Heterocyclic Building Blocks-benzodioxan

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Recently I am researching about ARENE-RUTHENIUM COMPLEXES; MOLECULAR-ORBITAL METHODS; HIGHLY-ACTIVE CATALYSTS; RUTHENIUM(II)-ARENE COMPLEXES; ANTITUMOR-ACTIVITY; BIOLOGICAL EVALUATION; DENSITY FUNCTIONALS; HUMAN OVARIAN; BASIS-SETS; IN-VITRO, Saw an article supported by the RFBRRussian Foundation for Basic Research (RFBR) [18-33-00676]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Matveevskaya, VV; Pavlov, DI; Sukhikh, TS; Gushchin, AL; Ivanov, AY; Tennikova, TB; Sharoyko, VV; Baykov, SV; Benassi, E; Potapov, AS. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A series of novel mono- and binuclear arene-ruthenium(H) complexes [(p-cym)Ru(L)Cl] containing 11H-indeno [1,2-b]quinoxalin-11-one derivatives or tryptanthrin-6-oxime were synthesized and characterized by X-ray crystallography, IR, NMR spectroscopy, cyclic voltammetry, and elemental analysis. Theoretical calculations invoking singlet state geometry optimiza-tion, solvation effects, and noncovalent interactions were done using density functional theory (DFT). DFT calculations were also applied to evaluate the electronic properties, and time-dependent DFT was applied to clarify experimental UV-vis results. Cytotoxicity for cancerous and noncancerous human cell lines was evaluated with cell viability MTT assay. Complexes demonstrated a moderate cytotoxic effect toward cancerous human cell line PANC-1. The catalytic activity of the complexes was evaluated in transfer hydrogenation of aryl ketones. All complexes exhibited good catalytic activity and functional group tolerance.

Welcome to talk about 100-19-6, If you have any questions, you can contact Matveevskaya, VV; Pavlov, DI; Sukhikh, TS; Gushchin, AL; Ivanov, AY; Tennikova, TB; Sharoyko, VV; Baykov, SV; Benassi, E; Potapov, AS or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article An Efficient Synthesis of Oxime Compounds Catalyzed by Superfine Kaolin under Microwave Irradiation published in 2019. Quality Control of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Hong, Z (corresponding author), Taizhou Univ, Sch Pharmaceut & Mat Engn, Taizhou 318000, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Oxime compounds were efficiently synthesized with aromatic or aliphatic ketones and hydroxylamine hydrochloride as raw materials in the PEG-400 solution, using cheap and readily available superfine kaolin as catalyst under microwave irradiation condition. The effects of the catalyst, the solvent type, reaction time, reaction temperature on the reaction were investigated. The structures of the products were detected by melting point, nuclear magnetic resonance, infrared spectroscopy and mass spectrometry data. This method has the advantages of short reaction times (5 similar to 15 min), good yields, and simple operation as well as environmental friendliness. In addition, the preliminary experiment shows that superfine kaolin could also catalyze transoximation reaction and preparation of oxime ether compounds under microwave irradiation with the yields of 42%similar to 67% and 59%similar to 72%.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Ould, DMC; Carden, JL; Page, R; Melen, RL in [Ould, Darren M. C.; Carden, Jamie L.; Page, Rowan; Melen, Rebecca L.] Cardiff Univ, Sch Chem, Cardiff Catalysis Inst, Cardiff CF10 3AT, Wales published Synthesis and Reactivity of Fluorinated Triaryl Aluminum Complexes in 2020.0, Cited 28.0. COA of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The addition of the Grignard 3,4,5-(ArMgBr)-Mg-F to aluminum(III) chloride in ether generates the novel triarylalane Al(3,4,5-Ar-F)(3)center dot OEt2. Attempts to synthesize this alane via transmetalation from the parent borane with trimethylaluminum gave a dimeric structure with bridging methyl groups, a product of partial transmetalation. On the other hand, the novel alane Al(2,3,(4)-Ar-F)(3) was synthesized from the parent borane and trimethylaluminum. Interestingly, the solid-state structure of Al(2,3,4-Ar-F)(3) shows an extended chain structure resulting from neighboring Al-F contacts. Al(3,4,5-Ar-F)(3)center dot OEt2 was then found to be an effective catalyst for the hydroboration of carbonyls, imines, and alkynes with pinacolborane.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. COA of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis and biological evaluation of novel SIPI-7623 derivatives as farnesoid X receptor (FXR) antagonists WOS:000459517700003 published article about BENZAMIDE; DISCOVERY; ALPHA; ACIDS in [Nian, Si-Yun; Jiang, Zheng-Li] Taizhou Hosp Zhejiang Prov, Dept Clin Pharm, Xi Men St 150, Linhai 317000, Zhejiang, Peoples R China; [Nian, Si-Yun; Wang, Guo-Ping; Xiao, Ying] China State Inst Pharmaceut Ind, Shanghai Inst Pharmaceut Ind, Shanghai 201203, Peoples R China; [Nian, Si-Yun; Wang, Guo-Ping] Aurisco Pharmaceut Yangzhou Co Ltd, Yangzhou 225100, Jiangsu, Peoples R China; [Huang, Mo-Han; Zhou, Yi-Huan; Tan, Xiang-Duan] Guilin Med Univ, Coll Pharm, Guilin 541004, Peoples R China in 2019.0, Cited 21.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Formula: C8H7NO3

Most of reported steroidal FXR antagonists are restricted due to low potency. We described the design and synthesis of novel nonsteroidal scaffold SIPI-7623 derivatives as FXR antagonists. The most potent compound A-11 (IC50 = 7.8 +/- 1.1 mu M) showed better activity compared to SIPI-7623 (IC50 = 40.8 +/- 1.7 mu M) and guggulsterone (IC50 = 45.9 +/- 1.1 mu M). Docking of A-11 in FXR’s ligand-binding domain was also studied.

Formula: C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors de Souza, JM; Abdiaj, I; Chen, JQ; Hanson, K; de Oliveira, KT; McQuade, DT in AMER CHEMICAL SOC published article about CHLORIDE; ENAMINES; CHEMISTRY; ACID; DERIVATIVES; REACTIVITY; PYRIDINES; NITRILES; ACCESS in [de Souza, Juliana M.; Abdiaj, Irini; McQuade, D. Tyler] Virginia Commonwealth Univ, Dept Chem & Life Sci Engn, Richmond, VA 23284 USA; [de Souza, Juliana M.; de Oliveira, Kleber T.] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil; [Chen, Jiaqi; Hanson, Kenneth] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA in 2020.0, Cited 36.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Recently, we demonstrated that ylidenemalononitriles (YMs) react with amines to form cyclic amidines and that the starting linear YMs are nonemissive in solution and the cyclic amidines are fluorescent. These turn-on systems were of interest to us because of their potential as biosensors and synthons for accessing functionalized pyridines. While our original method was promising, several limitations persisted, including access to more functionalized and polar-solvent-soluble structures as well as increased control over the rate of cyclization. Herein, we report a new approach that allows the electrophilic substitution of YMs. These substituted YMs exhibit faster turn-on rates, color tunability, access to polar-solvent-soluble species, and increased control over cyclization rate. This allowed us to significantly expand the fluorophore’s chemical space.

Welcome to talk about 100-19-6, If you have any questions, you can contact de Souza, JM; Abdiaj, I; Chen, JQ; Hanson, K; de Oliveira, KT; McQuade, DT or send Email.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synergistic palladium/enamine catalysis for asymmetric hydrocarbon functionalization of unactivated alkenes with ketones WOS:000475661500013 published article about ALLYLIC ALKYLATION; TRANSITION-METAL; C-H; ALPHA-ALLYLATION; BOND ACTIVATION; ALDEHYDES; ORGANOCATALYSIS; AMINE; HYDROCARBOFUNCTIONALIZATION; COMPLEXES in [Wei, Chiyu; Ye, Xiaohan; Xing, Qingyu; Shi, Xiaodong] Univ S Florida, Dept Chem, Tampa, FL 33620 USA; [Xie, Yan] Quzhou Univ, Coll Chem & Mat Engn, Quzhou 324000, Peoples R China; [Hu, Yong] Shanghai Jiao Tong Univ, Shanghai Childrens Hosp, Dept Neonatol, Shanghai 200040, Peoples R China in 2019.0, Cited 43.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

Synergistic palladium and enamine catalysis was explored to promote ketone addition to unactivated olefins. A secondary amine-based organocatalyst was identified as the optimal co-catalyst for the directed Pd-catalyzed alkene activation. Furthermore, asymmetric hydrocarbon functionalization of unactivated alkenes was also achieved with good to excellent yield (up to 96% yields) and stereoselectivity (up to 96% ee). This strategy presented an efficient approach to prepare alpha-branched ketone derivatives under mild conditions.

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Wei, CY; Ye, XH; Xing, QY; Hu, Y; Xie, Y; Shi, XD or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Huang, X; Li, ZP; Liu, ZX; Zeng, CC; Hu, LM in ELSEVIER SCI LTD published article about HIGHLY SELECTIVE DETECTION; OXIDATIVE STRESS; BORONATE; H2O2; GLUTATHIONE; CANCER in [Huang, Xin; Li, Zhipeng; Liu, Zixin; Zeng, Chengchu; Hu, Liming] Beijing Univ Technol, Beijing Key Lab Environm & Oncol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China in 2019.0, Cited 44.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Hydrogen peroxide (H2O2) can be produced in mitochondria and plays a significant role in physiological metabolism. Overproduction of H2O2 is a hallmark of many diseases. Therefore, it is very important to develop a highly sensitive method for detecting H2O2 both in vivo and in vitro. Previously reported benzil-based fluorescence probes are superior to those based on boronate ester in terms of reaction selectivity. However, the near infrared (NIR) probe with biocompatibility has been rarely reported for the detection of endogenous hydrogen peroxide and the real-time imaging in biological system. Hemicyanine skeleton has been proven to be effective scaffold for NM fluorescent probes for non-invasive optical imaging in vivo. In this paper, a Cy-H2O2 probe for real-time monitoring hydrogen peroxide in organisms was designed by modifying the NIR hemicyanine framework with benzil moiety. The results showed that Cy-H2O2 exhibits high specificity and sensitivity, and has good water solubility and short response time (within 10 min) for detection of hydrogen peroxide in vitro and in vivo. The reaction mechanism was deduced by detecting product of the fluorescent probe reacting with hydrogen peroxide using HPLC. The probe shows a good linear relationship for the specific response to H2O2 within the concentration range of 0-7 mu M and the detection limit is 65 nM. In addition, the probe Cy-H2O2 has been successfully applied to H2O2 detection in living cells and zebrafish.

Welcome to talk about 100-19-6, If you have any questions, you can contact Huang, X; Li, ZP; Liu, ZX; Zeng, CC; Hu, LM or send Email.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Yamanaka, N; Hara, T; Ichikuni, N; Shimazu, S in [Yamanaka, Nobutaka; Hara, Takayoshi; Ichikuni, Nobuyuki; Shimazu, Shogo] Chiba Univ, Dept Appl Chem & Biotechnol, Grad Sch Engn, Inage Ku, 1-33 Yayoi Cho, Chiba 2638522, Japan published Chemoselective Hydrogenation of 4-Nitrostyrene to 4-Aminostyrene by Highly Efficient TiO2 Supported Ni3Sn2 Alloy Catalyst in 2019.0, Cited 40.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Ni3Sn2 alloy catalysts supported on various metal oxides (TiO2, Al2O3, ZrO2, SnO2, and CeO2) were successfully prepared by simple hydrothermal method and then applied to the hydrogenation of 4-nitrostyrene under H-2 3.0 MPa at 423 K. All the supported catalysts hydrogenated the nitro group more preferentially than the olefin group from the initial reaction stages, showing 100% chemoselectivities towards the desired 4-aminostyrene. This may be attributed to sigma-interaction between the oxygen lone pairs in the nitro group and Sn atoms in Ni3Sn2 alloy. By prolonging the reaction times, the 4-aminostyrene yields increased and finally reached the maximum yields. Among the catalysts, Ni3Sn2/TiO2 alloy catalyst showed the highest catalytic activity with remarkably high chemoselectivity towards 4-aminostyrene. The conversion and chemoselectivity were 100% and 79%, respectively, at a reaction time of only 2.5 h. From the physical and chemical characterization of the supported catalysts, it was clear that the catalytic activity was correlated with H-2 uptake. The application of the best catalyst for the hydrogenation of a wide variety of substituted nitroarenes resulted in the chemoselective formation of the corresponding aminoarenes.

Computed Properties of C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Yamanaka, N; Hara, T; Ichikuni, N; Shimazu, S or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article CAN-mediated Oxidative Coupling-Reaction of Xanthenes with Enaminones WOS:000596864300001 published article about C-H ACTIVATION; CERIUM(IV) AMMONIUM-NITRATE; BOND ARYLATION; METAL-FREE; MECHANISTIC INSIGHT; MOLECULAR-OXYGEN; HIGHLY EFFICIENT; CROSS; TETRAHYDROISOQUINOLINES; SP(3) in [Zhang, Changyuan; Qiu, Yun; Chen, Lulu; Xu, Shuting; Guo, Huosheng; Luo, Jian; Tan, Yao] Yichun Univ, Jiangxi Univ Appl Chem & Chem Biol, Coll Chem & Bioengn, Key Lab, 576 Xuefu Rd, Yichun 336000, Peoples R China; [Zhang, Jiantao] Guangdong Univ Petrochem Technol, Coll Chem, Guandu Rd, Maoming 525000, Peoples R China in 2021.0, Cited 63.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

An efficient CAN-mediated C-C bond formation in the oxidative reactions of xanthenes with enaminones under mild reaction conditions are described. A variety of 9H-xanthene-9-ylidene aldehydes could be synthesized in up to 90% yield via one-pot manner with good functional group compatibility, which achieved the simultaneous construction of carbon-carbon double bond and carbon-oxygen double bond.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Zhang, CY; Qiu, Y; Zhang, JT; Chen, LL; Xu, ST; Guo, HS; Luo, J; Tan, Y or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. Authors Song, T; Zhou, X; Wang, XX; Xiao, JL; Yang, Y in ROYAL SOC CHEMISTRY published article about in [Song, Tao; Zhou, Xin; Wang, Xiaoxue; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, 189 Songling Rd, Qingdao 266101, Peoples R China; [Xiao, Jianliang] Univ Liverpool, Dept Chem, Crown St, Liverpool L69 7ZD, Merseyside, England; [Song, Tao; Zhou, Xin; Wang, Xiaoxue; Yang, Yong] Shandong Energy Inst, Qingdao 266101, Peoples R China in 2021.0, Cited 66.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A new methodology for the synthesis of alpha-diketones was reported via a one-pot cascade process from aldehydes and ketones catalyzed by a bifunctional iron nanocomposite using H2O2 as a green oxidant in water. The one-pot strategy showed excellent catalytic stability, comprehensive suitability of substrates and important practical utility for directly synthesizing biologically active and medicinally valuable N-heterocycles via an intermittent process.

Welcome to talk about 100-19-6, If you have any questions, you can contact Song, T; Zhou, X; Wang, XX; Xiao, JL; Yang, Y or send Email.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem