Tag: M.W=150-200

An article Template-free synthesis of graphene-like carbons as efficient carbocatalysts for selective oxidation of alkanes WOS:000518034000024 published article about OXYGEN REDUCTION; CATALYTIC PERFORMANCE; DEHYDROGENATION; NITROGEN; NANOCARBON; NANOTUBES; NANOPARTICLES; HYDROCARBONS; NANOSHEETS; CHEMISTRY in [Hu, Xiang; Liu, Yuchuan; Huang, Haitao; Huang, Baobing; Xie, Zailai] Fuzhou Univ, Coll Chem, 2 Xueyuan Rd, Fuzhou 350116, Peoples R China; [Chai, Guoliang] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China in 2020.0, Cited 53.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Selective oxidation of aromatic alkanes by C-H activation is one of the key reactions in organic synthesis and the chemical industry. Activation of C-H bonds to obtain high-value added products under mild conditions by using sustainable carbocatalysts is of particular interest. Herein, we report a sustainable, green and template-free strategy towards the fabrication of N-doped and N/S codoped carbon nanosheets by metal-free carbonization of bioprecursors guanine and guanine sulfate. The formation of thin and N/S codoped carbon nanosheets was induced by multiple interactions of the nucleobases. Benefiting from the unique textural structure of the as-synthesized carbons, including ultrathin thickness, optimal porosity, and rich structural defects, and the synergistic coupling effect of multiple dopants, the carbon nanosheets show a high catalytic performance with 85% ethylbenzene conversion and 98% selectivity to acetophenone at 80 degrees C after 4 h reaction, which outperforms other equivalent benchmarks (e.g. 8.5 times higher conversion and 3.2 times higher selectivity than those of oxidized carbon nanotubes). Density functional theory simulations indicate that the oxidation of ethylbenzene is catalyzed by the synergistic effect of p-N/S and g-N/S catalysts via an OH radical mechanism. This N/S codoped strategy provides guidance for the design of carbon-based catalysts for the selective oxidation of other alkanes.

Welcome to talk about 100-19-6, If you have any questions, you can contact Hu, X; Liu, YC; Huang, HT; Huang, BB; Chai, GL; Xie, ZL or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Reusable Palladium Nanoparticles Catalyzed Oxime Ether Directed Mono Ortho-Hydroxylation under Phosphine Free Neutral Condition published in 2019.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone, Reprint Addresses Sekar, G (corresponding author), Indian Inst Technol Madras, Dept Chem, Chennai 600036, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

An efficient, reusable and stable binaphthyl stabilized Pd-nanoparticles (Pd-BNP) catalyzed the direct ortho-C-H hydroxylation of acetophenone oxime ethers under neutral and phosphine ligand-free condition has been developed. A readily available, economic, safe and greener oxidant oxone has been used in this direct ortho-hydroxylation. The scope of the reaction has been studied with various acetophenone oxime ethers including electron rich to electron deficient system and the reaction afforded only mono hydroxylated products in a highly regioselective manner. Several control experiment results confirmed that the oxone is the hydroxyl source. The Pd-BNP catalyst has been reused up to five times. The heterogeneous test confirmed that the reaction is catalyzed by the heterogeneous Pd-BNP catalyst.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Saha, R; Perveen, N; Nihesh, N; Sekar, G or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives as a novel selective inhibitor scaffold of JNK3 WOS:000592063200010 published article about TERMINAL KINASE INHIBITORS; SIGNAL-TRANSDUCTION; TARGET in [Hah, Jung-Mi] Hanyang Univ, Coll Pharm, Ansan 04763, South Korea; [Hah, Jung-Mi] Hanyang Univ, Inst Pharmaceut Sci & Technol, Ansan 04763, South Korea in 2020.0, Cited 21.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives were designed and synthesised as selective inhibitors of JNK3, a target for the treatment of neurodegenerative diseases. Following previous studies, we have designed JNK3 inhibitors to reduce the molecular weight and successfully identified a lead compound that exhibits equipotent activity towards JNK3. Kinase profiling results also showed high selectivity for JNK3 among 38 kinases. Among the derivatives, the IC50 value of 8a, (R)-2-(1-(2-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)amino)pyrimidin-4-yl)-5-(3,4-dichlorophenyl)-1H-pyrazol-3-yl)acetonitrile exhibited 227 nM, showing the highest inhibitory activity against JNK3.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Gao, F; Yang, JH; Geng, Y; Liu, B; Zhang, R; Zhang, M in SPRINGER INTERNATIONAL PUBLISHING AG published article about in [Gao, Feng; Yang, Jihong; Geng, Yan; Liu, Bo; Zhang, Rui; Zhang, Meng] Hebei Univ, Affiliated Hosp, Dept Hepatobiliary Surg, Baoding 071000, Hebei, Peoples R China in 2021.0, Cited 32.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Liver cancer is one of the most important cancers that easily affects many organs in the body. Valproate is a well-known branched fatty acid and is commonly used as an antiepileptic in liver cancer therapy. Similar to many drugs, this chemical drug can induce fulminant liver failure in patients with liver cancer. So, finding new therapeutic agents with fewer side effects is of great attention. This study explains synthesis and characterization of a new effective nanocatalyst ZnO@SiO2-NH2, which can be a suitable candidate for valproate. The prepared nanocatalyst was characterized by FT-IR, TEM, XRD and FE-SEM and formation of the desired nanoparticles with a medium grain size of 70-90 nm is justified. Then, the synthesized nanocatalyst is checked in the multi-component synthesis of some important model drugs involving substituted 2-aminothiophenes, as effective compounds against human liver cancer. The present methodology showed good generality and wide scope, nearly short span of time, good yield, easy workup and environmental friendly conditions for the preparation of the target compounds. At the final part of this study, the in vitro cytotoxicity potential of the prepared nanoparticle is investigated against a well-known human cancer cell line HepG2 via the MTT assay. The experiments reveal that ZnO@SiO2-NH2 nanoparticles have significant cytotoxicity towards the selected cell line. As a result, although ZnO@SiO2-NH2 can be used to treat liver cancer cells, however, this nanoparticle can be utilized to synthesize 2-aminothiophenes, as effective anti-liver cancer drugs like valproate.

Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Gao, F; Yang, JH; Geng, Y; Liu, B; Zhang, R; Zhang, M or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. Recently I am researching about BIOLOGICAL EVALUATION; ANTIMYCOBACTERIAL; INHIBITORS; QSAR, Saw an article supported by the Department of Biotechnology, Indo-Spain, New Delhi [BT/IN/Spain/39/SM/2017-2018]. Published in SPRINGER BIRKHAUSER in NEW YORK ,Authors: Pola, S; Banoth, KK; Sankaranarayanan, M; Ummani, R; Garlapati, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A new series of naphthyl chalcones (3a-3p) and their pyrazoline derivatives (4a-4h) were synthesized using substituted acetophenones, substituted naphthaldehydes, and hydrazine hydrate as starting materials. All the synthesized compounds were characterized by IR, NMR, and mass spectrometric analysis and screened for antimycobacterial activity againstMycobacterium tuberculosis H37Rv (ATCC 27924)and antibacterial activity againstStaphylococcus aureus (MTCC 96), Bacillus subtilis (MTCC 441), Escherichia coli (MTCC 443) and Klebsiella pneumonia (MTCC 109). Compounds3band3pexhibited significant antibacterial activity against all the tested bacterial strains. Amongst the synthesized compounds, compound4bwith 2-hydroxy-5-bromophenyl substitution at 3rd position of pyrazoline showed significant antimycobacterial activity with MIC of 6.25 mu M comparable to that of standard isoniazid. The synthesized compounds were further screened for their cytotoxic activity against the MDA-MB-231 and SKOV3 cell lines. The compounds3a,3l,4b,4c,4e, and4hdid not exhibit any cytotoxicity, and other compounds exhibited IC(50)values higher than 8 and 22 mu M against MDA-MB-231 and SKOV3 cell lines, respectively, compared to 1.20 and 1.30 mu M shown by standard doxorubicin. To find out the putative binding mode of significantly active and weakly active compounds, a molecular docking study was also performed. In that, the most active compound4b, displayed a hydrogen bond interaction with docking score of -10.50 kcal/mol and energy of -44.50 weakly active compound3hdid not show any crucial hydrogen bond interaction with the surrounded amino-acid residues and revealed a docking score of -6.74 and docking energy of -42.50.

Category: benzodioxans. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

COA of Formula: C14H11N. Recently I am researching about ASYMMETRIC ALPHA-ALLYLATION; ANION PHASE-TRANSFER; TSUJI-TROST REACTION; C-O BOND; TRANSITION-METAL; BRONSTED ACID; DUAL CATALYSIS; NONCOVALENT INTERACTIONS; TRANSFER HYDROGENATION; OXIDATIVE ADDITION, Saw an article supported by the National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [GM121383, R35 GM118190]; Ministry of Science and Technology, TaiwanMinistry of Science and Technology, Taiwan [106-2917-I-564-056]; EUEuropean Commission [789399]; NSFNational Science Foundation (NSF) [ACI-1548562]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Tsai, CC; Sandford, C; Wu, T; Chen, BY; Sigman, MS; Toste, FD. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile

The mode of asymmetric induction in an enantioselective intramolecular allylic substitution reaction catalyzed by a combination of palladium and a chiral phosphoric acid was investigated by a combined experimental and statistical modeling approach. Experiments to probe nonlinear effects, the reactivity of deuterium-labeled substrates, and control experiments revealed that nucleophilic attack to the pi-allylpalladium intermediate is the enantio-determining step, in which the chiral phosphate anion is involved in stereoinduction. Using multivariable linear regression analysis, we determined that multiple noncovalent interactions with the chiral environment of the phosphate anion are integral to enantiocontrol in the transition state. The synthetic protocol to form chiral pyrrolidines was further applied to the asymmetric construction of C-O bonds at fully substituted carbon centers in the synthesis of chiral 2,2-disubstituted benzomorpholines.

COA of Formula: C14H11N. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Tsai, CC; Sandford, C; Wu, T; Chen, BY; Sigman, MS; Toste, FD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Chitosan hydrochloride mediated efficient, green catalysis for the synthesis of perimidine derivatives WOS:000486421500001 published article about ACTIVE HETEROGENEOUS CATALYST; HIGHLY EFFICIENT; BIOPOLYMER; ACID; POLYMER; COMPLEX in [Shelke, Premchand B.; Pratap, Amit P.] Inst Chem Technol, Dept Oils Oleochem & Surfactants Technol, Mumbai 400019, Maharashtra, India; [Mali, Suraj N.; Chaudhari, Hemchandra K.] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Mumbai, Maharashtra, India in 2019.0, Cited 40.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

Chitosan hydrochloride as biopolymer-based, renewable, and recyclable heterogeneous catalyst was used for efficient one-pot synthesis of perimidine derivatives. This newly developed greener methodology provides a very simple and greener route for the synthesis of perimidines in short time with excellent yield.

Product Details of 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Shelke, PB; Mali, SN; Chaudhari, HK; Pratap, AP or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Yun, RR; Hong, LR; Ma, WJ; Jia, WG; Liu, SJ; Zheng, BS in WILEY-V C H VERLAG GMBH published article about METAL-ORGANIC FRAMEWORKS; CHEMOSELECTIVE HYDROGENATION; EFFICIENT; NANOPARTICLES; NITROARENES; REDUCTION; DEHYDROGENATION; ALDEHYDES; WATER in [Yun, Ruirui; Hong, Lirui; Ma, Wanjiao; Jia, Weiguo; Liu, Shoujie] Anhui Normal Univ, Key Lab Funct Mol Solids, Minist Educ, Coll Chem & Mat Sci, Wuhu 241000, Peoples R China; [Zheng, Baishu] Hunan Univ Sci & Technol, Key Lab Theoret Organ Chem & Funct Mol, Hunan Prov Key Lab Controllable Preparat & Funct, Minist Educ,Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China in 2019.0, Cited 46.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Herein, we designed and prepared a novel Fe/Fe2O3-based catalyst, in which a remarkable synergistic effect has been revealed between Fe and Fe2O3 encapsulated in N-doping porous carbon. The Fe-based catalysts were fabricated via pyrolysis a mixture of MIL-101(Fe) and melamine. The catalyst exhibits exceptionally high catalytic activity (TOFs up to 8898 h(-1) which is about 100 times higher than the similar kinds of catalysts) and chemoselectivity for nitroarene reduction under mild conditions.

Quality Control of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Yun, RR; Hong, LR; Ma, WJ; Jia, WG; Liu, SJ; Zheng, BS or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 2,2-Diphenylacetonitrile. Recently I am researching about FREE SONOGASHIRA COUPLINGS; C-H ARYLATION; CATALYSIS; COMPLEXES, Saw an article supported by the Takeda PharmaceuticalsTakeda Pharmaceutical Company Ltd; Arno Spatola Endowment Graduate Research Fellowship. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Bihani, M; Ansari, TN; Finck, L; Bora, PP; Jasinski, JB; Pavuluri, B; Leahy, DK; Handa, S. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile

A scalable synthetic method is described for both the preparation of ultrasmall palladium nanoparticles and their subsequent use in catalyzing an alpha-arylation reaction of nitriles in aqueous micelles. This method involves the intermediacy of carbanions or keteniminates, which are presumably stabilized by the micellar environment rather than being quenched with water. These Pd nanoparticles are thoroughly characterized. Mechanistic studies using P-31 NMR spectroscopy revealed the binding of phosphine ligand with the Pd surface and control experiment confirmed the zero-oxidation state of palladium. The scope of the transformation is demonstrated over 35 examples, including one at 50 g scale.

Name: 2,2-Diphenylacetonitrile. Welcome to talk about 86-29-3, If you have any questions, you can contact Bihani, M; Ansari, TN; Finck, L; Bora, PP; Jasinski, JB; Pavuluri, B; Leahy, DK; Handa, S or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Authors Ayyash, AN in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Ayyash, A. N.] Univ Fallujah, Dept Appl Chem, Coll Appl Sci, Anbar 00964, Iraq in 2020, Cited 24. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The title compounds, 3,3′,3.,3”’-[methylenebis(oxybenzene-5,1,3-triyl)]tetrakis(6,8-diaryl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepines), were synthesized starting from dimethyl 4-hydroxyisophthalate which was reacted with dibromomethane to obtain tetramethyl 5,5′-[methylenebis(oxy)]di(benzene-1,3-dicarboxylate). The latter was treated with excess hydrazine hydrate, and the resulting tetrahydrazide was converted to tetrakis1,2,4-triazolyl derivative via cyclization with ethanolic potassium hydroxide, carbon disulfide, and hydrazine hydrate. In the final stage, cyclocondensation with substituted chalcones afforded the target products. The structure of the newly synthesized compounds was confirmed by elemental analyses and FT-IR and NMR spectra, and their antimicrobial activities against some bacterial and fungal strains were estimated by the disc diffusion method.

Welcome to talk about 100-19-6, If you have any questions, you can contact Ayyash, AN or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem