Tag: M.W=150-200

Authors Weber, S; Veiros, LF; Kirchner, K in WILEY-V C H VERLAG GMBH published article about MOLECULAR-ORBITAL METHODS; GAUSSIAN-TYPE BASIS; PRIMARY AMINES; SELECTIVE HYDROGENATION; EQUILIBRIUM GEOMETRIES; INSERTION REACTIONS; HYDROFORMYLATION; HYDROGENOLYSIS; APPROXIMATION; ALDEHYDES in [Weber, Stefan; Kirchner, Karl] Vienna Univ Technol, Inst Appl Synthet Chem, Getreidemarkt 9-163-AC, A-1060 Vienna, Austria; [Veiros, Luis F.] Univ Lisbon, Inst Super Tecn, Ctr Quim Estrutural, Av Rovisco Pais 1, P-1049001 Lisbon, Portugal in 2019, Cited 56. HPLC of Formula: C14H11N. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

An efficient additive-free manganese-catalyzed hydrogenation of nitriles to primary amines with molecular hydrogen is described. The pre-catalyst, a well-defined bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dpre)(CO)(3)(CH3)] (dpre=1,2-bis(di-n-propylphosphino)ethane), undergoes CO migratory insertion into the manganese-alkyl bond to form acyl complexes which upon hydrogenolysis yields the active coordinatively unsaturated Mn(I) hydride catalyst [Mn(dpre)(CO)(2)(H)]. A range of aromatic and aliphatic nitriles were efficiently and selectively converted into primary amines in good to excellent yields. The hydrogenation of nitriles proceeds at 100 degrees C with a catalyst loading of 2 mol % and a hydrogen pressure of 50 bar. Mechanistic insights are provided by means of DFT calculations.

HPLC of Formula: C14H11N. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Novel thiazole-pyrazolone hybrids as potent ACE inhibitors and their cardioprotective effect on isoproterenol-induced myocardial infarction published in 2020.0. Category: benzodioxans, Reprint Addresses Su, GY (corresponding author), Shandong Univ, Jinan Cent Hosp, Cheeloo Coll Med, Dept Cardiol, Jinan 250013, Shandong, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A facile synthesis of a group of novel thiazole-pyrazolone hybrids and their investigation for angiotensin-converting enzyme (ACE) inhibition are reported in this study. These compounds were synthesized using a well-known approach, based on the condensation of ethyl acetoacetate with thiazolylhydrazines, and characterized by various spectroscopic and analytical techniques. The entire set of compounds displayed a moderate-to-excellent inhibitory activity against ACE. In particular, compound4iwas found to be the most potent ACE inhibitor and was further studied for cardioprotective effects against isoproterenol (ISO)-induced myocardial infarction (MI) in rats. Compound4iimproved the cardiac function and prevented cardiac injury induced by ISO in Sprague Dawley rats. The levels of oxidative stress and proinflammatory cytokines were also restored to near normal by4ias compared with the ISO group. In the Western blot analysis, compound4iprevented mitochondrial apoptosis after MI by downregulating the expression of cleaved caspase-3 and Bax, with the upregulation of Bcl-2, as compared with the ISO group.

Category: benzodioxans. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. Recently I am researching about C-H-FUNCTIONALIZATION; DEHYDROGENATIVE COUPLING APPROACH; METAL-FREE; OLEFIN SYNTHESIS; BOND ACTIVATION; METHYL KETONES; OXIDATIVE AMINATION; MICHAEL ADDITION; IODINE; AMINES, Saw an article supported by the Science and Engineering Research Board (SERB), India [SB/FT/CS-073/2014]; MHRD, Govt of India under the TEQIP-III Project. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Rastogi, GK; Deka, B; Deb, ML; Baruah, PK. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

We have developed an efficient metal-free route for the synthesis of 1,4-enedione derivatives under microwave irradiation by reacting easily available arylmethylketones with DMSO or diphenyl sulfoxide in the presence of TBAI and persulfate. The reaction is very clean and completes within very short time. All the reagents and catalysts are cheap and environmentally benign. In addition, the E-isomer of the products can easily be transformed into the Z-isomer by using eosin Y photocatalyst under the irradiation of white CFL.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Rastogi, GK; Deka, B; Deb, ML; Baruah, PK or concate me.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 2,2-Diphenylacetonitrile. In 2020 J ORG CHEM published article about BOND FORMATION; HYDROXYPHTHALIMIDE SYNTHESIS; AMINO-ACIDS; ALDEHYDES; FUNCTIONALIZATION; ESTERIFICATION; DERIVATIVES; EFFICIENT; OLIGOMERIZATION; DIMERIZATION in [Krylov, Igor B.; Lopat’eva, Elena R.; Budnikov, Alexander S.; Nikishin, Gennady I.; Terent’ev, Alexander O.] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia; [Lopat’eva, Elena R.; Budnikov, Alexander S.] Mendeleev Univ Chem Technol Russia, 9 Miusskaya Sq, Moscow 125047, Russia in 2020, Cited 68. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

Cross-dehydrogenative C-O coupling of N-hydroxyimides with ketones, esters, and carboxylic acids was achieved employing the di-tertbutyl peroxide as a source of free radicals and a dehydrogenating agent. The proposed method is experimentally simple and demonstrates the outstanding efficiency for the challenging CH substrates, such as unactivated esters and carboxylic acids. It was shown that N-hydroxyphthalimide drastically affects the oxidative properties of t-BuOOt-Bu by intercepting the t-BuO center dot radicals with the formation of phthalimide-N-oxyl radicals, a species responsible for both hydrogen atom abstraction from the CH reagent and the selective formation of the C-O coupling product by selective radical cross-recombination. The practical applicability of the developed method was exemplified by the single-stage synthesis of commercial reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-hydroxysuccinimide, whereas in the standard synthetic approach, four stages are necessary.

Application In Synthesis of 2,2-Diphenylacetonitrile. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. In 2019.0 J ORGANOMET CHEM published article about BASE COMPLEXES APPLICATION; ONE-POT SYNTHESIS; CRYSTAL X-RAY; ARYL HALIDES; BOND FORMATION; RECYCLABLE CATALYST; REUSABLE CATALYST; 3+2 CYCLOADDITION; COUPLING REACTION; COPPER-COMPLEXES in [Layek, Samaresh; Agrahari, Bhumika; Pathak, Devendra D.] Indian Inst Technol ISM, Dept Appl Chem, Dhanbad 826004, Bihar, India; [Dey, Shuvankar] Gujarat Univ, Sch Sci, Dept Chem, Ahmadabad 380009, Gujarat, India; [Ganguly, Rakesh] Nanyang Technol Univ, Div Chem & Biol Chem, Singapore 639798, Singapore in 2019.0, Cited 103.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Benzoylhydrazine based Schiff base-ligated two new copper(II) complexes, [Cu(L-1)(2)] (1) and [Cu(L-2)(2)] (2) were synthesized by the reaction of Cu(CH3COO)(2)center dot H2O with respective Schiff base ligand 1-[(4-nitrophenyl) ethylidene] benzohydrazide (HL1) or 1-[(4-methoxyphenyl)ethylidene]benzohydrazide (HL2). Both complexes were isolated as greenish solid and fully characterized by elemental analysis, FT-IR, EPR, thermo-gravimetric (TG) analysis and Cyclic Voltammetry. The molecular structures of both complexes have also been determined by single crystal X-ray crystallography, which confirmed the co-ordination of Schiff base ligands through N, O donor atoms and distorted square planar geometry around the Cu(II) ion. Both complexes were found to be good homogeneous catalysts for the synthesis of a wide range of substituted thioethers and 5-substituted 1H-tetrazoles in 92% and 93% yield, respectively, at a low catalyst loading (0.5 mol%). The bond angles and distances, as discerned from the DFT calculations, commusurated with the experimental findings. The energy difference between the HOMO and the LUMO, calculated from DFT studies, was found to be 5.645 eV and 6.459 eV for complex 1 and complex 2, respectively. These results are in harmony with the observed higher catalytic activity of complex 1. (c) 2019 Elsevier B.V. All rights reserved.

SDS of cas: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Layek, S; Agrahari, B; Dey, S; Ganguly, R; Pathak, DD or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 BIOORG CHEM published article about ALZHEIMERS-DISEASE; DONEPEZIL; TACRINE; HYBRIDS; DESIGN; E2020 in [Kuzu, Burak; Tan, Meltem; Menges, Nurettin] Van Yuzuncu Yil Univ, Pharmaceut Chem Sect, TR-65080 Van, Turkey; [Kuzu, Burak; Tan, Meltem; Menges, Nurettin] YYU TEKNOKENT, SAFF Chem Reagent R&D Lab, TR-65080 Van, Turkey; [Taslimi, Parham; Gulcin, Ilhami] Ataturk Univ, Dept Chem, TR-25240 Erzurum, Turkey; [Taspinar, Mehmet] Van Yuzuncu Yil Univ, Dept Med Biol, TR-65080 Van, Turkey in 2019.0, Cited 32.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

Mono- or di-substituted imidazole derivatives were synthesized using a one-pot, two-step strategy. All imidazole derivatives were tested for AChE and BChE inhibition and showed nanomolar activity similar to that of the test compound donepezil and higher than that of tacrine. Structure activity relationship studies, docking studies to on X-ray crystal structure of AChE with PDB code 1B41, and adsorption, distribution, metabolism, and excretion (ADME) predictions were performed. The synthesized core skeleton was bound to important regions of the active site of AChE such as the peripheral anionic site (PAS), oxyanion hole (OH), and anionic subsite (AS). Selectivity of the reported test compounds was calculated and enzyme kinetic studies revealed that they behave as competitive inhibitors, while two of the test compounds showed noncompetitive inhibitory behavior. ADME predictions revealed that the synthesized molecules might pass through the blood brain barrier and intestinal epithelial barrier and circulate freely in the blood stream without binding to human serum albumin. While the toxicity of one compound on the WS1 (skin fibroblast) cell line was 1790 mu M, its toxicity on the SH-SY5Y (neuroblastoma) cell line was 950 mu M.

Quality Control of 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. Authors Song, T; Zhou, X; Wang, XX; Xiao, JL; Yang, Y in ROYAL SOC CHEMISTRY published article about in [Song, Tao; Zhou, Xin; Wang, Xiaoxue; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, 189 Songling Rd, Qingdao 266101, Peoples R China; [Xiao, Jianliang] Univ Liverpool, Dept Chem, Crown St, Liverpool L69 7ZD, Merseyside, England; [Song, Tao; Zhou, Xin; Wang, Xiaoxue; Yang, Yong] Shandong Energy Inst, Qingdao 266101, Peoples R China in 2021.0, Cited 66.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A new methodology for the synthesis of alpha-diketones was reported via a one-pot cascade process from aldehydes and ketones catalyzed by a bifunctional iron nanocomposite using H2O2 as a green oxidant in water. The one-pot strategy showed excellent catalytic stability, comprehensive suitability of substrates and important practical utility for directly synthesizing biologically active and medicinally valuable N-heterocycles via an intermittent process.

Welcome to talk about 100-19-6, If you have any questions, you can contact Song, T; Zhou, X; Wang, XX; Xiao, JL; Yang, Y or send Email.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. In 2020.0 ORG LETT published article about GOLD NANOPARTICLES; PHOTOCATALYTIC HYDROGENATION; COPPER; PHOTOCHEMISTRY; NITROAROMATICS; EFFICIENT; NITROSOBENZENE; DEHALOGENATION; PHOTOREDUCTION; NITROBENZENE in [Kallitsakis, Michael G.; Ioannou, Dimitris I.; Lykakis, Ioannis N.] Aristotle Univ Thessaloniki, Dept Chem, Thessaloniki 54124, Greece; [Terzidis, Michael A.] Int Hellen Univ, Dept Nutr Sci & Dietet, Thessaloniki 57400, Greece; [Kostakis, George E.] Univ Sussex, Sch Life Sci, Dept Chem, Brighton BN1 9QJ, E Sussex, England in 2020.0, Cited 63.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

We report the selective photoinduced reduction of nitroarenes to N-arylhydroxylamines. The present methodology facilitates this transformation in the absence of catalyst or additives and uses only light and methylhydrazine. This noncatalytic photoinduced transformation proceeds with a broad scope, excellent functional-group tolerance, and high yields. The potential of this protocol reflects on the selective and straightforward conversion of two general antibiotics, azomycin and chloramphenicol, to the bioactive hydroxylamine species.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about CROSS-COUPLINGS; ALKYL BROMIDES; ACETYLENE; NICKEL; ARYL; METHODOLOGY; DERIVATIVES; ALDEHYDES; HYDROGEN; IODIDES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21722203, 21831002, 21801116]; Shenzhen Special Funds [JCYJ20170412152435366, JCYJ20170307105638498]; Shenzhen Nobel Prize Scientists Laboratory Project [C17783101]. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Dong, XY; Zhang, YF; Ma, CL; Gu, QS; Wang, FL; Li, ZL; Jiang, SP; Liu, XY. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile. Safety of 2,2-Diphenylacetonitrile

Continued development of the Sonogashira coupling has made it a well established and versatile reaction for the straightforward formation of C-C bonds, forging the carbon skeletons of broadly useful functionalized molecules. However, asymmetric Sonogashira coupling, particularly for C(sp(3))-C(sp) bond formation, has remained largely unexplored. Here we demonstrate a general stereoconvergent Sonogashira C(sp(3))-C(sp) cross-coupling of a broad range of terminal alkynes and racemic alkyl halides (>120 examples) that are enabled by copper-catalysed radical-involved alkynylation using a chiral cinchona alkaloid-based P,N-ligand. Industrially relevant acetylene and propyne are successfully incorporated, laying the foundation for scalable and economic synthetic applications. The potential utility of this method is demonstrated in the facile synthesis of stereoenriched bioactive or functional molecule derivatives, medicinal compounds and natural products that feature a range of chiral C(sp(3))-C(sp/sp(2)/sp(3)) bonds. This work emphasizes the importance of radical species for developing enantioconvergent transformations.

Welcome to talk about 86-29-3, If you have any questions, you can contact Dong, XY; Zhang, YF; Ma, CL; Gu, QS; Wang, FL; Li, ZL; Jiang, SP; Liu, XY or send Email.. Safety of 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Metal-Free Synthesis and Photophysical Properties of 1,2,4-Triarylpyrroles WOS:000606840200009 published article about AGGREGATION-INDUCED EMISSION; PYRROLE-DERIVED ALKALOIDS; INDUCED ENHANCED-EMISSION; SUBSTITUTED PYRROLES; REAL-TIME; CONSTRUCTION; QUINOLINE; COMPOUND; AMINE in [Chang, Dan; Chen, Jinjin; Huang, Huawen; Deng, Guo-Jun] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Minist Educ,Key Lab Environm Friendly Chem & Appl, Xiangtan 411105, Peoples R China; [Liu, Yong; Qin, Anjun; Deng, Guo-Jun] South China Univ Technol, Guangdong Prov Key Lab Luminescence Mol Aggregate, Guangzhou 510640, Peoples R China in 2021, Cited 79. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal- free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem