Heterocyclic Building Blocks-benzodioxan

COA of Formula: C8H7NO3. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo [1,5-a]pyrimidines as novel larotrectinib analogs published in 2020.0, Reprint Addresses Abouzid, KAM (corresponding author), Ain Shams Univ, Fac Pharm, Pharmaceut Chem Dept, Cairo 11566, Egypt.; Abdel-Aziz, HA (corresponding author), Natl Res Ctr, Dept Appl Organ Chem, Cairo 12622, Egypt.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

A series of 2-phenyl-7-(aryl)pyrazolo [1,5-a]pyrimidine-3-carbonitriles 11a-j and 2-phenyl-7-(aryl)pyrazolo[1,5-a]pyrimidine-3,6-dicarbonitriles 16a-c was synthesized by the reaction of 5-amino-3-phenyl-1H-pyrazole-4-carbonitrile (5) with 3-(dimethylamino)-1-arylprop 2 en 1 ones 6a-j or 2-aryl-3-(dimethylamino)acrylonitriles 12a-c, respectively. In addition, 7-amino-5-oxo-2-phenyl-4,5-dihydropyrazolo [1,5-a]pyrimidine-3-carbonitrile (22) was prepared from the reaction of compound 5 with ethyl cyanoacetate. The anticancer activity of the newly synthesized compounds against Huh-7, HeLa, MCF-7 and MDA-MB231 cell lines showed moderate activity of compound 11 f as anti-proliferative agent against Huh-7 cell line with IC50 = 6.3 mu M when compared with doxorubicin (IC50, = 3.2 mu M). On the other hand, compound 16b revealed potent anti-proliferative activity against HeLa cell line with IC50, = 7.8 mu M when compared with doxorubicin (IC50, = 8.1 mu M). Also compound 11i exhibited a promising anti-proliferative activity against MCF-7 cell line (IC50, = 3.0 mu M) whereas IC50 of doxorubicin = 5.9 mu M, finally compounds 11i and 16b have potent activity as anti-proliferative agents against MDA-MB231 cell line with IC50, = 4.32 and 5.74 mu M, respectively when compared with doxorubicin (IC50 = 6.0 mu M).

COA of Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Attia, MH; Elrazaz, EZ; El-Emam, SZ; Taher, AT; Abdel-Aziz, HA; Abouzid, KAM or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Selective Hydrogenation by Carbocatalyst: The Role of Radicals published in 2019.0. Quality Control of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Nishina, Y (corresponding author), Okayama Univ, Grad Sch Nat Sci & Technol, Kita Ku, 3-1-1 Tsushimanaka, Okayama 7008530, Japan.; Nishina, Y (corresponding author), Okayama Univ, Res Core Interdisciplinary Sci, Kita Ku, 3-1-1 Tsushimanaka, Okayama 7008530, Japan.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

The selective hydrogenation of the nitro moiety is a difficult task in the presence of other reducible functional groups such as alkenes or alkynes. We show that the carbon-based (metal-free) catalyst can be used to selectively reduce substituted nitro groups using H-2 as a reducing agent, providing a great potential to replace noble-metal catalysts and contributing to simple and greener strategies for organic synthesis.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ahmad, MS; He, HX; Nishina, Y or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Metallo-aerogels derived from chitosan with encapsulated metal nanoparticles as robust, efficient and selective nanocatalysts towards reduction of nitroarenes WOS:000571690500005 published article about DOPED CARBON; IN-SITU; HYDROGENATION; CATALYSTS; RECOGNITION; HYDROGELS; DESIGN in [Shen, Yajing; Zheng, Qingshu; Liu, Jianhong; Tu, Tao] Fudan Univ, Shanghai Key Lab Mol Catalysis & Innovat Mat, Dept Chem, 2005 Songhu Rd, Shanghai 200438, Peoples R China; [Tu, Tao] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China; [Tu, Tao] Zhengzhou Univ, Coll Chem & Mol Engn, 100 Kexue Ave, Zhengzhou 450001, Peoples R China in 2021.0, Cited 59.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A series of robust metallo-aerogels are readily fabricated by pyrolysis of xerogels derived from chitosan-metal (M = Fe, Co, Ni) hydrogels. Owing to the strong coordination between metal ions and the functional groups (NH2 and OH) of chitosan, metallo-aerogels consisting of encapsulated metal-nanoparticles (MNPs) by graphite shells were obtained, as supported by various characterizations including high-resolution transmission electron microscope (HR-TEM), X-ray diffraction (XRD), and Raman. The resulting metallo-aerogels could be functioned as highly stable, efficient and selective nanocatalysts towards the hydrogenation of nitroarenes to amines at low catalyst loading (1.2 mol.%-2.4 mol.%). Remarkably, the metallo-aerogels could be reused for more than 30 runs without obvious loss of activity and selectivity. These distinguished performances were attributed to the graphitic shells formed during the pyrolysis, which hampered the possible aggregation of MNPs, prevented metal leaching and increased their stability.

Welcome to talk about 100-19-6, If you have any questions, you can contact Shen, YJ; Zheng, QS; Liu, JH; Tu, T or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. Authors Polishchuk, I; Sklyaruk, J; Lebedev, Y; Rueping, M in WILEY-V C H VERLAG GMBH published article about in [Polishchuk, Iuliia; Sklyaruk, Jan; Rueping, Magnus] RWTH Aachen Univ Landoltweg, Inst Organ Chem, Landoltweg 1, Aachen, Germany; [Lebedev, Yury; Rueping, Magnus] King Abdullah Univ Sci & Technol, KAUST Catalysis Ctr, Thuwal, Saudi Arabia in 2021.0, Cited 31.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Half-sandwich iridium complexes bearing bidentate urea-phosphorus ligands were found to catalyze the direct reductive amination of aromatic and aliphatic ketones under mild conditions at 0.5 mol % loading with high selectivity towards primary amines. One of the complexes was found to be active in both the Leuckart-Wallach (NH4CO2H) type reaction as well as in the hydrogenative (H-2/NH4AcO) reductive amination. The protocol with ammonium formate does not require an inert atmosphere, dry solvents, as well as additives and in contrast to previous reports takes place in hexafluoroisopropanol (HFIP) instead of methanol. Applying NH4CO2D or D-2 resulted in a high degree of deuterium incorporation into the primary amine alpha-position.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Polishchuk, I; Sklyaruk, J; Lebedev, Y; Rueping, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. In 2020.0 CATALYSTS published article about N-PHENYL CARBAMATE; SELENIUM-CATALYZED CARBONYLATION; AROMATIC NITRO-COMPOUNDS; OXIDATIVE CARBONYLATION; SYMMETRICAL 1,3-DIARYLUREAS; NITROBENZENE; PALLADIUM; AMINES; LIGANDS; SYSTEM in [Tran, Anh Vy; Huynh Nguyen, Thuy Tram; Nguyen, Thanh Tung; Lee, Hye Jin; Kim, Yong Jin] Korea Univ Sci & Technol UST, Dept Green Proc & Syst Engn, 89 Yangdaegiro Gil, Ipjang Myeon 31056, Cheonan, South Korea; [Baek, Jayeon; Kim, Yong Jin] Korea Inst Ind Technol, Green Chem & Mat Grp, 89 Yangdaegiro Gil, Cheonan Si 31056, South Korea in 2020.0, Cited 57.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The reaction of FeCl3, SeO2, and Pyridine (Py) in the presence of methanol (MeOH) under CO pressure generates a black precipitate, which has been confirmed as ferric di-selenide, FeSe2 through different structure characterization methods. Furthermore, impregnation of 5 wt% of FeSe2 onto gamma-Al2O3 exhibits better catalytic performance than FeSe2 due to the highly dispersed and smaller particle sizes ca. 200-300 nm. The reductive carbonylation of nitrobenzene (NB) was investigated over FeSe2/gamma-Al2O3 as a heterogeneous catalyst, delivering an excellent yield and high selectivity of methyl-N-phenyl carbamate (MPC). Moreover, a set of reactions was performed with variation in the reaction time, temperature, and pressure to investigate the effects of these factors. In particular, FeSe2/gamma-Al2O3 is highly stable and can be recycled for up to five cycles without significant loss in catalytic performance. A mechanistic study was also conducted on this low-cost catalyst system, especially proposing a crucial role of FeSe2 (mu-CO) active species.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. Authors Rahman, T; Borah, G; Gogoi, PK in INDIAN ACAD SCIENCES published article about in [Rahman, Taskia; Borah, Geetika; Gogoi, Pradip K.] Dibrugarh Univ, Dept Chem, Dibrugarh, Assam, India in 2021.0, Cited 50.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The iron oxide was successfully supported on activated clay/carbon through an experimentally viable protocol for both hydrations of nitrile to amide and reduction of nitro compounds to amines. The as-prepared catalyst has been extensively characterised by XPS, SEM-EDX, TEM, TGA, BET surface area measurements and powdered X-ray diffraction (PXRD). A wide variety of substrates could be converted to the desired products with good to excellent yields by using water as a green solvent for both the reactions. The catalyst was recyclable and reusable up to six consecutive cycles without compromising its catalytic proficiency.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Rahman, T; Borah, G; Gogoi, PK or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Efficient aerobic oxidation of ethylbenzene accelerated by cu species in hydrotalcite WOS:000600589400004 published article about PHASE SELECTIVE OXIDATION; METAL-ORGANIC FRAMEWORK; 1 ATM; N-HYDROXYPHTHALIMIDE; CATALYTIC-OXIDATION; ACETOPHENONE; SYSTEM; ALKYLAROMATICS; COMPLEX; KETONES in [Dai, Xuan; Li, Xingyan; Tang, Shuangling; Peng, Xinhua] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Peoples R China; [Zheng, Xuegen; Jiang, Ou] Sinopec Anqing Petrochem Co, Anqing 246000, Peoples R China in 2021.0, Cited 35.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

The simply prepared CuMgAl hydrotalcite (CuMgAl-LDH) has been developed as an efficient catalyst for the aerobic oxidation of ethylbenzene to acetophenone in the presence of N-Hydroxyphthalimide (NHPI). Various alkyl arenes could be tolerated under the selected reaction conditions. The kinetic study showed that the oxidation of ethylbenzene is a first-order reaction over CuMgAl-LDH. The mechanism study indicated that CuMgAl-LDH could accelerate not only the conversion of ethylbenzene, but also the transformation of the alcohol intermediate to ketone. The positive effect of surface basicity of the catalyst on the reaction has been observed in the aerobic oxidation of the ethylbenzene.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Muthukrishnan, I; Karuppasamy, M; Vachan, BS; Rajput, D; Subbiah, N; Maheswari, CU; Sridharan, V in [Muthukrishnan, Isravel; Karuppasamy, Muthu; Vachan, B. S.; Maheswari, C. Uma; Sridharan, Vellaisamy] SASTRA Deemed Univ, Sch Chem & Biotechnol, Dept Chem, Thanjavur 613401, Tamil Nadu, India; [Rajput, Diksha; Sridharan, Vellaisamy] Cent Univ Jammu, Dept Chem & Chem Sci, Jammu 181143, Jammu & Kashmir, India; [Subbiah, Nagarajan] Natl Inst Technol, Dept Chem, Warangal 506004, Telangana, India published Chemodivergent synthesis of functionalized methanodibenzo[b,f][1,5]diazocin-13-ylmethanones and tetrahydroquinolinesviasolvent-dependent AB(2)and A(2)B(2)multicomponent annulation reactions in 2020.0, Cited 66.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A solvent-dependent chemodivergent approach was established for the synthesis of 6,12-methanodibenzo[b,f][1,5]diazocin-13-ylmethanones and 2,3,4-trisubstituted 1,2,3,4-tetrahydroquinolines involving two distinct multicomponent processes under basic conditions. The AB(2)three-component and A(2)B(2)four-component reactions between 2-aminoarylaldehydes and aryl methyl ketones under basic conditions afforded 6,12-methanodibenzo[b,f][1,5]diazocin-13-ylmethanones (up to 95% yield) and trisubstituted tetrahydroquinolines (up to 84% yield), respectively, based on the nature of the solvent employed. The skeletal diversity and complexity were attained in these high atom- and step-economical processes by creating four new bonds in a single synthetic operation from readily available simple starting materials.

Product Details of 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Muthukrishnan, I; Karuppasamy, M; Vachan, BS; Rajput, D; Subbiah, N; Maheswari, CU; Sridharan, V or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Metal-Free Synthesis and Photophysical Properties of 1,2,4-Triarylpyrroles WOS:000606840200009 published article about AGGREGATION-INDUCED EMISSION; PYRROLE-DERIVED ALKALOIDS; INDUCED ENHANCED-EMISSION; SUBSTITUTED PYRROLES; REAL-TIME; CONSTRUCTION; QUINOLINE; COMPOUND; AMINE in [Chang, Dan; Chen, Jinjin; Huang, Huawen; Deng, Guo-Jun] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Minist Educ,Key Lab Environm Friendly Chem & Appl, Xiangtan 411105, Peoples R China; [Liu, Yong; Qin, Anjun; Deng, Guo-Jun] South China Univ Technol, Guangdong Prov Key Lab Luminescence Mol Aggregate, Guangzhou 510640, Peoples R China in 2021, Cited 79. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal- free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about CROSS-COUPLINGS; ALKYL BROMIDES; ACETYLENE; NICKEL; ARYL; METHODOLOGY; DERIVATIVES; ALDEHYDES; HYDROGEN; IODIDES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21722203, 21831002, 21801116]; Shenzhen Special Funds [JCYJ20170412152435366, JCYJ20170307105638498]; Shenzhen Nobel Prize Scientists Laboratory Project [C17783101]. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Dong, XY; Zhang, YF; Ma, CL; Gu, QS; Wang, FL; Li, ZL; Jiang, SP; Liu, XY. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile. Safety of 2,2-Diphenylacetonitrile

Continued development of the Sonogashira coupling has made it a well established and versatile reaction for the straightforward formation of C-C bonds, forging the carbon skeletons of broadly useful functionalized molecules. However, asymmetric Sonogashira coupling, particularly for C(sp(3))-C(sp) bond formation, has remained largely unexplored. Here we demonstrate a general stereoconvergent Sonogashira C(sp(3))-C(sp) cross-coupling of a broad range of terminal alkynes and racemic alkyl halides (>120 examples) that are enabled by copper-catalysed radical-involved alkynylation using a chiral cinchona alkaloid-based P,N-ligand. Industrially relevant acetylene and propyne are successfully incorporated, laying the foundation for scalable and economic synthetic applications. The potential utility of this method is demonstrated in the facile synthesis of stereoenriched bioactive or functional molecule derivatives, medicinal compounds and natural products that feature a range of chiral C(sp(3))-C(sp/sp(2)/sp(3)) bonds. This work emphasizes the importance of radical species for developing enantioconvergent transformations.

Welcome to talk about 86-29-3, If you have any questions, you can contact Dong, XY; Zhang, YF; Ma, CL; Gu, QS; Wang, FL; Li, ZL; Jiang, SP; Liu, XY or send Email.. Safety of 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem