Tag: M.W=150-200

An article Efficient asymmetric synthesis of chiral alcohols using high 2-propanol tolerance alcohol dehydrogenase SmADH2 via an environmentally friendly TBCR system WOS:000505550900027 published article about CARBONYL REDUCTASE; KETONE REDUCTION; LEIFSONIA; BIOCATALYSIS; MECHANISM; ENZYMES; CHAIN in [Yang, Zeyu; Fu, Hengwei; Ye, Wenjie; Xie, Youyu; Liu, Qinghai; Wang, Hualei; Wei, Dongzhi] East China Univ Sci & Technol, New World Inst Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China in 2020.0, Cited 34.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

Alcohol dehydrogenases (ADHs) together with the economical substrate-coupled cofactor regeneration system play a pivotal role in the asymmetric synthesis of chiral alcohols; however, severe challenges concerning the poor tolerance of enzymes to 2-propanol and the adverse effects of the by-product, acetone, limit its applications, causing this strategy to lapse. Herein, a novel ADH gene smadh2 was identified from Stenotrophomonas maltophilia by traditional genome mining technology. The gene was cloned into Escherichia coli cells and then expressed to yield SmADH2. SmADH2 has a broad substrate spectrum and exhibits excellent tolerance and superb activity to 2-propanol even at 10.5 M (80%, v/v) concentration. Moreover, a new thermostatic bubble column reactor (TBCR) system is successfully designed to alleviate the inhibition of the by-product acetone by gas flow and continuously supplement 2-propanol. The organic waste can be simultaneously recovered for the purpose of green synthesis. In the sustainable system, structurally diverse chiral alcohols are synthesised at a high substrate loading (>150 g L-1) without adding external coenzymes. Among these, about 780 g L-1 (6 M) ethyl acetoacetate is completely converted into ethyl (R)-3-hydroxybutyrate in only 2.5 h with 99.9% ee and 7488 g L-1 d(-1) space-time yield. Molecular dynamics simulation results shed light on the high catalytic activity toward the substrate. Therefore, the high 2-propanol tolerance SmADH2 with the TBCR system proves to be a potent biocatalytic strategy for the synthesis of chiral alcohols on an industrial scale.

Welcome to talk about 100-19-6, If you have any questions, you can contact Yang, ZY; Fu, HW; Ye, WJ; Xie, YY; Liu, QH; Wang, HL; Wei, DZ or send Email.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Chen, ZL; Hu, FL; Huang, SL; Zhao, ZX; Mao, H; Qin, WL in AMER CHEMICAL SOC published article about ONE-POT SYNTHESIS; ASYMMETRIC-SYNTHESIS; DERIVATIVES; WATER; ORGANOSELENIUM; DISELENIDES; SULFONES; KETONES; ACID in [Chen, Zhili; Hu, Fangli; Huang, Shengli; Zhao, Zhengxing; Qin, Wenling] Chongqing Univ, Chongqing Key Lab Nat Prod Synth & Drug Res, Sch Pharmaceut Sci, Chongqing 401331, Peoples R China; [Huang, Shengli] Chongqing Univ, Sch Chem & Chem Engn, Chongqing 401331, Peoples R China; [Mao, Hui] Jinhua Polytech, Pharmaceut & Mat Engn Sch, Jinhua 321000, Zhejiang, Peoples R China in 2019.0, Cited 43.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Organocatalytic selenosulfonylation of the C-C double bond of alpha,beta-unsaturated ketones to construct two contiguous stereogenic centers in an aqueous medium was described. A series of alpha-selenyl and beta-sulfonyl ketones with various functional groups were synthesized in good yields and enantioselectivities with saturated NaCl solution as the solvent. In addition, this protocol had been successfully scaled up to a decagram scale via a simple workup procedure.

Welcome to talk about 100-19-6, If you have any questions, you can contact Chen, ZL; Hu, FL; Huang, SL; Zhao, ZX; Mao, H; Qin, WL or send Email.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2021 RSC ADV published article about ONE-POT SYNTHESIS; ARYL HALIDES; ARYLATION; CHEMISTRY; COMPLEX; PERSPECTIVE; AMIDATION; EFFICIENT; REAGENTS; SYSTEM in [Sallio, Romain; Pakulski, Pawel; Diachenko, Iryna; Berteina-Raboin, Sabine; Colas, Cyril; Gillaizeau, Isabelle] Univ Orleans, Inst Organ & Analyt Chem, ICOA UMR 7311 CNRS, Rue Chartres, F-45100 Orleans, France; [Payard, Pierre-Adrien; Fabre, Indira; Grimaud, Laurence] PSL Univ, Sorbonne Univ, Dept Chim,CNRS, Lab Biomol,LBM,Ecole Normale Super, F-75005 Paris, France; [Ciofini, Ilaria] PSL Univ, Inst Chem Hlth & Life Sci, CNRS, Chim ParisTech,I CLeHS, F-75005 Paris, France in 2021, Cited 38. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Recommanded Product: 2,2-Diphenylacetonitrile

This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N-arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance.

Recommanded Product: 2,2-Diphenylacetonitrile. Welcome to talk about 86-29-3, If you have any questions, you can contact Sallio, R; Payard, PA; Pakulski, P; Diachenko, I; Fabre, I; Berteina-Raboin, S; Colas, C; Ciofini, I; Grimaud, L; Gillaizeau, I or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019 JAMBA-J DISASTER RIS published article about CYANOBACTERIA; BIODETERIORATION; ENZYMES; COPPER; LIGHT in [Munyai, Thabelo R.; Sonqishe, Thantaswa] Univ Venda, Dept Ecol & Resource Management, Thohoyandou, South Africa; [Gumbo, Jabulani R.] Univ Venda, Dept Hydrol & Water Resource Management, Thohoyandou, South Africa in 2019, Cited 33. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Product Details of 86-29-3

A brick pavement, tramped by humans, is exposed to atmospheric elements, thus allowing cyanobacteria and algae to colonise. In this article, we report on the factors that contribute to the slipperiness of a brick pavement at the University of Venda in the Limpopo province of the South Africa. Samples were collected from brick surfaces either colonised by green algae (treated) or not (control). The samples were acid-digested and analysed for metals by Inductively Coupled Plasma Mass Spectrometry (ICP MS) in parts per billion (ppb). The treated bricks, with green algae, had average high metal contents (ppb): Al 9456.02, Ti 731.23, V 46.44, Cr 78.85, Mn 862.93, Fe 16295.18, Co 23.57, Ni 59.36, Cu 66.31, Zn 160.57, As 7.92, Se 10.45, Mo 6.74, Cd 5.19, Sn 4.65, Sb 2.31 and Pb 19.51. In contrast, control bricks had a low average of metal content (ppb) as follows: Al 2.99, Ti 0.28, V 4.04, Cr 1.42, Mn 4.29, Fe 20.89, Co 0.36, Ni 2.74, Cu 5.64, Zn 4.21, As 0.56, Se <3.00, Mo 0.88, Cd 0.01, Sn 1.05, Sb 0.04 and Pb 0.04. Other factors that promote algae colonisation include high solar radiation, neutral pH, nutrients, low electrical conductivity and total dissolved solids. The algae colonisation of brick pavement results in an unaesthetic sighting and a slippery surface that is hazardous to humans. Product Details of 86-29-3. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Antiproliferative effects of chalcones on T cell acute lymphoblastic leukemia-derived cells: Role of PKC beta WOS:000531534200001 published article about PROTEIN-KINASE-C; IN-VITRO; CANCER; DERIVATIVES; INHIBITORS; RECEPTOR; COMPLEX; MODEL in [Corsini, Emanuela; Esposito, Sara] Univ Milan, Lab Toxicol, Dipartimento Sci Polit & Ambientali, Milan, Italy; [Facchetti, Giorgio; Rimoldi, Isabella; Christodoulou, Michael S.] Univ Milan, DISFARM, Sez Chim Gen & Organ A Marchesini, Via Venezian 21, I-20133 Milan, Italy; [Maddalon, Ambra] Univ Milan, Lab Toxicol, Dipartimento Sci Farmacol & Biomol, Milan, Italy in 2020.0, Cited 38.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Safety of 1-(4-Nitrophenyl)ethanone

In this study, a series of 20 chalcone derivatives was synthesized, and their antiproliferative activity was tested against the human T cell acute lymphoblastic leukemia-derived cell line, CCRF-CEM. On the basis of the structural features of the most active compounds, a new library of chalcone derivatives, according to the structure-activity relationship design, was synthesized, and their antiproliferative activity was tested against the same cancer cell line. Furthermore, four of these derivatives (compounds 3, 4, 8, 28), based on lower IC50 values (between 6.1 and 8.9 mu M), were selected for further investigation regarding the modulation of the protein expression of RACK1 (receptor for activated C kinase), protein kinase C (PKC)alpha and PKC beta, and their action on the cell cycle level. The cell cycle analysis indicated a block in the G0/G1 phase for all four compounds, with a statistically significant decrease in the percentage of cells in the S phase, with no indication of apoptosis (sub-G0/G1 phase). Compounds 4 and 8 showed a statistically significant reduction in the expression of PKC alpha and an increase in PKC beta, which together with the demonstration of an antiproliferative role of PKC beta, as assessed by treating cells with a selective PKC beta activator, indicated that the observed antiproliferative effect is likely to be mediated through PKC beta induction.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Corsini, E; Facchetti, G; Esposito, S; Maddalon, A; Rimoldi, I; Christodoulou, MS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 2,2-Diphenylacetonitrile. Krylov, IB; Lopat’eva, ER; Budnikov, AS; Nikishin, GI; Terent’ev, AO in [Krylov, Igor B.; Lopat’eva, Elena R.; Budnikov, Alexander S.; Nikishin, Gennady I.; Terent’ev, Alexander O.] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia; [Lopat’eva, Elena R.; Budnikov, Alexander S.] Mendeleev Univ Chem Technol Russia, 9 Miusskaya Sq, Moscow 125047, Russia published Metal-Free Cross-Dehydrogenative C-O Coupling of Carbonyl Compounds with N-Hydroxyimides: Unexpected Selective Behavior of Highly Reactive Free Radicals at an Elevated Temperature in 2020, Cited 68. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

Cross-dehydrogenative C-O coupling of N-hydroxyimides with ketones, esters, and carboxylic acids was achieved employing the di-tertbutyl peroxide as a source of free radicals and a dehydrogenating agent. The proposed method is experimentally simple and demonstrates the outstanding efficiency for the challenging CH substrates, such as unactivated esters and carboxylic acids. It was shown that N-hydroxyphthalimide drastically affects the oxidative properties of t-BuOOt-Bu by intercepting the t-BuO center dot radicals with the formation of phthalimide-N-oxyl radicals, a species responsible for both hydrogen atom abstraction from the CH reagent and the selective formation of the C-O coupling product by selective radical cross-recombination. The practical applicability of the developed method was exemplified by the single-stage synthesis of commercial reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-hydroxysuccinimide, whereas in the standard synthetic approach, four stages are necessary.

Welcome to talk about 86-29-3, If you have any questions, you can contact Krylov, IB; Lopat’eva, ER; Budnikov, AS; Nikishin, GI; Terent’ev, AO or send Email.. Safety of 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2021.0 CHINESE J CHEM published article about OPPENAUER-TYPE OXIDATION; AEROBIC OXIDATION; ALCOHOL OXIDATION; AQUEOUS-MEDIA; SELECTIVE OXIDATION; HYDROGEN-PRODUCTION; METAL-FREE; CATALYST; IRIDIUM; KETONES in [Hao, Zhiqiang; Liu, Kang; Feng, Qi; Dong, Qing; Han, Zhangang; Lin, Jin] Hebei Normal Univ, Hebei Key Lab Organ Funct Mol, Coll Chem & Mat Sci, Shijiazhuang 050024, Hebei, Peoples R China; [Ma, Dongzhu] Hebei Coll Ind & Technol, Dept Environm & Chem Engn, Shijiazhuang 050091, Hebei, Peoples R China; [Lu, Guo-Liang] Univ Auckland, Auckland Canc Soc Res Ctr, Fac Med & Hlth Sci, Private Bag 92019, Auckland 1142, New Zealand in 2021.0, Cited 97.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

Main observation and conclusion Four ruthenium(II) complexes 1-4 [RN=CH-(2,4-(Bu-t)(2)C6H2O)]RuH(PPh3)(2)(CO) (R = C6H5, 1; R = 4-MeC6H4, 2; R = 4-ClC6H4, 3; R = 4-BrC6H4, 4) bearing Schiff base ligands were prepared by treating RuHClCO(PPh3)(3) with RN=CH-(2,4-(Bu-t)(2)C6H2OH (L1-L4) in the presence of triethylamine. Their structures were fully characterized by elemental analysis, IR, NMR spectroscopy and X-ray crystallography. These Ru(II) complexes exhibit high catalytic performance and good functional-group compatibility in the acceptorless dehydrogenation of secondary alcohols, affording the corresponding ketones in 82%-94% yields.

Welcome to talk about 100-19-6, If you have any questions, you can contact Hao, ZQ; Liu, K; Feng, Q; Dong, Q; Ma, DZ; Han, ZG; Lu, GL; Lin, J or send Email.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 CATAL COMMUN published article about ASYMMETRIC TRANSFER HYDROGENATION; KETONES; REDUCTION in [Wang, Yangyang; Du, Zhengyin] Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Gansu, Peoples R China; [Wang, Yangyang; Zheng, Tingting; Sun, Hongjian; Li, Xiaoyan] Shandong Univ, Minist Educ, Key Lab Special Funct Aggregated Mat, Sch Chem & Chem Engn, Shanda Nanlu 27, Jinan 250100, Shandong, Peoples R China; [Zheng, Tingting] Capital Normal Univ, Dept Chem, Beijing 100037, Peoples R China in 2019.0, Cited 19.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

Selenophenolato hydrido iron(II) complexes 1-3 cis-[(H)(SeAr)Fe(PMe3)(4)] (Ar = C6H5 (1), p-MeOC6H4 (2) and o-MeC6H4 (3)) could catalyze transfer hydrogenation of aldehydes and ketones. Among the three complexes, catalyst 1 exhibited the highest catalytic activity. The catalytic reactions took place under very mild conditions, using isopropanol as solvent and hydrogen source, (BuONa)-Bu-t as base under 60-80 degrees C. This catalytic system has good tolerance for many functional groups, such as halides, C=C double bonds, nitro groups and cyano groups at the phenyl ring of the substrates.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2021.0 J BRAZIL CHEM SOC published article about CHEMICAL-SHIFTS; CONFORMATIONAL-ANALYSIS; NATURAL-PRODUCTS; NMR; H-1; PREDICTION; AGENTS in [Souza Jr., Joselito S.; Souza, Helivaldo D. S.; Oliveira, Rafael F. de; Alves, Francinara S.; Trindade, Emmely O.; Lira, Bruno F.; Rocha, Gerd B.; Athayde-Filho, Petronio F. de] Univ Fed Paraiba, Dept Quim, BR-58051900 Joao Pessoa, PB, Brazil; [Martins, Evandro P. S.] Univ Estadual Piaui, Dept Quim, BR-64260000 Piripiri, PI, Brazil; [Lima, Edeltrudes O.; Cordeiro, Laisa V.; Barbosa-Filho, Jose M.] Univ Fed Paraiba, Dept Ciencias Farmaceut, BR-58051900 Joao Pessoa, PB, Brazil in 2021.0, Cited 45.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

Four new piperine derivatives, PC1-PC4, were synthesized, and their structures were fully characterized by infrared (IR) and H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopies. Quantum chemical calculations were performed using density functional theory (DFT) with the B3LYP-D3/6-31G(d,p) and 6-311+G(2d,p) basis sets. Electronic properties, such as the energy gap between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) and some global chemical reactivity descriptors, were evaluated to study the reactivity and stability of the compounds. H-1 and C-13 NMR chemical shifts were calculated by using the gauge-invariant atomic orbital (GIAO) method and compared with experimental values. In addition, the compounds were evaluated in an antifungal study against Candida, Trichophyton and Microsporum strains, and only PC4 showed 70% inhibition in ten tested strains, with a minimum inhibitory concentration (MIC) ranging from 1.23-2.46 mu mol mL(-1) and a minimum fungicide concentration (MFC) ranging from 9.84-19.68 mu mol mL(-1), and presented a fungistatic effect.

SDS of cas: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about AGGREGATION-INDUCED EMISSION; PYRROLE-DERIVED ALKALOIDS; INDUCED ENHANCED-EMISSION; SUBSTITUTED PYRROLES; REAL-TIME; CONSTRUCTION; QUINOLINE; COMPOUND; AMINE, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21871226, 21572194]; Science and Technology Planning Project of Hunan Province [2019RS2039]; Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, Guangzhou, China (South China University of Technology) [2019B030301003]. Quality Control of 1-(4-Nitrophenyl)ethanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Chang, D; Chen, JJ; Liu, Y; Huang, HW; Qin, AJ; Deng, GJ. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal- free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.

Quality Control of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Chang, D; Chen, JJ; Liu, Y; Huang, HW; Qin, AJ; Deng, GJ or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem