQ G1V 4G2, Canada in 2019.0, Cited 52.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

With the aim to discover novel, efficient and selective inhibitors of human alkaline phosphatase and nucleotide pyrophosphatase enzymes, two new series of pyrazolyl pyrimidinetriones (PPTs) (6a-g) and thioxopyrimidinediones (PTPs) (6h-n) were synthesized in good chemical yields using Knoevenagel condensation reaction between pyrazole carbaldehydes (4a-g) and pharmacologically active N-alkylated pyrimidinetrione (5a) and thioxopyrimidinedione (5b). The inhibition potential of the synthesized hybrid compounds was evaluated against human alkaline phosphatase (h-TNAP and h-IAP) and ectonucleotidase (h-NPP1 and h-NPP3) enzymes. Most of the tested analogs were highly potent with a variable degree of inhibition depending on the functionalized hybrid structure. The detailed structure-activity relationship (SAR) of PPT and PTP derivatives suggested that the compound with unsubstituted phenyl ring from PPT series led to selective and potent inhibition (6a; IC50= 0.33 +/- 0.02 mu M) of h-TNAP, whereas compound 6c selectively inhibited h-IAP isozyme with IC50 value of 0.86 +/- 0.04 mu M. Similarly, compounds 6b and 6h were identified as the lead scaffolds against h-NPP1 and h-NPP3, respectively. The probable binding modes for the most potent inhibitors were elucidated through molecular docking analysis. Structure-activity relationships, mechanism of action, cytotoxic effects and druglikeness properties are also discussed.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Andleeb, H; Hameed, S; Ejaz, SA; Khan, I; Zaib, S; Lecka, J; Sevigny, J; Iqbal, J or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Niu, PF; Liu, X; Shen, ZL; Li, MC in MDPI published article about SELECTIVE AEROBIC OXIDATION; ELECTRON-TRANSFER KINETICS; HIGHLY EFFICIENT; BENZYL ALCOHOL; ELECTROCATALYTIC ACTIVITY; TEMPO; ALDEHYDES; CATALYST; ELECTROOXIDATION; NITRILES in [Niu, Pengfei; Liu, Xin; Shen, Zhenlu; Li, Meichao] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310032, Zhejiang, Peoples R China; [Niu, Pengfei; Liu, Xin; Li, Meichao] Zhejiang Univ Technol, Res Ctr Anal & Measurement, Hangzhou 310032, Zhejiang, Peoples R China in 2019.0, Cited 72.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The ketones was successfully prepared from secondary alcohols using 9-azabicyclo[3.3.1]nonane-N-oxyl (ABNO) as the catalyst and 2,6-lutidine as the base in acetonitrile solution. The electrochemical activity of ABNO for oxidation of 1-phenylethanol was investigated by cyclic voltammetry, in situ Fourier transform infrared spectroscopy (FTIR) and constant current electrolysis experiments. The resulting cyclic voltammetry indicated that ABNO exhibited much higher electrochemical activity when compared with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) under the similar conditions. A reasonable reaction mechanism of the electrocatalytic oxidation of 1-phenylethanol to acetophenone was proposed. In addition, a series of secondary alcohols could be converted to the corresponding ketones at room temperature in 80-95% isolated yields.

Product Details of 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 MOL DIVERS published article about ORGANIC-REACTIONS; REGIOSELECTIVE SYNTHESIS; DOMINO REACTION; AQUEOUS-MEDIA; CONSTRUCTION; CHEMISTRY; CATALYST; DESIGN; ACCESS; INDOLE in [Anary-Abbasinejada, Mohammad; Nezhad-Shshrokhabadi, Frershteh; Mohammadi, Marziyeh] Vali E Asr Univ, Dept Chem, Rafsanjan 77176, Iran in 2020.0, Cited 58.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

Three-component reaction between arylglyoxals, 1,3-dicetones and enaminoketones leads to new polyfunctionalized tetraone derivatives which may be easily converted to polyfunctionalized pyrroles. Reactions were conducted in water or water-ethanol mixture as green solvents, and all products were isolated by simple washing of the resulting solids with diethyl ether.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Borinic Acid Mediated Hydrosilylations: Reductions of Carbonyl Derivatives WOS:000458273900012 published article about HYDROSILATION; KETONES; SILYLATION; ALDEHYDES; NITRILES; IMINES; AMINES in [Chardon, Aurelien; Rouden, Jacques; Blanchet, Jerome] Normandie Univ, ENSICAEN, UNICAEN, CNRS,LCMT, F-14000 Caen, France in 2019.0, Cited 40.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

4-Fluoro-2-chlorophenylborinic acid acts as a precatalyst in the presence of phenylsilane for the facile reduction of ketones, aldehydes and imines. Notably, synergistic mediation of a tertiary amine was found essential to trigger silicon to boron hydride transfer to generate a key amine-diarylhydroborane Lewis complex.

Category: benzodioxans. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 100-19-6. In 2019.0 CHEM COMMUN published article about ARYL BORONIC ACIDS; HYPERVALENT IODONIUM YLIDE; CATALYZED TRIFLUOROMETHYLTHIOLATION; OXIDATIVE TRIFLUOROMETHYLTHIOLATION; FLUORINATED ETHERS; NUCLEOPHILIC TRIFLUOROMETHYLATION; SUBSTITUENT CONSTANTS; CONVENIENT SYNTHESIS; THIOETHERS; MILD in [Cao, Chengyao Kimmy; Chen, Chao] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China; [Zhang, Yue; Lan, Tianlei] Tianjin Univ Sci & Technol, Coll Chem Engn & Mat Sci, Tianjin 300457, Peoples R China; [Liu, Wei] Tianjin Univ Sci & Technol, Coll Sci, Tianjin, Peoples R China in 2019.0, Cited 83.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Synthesis of alpha-trifluoromethylthio(CF3S-)phosphonium ylides is easily accomplished with a constrained trifluoromethylthiooxide via a proton-transfer procedure without extra base. These CF3S-substituted phosphonium ylides could be applied to Wittig reactions to provide functionalised alkenes in one-pot with high yields.

Product Details of 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Shim, JH; Nam, SH; Kim, BS; Ha, DC in [Shim, Jae Ho; Nam, Si Hun; Ha, Deok-Chan] Korea Univ, Res Inst Nat Sci, Dept Chem, 145 Anam Ro, Seoul 02841, South Korea; [Kim, Byeong-Seon] Gyeongsang Natl Univ, Dept Chem Educ, Jinju 52828, South Korea; [Kim, Byeong-Seon] Gyeongsang Natl Univ, Res Inst Nat Sci, Jinju 52828, South Korea published Organocatalytic Asymmetric Michael Addition of Ketones to alpha,beta-Unsaturated Nitro Compounds in 2020, Cited 34. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

An organic catalyst (R,R)-1,2-diphenylethylenediamine(DPEN) derivative” was devel-oped as a chiral bifunctional organocatalyst and applied for asymmetric Michael additions of aromatic ketones totrans-beta-nitroalkene compounds under neutral conditions. The isopropyl-subs-tituted thiourea catalyst in neutral condition provides high chemical yield and enantioselectivities (ee) (up to 96% yield, 98% ee).

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Shim, JH; Nam, SH; Kim, BS; Ha, DC or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020 INORG CHEM published article about BOND-FORMING REACTIONS; TITANIUM COMPLEXES; IMIDO METALLOCENE; CRYSTAL-STRUCTURE; REACTIVITY; CHEMISTRY; ACTIVATION; PHOSPHORUS; RUTHENIUM; PHOSPHIDO in [Wang, Deqiang; Wang, Shichun; Hou, Guohua; Zi, Guofu] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China; [Walter, Marc D.] Tech Univ Carolo Wilhelmina Braunschweig, Inst Anorgan & Analyt Chem, D-38106 Braunschweig, Germany in 2020, Cited 104. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Recommanded Product: 86-29-3

A Lewis base supported terminal uranium phosphinidene, [eta(5)-1,3-(Me3C)(2)C5H3]2U(= P-2,4,6-(Bu3C6H2)-Bu-t)(OPMe3) (5), is isolated from the reaction of the uranium methyl chloride [eta(5)- 1,3-(Me3C)(2)C5H3](2)U(Cl) Me (4) with 2, 4, 6-(Me3C)(3)C6H2PHK in toluene in the presence of Me3PO. Moreover, the reactivity of uranium phospinidene 5 toward a series of small molecules was comprehensively explored. While no reactivity of 5 with internal alkynes is observed attributed to steric hindrance, it readily reacts in good yields with various small molecules including isothiocyanates, aldehydes, imines, diazenes, carbodiimides, nitriles, isonitriles, and organic azides, yielding uranium sulfidos, oxidos, metallaheterocycles, and imido complexes.

Recommanded Product: 86-29-3. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Wang, DQ; Wang, SC; Hou, GH; Zi, GF; Walter, MD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. In 2019.0 SYNTHETIC COMMUN published article about ONE-POT SYNTHESIS; ION-EXCHANGE-RESINS; N-BROMOSUCCINIMIDE; ALPHA,BETA-UNSATURATED KETONES; SECONDARY ALCOHOLS; DIOXANE-DIBROMIDE; SILICA-GEL; ONE-STEP; CONVERSION; REAGENT in [Han, Bingbing; Zheng, Zubiao; Zheng, Dongcheng; Zhang, Lei; Cui, Peng; Shi, Jianjun; Li, Changjiang] Huangshan Univ, Dept Chem, 44 Daizhen Rd, Huangshan 245041, Anhui, Peoples R China in 2019.0, Cited 49.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The applications of a new supported tribromide reagent based on poly(vinylbenzyltrimethylammonium hydroxide) resin (Amberlite 717) were reported. This supported tribromide resin was used directly in alpha-bromination and alpha-bromoacetalization of acetophenones without any other catalyst under mild conditions. The effects of solvents and the amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of alpha-bromo and alpha-bromoacetal of acetophenones were selectively obtained in excellent yields. [GRAPHICS] .

Computed Properties of C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Han, BB; Zheng, ZB; Zheng, DC; Zhang, L; Cui, P; Shi, JJ; Li, CJ or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 1-(4-Nitrophenyl)ethanone. Authors Gao, F; Yang, JH; Geng, Y; Liu, B; Zhang, R; Zhang, M in SPRINGER INTERNATIONAL PUBLISHING AG published article about in [Gao, Feng; Yang, Jihong; Geng, Yan; Liu, Bo; Zhang, Rui; Zhang, Meng] Hebei Univ, Affiliated Hosp, Dept Hepatobiliary Surg, Baoding 071000, Hebei, Peoples R China in 2021.0, Cited 32.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Liver cancer is one of the most important cancers that easily affects many organs in the body. Valproate is a well-known branched fatty acid and is commonly used as an antiepileptic in liver cancer therapy. Similar to many drugs, this chemical drug can induce fulminant liver failure in patients with liver cancer. So, finding new therapeutic agents with fewer side effects is of great attention. This study explains synthesis and characterization of a new effective nanocatalyst ZnO@SiO2-NH2, which can be a suitable candidate for valproate. The prepared nanocatalyst was characterized by FT-IR, TEM, XRD and FE-SEM and formation of the desired nanoparticles with a medium grain size of 70-90 nm is justified. Then, the synthesized nanocatalyst is checked in the multi-component synthesis of some important model drugs involving substituted 2-aminothiophenes, as effective compounds against human liver cancer. The present methodology showed good generality and wide scope, nearly short span of time, good yield, easy workup and environmental friendly conditions for the preparation of the target compounds. At the final part of this study, the in vitro cytotoxicity potential of the prepared nanoparticle is investigated against a well-known human cancer cell line HepG2 via the MTT assay. The experiments reveal that ZnO@SiO2-NH2 nanoparticles have significant cytotoxicity towards the selected cell line. As a result, although ZnO@SiO2-NH2 can be used to treat liver cancer cells, however, this nanoparticle can be utilized to synthesize 2-aminothiophenes, as effective anti-liver cancer drugs like valproate.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem