Heterocyclic Building Blocks-benzodioxan

Authors Hafliger, J; Livingstone, K; Daniliuc, CG; Gilmour, R in ROYAL SOC CHEMISTRY published article about in [Haefliger, Joel; Livingstone, Keith; Daniliuc, Constantin G.; Gilmour, Ryan] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany in 2021.0, Cited 17.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Simple alpha-(bromomethyl)styrenes can be processed to a variety of 1,1-difluorinated electrophilic building blocks via I(I)/I(III) catalysis. This inexpensive main group catalysis strategy employs p-TolI as an effective organocatalyst when combined with Selectfluor (R) and simple amine center dot HF complexes. Modulating Bronsted acidity enables simultaneous geminal and vicinal difluorination to occur, thereby providing a platform to generate multiply fluorinated scaffolds for further downstream derivatization. The method facilitates access to a tetrafluorinated API candidate for the treatment of amyotrophic lateral sclerosis. Preliminary validation of an enantioselective process is disclosed to access alpha-phenyl-beta-difluoro-gamma-bromo/chloro esters.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Hafliger, J; Livingstone, K; Daniliuc, CG; Gilmour, R or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Nikoofar, K; Mehrikaram, F in [Nikoofar, Kobra; Mehrikaram, Fatemeh] Alzahra Univ, Dept Chem, Fac Phys & Chem, Tehran 1993891176, Iran published Graphite decorated nano alumina (nano Al2O3@C-g): A versatile inorganic nano-promoter for the synthesis of 4-alkyl-5-methyl-1H-pyrazol-3-ols in aqueous media in 2019.0, Cited 34.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A benign, simple, and efficient synthesis of 4-alkyl-5-methyl-1H-pyrazol-3-ols has been described in refluxing water through the four-component reaction of beta-ketoesters, hydrazine hydrate, different aldehydes, and acetophenone derivatives in the presence of nano Al2O3@Cg, as a novel nanocatalyst. The new promoter has been prepared via a straightforward procedure and characterized by fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDAX), thermogravimetric analysis (TGA), field emission scanning electron microscopy (FESEM), and inductively coupled plasma atomic emission spectroscopy (ICP-AES) techniques. Utilizing water as the reaction medium, uncomplicated operational procedure, mild reaction conditions, application of a cost-effective, nontoxic, heterogeneous, easily available nanoscale inorganic-based catalyst, wide-range of substrates usage, and recovery and reusability of nano Al2O3@Cg catalyst within 4 runs without activity loss, are some highlighted features of the reported method. (C) 2018 Published by Elsevier Ltd.

Welcome to talk about 100-19-6, If you have any questions, you can contact Nikoofar, K; Mehrikaram, F or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis of Chalcone-Derived Heteroaromatics with Antibacterial Activities WOS:000587726400012 published article about ADDITION/OXIDATIVE CYCLIZATION; OXIDATION; SOLVENT; ESTERS; FURANS in [Jin, Hui; Jiang, Xia; Wang, Tingshu; Koo, Sangho] East China Univ Sci & Technol, Sch Pharm, Meilong Rd 130, Shanghai 200237, Peoples R China; [Jin, Hui; Jiang, Xia; Yoo, Hyebin; Wang, Tingshu; Koo, Sangho] Myongji Univ, Dept Energy Sci & Technol, Myongji Ro 116, Yongin 17058, Gyeonggi Do, South Korea; [Sung, Chul Gi; Choi, Umji; Lee, Chang-Ro] Myongji Univ, Dept Biol Sci & Bioinformat, Myongji Ro 116, Yongin 17058, Gyeonggi Do, South Korea; [Yu, Haiyang] Tianjin Univ Tradit Chinese Med, Tianjin State Key Lab Modern Chinese Med, Tianjin 300193, Peoples R China in 2020.0, Cited 31.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Computed Properties of C8H7NO3

An efficient synthetic method of medicinally important chalcone-derived heteroaromatics was proposed, which comprised of conjugate addition of ethyl acetoacetate to chalcones, followed by Mn-III/Co-II-catalyzed oxidative deacetylation. Paal-Knorr reactions of the resulting 1,4-dicarbonyl compounds containing various phenyl substituents produced the corresponding 2-carboethoxy-3,5-diphenyl furans, pyrroles, and thiophenes. The scope, mechanism, and electronic requirements for the phenyl substituents of chalcones in the key radical-medicated deacetylation reaction were fully elucidated. Antibacterial activities of the 21 chalcone-derived heteroaromatics were screened for Escherichia coli, Staphylococcus aureus, and Acinetobacter baumannii. The parent pyrrole 5 a showed most effective inhibition for E. coli and one third of the heteroaromatics exhibited significant inhibition for S. aureus at the concentration of 64 mu g/mL.

Computed Properties of C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Jin, H; Jiang, X; Yoo, H; Wang, TS; Sung, CG; Choi, U; Lee, CR; Yu, HY; Koo, S or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Xiao, FH; Yuan, SS; Huang, HW; Zhang, F; Deng, GJ in [Xiao, Fuhong; Yuan, Shanshan; Huang, Huawen; Deng, Guo-Jun] Xiangtan Univ, Coll Chem, Key Lab Environm Friendly Chem & Applicat, Minist Educ,Key Lab Green Organ Synth & Applicat, Xiangtan 411105, Peoples R China; [Zhang, Feng] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China published Copper-Catalyzed Three-Component Domino Cyclization for the Synthesis of 4-Aryl-5-(arythio)-2-(trifluoromethyl)oxazoles in 2019.0, Cited 59.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A copper-catalyzed oxidative cyclization of oxime, arylthiol, and trifluoroacetic anhydride for the construction of trisubstituted oxazoles has been developed. This transformation combines N-O bond cleavage, C-H functionalization, and intramolecular annulation, providing a practical protocol for the introduction of a trifluoromethyl (-CF3) group at oxazole rings.

Welcome to talk about 100-19-6, If you have any questions, you can contact Xiao, FH; Yuan, SS; Huang, HW; Zhang, F; Deng, GJ or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C14H11N. In 2020 J AM CHEM SOC published article about PALLADIUM-CATALYZED 1,4-DIFUNCTIONALIZATION; LIGHT PHOTOREDOX CATALYSIS; CROSS-COUPLING REACTIONS; CARBON BOND FORMATION; DOMINO REACTIONS; HECK REACTION; C-C; CONJUGATED DIENES; ATOM-TRANSFER; HALIDES in [Huang, Huan-Ming; Bellotti, Peter; Pflueger, Philipp M.; Schwarz, J. Luca; Glorius, Frank] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany; [Heidrich, Bastian] Westfalische Wilhelms Univ Munster, MEET Battery Res Ctr, Inst Phys Chem, D-48149 Munster, Germany in 2020, Cited 139. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable beta-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 a). Sequential C(sp(3))-C(sp(3)) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.

Computed Properties of C14H11N. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Huang, HM; Bellotti, P; Pfluger, PM; Schwarz, JL; Heidrich, B; Glorius, F or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Ni-Au alloy nanoparticles as a high performance heterogeneous catalyst for hydrogenation of aromatic nitro compounds WOS:000467235800033 published article about CHEMOSELECTIVE HYDROGENATION; SELECTIVE HYDROGENATION; GOLD; METAL; REDUCTION; EFFICIENT; AZO in [Lang, Leiming; Pan, Zhaorui; Yan, Jun] Nanjing Xiaozhuang Univ, Lab Adv Funct Mat Nanjing, Nanjing 211171, Jiangsu, Peoples R China; [Lang, Leiming] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China in 2019.0, Cited 30.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Selective hydrogenation of nitro compounds requires highly active and less expensive materials as a heterogeneous catalyst. As a good candidate, the Ni-Au alloy nanoparticles (NPs) have been synthesized by simple in-situ reduction method, which was loaded to the active carbon with 10 wt % loading amount. The Ni-Au/C catalyst shows superior catalytic performance for hydrogenation of nitro compounds with 100% conversion and selectivity without any by-products, which also indicates good recycle performance for several times use. The prepared catalyst not only reduces the usage amount of noble metal, but also keeps the high catalytic activity, which is a promising catalyst for industry applications. (C) 2019 Elsevier B.V. All rights reserved.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Lang, LM; Pan, ZR; Yan, J or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Secondary amines as coupling partners in direct catalytic asymmetric reductive amination Electronic supplementary information (ESI) available: Procedures and spectra. WOS:000465341000014 published article about ALKYL-ARYL KETONES; IR-F-BINAPHANE; ENANTIOSELECTIVE HYDROGENATION; IDENTIFICATION; SALTS in [Wu, Zitong; Du, Shaozhi; Yang, Wenkun; Yang, Xiongyu; Huang, Haizhou; Chang, Mingxin] Northwest A&F Univ, Coll Chem & Pharm, Shanxi Key Lab Nat Prod & Chem Biol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China; [Gao, Guorui] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Univ Shandong, Coll Chem Chem Engn & Mat Sci, 88 Wenhuadong Rd, Jinan 250014, Shandong, Peoples R China in 2019.0, Cited 56.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

The secondary amine participating asymmetric reductive amination remains an unsolved problem in organic synthesis. Here we show for the first time that secondary amines are capable of effectively serving as N-sources in direct asymmetric reductive amination to afford corresponding tertiary chiral amines with the help of a selected additive set under mild conditions (0-25 degrees C). The applied chiral phosphoramidite ligands are readily prepared from BINOL and easily modified. Compared with common tertiary chiral amine synthetic methods, this procedure is much more concise and scalable, as exemplified by the facile synthesis of rivastigmine and N-methyl-1-phenylethanamine.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Wu, ZT; Du, SZ; Gao, GR; Yang, WK; Yang, XY; Huang, HZ; Chang, MX or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Bronsted Acid-Initiated Formal [1,3]-Rearrangement Dictated by beta-Substituted Ene-Aldimines WOS:000474795200015 published article about AMINO-ACIDS; REARRANGEMENT in [Jongwohan, Chanantida; Suzuki, Toshiyasu; Fujinami, Takeshi; Adachi, Kiyohiro; Momiyama, Norie] Inst Mol Sci, Okazaki, Aichi 4448787, Japan; [Jongwohan, Chanantida; Suzuki, Toshiyasu; Momiyama, Norie] SOKENDAI Grad Univ Adv Studies, Okazaki, Aichi 4448787, Japan; [Honda, Yasushi] HPC Syst Inc, West Japan Off, Shimogyo Ku, 646 Nijohanjikicho, Kyoto 6008412, Japan; [Adachi, Kiyohiro] Univ Tokyo, Sch Engn, Dept Appl Chem, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1118656, Japan in 2019, Cited 18. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. HPLC of Formula: C14H11N

The rearrangement of ene-aldimines is a useful reaction for affording homoallylic amines. Despite their utilities in synthetic chemistry, the rearrangement for accessing homoallylic amines substituted at the 2-position remains elusive. In this study, the Bronsted acid-initiated formal [1,3]-rearrangement of ene-aldimines was developed to synthesize 2,4,4-substituted homoallylic amines that were otherwise inaccessible previously. Our study reveals an intermolecular pathway in which the rearrangement proceeds via a protonation-mediated 2-azaallenium cation.

HPLC of Formula: C14H11N. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Jongwohan, C; Honda, Y; Suzuki, T; Fujinami, T; Adachi, K; Momiyama, N or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

COA of Formula: C14H11N. Recently I am researching about BOND FORMATION; HYDROXYPHTHALIMIDE SYNTHESIS; AMINO-ACIDS; ALDEHYDES; FUNCTIONALIZATION; ESTERIFICATION; DERIVATIVES; EFFICIENT; OLIGOMERIZATION; DIMERIZATION, Saw an article supported by the Russian Science FoundationRussian Science Foundation (RSF) [18-13-00027]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Krylov, IB; Lopat’eva, ER; Budnikov, AS; Nikishin, GI; Terent’ev, AO. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile

Cross-dehydrogenative C-O coupling of N-hydroxyimides with ketones, esters, and carboxylic acids was achieved employing the di-tertbutyl peroxide as a source of free radicals and a dehydrogenating agent. The proposed method is experimentally simple and demonstrates the outstanding efficiency for the challenging CH substrates, such as unactivated esters and carboxylic acids. It was shown that N-hydroxyphthalimide drastically affects the oxidative properties of t-BuOOt-Bu by intercepting the t-BuO center dot radicals with the formation of phthalimide-N-oxyl radicals, a species responsible for both hydrogen atom abstraction from the CH reagent and the selective formation of the C-O coupling product by selective radical cross-recombination. The practical applicability of the developed method was exemplified by the single-stage synthesis of commercial reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-hydroxysuccinimide, whereas in the standard synthetic approach, four stages are necessary.

COA of Formula: C14H11N. Welcome to talk about 86-29-3, If you have any questions, you can contact Krylov, IB; Lopat’eva, ER; Budnikov, AS; Nikishin, GI; Terent’ev, AO or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 86-29-3. In 2020 ORGANOMETALLICS published article about H BOND ACTIVATION; SELECTIVE CATALYTIC-HYDROGENATION; HEXAHYDRIDE COMPLEX; LIGANDS PREPARATION; N-H; DEHYDROGENATION; HYDRIDE; VINYLIDENE; RUTHENIUM; REACTIVITY in [Babon, Juan C.; Esteruelas, Miguel A.; Lopez, Ana M.; Onate, Enrique] Univ Zaragoza CSIC, Dept Quim Inorgan, Inst Sintesis Quim & Catalisis Homogenea ISQCH, Ctr Innovac Quim Avanzada ORFEO CINQA, Zaragoza 50009, Spain in 2020, Cited 116. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

The transformation of alkyl nitriles to symmetrical and asymmetrical secondary aliphatic amines promoted by the hexahydride complex OsH6 ((PPr3)-Pr-i)(2) (1) is described, and the mechanisms of the reactions involved are established. Complex 1 catalyzes the aforementioned transformations of aryl-, pyridyl-, and alkoxy-functionalized alkyl nitriles with linear or branched chains. The formation of the secondary amines involves primary imines, primary amines, and secondary imines as organic intermediates. The reactions take place under mild conditions (toluene, 100 degrees C, and 4 bar of H-2). Stoichiometric reactions of 1 with pivalonitrile and 2-methoxyacetonitrile have allowed us to isolate the trihydride azavinylidene derivatives OsH3{=N=CHR}((PPr3)-Pr-i)(2) (R = Bu-t (3), CH2OMe (4)). Their formation involves the insertion of the N-C triple bond of the substrates into an Os-H bond of the unsaturated tetrahydride OsH4 ((PPr3)-Pr-i)(2) (A), which is generated by reductive elimination of H-2 from the hexahydride precursor. The reaction of these trihydride azavinylidene species with H-2 is the key step for the reduction of the N-C triple bond of the nitriles. In the absence of H-2, the attack of A to the azavinylidene ligand produces the rupture of its C(sp(2))-C(sp(3)) bond. As a consequence of this attack and the presence of primary imines and amines in the reaction media, the binuclear complexes ((PPr3)-Pr-i)(2) H4Os(mu-CN)OsH3{kappa(1)-N-(NH= CHCH2OMe)}((PPr3)-Pr-i)(2) (5) and ((PPr3)-Pr-i)(2)H4Os(mu-CN)OsH3{kappa(1)-N-(NH2CH2CH2OMe)}((PPr3)-Pr-i)(2) (6) have been isolated and characterized by X-ray diffraction analysis, for 2-methoxyacetonitrile. DFT calculations reveal noticeable similarities between the hydrogenations of nitriles to primary imines and those of primary imines to primary amines.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Babon, JC; Esteruelas, MA; Lopez, AM; Onate, E or concate me.. Recommanded Product: 86-29-3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem