I found the field of Chemistry very interesting. Saw the article Acid-Catalyzed Condensation of o-Phenylenediammines and o-Aminophenols with alpha-Oxodithioesters: A Divergent and Regio-selective Synthesis of 2-Methylthio-3-aryl/Heteroarylquinoxalines and 2-Acylbenzoxazoles published in 2019.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone, Reprint Addresses Rangappa, KS; Sadashiva, MP (corresponding author), Univ Mysore, Dept Studies Chem, Mysuru 570006, Karnataka, India.; Swaroop, TR (corresponding author), Univ Mysore, Dept Studies Organ Chem, Mysuru 570006, Karnataka, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
o-Phenylenediammines ando-aminophenols were reacted with alpha-oxodithioesters in a highly regioselective fashion to give 2-methylthio-3-aryl/heteroarylquinoxalines and 2-acylbenzoxazoles in 55-94% and 45-86%, respectively, in the presence ofp-toluene sulfonic acid catalyst. Control experiments involving reaction of aniline with a alpha-oxodithioester indicated that the thiocarbonyl group is more reactive than the carbonyl group. Based on this, probable mechanisms for the formation of quinoxalines and benzoxazoles are given. Biological targets of the quinoxalines and benzoxazoles were identified by bioinformatics. It was found that quinoxalines have good binding affinity with human dual-specificity tyrosine-phosphorylation-regulated kinase 1A and benzoxazoles with human carboxylesterase.
Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem