Tag: M.W=150-200

An article Formal [2+2+2] Cycloaddition Reaction of a Metal-Carbyne Complex with Nitriles: Synthesis of a Metallapyrazine Complex WOS:000468120200046 published article about INDEPENDENT CHEMICAL-SHIFTS; VINYLIDENE COMPLEXES; OSMIUM CARBYNE; AROMATICITY; CHEMISTRY; STABILIZATION; CONSTRUCTION; ALKYNES; CYCLOTRIMERIZATION; METALLABENZENES in [Lin, Jianfeng; Ding, Linting; Zhuo, Qingde; Zhang, Hong; Xia, Haiping] Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China; [Lin, Jianfeng; Ding, Linting; Zhuo, Qingde; Zhang, Hong; Xia, Haiping] Xiamen Univ, Coll Chem & Chem Engn, Collaborat Innovat Ctr Chem Energy Mat iChEM, Xiamen 361005, Peoples R China; [Xia, Haiping] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Dept Chem, Shenzhen 518055, Peoples R China in 2019, Cited 100. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Formula: C14H11N

Although alkynes have been extensively exploited in [2 + 2 + 2] cycloadditions with nitriles to form N-heterocyclic aromatics, the alkyne-like metal carbon triple bond has never been used in [2 + 2 + 2] cycloadditions with nitriles. We demonstrate the synthesis of the first metallapyrazine through [2 + 2 + 2] cycloaddition reactions of a metal carbyne complex with nitriles. Experimental observations and density functional theory calculations are evidence for the aromatic character of the metallapentalenopyrazine.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Lin, JF; Ding, LT; Zhuo, QD; Zhang, H; Xia, HP or concate me.. Formula: C14H11N

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article A facile microwave-assisted Knoevenagel condensation of various aldehydes and ketones using amine-functionalized metal organic frameworks WOS:000564600100007 published article about IONIC LIQUID; EFFICIENT; CATALYST in [Taher, Abu] European Univ Bangladesh, Dept Ind & Prod Engn, Dhaka 1216, Bangladesh; [Lumbiny, Bilkis Jahan] Univ Rajshahi, Dept Chem, Rajshahi 6205, Bangladesh; [Taher, Abu; Lee, Ik-Mo] Inha Univ, Dept Chem, Incheon 402751, South Korea in 2020.0, Cited 23.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

An amine-functionalized metal organic framework (MOF) was used as highly efficient and recyclable heterogeneous catalyst for Knoevenagel condensation of various aromatic aldehydes and ketones in ethanol. The catalytic efficiency was demonstrated by the high conversion of the reactants with 100% selectivity under microwave (mu W) irradiation, while dramatically reduced the reaction time as compared to the conventional heating method. Importantly, the MOF maintained its structural integrity after catalytic reactions and it could be reused several times without remarkable loss of activity.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Taher, A; Lumbiny, BJ; Lee, IM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Efficient and Practical Transfer Hydrogenation of Ketones Catalyzed by a Simple Bidentate Mn-NHC Complex WOS:000474698500001 published article about ASYMMETRIC TRANSFER HYDROGENATION; HETEROCYCLIC CARBENE COMPLEXES; MANGANESE; LIGANDS; RUTHENIUM; MECHANISM; ACETOPHENONE; REDUCTION; IRIDIUM; RHODIUM in [van Putten, Robbert; Benschop, Joeri; de Munck, Vincent J.; Filonenko, Georgy A.; Pidko, Evgeny A.] Delft Univ Technol, Fac Sci Appl, Inorgan Syst Engn Grp, Dept Chem Engn, Maasweg 9, NL-2629 HZ Delft, Netherlands; [Weber, Manuela; Mueller, Christian] Free Univ Berlin, Inst Chem & Biochem, Fabeckstr 34-36, D-14195 Berlin, Germany in 2019.0, Cited 42.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Catalytic reductions of carbonyl-containing compounds are highly important for the safe, sustainable, and economical production of alcohols. Herein, we report on the efficient transfer hydrogenation of ketones catalyzed by a highly potent Mn(I)-NHC complex. Mn-NHC 1 is practical at metal concentrations as low as 75 ppm, thus approaching loadings more conventionally reserved for noble metal based systems. With these low Mn concentrations, catalyst deactivation is found to be highly temperature dependent and becomes especially prominent at increased reaction temperature. Ultimately, understanding of deactivation pathways could help close the activity/stability-gap with Ru and Ir catalysts towards the practical implementation of sustainable earth-abundant Mn-complexes.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact van Putten, R; Benschop, J; de Munck, VJ; Weber, M; Muller, C; Filonenko, GA; Pidko, EA or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Rastogi, GK; Deka, B; Deb, ML; Baruah, PK in [Rastogi, Gaurav K.; Deka, Bhaskar; Deb, Mohit L.; Baruah, Pranjal K.] Gauhati Univ, GUIST, Dept Appl Sci, Gauhati 781014, Assam, India; [Rastogi, Gaurav K.] NEIST, CSIR, Dept Appl Organ Chem, Jorhat 785006, Assam, India published Diastereoselective sp3-C-H Functionalization of Arylmethyl Ketones and Transformation of E- to Z-Products Through Photocatalysis in 2020.0, Cited 91.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

We have developed an efficient metal-free route for the synthesis of 1,4-enedione derivatives under microwave irradiation by reacting easily available arylmethylketones with DMSO or diphenyl sulfoxide in the presence of TBAI and persulfate. The reaction is very clean and completes within very short time. All the reagents and catalysts are cheap and environmentally benign. In addition, the E-isomer of the products can easily be transformed into the Z-isomer by using eosin Y photocatalyst under the irradiation of white CFL.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Rastogi, GK; Deka, B; Deb, ML; Baruah, PK or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Arif, R; Rana, M; Yasmeen, S; Amaduddin; Khan, MS; Abid, M; Khan, MS; Rahisuddin in [Arif, Rizwan; Rana, Manish; Yasmeen, Shama; Rahisuddin] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India; [Amaduddin; Abid, Mohammad] Jamia Millia Islamia, Dept Biosci, New Delhi 110025, India; [Khan, M. S.] Jamia Millia Islamia, Dept Phys, New Delhi 110025, India; [Khan, Md Shahzad] Galgotias Univ, Sch Basic & Appl Sci, Greater Noida 203201, India published Facile synthesis of chalcone derivatives as antibacterial agents: Synthesis, DNA binding, molecular docking, DFT and antioxidant studies in 2020.0, Cited 63.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A series of beta-chalcones derivatives (1a-11) was synthesized using different substituted amines in basic condition by Claisen-Schmidt condensation reaction. Structural analysis of the synthesized compounds was carried out by various characterization techniques. Antimicrobial properties of the chalcone derivatives (1a-11) were evaluated against different bacterial strains Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica, Staphylococcus pneumoniae and Enterococcus faecalis by disc diffusion method. The pharmacological treatment of chalcones showed that chalcone 1b has promising potential against tested bacterial strains. Ct-DNA was used to study the binding interactions of the potent chalcone derivative 1b by means of absorption spectroscopy, viscosity measurement, fluorescence quenching, cyclic voltammetery and circular dichroism study. Chalcone 1b showed significant binding towards Ct-DNA with intrinsic binding constant (K-b) 1.75 x 10(4)M(-1). Molecular docking study of the target compound was also carried out against B-DNA dodecamer d(CGCGAATTCGCG)(2) and it has been found that chalcone 1b can bind to Ct-DNA via an intercalative mode. For the chalcone derivative 1b and Ct-DNA interaction, static quenching mechanism observed which was further confirmed using time-resolved fluorescence spectroscopy. To optimize the chalcone derivative 1b for HOMO-LUMO energy calculation, Density Functional Theory (DFT) has been used. Time dependent-DFT study has been optimized to generate vertical excitation energies, absorption wavelengths and oscillator strengths of the chalcone derivative lb. Antioxidant activity was also carried out to evaluate the antioxidant nature of the chalcone derivative lb by DPPH and H2O2 assay. (C) 2020 Elsevier B.V. All rights reserved.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Arif, R; Rana, M; Yasmeen, S; Amaduddin; Khan, MS; Abid, M; Khan, MS; Rahisuddin or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about 2 CHK2 INHIBITORS; POTENTIAL ANTICANCER; CARBAZOLES SYNTHESIS; DERIVATIVES; DISCOVERY; SCAFFOLD; BENDAMUSTINE; MOIETY; DRUGS, Saw an article supported by the Indian Council of Medical Research, New Delhi, IndiaIndian Council of Medical Research (ICMR) [58/16/2013BMS]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Sivaramakarthikeyan, R; Shunmugam, I; Vadivel, S; Lim, WM; Mai, CW; Ramalingan, C. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Recommanded Product: 100-19-6

Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a-6j has been obtained from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a hybridpossessing para-nitrophenyl moiety connected to a pyrazole scaffold (6a) exerted the highest anti-inflammatory activity, which is superior to the standard, diclofenac sodium. While executing the 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, a hybrid-possessing para-bromophenyl unit integrated at the pyrazole structural motif (6i) exhibited the highest activity among the hybrids examined. Besides, evaluation of anticancer potency of the synthesized hybrids revealed that the one containing a para-fluorophenyl unit tethered at the pyrazole nucleus (6h) showed the highest activity against both the pancreatic cancer cells (SW1990 and AsPCl) investigated. Considerable binding affinity between B-cell lymphoma and the hybrid, 6h has been reflected while performing molecular docking studies (-8.65 kcal/mol). The outcomes of the investigation expose that these hybrids could be used as effective intermediates to construct more potent biological agents.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sivaramakarthikeyan, R; Shunmugam, I; Vadivel, S; Lim, WM; Mai, CW; Ramalingan, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 2,2-Diphenylacetonitrile. In 2021 CHEM-EUR J published article about CHEMISTRY; COMPLEXES in [Wang, Deqiang; Ding, Wanjian; Hou, Guohua; Zi, Guofu] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China; [Walter, Marc D.] Tech Univ Carolo Wilhelmina Braunschweig, Inst Anorgan & Analyt Chem, Hagenring 30, D-38106 Braunschweig, Germany in 2021, Cited 121. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

The synthesis, electronic structure, and reactivity of a uranium metallacyclopropene were comprehensively studied. Addition of diphenylacetylene (PhC equivalent to CPh) to the uranium phosphinidene metallocene [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U=P-2,4,6-tBu(3)C(6)H(2) (1) yields the stable uranium metallacyclopropene, [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U[eta(2)-C2Ph2] (2). Based on density functional theory (DFT) results the 5f orbital contributions to the bonding within the metallacyclopropene U-(eta(2)-C=C) moiety increases significantly compared to the related Th-IV compound [eta(5)-1,2,4-(Me3C)(3)C5H2](2)Th[eta(2)-C2Ph2], which also results in more covalent bonds between the [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U2+ and [eta(2)-C2Ph2](2-) fragments. Although the thorium and uranium complexes are structurally closely related, different reaction patterns are therefore observed. For example, 2 reacts as a masked synthon for the low-valent uranium(II) metallocene [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U-II when reacted with Ph2E2 (E=S, Se), alkynes and a variety of hetero-unsaturated molecules such as imines, ketazine, bipy, nitriles, organic azides, and azo derivatives. In contrast, five-membered metallaheterocycles are accessible when 2 is treated with isothiocyanate, aldehydes, and ketones.

Recommanded Product: 2,2-Diphenylacetonitrile. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Wang, DQ; Ding, WJ; Hou, GH; Zi, GF; Walter, MD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2021.0 J ORG CHEM published article about DIMETHYL-SULFOXIDE; AMINOOXYGENATION; 2-AMINOPYRIDINES; DERIVATIVES; IMIDAZO; KETONES; ALKYNES; ACCESS in [Zhang, Yi; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Inst Adv Studies, Taizhou 318000, Peoples R China; [Zhang, Yi; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China; [Zhang, Yi; Ma, Yongmin] Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China in 2021.0, Cited 43.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

A convenient one-pot, three-component reaction has been developed for the synthesis of 3-aroylimidazo[1,2-a]-N-hetero-cycles from aryl ketones and 2-amino-N-heterocycles using dimethyl sulfoxide as a methylene donor. The reaction proceeds smoothly catalyzed by I-2 in the presence of K2S2O8 and affords the desired products in moderate to good yields. This protocol offers significant superiority in accessing biologically active 3-aroylimidazo[1,2-a]-N-heterocycles with various substitution patterns.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, Y; Chen, RE; Wang, ZM; Wang, L; Ma, YM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Lesanavicius, M; Aliverti, A; Sarlauskas, J; Cenas, N in MDPI published article about ELECTRON-TRANSFER REACTIONS; CYTOCHROME P450 REDUCTASE; FERREDOXIN-NADP(+) REDUCTASE; SINGLE-ELECTRON; 1,4-DI-N-OXIDE DERIVATIVES; NADPH; QUINONES; FAD; TIRAPAZAMINE; POTENTIALS in [Lesanavicius, Mindaugas; Sarlauskas, Jonas; Cenas, Narimantas] Vilnius Univ, Inst Biochem, Dept Xenobiot Biochem, Sauletekio 7, LT-10257 Vilnius, Lithuania; [Aliverti, Alessandro] Univ Milan, Dept Biosci, Via Celoria 26, I-20133 Milan, Italy in 2020, Cited 49. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Ferredoxin:NADP(+) oxidoreductase from Plasmodium falciparum (PfFNR) catalyzes the NADPH-dependent reduction of ferredoxin (PfFd), which provides redox equivalents for the biosynthesis of isoprenoids and fatty acids in the apicoplast. Like other flavin-dependent electrontransferases, PfFNR is a potential source of free radicals of quinones and other redox cycling compounds. We report here a kinetic study of the reduction of quinones, nitroaromatic compounds and aromatic N-oxides by PfFNR. We show that all these groups of compounds are reduced in a single-electron pathway, their reactivity increasing with the increase in their single-electron reduction midpoint potential (E-7(1)). The reactivity of nitroaromatics is lower than that of quinones and aromatic N-oxides, which is in line with the differences in their electron self-exchange rate constants. Quinone reduction proceeds via a ping-pong mechanism. During the reoxidation of reduced FAD by quinones, the oxidation of FADH(.) to FAD is the possible rate-limiting step. The calculated electron transfer distances in the reaction of PfFNR with various electron acceptors are similar to those of Anabaena FNR, thus demonstrating their similar intrinsic reactivity. Ferredoxin stimulated quinone- and nitro-reductase reactions of PfFNR, evidently providing an additional reduction pathway via reduced PfFd. Based on the available data, PfFNR and possibly PfFd may play a central role in the reductive activation of quinones, nitroaromatics and aromatic N-oxides in P. falciparum, contributing to their antiplasmodial action.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Lesanavicius, M; Aliverti, A; Sarlauskas, J; Cenas, N or concate me.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Copper-Catalyzed [2+2+1+1] Annulation for the Regioselective Synthesis of 2,6-Diarylpyridines via C1-Insertion and Subsequent Cyclization published in 2020.0, Reprint Addresses Malakar, CC (corresponding author), Natl Inst Technol Manipur, Dept Chem, Imphal 795004, Manipur, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

Copper-catalyzed [2+2+1+1] annulation strategy has been investigated for the regioselective synthesis of symmetrical and unsymmetrical 2,6-diarylpyridines using aliphatic amines as nitrogen source and DMSO as C1-synthon. The developed protocol was successful for the transformation of non-activated aromatic ketones and non-activated aliphatic amines into 2,6-diarylpyridinesviaan easy to access approach. This protocol has been verified on wide range of substrates having various functional groups.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Vodnala, N; Gujjarappa, R; Satheesh, V; Gupta, R; Kaldhi, D; Kabi, AK; Malakar, CC or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem