Tag: M.W=150-200

Recently I am researching about BOND-FORMING REACTIONS; TITANIUM COMPLEXES; IMIDO METALLOCENE; CRYSTAL-STRUCTURE; REACTIVITY; CHEMISTRY; ACTIVATION; PHOSPHORUS; RUTHENIUM; PHOSPHIDO, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21871029, 21672024]; Deutsche Forschungsgemeinschaft (DFG) through the Heisenberg programGerman Research Foundation (DFG) [WA 2513/6, WA 2513/8]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Wang, DQ; Wang, SC; Hou, GH; Zi, GF; Walter, MD. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile. COA of Formula: C14H11N

A Lewis base supported terminal uranium phosphinidene, [eta(5)-1,3-(Me3C)(2)C5H3]2U(= P-2,4,6-(Bu3C6H2)-Bu-t)(OPMe3) (5), is isolated from the reaction of the uranium methyl chloride [eta(5)- 1,3-(Me3C)(2)C5H3](2)U(Cl) Me (4) with 2, 4, 6-(Me3C)(3)C6H2PHK in toluene in the presence of Me3PO. Moreover, the reactivity of uranium phospinidene 5 toward a series of small molecules was comprehensively explored. While no reactivity of 5 with internal alkynes is observed attributed to steric hindrance, it readily reacts in good yields with various small molecules including isothiocyanates, aldehydes, imines, diazenes, carbodiimides, nitriles, isonitriles, and organic azides, yielding uranium sulfidos, oxidos, metallaheterocycles, and imido complexes.

COA of Formula: C14H11N. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. In 2020.0 J HETEROCYCLIC CHEM published article about ALZHEIMERS-DISEASE; BIOLOGICAL EVALUATION; DESIGN; CHALCONES; DRUG in [Mekky, Ahmed E. M.; Sanad, Sherif M. H.] Cairo Univ, Fac Sci, Chem Dept, Giza 12613, Egypt in 2020.0, Cited 56.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The appropriate pyridine-2(1H)-thiones were reacted with an equivalent amount of 5-(chloromethyl)-2-hydroxybenzaldehyde in ethanol in the presence of potassium hydroxide to give the corresponding 2-hydroxybenzaldehyde derivatives in excellent yields. The latter derivatives were taken as key synthons for the preparation of the target hybrids. Therefore, 2-hydroxybenzaldehydes were reacted with benzoylglycine in acetic anhydride in the presence of fused sodium acetate at 100 degrees C for 6 hours to afford a new series of nicotinonitrile-coumarin hybrids. The in vitro acetylcholinesterase inhibitory activities were estimated for the new coumarins. The results were expressed as the inhibition percentage of the tested hybrids at concentration of 25 nM, compared to donepezil as a reference (inhibition percentage of 70.5). Coumarin hybrids linked to 6-(4-nitrophenyl) or 6-(4-chlorophenyl)-4-phenylnicotinonitrile exhibited more effective inhibitory activities than donepezil with inhibition percentages of 94.1 and 72.3, respectively. The new coumarins were tested for their free radical-scavenging capabilities against DPPH. Furthermore, some new coumarins were tested for in vitro cytotoxic activity against each MCF-10A, MCF-7, Caco2, and HEPG2. The new hybrids showed cytotoxicity in micromolar range (IC(50)of 3.5-13.9 mu M) against all tested cell lines. These results clearly demonstrated that the hybrids being tested are not cytotoxic at the concentration required to inhibit acetylcholinesterase effectively.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Mekky, AEM; Sanad, SMH or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. In 2019.0 ANGEW CHEM INT EDIT published article about ENANTIOSELECTIVE REDUCTION; HYDRIDE COMPLEXES; REACTIVITY; KETONES; DESYMMETRIZATION; BORANE; MECHANISM; ALDEHYDES; DIBORANE; REAGENTS in [Falconnet, Alban; Magre, Marc; Rueping, Magnus] Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany; [Maity, Bholanath; Cavallo, Luigi; Rueping, Magnus] King Abdullah Univ Sci & Technol, KAUST Catalysis Ctr, Thuwal 239556900, Saudi Arabia in 2019.0, Cited 64.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Asymmetric catalysis with readily available, cheap, and non-toxic alkaline earth metal catalysts represents a sustainable alternative to conventional synthesis methodologies. In this context, we describe the development of a first Mg-II-catalyzed enantioselective hydroboration providing the products with excellent yields and enantioselectivities. NMR spectroscopy studies and DFT calculations provide insights into the reaction mechanism and the origin of the enantioselectivity which can be explained by a metal-ligand cooperative catalysis pathway involving a non-innocent ligand.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Falconnet, A; Magre, M; Maity, B; Cavallo, L; Rueping, M or concate me.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020.0 INT J BIOL MACROMOL published article about SHELL HOLLOW SPHERES; HETEROGENEOUS CATALYST; SELECTIVE HYDROGENATION; COUPLING REACTIONS; CARBON DOT; NANOPARTICLES; HALLOYSITE; COPPER; OXIDE; REDUCTION in [Esmaeilzadeh, Mahsa; Salehi, Zeinab] Univ Tehran, Coll Engn, Sch Chem Engn, Tehran, Iran; [Sadjadi, Samahe] Iran Polymer & Petrochem Inst, Fac Petrochem, Gas Convers Dept, Tehran, Iran in 2020.0, Cited 60.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Computed Properties of C8H7NO3

Magnetic graphene quantum dots were prepared and incorporated in cyclodextrin decorated chitosan. The resulting hybrid was then palladated and characterized using TEM, BET, TGA, XRD, VSM, ICP and FTIR spectroscopy. Next, the catalytic activity of the prepared hybrid catalyst that benefits from the chemistry of both carbohydrates and magnetic graphene quantum dots was investigated for promoting hydrogenation reaction of nitroarenes in aqueous media under mild reaction condition. The study of the catalyst performance confirmed high catalytic activity and selectivity of the catalyst towards hydrogenation of the nitro group. Moreover, the catalyst could be magnetic-ally separated from the reaction mixture and recycled up to ten reaction runs with a slight loss of the catalytic activity and Pd leaching.These results showed that the hybrid of magnetic graphene quantum dots and carbohydrates is an efficient catalyst support that can be potentially applied for the immobilization of nanoparticles to furnish heterogeneous catalysts for promoting the chemical transformations. (C) 2020 Elsevier B.V. All rights reserved.

Welcome to talk about 100-19-6, If you have any questions, you can contact Esmaeilzadeh, M; Sadjadi, S; Salehi, Z or send Email.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article I-2-promoted tandem cyclization to synthesize polysubstituted pyrano [3,2-c]chromene-2,5-diones WOS:000502887400004 published article about DOMINO PROCESS; EFFICIENT; 4-HYDROXYCOUMARINS in [Cai, Qun; Yang, Mian; Peng, Na; Liu, Yi] Wuhan Univ Sci & Technol, Sch Chem & Chem Engn, Coal Convers & New Carbon Mat Key Lab Hubei Prov, Wuhan 430081, Hubei, Peoples R China; [Zhuang, Shiyi; Wu, Anxin] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Hubei, Peoples R China; [Liu, Yi] Wuhan Univ, Coll Chem & Mol Sci, State Key Lab Virol, Wuhan 430072, Hubei, Peoples R China; [Liu, Yi] Wuhan Univ, Coll Chem & Mol Sci, Key Lab Analyt Chem Biol & Med MOE, Wuhan 430072, Hubei, Peoples R China in 2019.0, Cited 28.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

An efficient and convenient method for the synthesis of various substituted pyrano[3,2-c]chromene-2,5-diones was developed via the I-2-promoted tandem cyclization of commercially available aryl methyl ketones and 4-hydroxycoumarins. Preliminary mechanism studies indicated that the reaction involved a consecutive iodination/Kornblum oxidation/annulation process. HI produced in the I-2-DMSO system acted as an important promoter, accelerating the annulation protocol. (C) 2019 Elsevier Ltd. All rights reserved.

Computed Properties of C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 ANGEW CHEM INT EDIT published article about ASYMMETRIC TRANSFER HYDROGENATION; VERSATILE COORDINATION; PINCER COMPLEXES; BOND ACTIVATION; NITRILES; KETONES; CARBENE; CO2; DIHYDROGEN; CHEMISTRY in [Buhaibeh, Ruqaya; Bruneau-Voisine, Antoine; Willot, Jeremy; Duhayon, Carine; Valyaev, Dmitry A.; Lugan, Noel; Canac, Yves; Sortais, Jean-Baptiste] Univ Toulouse, CNRS, UPS, LCC CNRS, 205 Route Narbonne, F-31077 Toulouse 4, France; [Filippov, Oleg A.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds INEOS, 28 Vavilov Str,GSP-1,B-334, Moscow 119991, Russia; [Bruneau-Voisine, Antoine] Univ Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, France; [Sortais, Jean-Baptiste] Inst Univ France, 1 Rue Descartes, F-75231 Paris 05, France in 2019.0, Cited 72.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Safety of 1-(4-Nitrophenyl)ethanone

Deprotonation of the Mn-I NHC-phosphine complex fac-[MnBr(CO)(3)(k(2)P,C-Ph2PCH2NHC)] (2) under a H-2 atmosphere readily gives the hydride fac-[MnH(CO)(3)(k(2)P,C-Ph2PCH2NHC)] (3) via the intermediacy of the highly reactive 18-e NHC-phosphinomethanide complex fac-[Mn-(CO)(3)(k(3)P,C,C-Ph2PCHNHC)] (6a). DFT calculations revealed that the preferred reaction mechanism involves the unsaturated 16-e mangana-substituted phosphonium ylide complex fac-[Mn(CO)(3)(k(2)P,C-Ph2P=CHNHC)] (6b) as key intermediate able to activate H-2 via a non-classical mode of metal-ligand cooperation implying a formal lambda(5)-P-lambda(3)-P phosphorus valence change. Complex 2 is shown to be one of the most efficient pre-catalysts for ketone hydrogenation in the Mn-I series reported to date (TON up to 6200).

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Buhaibeh, R; Filippov, OA; Bruneau-Voisine, A; Willot, J; Duhayon, C; Valyaev, DA; Lugan, N; Canac, Y; Sortais, JB or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 ORG LETT published article about NUCLEAR-MAGNETIC-RESONANCE; SYN-ANTI ISOMERIZATION; OXIME ETHERS; PHOTOISOMERIZATION; MECHANISM; ESTERS; SHIFT; MILD in [Ball-Jones, Matthew P.; Tyler, Jasper; Mora-Rado, Helena; Harrity, Joseph P. A.] Univ Sheffield, Dept Chem, Brook Hill, Sheffield S3 7HF, S Yorkshire, England; [Mora-Rado, Helena; Czechtizky, Werngard; Mendez, Maria] Sanofi Aventis Deutschland GmbH, R&D, Ind Pk Hochst G838, D-65926 Frankfurt, Germany; [Czechtizky, Werngard] AstraZeneca, Resp Inflammat Autoimmun IMED Biotech Unit, S-43186 Gothenburg, Sweden in 2019.0, Cited 28.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

The greater geometric lability of hydrazones compared to that of oxime ethers is used as a basis to overcome the reluctance of Z-oxime ether azatrienes to undergo electrocyclization toward the synthesis of borylated (heteroaromatic) pyridines and ring-fused analogues. Such hydrazones now allow access to previously inaccessible tri- and tetrasubstituted 3-borylpyridines in high yields.

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Ball-Jones, MP; Tyler, J; Mora-Rado, H; Czechtizky, W; Mendez, M; Harrity, JPA or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Experimental and Computational Insights into the Water-Mediated Decomposition of N-Sulfonylhydrazones: A Catalyst-Free Synthesis of gamma-Keto/Nitrile Sulfones WOS:000510016500001 published article about METAL-FREE CYCLOPROPANATION; CROSS-COUPLING REACTIONS; CONJUGATE ADDITION; CASCADE REACTIONS; MICHAEL ADDITION; DIAZO-COMPOUNDS; TOSYLHYDRAZONES; EFFICIENT; NITRILES; CARBENE in [Goyal, Shagun; Budhiraja, Meenakshi; Mandal, Debasish; Tyagi, Vikas] Thapar Inst Engn & Technol, Sch Chem & Biochem, Patiala 147004, Punjab, India in 2020.0, Cited 67.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

This work is an example of water-mediated decomposition of N-sulfonylhydrazones used as sulfonyl-transferring reagents in the selective sulfa-Michael reaction in the absence of any base or catalyst. A wide range of substituted N-sulfonylhydrazones were tested as sources of sulfonyl anions with enones or acrylonitrile, which in turn provided the gamma- keto/nitrile sulfones in very good yields. Additionally, we have performed a rigorous computational mechanistic study to investigate the role of water which demonstrates the key role of water in the hydrogen abstraction from N-tosylhydrazone to initiate the reaction.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Goyal, S; Budhiraja, M; Mandal, D; Tyagi, V or concate me.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about BIOLOGICAL EVALUATION; MOLECULAR DOCKING; DERIVATIVES; DESIGN; HYDRAZIDES; DISCOVERY; SAR, Saw an article supported by the . Name: 1-(4-Nitrophenyl)ethanone. Published in SPRINGER in NEW YORK ,Authors: Sanad, SMH; Mekky, AEM. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

The starting precursors 2-carbohydrazides, bearing thienopyridine moiety, were prepared using 2-thioxopyridine-3-carbonitriles as key synthons. Next, 2-carbohydrazides were reacted with a variety of 4-substituted benzylidinemalononitriles or 4-substituted benzaldehydes to afford a new series of the target hydrazones incorporating thienopyridine moiety. The elemental analyses and spectral data were used to demonstrate the structures of new hydrazones series. The in vitro antibacterial activities of the target hydrazones were evaluated against different strains of Gram-positive and Gram-negative bacteria. In comparison with chloramphenicol as a reference drug, hydrazones 13b, 13c and 13d, linked to p-C1, p-Br and p-Me moiety, respectively, exhibited the strongest activities against all tested bacteria with MIC values in the range of 6.2-12.5 mu g/mL. In addition, several new hydrazones were tested as in vitro cytotoxic agents against each of human breast carcinoma MCF-7 cell line, colon cancer Caco2 cell line and liver hepatocellular carcinoma HEPG2 cell line. The hydrazones 13b, 13c and 13d demonstrated the best cytotoxicity against the tested eukaryotic cells. Furthermore, both experimental and docking studies could predict the promising inhibitory activities of hydrazones 13c and 13d against COX-2 enzyme with IC 50 of 0.110 and 0.104 mu M, respectively, when compared with Celecoxib (IC50 of 0.115 mu M). [GRAPHICS] .

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Name: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Theoretical and computational insight into the supramolecular assemblies of Schiff bases involving hydrogen bonding and C-H center dot center dot center dot pi interactions: Synthesis, X-ray characterization, Hirshfeld surface analysis, anticancer activity and molecular docking analysis WOS:000694717600005 published article about DENSITY-FUNCTIONAL THEORY; HOMO-LUMO ANALYSES; COORDINATION-COMPLEXES; FT-RAMAN; THERMODYNAMIC FUNCTIONS; CRYSTAL-STRUCTURE; SIGMA-HOLE; RECEPTORS; DFT; ASSOCIATION in [Andleeb, Hina; Hameed, Shahid] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan; [Andleeb, Hina; Danish, Lubna; Munawar, Shiza] Int Islamic Univ, Fac Basic & Appl Sci, Sulaiman Bin Abdullah Aba Al Khail Ctr Interdisci, Islamabad, Pakistan; [Ahmed, Muhammad Naeem] Univ Azad Jammu & Kashmir, Dept Chem, Muzaffarabad 13100, Pakistan; [Khan, Imtiaz; Ali, Hafiz Saqib] Univ Manchester, Dept Chem, 131 Princess St, Manchester M1 7DN, Lancs, England; [Khan, Imtiaz; Ali, Hafiz Saqib] Univ Manchester, Manchester Inst Biotechnol, 131 Princess St, Manchester M1 7DN, Lancs, England; [Tahir, Muhammad Nawaz] Univ Sargodha, Dept Phys, Sargodha, Pakistan; [Simpson, Jim] Univ Otago, Dept Chem, POB 56, Dunedin 9054, New Zealand in 2021.0, Cited 114.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Formula: C8H7NO3

The present study examines the significance of various non-covalent interactions in the supramolecular assembly of (E)-1-(1-(4-nitrophenyl)ethylidene)-2-phenylhydrazine 1c and (E)-3-bromo-N’-(1-phenylethylidene)benzohydrazide 2d. The synthesized compounds were fully characterized by spectroscopic methods and single crystal X-ray diffraction analysis. The topology of the supramolecular assemblies was controlled by various non-covalent interactions including classical hydrogen bonding, C-H center dot center dot center dot pi and Br center dot center dot center dot Br interactions which were examined in detail using several theoretical methods and DFT calculations. The optimized geometric parameters of compounds 1c and 2d were calculated using density functional theory (DFT/B3LYP) quantum chemical method with the 6-311++G(d,p) basis set using the crystallographic coordinates. Additionally, fragments contributing to the HOMO and LUMO molecular orbitals were investigated at the same level of theory. The nature and various types of intermolecular interactions in the crystal structures was also investigated by Hirshfeld surface analysis. The synthesized Schiff bases were also studied for their potential as drugs and physicochemical properties. Bioevaluation against four cancer cell lines (NCI-H460, NCI-H460/Bcl-2, MDA-MB-231 and MCF-7) showed that compound 1c was a more potent inducer of toxicity compared to 2d. The putative binding modes of the bioactive Schiff bases were investigated using molecular docking tools and the results revealed that both the inhibitors were stabilized in the active pocket of the enzyme via the formation of various interactions with the key amino acid residues. (C) 2021 Elsevier B.V. All rights reserved.

Welcome to talk about 100-19-6, If you have any questions, you can contact Andleeb, H; Danish, L; Munawar, S; Ahmed, MN; Khan, I; Ali, HS; Tahir, MN; Simpson, J; Hameed, S or send Email.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem