Tag: M.W=150-200

An article An Expedient, Direct, Three-Component Approach for the Synthesis of 4-Thioarylpyrroles WOS:000490882000011 published article about HIGHLY SUBSTITUTED PYRROLES; OXIDATIVE ANNULATION; REGIOSELECTIVE SULFENYLATION; POLYSUBSTITUTED PYRROLES; ONE-POT; ATORVASTATIN; DERIVATIVES; INHIBITORS; FUNCTIONALIZATION; CONSTRUCTION in [Rajeshkumar, Venkatachalam; Neelamegam, Chinnaraj; Anandan, Sambandam] Natl Inst Technol Tiruchirappalli, Dept Chem, Tiruchirappalli 620015, Tamil Nadu, India in 2019.0, Cited 75.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. COA of Formula: C8H7NO3

A three-component strategy for the synthesis of 4-thioarylpyrroles from 1,4-enediones, thiols, and ammonium formate in one-pot has been developed. The reaction proceeds through the sequential thiol-Michael/Paal-Knorr reaction of 1,4-enediones with the formation of one new C-S and two C-N bonds. The operationally simple protocol provides direct access to the highly functionalized 4-thioarylpyrroles with free-NH in good to excellent yields. The synthetic application of resulting 4-thioarylpyrroles was demonstrated by oxidation of the sulfur atom to the corresponding sulfoxide and sulfone.

COA of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Rajeshkumar, V; Neelamegam, C; Anandan, S or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Chen, C; Zhang, X; Cao, HG; Wang, F; Yu, L; Xu, Q in WILEY-V C H VERLAG GMBH published article about CARBONYL-COMPOUNDS; HYDROGEN-PEROXIDE; SELENIUM; EFFICIENT; OXIMES; ALKENES; FUNCTIONALIZATION; DEPROTECTION; ALDOXIMES; CLEAVAGE in [Chen, Chao; Zhang, Xu; Cao, Hongen; Wang, Fang; Yu, Lei; Xu, Qing] Yangzhou Univ, Sch Chem & Chem Engn, Guangling Coll, Yangzhou 225002, Jiangsu, Peoples R China; [Chen, Chao; Zhang, Xu; Cao, Hongen; Wang, Fang; Yu, Lei; Xu, Qing] Yangzhou Univ, Sch Hort & Plant Protect, Inst Pesticide, Yangzhou 225002, Jiangsu, Peoples R China; [Wang, Fang] Yangzhou Polytechnol Inst, Yangzhou 225127, Jiangsu, Peoples R China; [Xu, Qing] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Zhejiang, Peoples R China in 2019.0, Cited 68.0. HPLC of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In contrast to conventional organoselenium-catalyzed oxidation reactions that require peroxide oxidants such as hydrogen peroxide, in this work we found that, addition of a low loading of iron (II) could enable the successful utilization of air as the terminal oxidant in organoselenium-catalyzed oxidative deoximation reaction of ketoximes. This led to a new mild and relatively green aerobic oxidative deoximation method. Control reactions and X-ray photoelectron spectroscopy (XPS) analysis suggest that iron is crucial in the catalytic cycle, working to prohibit the deactivation of selenium catalyst through an iron-catalyzed aerobic oxidation of low valent selenium species by air to the active high valent selenium species. Since air can be utilized as the terminal oxidant, this work may contribute to the advance of organoselenium catalysis.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chen, C; Zhang, X; Cao, HG; Wang, F; Yu, L; Xu, Q or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. In 2019.0 J MOL STRUCT published article about HETEROGENEOUS CATALYST; COPPER; NANOPARTICLES; DIARYL; SUPPORT; HYBRID in [Monjezi, Homeyra Rostami; Safari, Javad] Univ Kashan, Fac Chem, Dept Organ Chem, Kashan 8731751167, Iran; [Zarnegar, Zohre] Univ Payame Noor, Dept Chem, POB 19395-4697, Tehran, Iran in 2019.0, Cited 29.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Novel arginine-functionalized starch-based nanoparticles (Arg-SNPs) were synthesized and characterized by Fourier transforms infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX), X-ray diffraction (XRD) and thermos-gravimetric analyses (TGA) techniques. Arg-SNP was used as a highly efficient and macromolecule-supported recyclable nanocatalyst for the one-pot reaction between thiourea and iodine with various substituted methylcarbonyls to afford the corresponding diheteroaryl thioethers in high-to-quantitative yields. The nanocatalyst was recycled at least five times without significant decrease in the catalytic activity. (C) 2019 Elsevier B.V. All rights reserved.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zarnegar, Z; Monjezi, HR; Safari, J or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Preparation of highly dispersed Ru nanoparticles supported on amine-functionalized magnetic nanoparticles: Efficient catalysts for the reduction of nitro compounds WOS:000530690600002 published article about TRANSFER HYDROGENATION; AROMATIC-COMPOUNDS; PD NANOPARTICLES; GRAPHENE OXIDE; AMMONIA BORANE; CARBON; NITROARENES in [Liu, Yue; Yin, Defu; Xin, Qianghua; Lv, Mingxin; Xie, Congxia; Yu, Shitao; Liu, Shiwei] Qingdao Univ Sci & Technol, Coll Chem Engn, State Key Lab Base Ecochem Engn, 53 Zhengzhou Rd, Qingdao 266042, Peoples R China; [Bian, Bing] Shandong Univ Sci & Technol, Coll Chem & Environm Engn, Qingdao 266590, Peoples R China; [Li, Lu] Qingdao Univ Sci & Technol, Coll Marine Sci & Biol Engn, 53 Zhengzhou Rd, Qingdao 266042, Peoples R China in 2020.0, Cited 35.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Computed Properties of C8H7NO3

A supported ruthenium (Ru) nanoparticle on amino-functionalized Fe3O4 (Fe3O4/NH2/Ru) was successfully prepared by a novel and simple one-pot template-free method combined with a metal adsorption-reduction procedure. The characterization results show that the introduced amino group (1,6-hexanediamine) can effectively stabilize the Ru nanoparticles and allow the particles to maintain a narrow size distribution, monodispersity and a regular morphology. Fe3O4/NH2/Ru exhibits excellent catalytic activity for the transfer hydrogenation of nitro compounds by the use of NaBH4 as the hydrogen donor. The higher activity of this catalyst was attributed to the higher dispersion and smaller particle size of Ru nanoparticles, as observed from the characterization results. Moreover, the catalyst can be easily recovered by an external magnetic field, recycled five times and reused without any loss of activity.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Liu, Y; Yin, DF; Xin, QH; Lv, MX; Bian, B; Li, L; Xie, CX; Yu, ST; Liu, SW or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Lin, JS; Li, TT; Jiao, GY; Gu, QS; Cheng, JT; Lv, L; Liu, XY in [Lin, Jin-Shun] Tsinghua Univ, Key Lab Chem Biol, State Key Lab Chem Oncogen, Grad Sch Shenzhen, Shenzhen 518055, Peoples R China; [Lin, Jin-Shun] Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China; [Lin, Jin-Shun; Li, Tao-Tao; Jiao, Guan-Yuan; Gu, Qiang-Shuai; Cheng, Jiang-Tao; Lv, Ling; Liu, Xin-Yuan] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China; [Lin, Jin-Shun; Li, Tao-Tao; Jiao, Guan-Yuan; Cheng, Jiang-Tao; Lv, Ling; Liu, Xin-Yuan] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China; [Gu, Qiang-Shuai] Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen 518055, Peoples R China published Chiral BrOnsted Acid Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes in 2019, Cited 71. Name: 2,2-Diphenylacetonitrile. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

The first highly efficient and practical chiral BrOnsted acid catalyzed dynamic kinetic asymmetric hydroamination (DyKAH) of racemic allenes and asymmetric hydroamination of unactivated dienes with both high E/Z selectivity and enantioselectivity are described herein. The transformation proceeds through a new catalytic asymmetric model involving a highly reactive pi-allylic carbocationic intermediate, generated from racemic allenes or dienes through a proton transfer mediated by an activating/directing thiourea group. This method affords expedient access to structurally diverse enantioenriched, potentially bioactive alkenyl-containing aza-heterocycles and bicyclic aza-heterocycles.

Name: 2,2-Diphenylacetonitrile. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Lin, JS; Li, TT; Jiao, GY; Gu, QS; Cheng, JT; Lv, L; Liu, XY or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. I found the field of Chemistry very interesting. Saw the article Convenient One-Pot Synthesis of Allylsilanes from Enolizable Ketones published in 2019.0, Reprint Addresses Kwan, MLD (corresponding author), John Carroll Univ, Dept Chem, 1 John Carroll Blvd, University Hts, PA 44118 USA.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

A convenient one-pot synthesis of allylsilanes from enolizable methyl aryl ketones has been developed. The first step involves nucleophilic addition of the trimethylsilylmethyl group to ketones using the alkylation method developed by Ishihara with slight modification to generate the corresponding beta-silylalkoxides. The second step entails addition of diisobutylaluminum chloride and heating at about 130 degrees C overnight to afford allylsilanes in fair yields.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Kwan, MLD; Challen, PR; Tran, QDD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Nickel Chloride-Catalyzed Oxidation of Aromatic Hydrocarbon with Sodium Persulfate at the Benzylic Site WOS:000473263100018 published article about H BOND OXIDATION; SELECTIVE OXIDATION; ACTIVATION; TOLUENE; OXYGENATION; OZONE in [Liu, Lice; Wu, Jieqing; Ma, Hongfei; Gu, Jiefan; Li, Yufeng] Nanjing Tech Univ, Coll Chem & Mol Engn, Nanjing 210036, Jiangsu, Peoples R China; [Zhang, Han] Nanjing UNOCI Chem Co, Nanjing 210009, Jiangsu, Peoples R China in 2019.0, Cited 49.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

A practical method for the oxidation of aromatic side chains was established for the preparation of aromatic aldehydes and ketones. Using NiCl2 as the catalyst, substituted toluenes were oxidized with Na2S2O8 at the benzvlic site for the synthesis of the corresponding aldehydes in the yield of 22%similar to 79%. Ethylbenzene analogs were oxidized more easily to obtain the corresponding ketones with 64%similar to 84% yields. The oxidation of benzyl alcohol analogs was completed to acquire the corresponding carbonyl compounds in shorter time with better selectivity and yields. The method has the advantages such as the mild reaction conditions, no requirement for precious metals or additional promoter, and good selectivity.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Liu, LC; Wu, JQ; Ma, HF; Zhang, H; Gu, JF; Li, YF or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. In 2020 ANGEW CHEM INT EDIT published article about SELECTIVE HYDROGENATION; REDUCTION; BENZIMIDAZOLES; NANOPARTICLES; DERIVATIVES; DISCOVERY; AFFINITY; IMINES; POTENT; AGENTS in [Ryabchuk, Pavel; Leischner, Thomas; Kreyenschulte, Carsten; Spannenberg, Anke; Junge, Kathrin; Beller, Matthias] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany in 2020, Cited 50. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A bifunctional 3d-metal catalyst for the cascade synthesis of diverse pyrroles from nitroarenes is presented. The optimal catalytic system Co/NGr-C@SiO2-L is obtained by pyrolysis of a cobalt-impregnated composite followed by subsequent selective leaching. In the presence of this material, (transfer) hydrogenation of easily available nitroarenes and subsequent Paal-Knorr/Clauson-Kass condensation provides >40 pyrroles in good to high yields using dihydrogen, formic acid, or a CO/H2O mixture (WGSR conditions) as reductant. In addition to the favorable step economy, this straightforward domino process does not require any solvents or external co-catalysts. The general synthetic utility of this methodology was demonstrated on a variety of functionalized substrates including the preparation of biologically active and pharmaceutically relevant compounds, for example, (+)-Isamoltane.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ryabchuk, P; Leischner, T; Kreyenschulte, C; Spannenberg, A; Junge, K; Beller, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Wei, ZY; Ru, S; Zhao, QX; Yu, H; Zhang, G; Wei, YG in [Wei, Zheyu; Ru, Shi; Zhao, Qixin; Yu, Han] Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China; [Yu, Han; Wei, Yongge] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China; [Zhang, Gang] Sichuan Univ, Inst Mat Sci & Technol, Chengdu 610064, Sichuan, Peoples R China; [Zhang, Gang] Sichuan Univ, Analyt & Testing Ctr, Chengdu 610064, Sichuan, Peoples R China published Highly efficient and practical aerobic oxidation of alcohols by inorganic-ligand supported copper catalysis in 2019.0, Cited 66.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The oxidation of alcohols to aldehydes or ketones is a highly relevant conversion for the pharmaceutical and fine-chemical industries, and for biomass conversion, and is commonly performed using stoichiometric amounts of highly hazardous oxidants. The aerobic oxidation of alcohols with transition metal complex catalysts previously required complicated organic ligands and/or nitroxyl radicals as co-catalysts. Herein, we report an efficient and eco-friendly method to promote the aerobic oxidation of alcohols using an inorganic-ligand supported copper catalyst 1, (NH4)(4)[CuMo6O18(OH)(6)], with O-2 (1 atm) as the sole oxidant. Catalyst 1 is synthesized directly from cheap and commonly available (NH4)(6)Mo7O24 center dot 4H(2)O and CuSO4, which consists of a pure inorganic framework built from a central Cu-II core supported by six (MoO6)-O-VI inorganic scaffolds. The copper catalyst 1 exhibits excellent selectivity and activity towards a wide range of substrates in the catalytic oxidation of alcohols, and can avoid the use of toxic oxidants, nitroxyl radicals, and potentially air/moisture sensitive and complicated organic ligands that are not commercially available. Owing to its robust inorganic framework, catalyst 1 shows good stability and reusability, and the catalytic oxidation of alcohols with catalyst 1 could be readily scaled up to gram scale with little loss of catalytic activity, demonstrating great potential of the inorganic-ligand supported Cu catalysts in catalytic chemical transformations.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wei, ZY; Ru, S; Zhao, QX; Yu, H; Zhang, G; Wei, YG or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 BIOORG CHEM published article about PROLIFERATOR-ACTIVATED RECEPTORS; CYCLOOXYGENASE-2 INHIBITORS; MOLECULAR DOCKING; INFLAMMATION; GLUCOSIDASE; REGULATOR; DISCOVERY; ANALOGS; RAT in [Abdellatif, Khaled R. A.; Fadaly, Wael A. A.] Beni Suef Univ, Fac Pharm, Pharmaceut Organ Chem Dept, Bani Suwayf, Egypt; [Abdellatif, Khaled R. A.] Ibn Sina Natl Coll Med Studies, Pharmaceut Sci Dept, Jeddah 21418, Saudi Arabia; [Kamel, Gehan M.] Cairo Univ, Fac Vet, Pharmacol Dept, Cairo, Egypt; [Elshaier, Yaseen A. M. M.] Al Azhar Univ, Pharmaceut Organ Chem Dept, Fac Pharm, Assiut 71524, Egypt; [El-Magd, Mohammed A.] Kafrelshiekh Univ, Anat Dept, Fac Vet Med, Kafrelshiekh 33516, Egypt in 2019.0, Cited 51.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Nowadays, diabetes and its associated inflammatory complications are important public health problems worldwide. Market limitations of drugs with dual actions as anti-inflammatory (AI) and anti-diabetic have been led to a temptation for focusing on the discovery and development of new compounds with potential AI and antidiabetic activities. Herein, we synthesized two new series containing pyrazole ring with vicinal diaryl rings as selective COX-2 moiety and thiazolidindione (series 12a-f) or thiazolidinone (series 13a-f) as anti-diabetic moiety and the two moieties were linked together with methylene or methylenehydrazone functionality. The two series were evaluated for their COX inhibition, AI activity and ulcerogenic liability and for the anti-diabetic activity; 12a-f and 13a-f were assessed in vitro against alpha-glucosidase, beta-glucosidase, in vivo hypoglycemic activity (one day and 15 days studies) in addition to PPAR. activation study. Four compounds (12c, 12f, 13b and 13f) had higher COX-2 S.I. (8.69-9.26) than the COX-2 selective drug celecoxib (COX-2 S.I. = 8.60) and showed the highest AI activities and the lowest ulcerogenicity than other derivatives. Also, two thiazolidindione derivatives 12e and 12f and two thiazolidinone derivatives 13b and 13c showed higher inhibitory activities against alpha- and beta-glucosidase (% inhibitory activity = 62.15, 55.30, 65.37, 59.08 for alpha-glucosidase and 57.42, 60.07, 58.19, 66.90 for beta-glucosidase respectively) than reference compounds (acarbose with % inhibitory activity = 49.50 for alpha-glucosidase and D-saccharic acid 1,4-lactone monohydrate with % inhibitory activity = 53.42 for beta-glucosidase) and also showed good PPAR-gamma activation and good hypoglycemic effect in comparison to pioglitazone and rosiglitazone. Moreover, Shape comparison and docking studies were carried out to understand their interaction and similarity with standard drugs.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Abdellatif, KRA; Fadaly, WAA; Kamel, GM; Elshaier, YAMM; El-Magd, MA or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem