Recommanded Product: 100-19-6. Recently I am researching about ONE-POT SYNTHESIS; ACTIVE METHYLENE ISOCYANIDES; SOLID-PHASE SYNTHESIS; AEROBIC OXIDATION; QUINOXALINE DERIVATIVES; REGIOSPECIFIC SYNTHESIS; EFFICIENT PROTOCOL; TERMINAL ALKYNES; FACILE SYNTHESIS; AMIDE HYDROLASE, Saw an article supported by the University Grants Commission-Special Assistance Programme, Departmental Research Support (UGC-SAP DRS III). Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Kiran, KR; Swaroop, TR; Sukrutha, KP; Shruthi, JB; Anil, SM; Rangappa, KS; Sadashiva, MP. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
o-Phenylenediammines ando-aminophenols were reacted with alpha-oxodithioesters in a highly regioselective fashion to give 2-methylthio-3-aryl/heteroarylquinoxalines and 2-acylbenzoxazoles in 55-94% and 45-86%, respectively, in the presence ofp-toluene sulfonic acid catalyst. Control experiments involving reaction of aniline with a alpha-oxodithioester indicated that the thiocarbonyl group is more reactive than the carbonyl group. Based on this, probable mechanisms for the formation of quinoxalines and benzoxazoles are given. Biological targets of the quinoxalines and benzoxazoles were identified by bioinformatics. It was found that quinoxalines have good binding affinity with human dual-specificity tyrosine-phosphorylation-regulated kinase 1A and benzoxazoles with human carboxylesterase.
Recommanded Product: 100-19-6. Welcome to talk about 100-19-6, If you have any questions, you can contact Kiran, KR; Swaroop, TR; Sukrutha, KP; Shruthi, JB; Anil, SM; Rangappa, KS; Sadashiva, MP or send Email.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem