Tag: M.W=150-200

An article Novel thiazole-piperazine derivatives as potential cholinesterase inhibitors WOS:000485774300001 published article about TARGET-DIRECTED LIGANDS; BIOLOGICAL EVALUATION; ANTICHOLINESTERASE ACTIVITY; MOLECULAR DOCKING; IN-SILICO; DESIGN; ACETYLCHOLINESTERASE; BUTYRYLCHOLINESTERASE; HYBRIDS; DONEPEZIL in [Demirayak, Seref; Sahin, Zafer; Ertas, Merve; Bulbul, Emre Fatih; Bender, Ceysu; Berk, Barkin] Istanbul Medipol Univ, Sch Pharm, Dept Pharmaceut Chem, TR-34083 Istanbul, Turkey; [Biltekin, Sevde Nur] Istanbul Medipol Univ, Sch Pharm, Dept Pharmaceut Microbiol, TR-34083 Istanbul, Turkey; [Saglik, Begum Nurpelin; Levent, Serkan; Yurttas, Leyla] Anadolu Univ, Fac Pharm, Dept Pharmaceut Chem, TR-26470 Eskisehir, Turkey in 2019.0, Cited 46.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Dementia is a cognitive disorder mostly associated with Alzheimer’s disease (AD) in addition to being seen in many other diseases of the central nervous system (CNS). The limited number of drugs is not sufficient to provide adequate improvement to increase the quality of life of patients suffering from this symptom; therefore, all treatment options should be evaluated in detail. In this study, new molecules, [2-(4-(2/3/4-substituted phenyl)piperazin-1-yl)-4-phenylthiazol-5-yl][3/4-substituted phenyl]methanone derivatives (1-44), were obtained and analyzed in terms of their anticholinesterase activities. Kinetic mode and molecular interactions were also evaluated. An enzyme inhibition study was undertaken on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) using the Ellman method. Maestro program was used in molecular modeling studies. Forty-four compounds were evaluated on AChE and BChE enzymes at 10(-3) and 10(-4) concentrations. The inhibition concentrations were calculated as 0.268 mu M to 2.104 mu M for six compounds (4, 5, 16, 27, 37, and 38) on AChE. Compound 5 including the 4-methoxy substituent (IC50: 0.268 mu M) and compound 38 containing the 4-methoxy and 3-methyl substituents (IC50: 0.286 mu M) showed the highest AChE inhibitory activity. They were further examined in terms of hydrogen bonding with Arg296 and Ar-Ar interaction with Trp286. The activity of compound 5 was also assessed in mixed-type kinetic mode.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Demirayak, S; Sahin, Z; Ertas, M; Bulbul, EF; Bender, C; Biltekin, SN; Berk, B; Saglik, BN; Levent, S; Yurttas, L or concate me.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 2,2-Diphenylacetonitrile. Authors Zhou, YL; Xu, XJ; Sun, HW; Tao, GY; Chang, XY; Xing, XY; Chen, B; Xu, C in NATURE RESEARCH published article about in [Zhou, Yali; Xu, Xingjun; Sun, Hongwei; Tao, Guanyu; Chang, Xiao-Yong; Xing, Xiangyou; Xu, Chen] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen, Guangdong, Peoples R China; [Zhou, Yali; Xu, Xingjun; Sun, Hongwei; Tao, Guanyu; Chang, Xiao-Yong; Xing, Xiangyou; Xu, Chen] Southern Univ Sci & Technol, Dept Chem, Guangdong Prov Key Lab Catalysis, Shenzhen, Guangdong, Peoples R China; [Chen, Bo] Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen, Guangdong, Peoples R China in 2021, Cited 66. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

Hydrofunctionalization, the direct addition of an X-H (e.g., X=O, N) bond across an alkene, is a desirable strategy to make heterocycles that are important structural components of naturally occurring molecules. Described here is the design and discovery of donor-acceptor-type platinum catalysts that are highly effective in both hydroalkoxylation and hydroamination of unactivated alkenes over a broad range of substrates under mild conditions. A number of alkene substitution patterns are accommodated, including tri-substituted, 1,1-disubstituted, (E)-disubstituted, (Z)-disubstituted and even mono-substituted double bonds. Detailed mechanistic investigations suggest a plausible pathway that includes an unexpected dissociation/re-association of the electron-deficient ligand to form an alkene-bound donor-acceptor-type intermediate. These mechanistic studies help understand the origins of the high reactivity exhibited by the catalytic system, and provide a foundation for the rational design of chiral catalysts towards asymmetric hydrofunctionalization reactions. The direct addition of an O-H (hydroalkoxylation) or an N-H (hydroamination) bond across an alkene is a useful strategy to access biologically relevant heterocycles. Here, the authors report donor-acceptor-type platinum catalysts that are effective for both hydroalkoxylation and hydroamination of unactivated alkenes, with broad substrate scope and use of mild conditions.

Safety of 2,2-Diphenylacetonitrile. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Zhou, YL; Xu, XJ; Sun, HW; Tao, GY; Chang, XY; Xing, XY; Chen, B; Xu, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Xu, CY; Li, Q; Zhang, QY; Li, KJ; Yin, HF; Zhou, SH in AMER CHEMICAL SOC published article about NOBLE-METALS; HYDROGENATION; CO; OXIDATION; PD; ADSORPTION; NANOSHEETS; CARBON; SN; ELECTROCATALYSTS in [Xu, Caiyun; Li, Qi; Zhang, Qiuyang; Li, Kaijie; Zhou, Shenghu] East China Univ Sci & Technol, Sch Chem Engn, Shanghai Key Lab Multiphase Mat Chem Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China; [Yin, Hongfeng] Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, 1219 Zhongguan West Rd, Ningbo 315201, Zhejiang, Peoples R China in 2019.0, Cited 55.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

This work illustrates direct evidence of the formation of close-contact Rh-SnO2 heteroaggregate interfaces, and their enhanced catalytic hydrogenation performance is also demonstrated. Alumina-supported Rh-SnO2 heteroaggregate nanocatalysts were prepared by in situ transformation of Rh@Sn core-shell nanostructures. Various characterization techniques, especially the studies of high angle annular dark field scanning transition electron microscopy with phase mappings, confirm that Rh-SnO2 close-contact heteroaggragate nanostructures were obtained by in situ calcination and following reduction of Rh@Sn core-shell nanoparticle precursors. The catalytic studies for hydrogenations of various substituted nitroaromatics show that the Rh-SnO2/Al2O3 heteroaggregate nanocatalysts not only improve the catalytic conversions but also enhance the catalytic selectivity. The combination of characterization and catalytic studies suggests that a synergistic effect originated from close-contact Rh-SnO2 heteroaggregate interfaces exists in the Rh-SnO2 system, which enhances their catalytic hydrogenation performance.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Xu, CY; Li, Q; Zhang, QY; Li, KJ; Yin, HF; Zhou, SH or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about DEFECTIVE GRAPHENE; ELECTROCATALYTIC ACTIVITY; REDUCTION; CATALYSTS; FRAMEWORKS; EVOLUTION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21306132]. Recommanded Product: 1-(4-Nitrophenyl)ethanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Li, GZ; Zheng, SY; Wang, L; Zhang, XW. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Chemoselective hydrogenation of nitroarenes to anilines is of great importance for the manufacture of pharmaceuticals, fine chemicals, and dyes. In this study, a series of metal-free N-doped carbon nanotubes (NCNTs) have been prepared by the carbonization of in situ polymerized pyrrole on CNTs. The concentration of pyrrole, pyrolysis temperature, and the outside diameter of CNTs were investigated to improve the catalytic performance. As characterized by Raman and X-ray photoelectron spectroscopy (XPS), the optimal catalyst (NCNTs-800) possessed a unique structure doped with the same content of pyrrolic N and graphitic N. The activity and selectivity of NCNTs-800 have been evaluated for the selective hydrogenation of substituted nitroarenes. Highly selective hydrogenation of the nitro group of 12 different substrates has been achieved on NCNTs-800, even in the presence of a fragile iodo group. The hydrogenation reaction on N-doped CNTs from polypyrrole involved a mixture of different hydrogen species including nonpolar H radicals. In addition, stability and recyclability of NCNTs-800 have been tested.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, GZ; Zheng, SY; Wang, L; Zhang, XW or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Access to Sulfides through Free Radical Reaction of Vinyl Halides with Thiols published in 2019.0. Product Details of 100-19-6, Reprint Addresses Shi, ZF; Cao, XP (corresponding author), Lanzhou Univ, State Key Lab Appl Organ Chem, 222 Tianshui Rd, Lanzhou 730000, Gansu, Peoples R China.; Shi, ZF; Cao, XP (corresponding author), Lanzhou Univ, Coll Chem & Chem Engn, 222 Tianshui Rd, Lanzhou 730000, Gansu, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

An efficient radical-mediated carbon-sulfur bond formation reaction of vinyl halides with thiols has been developed. This reaction tolerated vinyl chloride substrates, which are barely tolerated in metal-catalyzed reactions, providing vinyl sulfide products. When vinyl iodides were used as substrates, the reactions were regulated by the solvents, yielding vinyl sulfide products in protic solvents (methanol) and alkyl sulfides in aprotic solvents (toluene).

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shi, ZF; Xu, LN; Chen, J; Luo, HX; Zhang, JT; Cao, XP or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article CO2-Folded Single-Chain Nanoparticles as Recyclable, Improved Carboxylase Mimics published in 2020.0. Formula: C8H7NO3, Reprint Addresses Yan, Q (corresponding author), Fudan Univ, Dept Macromol Sci, State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Emulating the function of natural carboxylases to convert CO(2)under atmospheric condition is a great challenge. Herein we report a class of CO2-folded single-chain nanoparticles (SCNPs) that can function as recyclable, function-intensified carboxylase mimics. Lewis pair polymers containing bulky Lewis acidic and basic groups as the precursor, can bind CO(2)to drive an intramolecular folding into SCNPs, in which CO(2)as the folded nodes can form gas-bridged bonds. Such bridging linkages highly activate CO2, which endows the SCNPs with extraordinary catalytic ability that can not only catalyze CO2-insertion of C(sp(3))-H for imitating the natural enzyme’s function, it can also act on non-natural carboxylation pathways for C(sp(2)and sp)-H substrates. The nanocatalysts are of highly catalytic efficiency and recyclability, and can work at room temperature and near ambient CO(2)condition, inspiring a new approach to sustainable C(1)utilization.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zeng, RJ; Chen, L; Yan, Q or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. In 2021.0 NANO RES published article about DOPED CARBON; IN-SITU; HYDROGENATION; CATALYSTS; RECOGNITION; HYDROGELS; DESIGN in [Shen, Yajing; Zheng, Qingshu; Liu, Jianhong; Tu, Tao] Fudan Univ, Shanghai Key Lab Mol Catalysis & Innovat Mat, Dept Chem, 2005 Songhu Rd, Shanghai 200438, Peoples R China; [Tu, Tao] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China; [Tu, Tao] Zhengzhou Univ, Coll Chem & Mol Engn, 100 Kexue Ave, Zhengzhou 450001, Peoples R China in 2021.0, Cited 59.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A series of robust metallo-aerogels are readily fabricated by pyrolysis of xerogels derived from chitosan-metal (M = Fe, Co, Ni) hydrogels. Owing to the strong coordination between metal ions and the functional groups (NH2 and OH) of chitosan, metallo-aerogels consisting of encapsulated metal-nanoparticles (MNPs) by graphite shells were obtained, as supported by various characterizations including high-resolution transmission electron microscope (HR-TEM), X-ray diffraction (XRD), and Raman. The resulting metallo-aerogels could be functioned as highly stable, efficient and selective nanocatalysts towards the hydrogenation of nitroarenes to amines at low catalyst loading (1.2 mol.%-2.4 mol.%). Remarkably, the metallo-aerogels could be reused for more than 30 runs without obvious loss of activity and selectivity. These distinguished performances were attributed to the graphitic shells formed during the pyrolysis, which hampered the possible aggregation of MNPs, prevented metal leaching and increased their stability.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shen, YJ; Zheng, QS; Liu, JH; Tu, T or concate me.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors El-sayed, HA; Assy, MG; Mohamed, AS in WILEY-V C H VERLAG GMBH published article about in [El-sayed, Hassan A.; Assy, Mohamed G.; Mohamed, Asaad S.] Zagazig Univ, Fac Sci, Dept Chem, Zagazig 44519, Egypt in 2019.0, Cited 15.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

An efficient and facile approach has been described for the synthesis of a new series of 1-amino-2-oxo-nicotinonitriles and their sulfonamides under microwave and ultrasonic irradiation. The desired compounds 4 a-l were obtained via condensation of p-chlorobenzaldehyde, aryl or heteroaryl methyl ketone and cyanoacetohydrazide in the presence of catalytic piperidine under three synthetic methodologies (namely, conventional method, ultrasonic and microwave irradiation), the best results (short reaction times, pure products, high yield) were obtained by ultrasonic irradiation. Sulfonamides 5 a-f resulted via reaction of amines 4 a-e and 4 j with benzene sulfonyl chloride in the presence of pyridine. The synthesized compounds give no significant results when investigated against Gm (+ve) and Gm (-ve) bacteria, and fungi strains.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact El-sayed, HA; Assy, MG; Mohamed, AS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 FIBER POLYM published article about OPTICAL TRANSPARENCY; SOLUBLE POLYIMIDES; PYRIDINE; PROTONATION; SOLUBILITY; DIANHYDRIDE; METHANE; UNITS in [Huang, Xiaohua; Li, Hua; Liu, Chanjuan; Zang, Limin; Zhou, Huanfu; Wei, Chun] Guilin Univ Technol, Key Lab New Proc Technol Nonferrous Met & Mat, Collaborat Innovat Ctr Explorat Hidden Nonferrous, Minist Educ,Sch Mat Sci & Engn, Guilin 541004, Peoples R China in 2019.0, Cited 30.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

A novel diamine monomer 4-(4-diethylaminophenyl)-2,6-bis(4-aminophenyl)pyridine (APAP) was successfully synthesized, and then a series of poly(pyridine imide)s was prepared from APAP with five commercial dianhydrides: pyromellitic dianhydride (PMDA), 3,3,4,4-biphenyltetracarboxylic dianhydride (BPDA), 4,4-oxydiphthalic anhydride (ODPA), 3,3,4,4-benzophenone tetracarboxylic dianhydride (BTDA), and 4,4-(hexafluoroisopropylidene)diphthalic anhydride (6FDA) via a two-step solution polycondensation method. The structure of APAP was characterized by FT-IR, NMR, and MS. The resulting polymers have good solubility in polar solvents, such as NMP, DMF, and DMSO. Furthermore, they exhibited outstanding thermal stability. The glass transition temperature (T-g) of polymers range from 326 to 346 degrees C, and the temperature at 5 % and 10 % weight loss in the range of 527 degrees C to 570 degrees C and 550 degrees C to 601 degrees C, respectively. Moreover, they also presented excellent hydrophobicity with contact angels in the range of 88.4 degrees to 94.0 degrees.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Huang, XH; Li, H; Liu, CJ; Zang, LM; Zhou, HF; Wei, C or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about H ACTIVATION; POLYETHYLENE-GLYCOL; ORGANIC-SYNTHESIS; INTERNAL ALKYNES; DIRECTING GROUP; EFFICIENT SYNTHESIS; IRIDIUM COMPLEXES; O BOND; FUNCTIONALIZATION; RHODIUM, Saw an article supported by the University Grants Commission (UGC), New Delhi, IndiaUniversity Grants Commission, India [F.25-1/2014-15, F.7-227/2009]. Formula: C8H7NO3. Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Deshmukh, DS; Bhanage, BM. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

In this work, N-Cbz hydrazone has been employed as a rarely explored directing group for the synthesis of isoquinolines by annulation with internal alkynes via C-H/ N-N activation using Ru catalyst. Additive as well as external oxidant-free rapid protocol has been established for the synthesis of isoquinolines using microwave strategy. Use of non-volatile and biodegradable PEG as a green solvent with lower catalyst loading makes the proposed protocol environmentally benign. Further, higher functional group tolerance and wide substrate scope has been observed under the stated methodology with higher yields.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Deshmukh, DS; Bhanage, BM or concate me.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem