Product Details of 100-19-6. In 2019.0 J HETEROCYCLIC CHEM published article about BEARING BENZOTHIAZOLE; ANTITUMOR-ACTIVITY; IN-VITRO; DERIVATIVES; THIOPHENE; PYRIDINE; HETEROCYCLES; INHIBITORS; THIAZOLE; MOIETY in [Hassan, Aisha Y.] Al Azhar Univ, Fac Sci Girls, Dept Chem, Cairo, Egypt; [Sarg, Marwa T.; Hussein, Ebtehal M.] Al Azhar Univ, Fac Sci Girls, Dept Pharmaceut Organ Chem, Cairo, Egypt in 2019.0, Cited 45.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.
On the pharmaceutical account of the reported anticancer activity of benzothiazole derivatives, differently substituted benzothiazole derivatives 2a-c to 34a,b, attached at 2-position to different heterocyclic moieties, were synthesized via different chemical reactions. Thirteen of the newly synthesized compounds were selected by the National Cancer Institute, Bethesda, Maryland, USA, and evaluated for their in vitro antitumor activity against 60 human tumor cell lines in a one-dose screening panel among which two compounds 4 and 17 showed high activity and were selected for further evaluation in the five-dose full panel assay, in which compound 4 exerted powerful growth inhibitory activity against all cell lines with GI(50) ranging from 0.683 to 4.66 mu M/L in addition to excellent lethal activity against most of the cell lines.
Product Details of 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Hassan, AY; Sarg, MT; Hussein, EM or send Email.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem