Tag: M.W=150-200

Authors Roy, P; Manna, CK; Naskar, R; Mondal, TK in PERGAMON-ELSEVIER SCIENCE LTD published article about ASYMMETRIC TRANSFER HYDROGENATION; SCHIFF-BASE LIGAND; EFFECTIVE CORE POTENTIALS; DENSITY-FUNCTIONAL THEORY; MOLECULAR CALCULATIONS; EXCITATION-ENERGIES; CARBON-SULFUR; RUTHENIUM(II); ACTIVATION; SULFINATO in [Roy, Puspendu; Manna, Chandan Kumar; Naskar, Rahul; Mondal, Tapan Kumar] Jadavpur Univ, Dept Chem, Kolkata 700032, India; [Roy, Puspendu] Univ Calcutta, Dept Chem, Netaji Nagar Day Coll, Kolkata 700092, India in 2019.0, Cited 49.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A new rhodium(III) triphenylphosphine complex having the general formula [Rh(PPh3)(2)(L)Cl] (1) was synthesized by C-S bond cleavage of an ONS donor azo-thioether ligand (L-CH2Ph). The complex was thoroughly characterized by various spectroscopic techniques. Its single crystal X-ray structure exhibits an octahedral geometry around the rhodium(III) center. A cyclic voltammogram of the complex exhibits ligand based quasi-irreversible oxidative and reductive responses. The electronic structure, redox properties and electronic excitations in the complex were interpreted by DFT and TDDFT calculations. The complex effectively catalyzed the transfer hydrogenation reaction of ketones with high yields in i-PrOH in the presence of a base. (C) 2018 Elsevier Ltd. All rights reserved.

Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Roy, P; Manna, CK; Naskar, R; Mondal, TK or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Electrochemically initiated intermolecular C-N formation/cyclization of ketones with 2-aminopyridines: an efficient method for the synthesis of imidazo[1,2-a]pyridines WOS:000464318800007 published article about ONE-POT SYNTHESIS; H FUNCTIONALIZATION; ORGANIC ELECTROSYNTHESIS; ANTITUMOR EVALUATION; OXIDATIVE AMINATION; ANTIVIRAL ACTIVITY; COUPLING REACTION; METAL; DERIVATIVES; INHIBITORS in [Feng, Mei-Lin; Li, Shu-Qi; He, Hui-Zi; Xi, Long-Yi; Chen, Shan-Yong; Yu, Xiao-Qi] Sichuan Univ, Dept Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Sichuan, Peoples R China in 2019.0, Cited 106.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Electrochemical intermolecular C-N formation/cyclization of ketones with 2-aminopyridines using catalytic hydriodic acid as the redox mediator was developed, providing imidazo[1,2-a]pyridines under more environmentally benign conditions. The reaction proceeds in a simple undivided cell, using low toxic ethanol as the solvent, without external oxidants, and exhibits high atom economy. A variety of ketones including acetophenones, unsatruated and alkyl ketones are amenable to this reaction, affording the corresponding products in moderate to excellent yields. A three-component tandem reaction realizing C-N, C-S/C-Se bond formation can also be achieved under standard conditions.

Welcome to talk about 100-19-6, If you have any questions, you can contact Feng, ML; Li, SQ; He, HZ; Xi, LY; Chen, SY; Yu, XQ or send Email.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C14H11N. In 2020 J AM CHEM SOC published article about PALLADIUM-CATALYZED 1,4-DIFUNCTIONALIZATION; LIGHT PHOTOREDOX CATALYSIS; CROSS-COUPLING REACTIONS; CARBON BOND FORMATION; DOMINO REACTIONS; HECK REACTION; C-C; CONJUGATED DIENES; ATOM-TRANSFER; HALIDES in [Huang, Huan-Ming; Bellotti, Peter; Pflueger, Philipp M.; Schwarz, J. Luca; Glorius, Frank] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany; [Heidrich, Bastian] Westfalische Wilhelms Univ Munster, MEET Battery Res Ctr, Inst Phys Chem, D-48149 Munster, Germany in 2020, Cited 139. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable beta-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 a). Sequential C(sp(3))-C(sp(3)) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.

Computed Properties of C14H11N. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Huang, HM; Bellotti, P; Pfluger, PM; Schwarz, JL; Heidrich, B; Glorius, F or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Xiao, FH; Yuan, SS; Huang, HW; Zhang, F; Deng, GJ in [Xiao, Fuhong; Yuan, Shanshan; Huang, Huawen; Deng, Guo-Jun] Xiangtan Univ, Coll Chem, Key Lab Environm Friendly Chem & Applicat, Minist Educ,Key Lab Green Organ Synth & Applicat, Xiangtan 411105, Peoples R China; [Zhang, Feng] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China published Copper-Catalyzed Three-Component Domino Cyclization for the Synthesis of 4-Aryl-5-(arythio)-2-(trifluoromethyl)oxazoles in 2019.0, Cited 59.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A copper-catalyzed oxidative cyclization of oxime, arylthiol, and trifluoroacetic anhydride for the construction of trisubstituted oxazoles has been developed. This transformation combines N-O bond cleavage, C-H functionalization, and intramolecular annulation, providing a practical protocol for the introduction of a trifluoromethyl (-CF3) group at oxazole rings.

Welcome to talk about 100-19-6, If you have any questions, you can contact Xiao, FH; Yuan, SS; Huang, HW; Zhang, F; Deng, GJ or send Email.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis of Chalcone-Derived Heteroaromatics with Antibacterial Activities WOS:000587726400012 published article about ADDITION/OXIDATIVE CYCLIZATION; OXIDATION; SOLVENT; ESTERS; FURANS in [Jin, Hui; Jiang, Xia; Wang, Tingshu; Koo, Sangho] East China Univ Sci & Technol, Sch Pharm, Meilong Rd 130, Shanghai 200237, Peoples R China; [Jin, Hui; Jiang, Xia; Yoo, Hyebin; Wang, Tingshu; Koo, Sangho] Myongji Univ, Dept Energy Sci & Technol, Myongji Ro 116, Yongin 17058, Gyeonggi Do, South Korea; [Sung, Chul Gi; Choi, Umji; Lee, Chang-Ro] Myongji Univ, Dept Biol Sci & Bioinformat, Myongji Ro 116, Yongin 17058, Gyeonggi Do, South Korea; [Yu, Haiyang] Tianjin Univ Tradit Chinese Med, Tianjin State Key Lab Modern Chinese Med, Tianjin 300193, Peoples R China in 2020.0, Cited 31.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Computed Properties of C8H7NO3

An efficient synthetic method of medicinally important chalcone-derived heteroaromatics was proposed, which comprised of conjugate addition of ethyl acetoacetate to chalcones, followed by Mn-III/Co-II-catalyzed oxidative deacetylation. Paal-Knorr reactions of the resulting 1,4-dicarbonyl compounds containing various phenyl substituents produced the corresponding 2-carboethoxy-3,5-diphenyl furans, pyrroles, and thiophenes. The scope, mechanism, and electronic requirements for the phenyl substituents of chalcones in the key radical-medicated deacetylation reaction were fully elucidated. Antibacterial activities of the 21 chalcone-derived heteroaromatics were screened for Escherichia coli, Staphylococcus aureus, and Acinetobacter baumannii. The parent pyrrole 5 a showed most effective inhibition for E. coli and one third of the heteroaromatics exhibited significant inhibition for S. aureus at the concentration of 64 mu g/mL.

Computed Properties of C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Jin, H; Jiang, X; Yoo, H; Wang, TS; Sung, CG; Choi, U; Lee, CR; Yu, HY; Koo, S or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Nikoofar, K; Mehrikaram, F in [Nikoofar, Kobra; Mehrikaram, Fatemeh] Alzahra Univ, Dept Chem, Fac Phys & Chem, Tehran 1993891176, Iran published Graphite decorated nano alumina (nano Al2O3@C-g): A versatile inorganic nano-promoter for the synthesis of 4-alkyl-5-methyl-1H-pyrazol-3-ols in aqueous media in 2019.0, Cited 34.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A benign, simple, and efficient synthesis of 4-alkyl-5-methyl-1H-pyrazol-3-ols has been described in refluxing water through the four-component reaction of beta-ketoesters, hydrazine hydrate, different aldehydes, and acetophenone derivatives in the presence of nano Al2O3@Cg, as a novel nanocatalyst. The new promoter has been prepared via a straightforward procedure and characterized by fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDAX), thermogravimetric analysis (TGA), field emission scanning electron microscopy (FESEM), and inductively coupled plasma atomic emission spectroscopy (ICP-AES) techniques. Utilizing water as the reaction medium, uncomplicated operational procedure, mild reaction conditions, application of a cost-effective, nontoxic, heterogeneous, easily available nanoscale inorganic-based catalyst, wide-range of substrates usage, and recovery and reusability of nano Al2O3@Cg catalyst within 4 runs without activity loss, are some highlighted features of the reported method. (C) 2018 Published by Elsevier Ltd.

Welcome to talk about 100-19-6, If you have any questions, you can contact Nikoofar, K; Mehrikaram, F or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Hafliger, J; Livingstone, K; Daniliuc, CG; Gilmour, R in ROYAL SOC CHEMISTRY published article about in [Haefliger, Joel; Livingstone, Keith; Daniliuc, Constantin G.; Gilmour, Ryan] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany in 2021.0, Cited 17.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Simple alpha-(bromomethyl)styrenes can be processed to a variety of 1,1-difluorinated electrophilic building blocks via I(I)/I(III) catalysis. This inexpensive main group catalysis strategy employs p-TolI as an effective organocatalyst when combined with Selectfluor (R) and simple amine center dot HF complexes. Modulating Bronsted acidity enables simultaneous geminal and vicinal difluorination to occur, thereby providing a platform to generate multiply fluorinated scaffolds for further downstream derivatization. The method facilitates access to a tetrafluorinated API candidate for the treatment of amyotrophic lateral sclerosis. Preliminary validation of an enantioselective process is disclosed to access alpha-phenyl-beta-difluoro-gamma-bromo/chloro esters.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Hafliger, J; Livingstone, K; Daniliuc, CG; Gilmour, R or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Heshmat, M in [Heshmat, Mojgan] Univ Amsterdam, Vant Hoff Inst Mol Sci, Sci Pk 904, NL-1098 XH Amsterdam, Netherlands; [Heshmat, Mojgan] Rhein Westfal TH Aachen, CAT Catalyt Ctr, ITMC, Worringerweg 2, D-52074 Aachen, Germany published Lewis Acidity of Carbon in Activated Carbonyl Group vs. B(C6F5)(3) for Metal-Free Catalysis of Hydrogenation of Carbonyl Compounds in 2021.0, Cited 60.0. SDS of cas: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

In this work, using DFT calculations, we investigated Lewis acidities of carbon (in activated carbonyl group) in comparison to the B(C6F5)(3) in combination with dioxane as the Lewis base (LB) for metal-free catalysis of heterolytic H-2 splitting and hydrogenation of carbonyl compounds. We found that in case of carbon as the Lewis acid (LA) the reaction is controlled by frontier molecular orbital interactions between the H-2 and LA-LB fragments at shorter distances. The steric effects can be reduced by electrophilic substitutions on the carbonyl carbon. Synergic combination between stronger orbital interactions and reduced steric effects can lower the barrier of the H-2 splitting below 10 kcal/mol. With the B(C6F5)(3), the H-2 splitting is controlled by electrostatic interactions, which cause to form an early transition state. An advantage of employing Lewis acidity of the activated carbonyl carbon for hydrogenation is that the hydride-type attack and hydrogenation of the C=O bond occur in a single step throughout H-2 splitting. Hence, stronger Lewis acidity of the C(C=O) reinforces hydrogenation without prohibition of the hydride delivery.

SDS of cas: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Biochemistry & Molecular Biology; Pharmacology & Pharmacy very interesting. Saw the article Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation published in 2019.0. Product Details of 100-19-6, Reprint Addresses Khanye, SD (corresponding author), Rhodes Univ, Dept Chem, Fac Sci, ZA-6140 Grahamstown, South Africa.; Khanye, SD (corresponding author), Rhodes Univ, Ctr Chem & Biomed Res, ZA-6140 Grahamstown, South Africa.; Khanye, SD (corresponding author), Rhodes Univ, Fac Pharm, ZA-6140 Grahamstown, South Africa.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Herein, we propose novel quinolones incorporating an INH moiety as potential drug templates against TB. The quinolone-based compounds bearing an INH moiety attached via a hydrazide-hydrazone bond were synthesised and evaluated against Mycobacterium tuberculosis H37Rv (MTB). The compounds were also evaluated for cytotoxicity against HeLa cell lines. These compounds showed significant activity (MIC90) against MTB in the range of 0.2-8 mu M without any cytotoxic effects. Compounds 10 (MIC90; 0.9 mu M), 11 (MIC90; 0.2 mu M), 12 (MIC90; 0.8 mu M) and compound 15 (MIC90; 0.8 mu M), the most active compounds in this series, demonstrate activities on par with INH and superior to those reported for the fluoroquinolones. The SAR analysis suggests that the nature of substituents at positions -1 and -3 of the quinolone nucleus influences anti-MTB activity. Aqueous solubility evaluation and in vitro metabolic stability of compound 12 highlights favourable drug-like properties for this compound class.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Yakantham, T; Sreenivasulu, R; Alluraiah, G; Tej, MB; Raju, RR in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about INHIBITORY-ACTIVITY; CALCIUM INFLUX; SAR in [Yakantham, T.; Ramesh Raju, R.] Acharya Nagarjuna Univ, Dept Chem, Nagarjuna Nagar 522510, Andhra Pradesh, India; [Sreenivasulu, R.] Jawaharlal Nehru Technol Univ, Univ Coll Engn Autonomous, Dept Chem, Kakinada 533003, Andhra Pradesh, India; [Alluraiah, G.] SV Arts & Sci Coll, Dept Chem, Giddalur 523357, Andhra Pradesh, India; [Tej, M. B.] Sri Ramachandra Inst Higher Educ & Res, Dept Pharm, Chennai 600116, Tamil Nadu, India in 2019.0, Cited 12.0. Recommanded Product: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A series of novel 1,2,3-triazole linked thiazole-1,2-isoxazole derivatives has been designed, synthesized and characterized by H-1 and C-13 NMR, and mass spectral analysis. The compounds have been tested for their anticancer activity towards MCF-7 (breast cancer), A549 (lung cancer), Colo-205 (colon cancer), and A2780 (ovarian cancer) by using the MTT method using etoposide as the reference. Most of the tested compounds demonstrate good to moderate activity against all cell lines. The compounds 14b, 14e, 14g, and 14h are characterized by inhibitory activity stronger than that of etoposide.

Welcome to talk about 100-19-6, If you have any questions, you can contact Yakantham, T; Sreenivasulu, R; Alluraiah, G; Tej, MB; Raju, RR or send Email.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem