Tag: M.W=150-200

An article Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment WOS:000526402700030 published article about TRYPANOSOMA-BRUCEI; PUMPING PYROPHOSPHATASES; ACIDOCALCISOMES; BISPHOSPHONATES; TARGET in [Vidilaseris, Keni; Goldman, Adrian] Univ Helsinki, Div Biochem, Dept Biosci, FI-00014 Helsinki, Finland; [Goldman, Adrian] Univ Leeds, Sch Biomed Sci, Leeds LS2 9JT, W Yorkshire, England; [Goldman, Adrian] Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England; [Johansson, Niklas G.; Turku, Ainoleena; Dreano, Loic; Perez, Daniel Ayuso; Zhang, Yuezhou; Tamminen, Matti; Grazhdankin, Evgeni; Kiriazis, Alexandros; af Gennas, Gustav Boije; Xhaard, Henri] Univ Helsinki, Drug Res Program, Div Pharmaceut Chem & Technol, Fac Pharm, FI-00014 Helsinki, Finland; [Khattab, Ayman; Meri, Seppo] Univ Helsinki, Malaria Res Lab, Translat Immunol Res Program, Dept Bacteriol & Immunol,Haartman Inst, FI-00014 Helsinki, Finland; [Wilkinson, Aaron; Fishwick, Colin W. G.] Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England in 2020.0, Cited 34.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

Membrane-bound pyrophosphatases (mPPases) regulate energy homeostasis in pathogenic protozoan parasites and lack human homologues, which makes them promising targets in e.g. malaria. Yet only few nonphosphorus inhibitors have been reported so far. Here, we explore an isoxazole fragment hit, leading to the discovery of small mPPase inhibitors with 6-10 mu M IC50 values in the Thermotoga maritima test system. Promisingly, the compounds retained activity against Plasmodium falciparum mPPase in membranes and inhibited parasite growth.

SDS of cas: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Johansson, NG; Turku, A; Vidilaseris, K; Dreano, L; Khattab, A; Perez, DA; Wilkinson, A; Zhang, YZ; Tamminen, M; Grazhdankin, E; Kiriazis, A; Fishwick, CWG; Meri, S; Yli-Kauhaluoma, J; Goldman, A; af Gennas, GB; Xhaard, H or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020 HIGH PERFORM POLYM published article about GAS-TRANSPORT PROPERTIES; POLYIMIDES; MEMBRANES; POLYMERS in [Zhang, Zi-Yang; Huang, Zhen-Zhong; Pan, Yang; Song, Cheng] Jiangxi Normal Univ, Key Lab Funct Small Organ Mol, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China in 2020, Cited 34. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

A new diamine bearing flexible ether, rigid pyridine, and bulky anthrone pendent group, 10,10-bis[4-(4-amino-2-pyridinoxy)phenyl]-9(10H)-anthrone (BAPPA), was prepared in three steps from anthrone. BAPPA was reacted with six conventional aromatic dianhydrides in N, N-dimethylacetamide (DMAc) to form the corresponding new poly(ether imide)s (PEIs) via the poly(ether amic acid) (PEAA) precursors with inherent viscosities ranging from 0.85 dL g(-1) to 1.26 dL g(-1) and thermal imidization. All the PEAAs could be cast from DMAc solution and thermally converted into transparent, flexible, and tough PEI films with tensile strength of 72.2-112.4 MPa, tensile modulus of 1.8-2.1 GPa, and elongation at break of 10-18%. These PEIs were predominantly amorphous and displayed excellent thermal stability with the glass transition temperature of 290-388 degrees C, the 5% weight loss temperature of 480-514 degrees C, and the residue of 68-43% at 800 degrees C in nitrogen. The PEIs derived from 1,4-bis(3,4-dicarboxyphenoxy)benzene dianhydride and 4,4 ‘-hexafluoroisopropylidenediphathalic anhydride exhibited excellent solubility in organic solvents such as N-methyl-2-pyrrolidinone, DMAc, N, N-dimethylformamide, pyridine, and even in tetrahydrofuran. Meanwhile, these PEIs also exhibited high optical transparency with the ultraviolet cutoff wavelength in the 374-427 nm range and the wavelength of 80% transparency in the range of 468-493 nm.

SDS of cas: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Zhang, ZY; Huang, ZZ; Pan, Y; Song, C or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. In 2020 MOLECULES published article about N-H INDOLES; ASYMMETRIC-SYNTHESIS; 3+2 CYCLOADDITION; ONE-POT; 3-NITROINDOLES; ACYLATION; 3-ACYLINDOLES; REARRANGEMENT; CONSTRUCTION; 3-AROYLINDOLES in [Tejedor, David; Diana-Rivero, Raquel; Garcia-Tellado, Fernando] Inst Prod Nat & Agrobiol, Consejo Super Invest Cient, Astroffs Francisco Sanchez 3, San Cristobal la Laguna 38206, Spain; [Diana-Rivero, Raquel] Univ La Laguna, Doctoral & Postgrad Sch, Apartado Postal 456, San Cristobal la Laguna 38200, Spain in 2020, Cited 84. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported. The protocol is based on the [3,3]-sigmatropic rearrangement of N-oxyenamines generated by the DABCO-catalyzed reaction of N-arylhydroxylamines and conjugated terminal alkynes, and delivers indoles endowed with a wide array of substitution patterns and topologies.

Recommanded Product: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 86-29-3. Wang, DF; Malmberg, R; Pernik, I; Prasad, SKK; Roemer, M; Venkatesan, K; Schmidt, TW; Keaveney, ST; Messerle, BA in [Wang, Danfeng; Malmberg, Robert; Pernik, Indrek; Roemer, Max; Venkatesan, Koushik; Keaveney, Sinead T.; Messerle, Barbara A.] Macquarie Univ, Dept Mol Sci, N Ryde, NSW 2109, Australia; [Prasad, Shyamal K. K.; Schmidt, Timothy W.] Univ New South Wales, ARC Ctr Excellence Exciton Sci, Sch Chem, Kensington, NSW 2052, Australia; [Pernik, Indrek; Roemer, Max; Messerle, Barbara A.] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia published Development of tethered dual catalysts: synergy between photo- and transition metal catalysts for enhanced catalysis in 2020, Cited 83. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

While dual photocatalysis-transition metal catalysis strategies are extensively reported, the majority of systems feature two separate catalysts, limiting the potential for synergistic interactions between the catalytic centres. In this work we synthesised a series of tethered dual catalysts allowing us to investigate this underexplored area of dual catalysis. In particular, Ir(i) or Ir(iii) complexes were tethered to a BODIPY photocatalyst through different tethering modes. Extensive characterisation, including transient absorption spectroscopy, cyclic voltammetry and X-ray absorption spectroscopy, suggest that there are synergistic interactions between the catalysts. The tethered dual catalysts were more effective at promoting photocatalytic oxidation and Ir-catalysed dihydroalkoxylation, relative to the un-tethered species, highlighting that increases in both photocatalysis and Ir catalysis can be achieved. The potential of these catalysts was further demonstrated through novel sequential reactivity, and through switchable reactivity that is controlled by external stimuli (heat or light).

Recommanded Product: 86-29-3. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Wang, DF; Malmberg, R; Pernik, I; Prasad, SKK; Roemer, M; Venkatesan, K; Schmidt, TW; Keaveney, ST; Messerle, BA or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about O-NITROSTYRENES; AROMATIC-AMINES; BOND; LIGAND; HYDROFORMYLATION; CARBONYLATION; COMPLEXES; CO; NITROBENZENE; MECHANISM, Saw an article supported by the National Key R&D Program of China [2018YFB1501600]; Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21773271, 21972151]. Published in SCIENCE PRESS in BEIJING ,Authors: Yang, L; Shi, LJ; Xia, CG; Li, FW. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. HPLC of Formula: C8H7NO3

An efficient route for the palladium-catalyzed reductive aminocarbonylation of olefins with nitroarenes was developed using carbon monoxide (CO) as both reductant and carbonyl source, which enables facile access to amides with excellent regioselectivity and broad substrate scope. It is found that the counter anions of the Pd catalyst precursors significantly affect the reaction chemoselectivity and amide regioselectivity. Branched amides were mainly obtained with K2PdCl4 as the metal catalyst, and phosphine ligands had no influence on the regioselectivity but affected the catalytic reactivity. However, phosphine ligands had significant effects on aminocarbonylation regioselectivity when Pd(CH3CN)(4)(OTf)(2) was used; monodentate phosphines tended to form branched amides, and bidentate phosphines mainly formed linear amides. Trapping experiments, primary kinetic studies, and control reactions with all possible N-species reduced from nitroarene indicated that the catalytic synthesis of branched and linear amides produced nitrene (further converted to enamide) and aniline, respectively, different from the previous ligand-controlled regioselective synthesis of amides via the aminocarbonylation of olefins with amines. Furthermore, the proposed synthesis route could be applied in the synthesis of gram-scale propanil under mild conditions. (C) 2020, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Yang, L; Shi, LJ; Xia, CG; Li, FW or concate me.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Selective Oxidation of Benzylic C-H Bonds Catalyzed by Cu(II)/{PMo12} WOS:000518875700021 published article about AEROBIC OXIDATION; EFFICIENT; POLYOXOMETALATE; HYDROCARBONS; TERT; OXYGENATION; ALKYLARENES; ACTIVATION; ETHYLBENZENE; COMPLEXES in [Li, Peihe; Wang, Yingying; Wang, Xia; Wang, Yin; Liu, Ying; Hu, Jing; Duan, Limei; Liu, Jinghai] Inner Mongolia Univ Nationalities, Coll Chem & Mat Sci, NII, Inner Mongolia Key Lab Carbon Nanomat, Tongliao 028000, Peoples R China; [Hu, Changwen] Beijing Inst Technol, Sch Chem & Chem Engn, Beijing Key Lab Photoelect Electrophoton, Minist Educ,Key Lab Cluster Sci, Beijing 100081, Peoples R China; [Huang, Keke] Jilin Univ, Coll Chem, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Peoples R China in 2020.0, Cited 73.0. HPLC of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Precise catalytic regulation of carbon radical generation by a highly active oxygen radical to abstract the H atom in a C-H bond is an effective method for the selective activation of C-H synthetic chemistry. Herein, we report a facile catalyst system with commercially available copper(II)/{PMo12} to form a tert-butanol radical intermediate for the selective oxidation of benzylic C-H bonds. The reaction shows a broad range of substrates (benzyl methylene, benzyl alcohols) with good functional group tolerance and chemical selectivity. The corresponding carbonyl compounds were synthesized with good yields under mild conditions. DFT calculations and experimental analysis further demonstrated a reasonable carbon radical mechanism for this type of organic transformation reaction.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, PH; Wang, YY; Wang, X; Wang, Y; Liu, Y; Huang, KK; Hu, J; Duan, LM; Hu, CW; Liu, JH or concate me.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. In 2020.0 J POLYM RES published article about HIGH ORGANOSOLUBILITY; PRETILT ANGLE; DIAMINE in [Yuan, Chengyun; Wang, Yinghan] Sichuan Univ, Coll Polymer Sci & Engn, State Key Lab Polymer Mat Engn, Chengdu 610065, Peoples R China; [Sun, Zhen] Shanghai KaiYuLin Pharmaceut Technol Co LTD, Shanghai 201805, Peoples R China in 2020.0, Cited 24.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Four triphenylpyridine diamines with different substituent structure were successfully synthesized and polymerized to obtained polyimides (PIs) via one-step. The diamines and PIs were characterized by FTIR and H-1-NMR spectra. The aggregated structure of PIs was amorphous by wide angle X-ray diffraction test. The structure of the substituent had an important influence on the properties of PI (such as solubility, thermal stability, optical and mechanical properties). The introduction of tert-butyl group could reduce the solubility in non-polar solvent of PI. In addition, the introduction of hydroxyl group alone could increase the solubility in polar solvent of polymer due to the large polarity of the hydroxyl groups. All PIs exhibited high thermal stability and heat resistance, but the introduction of too much tert-butyl group reduced the thermal stability of PI. The introduction of tert-butyl group could effectively improve the optical properties of PIs. The maximum transmittance of PIs was above 85% (87.2-90.3%).

Welcome to talk about 100-19-6, If you have any questions, you can contact Yuan, CY; Sun, Z; Wang, YH or send Email.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 100-19-6. In 2019.0 EUR J ORG CHEM published article about C-H BONDS; INTERMOLECULAR AMIDATION; REGIOSPECIFIC SYNTHESIS; OXIME ETHER; NITROARENES; CYCLIZATION; ARENES; 1H-INDAZOLES; AZOBENZENES; ACTIVATION in [Liu, Lingling; Wang, Ning; Dai, Chenyang; Han, Yi; Yang, Shan; Huang, Zhibin; Zhao, Yingsheng] Soochow Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, 199 Renai St, Suzhou 215123, Jiangsu, Peoples R China in 2019.0, Cited 54.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A method to achieve rhodium(III)-catalyzed, potassium acetate enabled intermolecular C-H amination of ketoximes using various benzenesulfonamide, especially 4-nitrobenzenesulfonamide is reported. Various aryl ketoximes substituted with electron-withdrawing functional groups were all well tolerated and produced the corresponding products in moderate to good yields. A preliminary mechanistic study revealed that potassium acetate is essential to realizing intermolecular amination.

Product Details of 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Metal-Free Cross-Dehydrogenative C-O Coupling of Carbonyl Compounds with N-Hydroxyimides: Unexpected Selective Behavior of Highly Reactive Free Radicals at an Elevated Temperature WOS:000516665800016 published article about BOND FORMATION; HYDROXYPHTHALIMIDE SYNTHESIS; AMINO-ACIDS; ALDEHYDES; FUNCTIONALIZATION; ESTERIFICATION; DERIVATIVES; EFFICIENT; OLIGOMERIZATION; DIMERIZATION in [Krylov, Igor B.; Lopat’eva, Elena R.; Budnikov, Alexander S.; Nikishin, Gennady I.; Terent’ev, Alexander O.] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia; [Lopat’eva, Elena R.; Budnikov, Alexander S.] Mendeleev Univ Chem Technol Russia, 9 Miusskaya Sq, Moscow 125047, Russia in 2020, Cited 68. SDS of cas: 86-29-3. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

Cross-dehydrogenative C-O coupling of N-hydroxyimides with ketones, esters, and carboxylic acids was achieved employing the di-tertbutyl peroxide as a source of free radicals and a dehydrogenating agent. The proposed method is experimentally simple and demonstrates the outstanding efficiency for the challenging CH substrates, such as unactivated esters and carboxylic acids. It was shown that N-hydroxyphthalimide drastically affects the oxidative properties of t-BuOOt-Bu by intercepting the t-BuO center dot radicals with the formation of phthalimide-N-oxyl radicals, a species responsible for both hydrogen atom abstraction from the CH reagent and the selective formation of the C-O coupling product by selective radical cross-recombination. The practical applicability of the developed method was exemplified by the single-stage synthesis of commercial reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-hydroxysuccinimide, whereas in the standard synthetic approach, four stages are necessary.

SDS of cas: 86-29-3. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Liu, XT; Zhang, LK; Wang, JM; Shang, NZ; Gao, ST; Wang, C; Gao, YJ in WILEY published article about AMMONIA-BORANE; REDUCTIVE AMINATION; GRAPHENE OXIDE; NANOPARTICLES; EFFICIENT; DEHYDROGENATION in [Liu, Xiaotong; Zhang, Longkang; Wang, Junmin; Shang, Ningzhao; Gao, Shutao; Wang, Chun] Hebei Agr Univ, Coll Sci, Baoding 071001, Hebei, Peoples R China; [Gao, Yongjun] Hebei Univ, Coll Chem & Environm Sci, Baoding 071002, Peoples R China in 2020.0, Cited 35.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The non-precious metal catalysts with high catalytic activity is extremely desirable but still full of challenges. In this paper, CoCu bimetal immobilized on nitrogen-doped porous carbon (CoCu-N-C) was prepared by an effective ligand-stabilized pyrolysis strategy. CoCu-N-C exhibited excellent catalytic efficiency for the transfer hydrogenation of nitroarenes with ammonia borane as hydrogen source, which can be ascribed to the well dispersed metal nanoparticles, the synergetic interaction of CoCu bimetal and nitrogen-doped carbon. The durability and recyclability experiments of the recycled CoCu-N-C catalyst indicated that no obvious change in catalytic performance was observed after five consecutive cycles. To gain insight into the catalytic mechanism of CoCu-N-C for the hydrogenation reaction, density functional theory calculations was also conducted. This work provides an universal approach for constructing highly efficient non-precious metal heterogeneous catalysts and which may find diverse high performance applications.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Liu, XT; Zhang, LK; Wang, JM; Shang, NZ; Gao, ST; Wang, C; Gao, YJ or concate me.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem