Tag: M.W=150-200

Authors Sanad, SMH; Mekky, AEM in SPRINGER published article about ALZHEIMERS-DISEASE; BIOLOGICAL EVALUATION; DERIVATIVES; DRUG; BIS(2-S-ALKYLPYRIDINES); CHALCONES; DOCKING; MOIETY; QSAR in [Sanad, Sherif M. H.; Mekky, Ahmed E. M.] Cairo Univ, Fac Sci, Chem Dept, Giza 12613, Egypt in 2021.0, Cited 59.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Alzheimer’s disease is a degenerative brain condition that is the leading cause of dementia affecting millions of people around the world. Therapeutic development has focused on the problem of the loss of basal forebrain cholinergic function, as it is the only evidence responsible for brain neurodegeneration in patients with Alzheimer’s disease. Several attempts to improve cholinergic neurotransmission have been investigated by minimizing synaptic degradation of acetylcholine using acetylcholinesterase inhibitors. In the current study, we explore the designing of a new series of nicotinonitrile-coumarin hybrids as potential acetylcholinesterase inhibitors. The new hybrids were prepared utilizing pyridine-2(1H)-thiones as starting precursors. The in vitro acetylcholinesterase (AChE) inhibitory activities were examined for the new nicotinonitrile-coumarin hybrid molecules, when compared with donepezil as a standard drug with IC(50)of 14 nM. Coumarin derivative, linked to 6-(4-nitrophenyl)-4-phenylnicotinonitrile, showed more effective inhibitory activity than the reference donepezil with IC(50)of 13 nM. The free radical-scavenging capabilities against DPPH of the new hybrid derivatives were screened. Additionally, their in vitro cytotoxic activities have been tested against various eukaryotic cells. Furthermore, docking study showed excellent interaction between nicotinonitrile-coumarin hybrids and AChE. [GRAPHICS] .

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Sanad, SMH; Mekky, AEM or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about SELENOORGANIC COMPOUND EBSELEN; ANTIOXIDANT PROPERTIES; DIRECT SELENATION; C(SP(2))-H BONDS; ORGANOSELENIUM; THIOREDOXIN; INHIBITION; INDOLES; ACID; ARYL, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21776138, 21476116]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [30916011102, 30918011314]; Natural Science Foundation of JiangsuNatural Science Foundation of Jiangsu Province [BK20180476]; Qing Lan and Six Talent Peaks in Jiangsu Province; Priority Academic Program Development of Jiangsu Higher Education Institutions; Center for Advanced Materials and Technology at Nanjing University of Science and Technology. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Cao, Y; Liu, J; Liu, FM; Jiang, LQ; Yi, WB. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Name: 1-(4-Nitrophenyl)ethanone

A new method using a sodium selenite-based (NaO2SeR) direct selenylation reagent has been developed. NaO2SeR is odorless, shelf-stable, easy to handle, practical and scalable. Good yields and a broad functional group compatibility were observed when it was reacted with indoles, a furan, pyrrole and ketones under reductive conditions to afford the corresponding organoselenium products.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Cao, Y; Liu, J; Liu, FM; Jiang, LQ; Yi, WB or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. In 2020.0 POLYMERS-BASEL published article about ARAMIDS AROMATIC POLYAMIDES; POLYMERS; ACID in [Trigo-Lopez, Miriam; Sanjuan, Ana M.; Mendia, Aranzazu; Munoz, Asuncion; Garcia, Felix C.; Garcia, Jose M.] Univ Burgos, Fac Ciencias, Dept Quim, Plaza Misael Banuelos S-N, Burgos 09001, Spain in 2020.0, Cited 38.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

We prepared high-performance aromatic copolyamides, containing bithiazole and thiazolo-thiazole groups in their main chain, from aromatic diamines and isophthaloyl chloride, to further improve the prominent thermal behavior and exceptional mechanical properties of commercial aramid fibers. The introduction of these groups leads to aramids with improved strength and moduli compared to commercialmeta-oriented aromatic polyamides, together with an increase of their thermal performance. Moreover, their solubility, water uptake, and optical properties were evaluated in this work.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Trigo-Lopez, M; Sanjuan, AM; Mendia, A; Munoz, A; Garcia, FC; Garcia, JM or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases published in 2019.0. SDS of cas: 100-19-6, Reprint Addresses Menges, N (corresponding author), Van Yuzuncu Yil Univ, Pharmaceut Chem Sect, TR-65080 Van, Turkey.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Mono- or di-substituted imidazole derivatives were synthesized using a one-pot, two-step strategy. All imidazole derivatives were tested for AChE and BChE inhibition and showed nanomolar activity similar to that of the test compound donepezil and higher than that of tacrine. Structure activity relationship studies, docking studies to on X-ray crystal structure of AChE with PDB code 1B41, and adsorption, distribution, metabolism, and excretion (ADME) predictions were performed. The synthesized core skeleton was bound to important regions of the active site of AChE such as the peripheral anionic site (PAS), oxyanion hole (OH), and anionic subsite (AS). Selectivity of the reported test compounds was calculated and enzyme kinetic studies revealed that they behave as competitive inhibitors, while two of the test compounds showed noncompetitive inhibitory behavior. ADME predictions revealed that the synthesized molecules might pass through the blood brain barrier and intestinal epithelial barrier and circulate freely in the blood stream without binding to human serum albumin. While the toxicity of one compound on the WS1 (skin fibroblast) cell line was 1790 mu M, its toxicity on the SH-SY5Y (neuroblastoma) cell line was 950 mu M.

SDS of cas: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Kuzu, B; Tan, M; Taslimi, P; Gulcin, I; Taspinar, M; Menges, N or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Li, PG; Zhu, H; Fan, M; Yan, C; Shi, K; Chi, XW; Zou, LH in ROYAL SOC CHEMISTRY published article about DOUBLE CARBONYLATION; TERMINAL ALKYNES; C-H; ENANTIOSELECTIVE SYNTHESIS; OXIDATIVE AMIDATION; OXOCARBOXYLIC ACIDS; CHLOROPEPTIN-I; FKBP12 LIGANDS; ARYL IODIDES; DERIVATIVES in [Li, Ping-Gui; Zhu, Hao; Fan, Min; Yan, Cheng; Shi, Kai; Chi, Xi-Wen; Zou, Liang-Hua] Jiangnan Univ, Minist Educ, Sch Pharmaceut Sci, Key Lab Carbohydrate Chem & Biotechnol, Lihu Ave 1800, Wuxi 214122, Jiangsu, Peoples R China; [Li, Ping-Gui] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Xianlin Ave 163, Nanjing 210093, Jiangsu, Peoples R China in 2019.0, Cited 76.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Copper-catalyzed coupling of alpha-keto acids with anthranils is reported for the synthesis of alpha-ketoamides. This process involves N-O/C-O bond cleavages and C-N bond formation. Furthermore, the decarboxylation of alpha-keto acids can be successfully suppressed under redox-neutral conditions.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Li, PG; Zhu, H; Fan, M; Yan, C; Shi, K; Chi, XW; Zou, LH or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 CHINESE J STRUC CHEM published article about HOMOGENEOUS CATALYSIS; HETEROGENEOUS CATALYSTS; HYDROGENATION; PD; REDUCTION; NANOPARTICLES; NITROARENES; RECOVERY; LAYER; MONODISPERSE in [Chen Yan-Ning; Li Jing-Jun; Yang Wei-Guang] Fuzhou Univ, Coll Chem, Fuzhou 350002, Peoples R China; [Chen Yan-Ning; Li Jing-Jun; Yang Wei-Guang; Gao Shui-Ying] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China in 2020.0, Cited 34.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

This work presents a highly active and reusable heterogeneous film catalytic assembly for hydrogenation reduction of aromatic nitro compounds. The multilayer structures of PEI-(K2PdCl4-P1)(n)-film (PEI = polyethylenmine, P1 = 3-amino-3-(4-pyridinyl)-propionitrile) bound to quartz slides were fabricated by layer-by-layer (LbL) self-assembly method. Various characterization techniques including X-ray photoelectron spectroscopy (XPS), inductively coupled plasma OES spectrometer (ICP), UV-vis spectroscopy and atomic force microscopy (AFM) were employed to reveal the growth process of the resulting LbL multilayers in detail. Subsequent in situ reduction by H-2 produced Pd nanoparticles embedded in such films were used as catalyst for the hydrogenation of nitroarenes. The catalytic performance test shows that the thin film catalyst can be applied to the hydrogenation reaction of various substituted nitroaromatics, and exhibits good catalytic activity and good catalyst stability. It is worth mentioning that our catalytic films can be easily removed from the reaction system in any time during the reaction, and the catalytic activity could be fully recovered when reused directly in another catalytic cycle for five times.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Chen, YN; Li, JJ; Yang, WG; Gao, SY or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about REDUCTIVE DECYANATION; CATALYZED CYANATION; LITHIUM REAGENTS; METAL EXCHANGE; CHEMISTRY ARC; POTASSIUM; GRIGNARD; HYDROCYANATION; DERIVATIVES; ALKYLATIONS, Saw an article supported by the NSERCNatural Sciences and Engineering Research Council of Canada (NSERC); Canada Foundation for InnovationCanada Foundation for InnovationCGIAR [35261]; Ontario Research Fund; University of TorontoUniversity of Toronto. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Alazet, S; West, MS; Patel, P; Rousseaux, SAL. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile. HPLC of Formula: C14H11N

The efficient preparation of nitrile-containing building blocks is of interest due to their utility as synthetic intermediates and their prevalence in pharmaceuticals. As a result, significant efforts have been made to develop methods to access these motifs which rely on safer and non-toxic sources of CN. Herein, we report that 2-methyl-2-phenylpropanenitrile is an efficient, non-toxic, electrophilic CN source for the synthesis of nitrile-bearing quaternary centers by a thermodynamic transnitrilation and anion-relay strategy. This one-pot process leads to nitrile products resulting from the gem-difunctionalization of alkyl lithium reagents.

HPLC of Formula: C14H11N. Welcome to talk about 86-29-3, If you have any questions, you can contact Alazet, S; West, MS; Patel, P; Rousseaux, SAL or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthetic Approaches to Metallo-Supramolecular Co-II Polygons and Potential Use for H2O Oxidation WOS:000580381700067 published article about WATER-OXIDATION; COORDINATION CAGES; DISCRETE; CAPTURE; RELEASE; SPIN; ELECTROCATALYSTS; CATALYSIS; EXCHANGE in [Ako, Ayuk M.; Kathalikkattil, Amal Cherian; Elliott, Rory; Soriano-Lopez, Joaquin; McKeogh, Ian M.; Zubair, Muhammad; Zhu, Nianyong; Garcia-Melchor, Max; Schmitt, Wolfgang] Univ Dublin, Trinity Coll, Sch Chem, Dublin D02 PN40, Ireland; [Ako, Ayuk M.; Kathalikkattil, Amal Cherian; Elliott, Rory; Soriano-Lopez, Joaquin; McKeogh, Ian M.; Zubair, Muhammad; Zhu, Nianyong; Garcia-Melchor, Max; Schmitt, Wolfgang] Univ Dublin, Trinity Coll, AMBER Ctr, Dublin D02 PN40, Ireland; [Kruger, Paul E.] Univ Canterbury, Sch Phys & Chem Sci, MacDiarmid Inst Adv Mat & Nanotechnol, Christchurch 8041, New Zealand in 2020.0, Cited 45.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

Metal-directed self-assembly has been applied to prepare supramolecular coordination polygons which adopt tetrahedral (1) or trigonal disklike topologies (2). In the solid state, 2 assembles into a stable halide-metal-organic material (Hal-MOM-2), which catalyzes H2O oxidation under photo- and electrocatalytic conditions, operating with a maximum TON = 78 and TOF = 1.26 s(-1). DFT calculations attribute the activity to a Co-III-oxyl species. This study provides the first account of how Co-II imine based supramolecules can be employed as H2O oxidation catalysts.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ako, AM; Kathalikkattil, AC; Elliott, R; Soriano-Lopez, J; McKeogh, IM; Zubair, M; Zhu, NY; Garcia-Melchor, M; Kruger, PE; Schmitt, W or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Acid-Catalyzed Pseudo Five-Component Annulation for a General One-Pot Synthesis of 2,4,6-Triaryl Pyrimidines published in 2020.0. Computed Properties of C8H7NO3, Reprint Addresses Ma, YM (corresponding author), Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China.; Ma, YM (corresponding author), Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A facile and general synthesis of 2,4,6-triaryl pyrimidines has been developed. It involves a one-pot [2+1+1+1+1] pseudo five-component annulation of one methyl ketone, two aldehydes and two NH4OAc catalyzed by TfOH. One C-C and four C-N bonds are formed during the oxidative annulation process. The reaction shows good tolerance of many important functional groups in air and produces only water as the coproduct, making this methodology a highly versatile alternative to the existing methods for structuring pyrimidine framework.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ding, YX; Ma, RC; Hider, RC; Ma, YM or concate me.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Uranium versus Thorium: Synthesis and Reactivity of [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U[eta(2)-C2Ph2] WOS:000629388600001 published article about CHEMISTRY; COMPLEXES in [Wang, Deqiang; Ding, Wanjian; Hou, Guohua; Zi, Guofu] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China; [Walter, Marc D.] Tech Univ Carolo Wilhelmina Braunschweig, Inst Anorgan & Analyt Chem, Hagenring 30, D-38106 Braunschweig, Germany in 2021, Cited 121. Category: benzodioxans. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

The synthesis, electronic structure, and reactivity of a uranium metallacyclopropene were comprehensively studied. Addition of diphenylacetylene (PhC equivalent to CPh) to the uranium phosphinidene metallocene [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U=P-2,4,6-tBu(3)C(6)H(2) (1) yields the stable uranium metallacyclopropene, [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U[eta(2)-C2Ph2] (2). Based on density functional theory (DFT) results the 5f orbital contributions to the bonding within the metallacyclopropene U-(eta(2)-C=C) moiety increases significantly compared to the related Th-IV compound [eta(5)-1,2,4-(Me3C)(3)C5H2](2)Th[eta(2)-C2Ph2], which also results in more covalent bonds between the [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U2+ and [eta(2)-C2Ph2](2-) fragments. Although the thorium and uranium complexes are structurally closely related, different reaction patterns are therefore observed. For example, 2 reacts as a masked synthon for the low-valent uranium(II) metallocene [eta(5)-1,2,4-(Me3C)(3)C5H2](2)U-II when reacted with Ph2E2 (E=S, Se), alkynes and a variety of hetero-unsaturated molecules such as imines, ketazine, bipy, nitriles, organic azides, and azo derivatives. In contrast, five-membered metallaheterocycles are accessible when 2 is treated with isothiocyanate, aldehydes, and ketones.

Category: benzodioxans. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Wang, DQ; Ding, WJ; Hou, GH; Zi, GF; Walter, MD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem